| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Björn Wito Walthe. Treating restless legs syndrome: current pathophysiological concepts and clinical trials. Expert opinion on investigational drugs. vol 11. issue 4. 2002-08-15. PMID:11922859. |
one of the outstanding characteristics of restless legs syndrome is its extreme responsiveness to dopaminergic agents. |
2002-08-15 |
2023-08-12 |
Not clear |
| A Desautels, G Turecki, J Montplaisir, K Brisebois, A Sequeira, B Adam, G A Roulea. Evidence for a genetic association between monoamine oxidase A and restless legs syndrome. Neurology. vol 59. issue 2. 2002-08-07. PMID:12136060. |
impairment in the central dopaminergic system has been consistently suggested as an etiologic factor in restless legs syndrome (rls). |
2002-08-07 |
2023-08-12 |
Not clear |
| E K Tan, S Y Lum, M C Won. Restless legs syndrome in Parkinson's disease. Journal of the neurological sciences. vol 196. issue 1-2. 2002-06-21. PMID:11959153. |
recent clinical and functional imaging data suggest impaired central dopaminergic transmission in restless legs syndrome (rls). |
2002-06-21 |
2023-08-12 |
Not clear |
| B Jakobsson, K Ruut. Successful treatment of restless legs syndrome with an implanted pump for intrathecal drug delivery. Acta anaesthesiologica Scandinavica. vol 46. issue 1. 2002-05-08. PMID:11903084. |
two patients with incapacitating symptoms from restless legs syndrome, not adequately responding to conventional treatment with dopaminergic drugs, were implanted with a pump device (isomed) for intrathecal delivery of morphine and bupivacaine. |
2002-05-08 |
2023-08-12 |
Not clear |
| William G Ondo, Kevin Dat Vuong, Joseph Jankovi. Exploring the relationship between Parkinson disease and restless legs syndrome. Archives of neurology. vol 59. issue 3. 2002-03-27. PMID:11890847. |
restless legs syndrome (rls) and parkinson disease (pd) are common neurological conditions that respond to dopaminergic therapy. |
2002-03-27 |
2023-08-12 |
Not clear |
| K Stiasn. Clinical data on restless legs syndrome: a dose-finding study with cabergoline. European neurology. vol 46 Suppl 1. 2002-02-21. PMID:11741100. |
current treatment options for restless legs syndrome (rls), based on the american academy of sleep medicine practice parameters, favor dopaminergic agents. |
2002-02-21 |
2023-08-12 |
Not clear |
| A Desautels, G Turecki, J Montplaisir, N Ftouhi-Paquin, M Michaud, V A Chouinard, G A Roulea. Dopaminergic neurotransmission and restless legs syndrome: a genetic association analysis. Neurology. vol 57. issue 7. 2001-11-01. PMID:11591853. |
dopaminergic neurotransmission and restless legs syndrome: a genetic association analysis. |
2001-11-01 |
2023-08-12 |
Not clear |
| A Desautels, G Turecki, J Montplaisir, N Ftouhi-Paquin, M Michaud, V A Chouinard, G A Roulea. Dopaminergic neurotransmission and restless legs syndrome: a genetic association analysis. Neurology. vol 57. issue 7. 2001-11-01. PMID:11591853. |
in order to examine the genetic substrate of the dopamine hypothesis in restless legs syndrome, we analyzed eight genes coding for receptors and enzymes related to dopaminergic transmission, using a population of 92 patients with restless legs syndrome and 182 controls matched for ethnic background. |
2001-11-01 |
2023-08-12 |
Not clear |
| M H Silbe. Sleep disorders. Neurologic clinics. vol 19. issue 1. 2001-08-09. PMID:11471763. |
a range of dopaminergic agents is available to treat restless legs syndrome; other medications such as opiates, benzodiazepines, and anticonvulsants can also be used. |
2001-08-09 |
2023-08-12 |
Not clear |
| M Saletu, P Anderer, G Saletu-Zyhlarz, W Prause, B Semler, A Zoghlami, G Gruber, C Hauer, B Salet. Restless legs syndrome (RLS) and periodic limb movement disorder (PLMD): acute placebo-controlled sleep laboratory studies with clonazepam. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 2. 2001-07-05. PMID:11313161. |
restless legs syndrome (rls) - a common sensorimotor disorder - and periodic limb movement disorder (plmd) are currently treated with substances of four classes: dopaminergic agents, which are considered the drugs of choice, benzodiazepines, opioids and anticonvulsants. |
2001-07-05 |
2023-08-12 |
Not clear |
| C J Earley, K Hyland, R P Alle. CSF dopamine, serotonin, and biopterin metabolites in patients with restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 16. issue 1. 2001-06-14. PMID:11215576. |
to evaluate the role of cns dopaminergic systems in restless legs syndrome (rls), homovanillic acid (hva), tetrahydrobiopterin (bh4), and neopterin (neop), were assayed in csf from rls patients. |
2001-06-14 |
2023-08-12 |
Not clear |
| L K Brown, J E Heffner, E A Obben. Transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen. Sleep. vol 23. issue 5. 2000-12-14. PMID:10947026. |
transverse myelitis associated with restless legs syndrome and periodic movements of sleep responsive to an oral dopaminergic agent but not to intrathecal baclofen. |
2000-12-14 |
2023-08-12 |
Not clear |
| W G Ondo, Y He, S Rajasekaran, W D L. Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats: a possible model for restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 15. issue 1. 2000-02-10. PMID:10634257. |
clinical correlates of 6-hydroxydopamine injections into a11 dopaminergic neurons in rats: a possible model for restless legs syndrome. |
2000-02-10 |
2023-08-12 |
rat |
| W G Ondo, Y He, S Rajasekaran, W D L. Clinical correlates of 6-hydroxydopamine injections into A11 dopaminergic neurons in rats: a possible model for restless legs syndrome. Movement disorders : official journal of the Movement Disorder Society. vol 15. issue 1. 2000-02-10. PMID:10634257. |
pursuant to the clinical suspicion that restless legs syndrome (rls) may involve dopaminergic diencephalic spinal neurons (a11), we performed stereotaxic bilateral 6-hydroxydopamine (6-ohda) lesions into the a11 nucleus to observe for any behavioral correlates similar to this clinical condition. |
2000-02-10 |
2023-08-12 |
rat |
| N Turjanski, A J Lees, D J Brook. Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies. Neurology. vol 52. issue 5. 1999-05-06. PMID:10102408. |
striatal dopaminergic function in restless legs syndrome: 18f-dopa and 11c-raclopride pet studies. |
1999-05-06 |
2023-08-12 |
Not clear |
| N Turjanski, A J Lees, D J Brook. Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies. Neurology. vol 52. issue 5. 1999-05-06. PMID:10102408. |
to use pet to study striatal dopaminergic function in restless legs syndrome (rls). |
1999-05-06 |
2023-08-12 |
Not clear |
| S C Lin, J Kaplan, C D Burger, P A Fredrickso. Effect of pramipexole in treatment of resistant restless legs syndrome. Mayo Clinic proceedings. vol 73. issue 6. 1998-06-18. PMID:9621854. |
to report the results of an open-label trial with a dopaminergic agent, pramipexole, in patients with treatment-resistant restless legs syndrome (rls). |
1998-06-18 |
2023-08-12 |
Not clear |
| b' A L\\xc3\\xb3pez de Munain, J J Poza, A Gorospe, A Arce, J F Mart\\xc3\\xad Mass\\xc3\\xb. Tardive akathisia due to sulpiride. Clinical neuropharmacology. vol 17. issue 5. 1997-10-23. PMID:9316700.' |
ta seems to be related with an apparent dopaminergic hyperactivity and it has to be differentiated of other neuroleptic-induced movement disorders such as restless legs syndrome in order of an appropriate treatment. |
1997-10-23 |
2023-08-12 |
Not clear |
| C H Adle. Treatment of restless legs syndrome with gabapentin. Clinical neuropharmacology. vol 20. issue 2. 1997-06-18. PMID:9099467. |
restless legs syndrome (rls) is a disorder characterized by sensory and motor symptoms in the legs that is best treated with dopaminergic drugs and opiates. |
1997-06-18 |
2023-08-12 |
Not clear |
| P M Becker, A O Jamieson, W D Brow. Dopaminergic agents in restless legs syndrome and periodic limb movements of sleep: response and complications of extended treatment in 49 cases. Sleep. vol 16. issue 8. 1994-05-24. PMID:7909374. |
dopaminergic agents in restless legs syndrome and periodic limb movements of sleep: response and complications of extended treatment in 49 cases. |
1994-05-24 |
2023-08-12 |
human |