| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Akiyama, M Sato, K Kashihara, S Otsuk. Lasting changes in high affinity 3H-spiperone binding to the rat striatum and mesolimbic area after chronic methamphetamine administration: evaluation of dopaminergic and serotonergic receptor components. Biological psychiatry. vol 17. issue 12. 1983-04-07. PMID:7159638. |
dopaminergic receptor component was displaced by 10 microm 2-amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene (adtn), and serotonergic receptor component by 0.2 microm mianserin. |
1983-04-07 |
2023-08-12 |
rat |
| H Khachaturian, S J Watso. Some perspectives on monoamine-opioid peptide interaction in rat central nervous system. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6129045. |
these included several thalamic and hypothalamic nuclei, several limbic structures, mesencephalic periaqueductal gray, brain stem noradrenergic cell groups and their rostral projections, the dopaminergic nigrostriatal system, and the serotonergic raphe nuclei and their projections. |
1983-02-25 |
2023-08-12 |
rat |
| J A Wallace, P Petrusz, J M Laude. Serotonin immunocytochemistry in the adult and developing rat brain: methodological and pharmacological considerations. Brain research bulletin. vol 9. issue 1-6. 1983-02-25. PMID:6756548. |
rather, since the staining could be inhibited by pretreatment with the catecholaminergic uptake blocker desmethylimipramine, it is postulated that this effect may be due to either (1) the non-specific uptake of 5-ht or 5-hydroxytryptophan (5-htp) into the dopaminergic cells of a9 and a10 due to elevated levels of these substances in the dense serotonergic axonal plexus passing through this region or (2) to an increased uptake of circulating l-tryptophan by these a9 and a10 cells followed by conversion of this amino acid to tryptamine by aromatic amine decarboxylase, an enzyme common to both 5-ht and dopaminergic neurons. |
1983-02-25 |
2023-08-12 |
rat |
| D A Bennett, H La. Discriminative stimuli produced by clonidine: an investigation of the possible relationship to adrenoceptor stimulation and hypotension. The Journal of pharmacology and experimental therapeutics. vol 223. issue 3. 1983-01-27. PMID:6292393. |
the clonidine stimulus was dose-dependently antagonized by the alpha-2 adrenergic antagonist, yohimbine, whereas receptor antagonists of alpha-1 adrenergic, beta adrenergic, dopaminergic, serotonergic, cholinergic or opioid systems were ineffective in blocking the interoceptive stimulus produced by clonidine lofexidine, guanabenz and methyldopa, all centrally acting hypotensive drugs that act through alpha-2 adrenoceptor mechanisms dose-dependently generalized to the clonidine cue, whereas hydralazine, minoxidil, propranolol and prazosin, hypotensive drugs acting through other mechanisms, did not generalize. |
1983-01-27 |
2023-08-12 |
rat |
| M D Schechter, J T Concanno. Dopaminergic activity of quipazine. Pharmacology, biochemistry, and behavior. vol 17. issue 3. 1983-01-07. PMID:7146043. |
these results evidence a dopaminergic action for quipazine and suggest that central serotonergic and dopaminergic pathways may interact cooperatively to control behavior. |
1983-01-07 |
2023-08-12 |
rat |
| W H Hs. Xylazine-induced delay of small intestinal transit in mice. European journal of pharmacology. vol 83. issue 1-2. 1982-12-21. PMID:7128700. |
these results suggest that xylazine-induced delay of small intestinal transit is mediated by postjunctional alpha 2-adrenoceptors and appears not to involve activation of opioid, cholinergic, dopaminergic, histaminergic, or serotonergic receptors. |
1982-12-21 |
2023-08-12 |
mouse |
| M Kawakami, S Ohn. Effects of diethyldithiocarbamate (DDC), fusaric acid, catecholaminergic and serotonergic receptor blockers on the ascending pathway from the ventrolateral part of the medulla oblongata. Endocrinologia japonica. vol 29. issue 2. 1982-12-16. PMID:6290207. |
percentages of facilitatory and inhibitory responses were not changed significantly after injection of pimozide, a dopaminergic receptor blocker, or methysergide, a serotonergic receptor blocker. |
1982-12-16 |
2023-08-12 |
rat |
| J J Feigenbaum, J Yanai, H L Klawan. The comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced locomotor activity. Journal of neural transmission. vol 54. issue 3-4. 1982-12-16. PMID:7130970. |
the comparative roles of dopaminergic and serotonergic mechanisms in mediating quipazine induced locomotor activity. |
1982-12-16 |
2023-08-12 |
Not clear |
| H Schoemaker, T P Davis, N W Pedigo, A Chen, E S Berens, P Ragan, N C Ling, H I Yamamur. Identification of beta-endorphin-6(16-17) as the principal metabolite of des-tyrosin-gamma-endorphin (DTgammaE) in vitro and assessment of its activity in neurotransmitter receptor binding assays. European journal of pharmacology. vol 81. issue 3. 1982-12-02. PMID:6126374. |
neurotransmitter receptor binding experiments showed that beta-endorphin-(6-17) was inactive at central dopaminergic, serotonergic, muscarinic, benzodiazepine and opiate receptors measured in vitro. |
1982-12-02 |
2023-08-12 |
rat |
| L Grandiso. Suppression of prolactin secretion by benzodiazepines in vivo. Neuroendocrinology. vol 34. issue 5. 1982-07-22. PMID:6979001. |
diazepam administration also blunted the release of prolactin induced by dopaminergic receptor blockade following haloperidol, or by serotonergic receptor activation produced by fluoxetine, a serotonergic reuptake inhibitor plus 5-hydroxytryptophan, a serotonin precursor. |
1982-07-22 |
2023-08-12 |
rat |
| L Turski, J Czuczwar, W Turski, Z Kleinro. Induction of wet dog shakes by intracerebroventricular bethanechol in rats. Antagonism by neurotransmitter receptor blockers. Pharmacology. vol 24. issue 2. 1982-07-08. PMID:6281815. |
wds induced by bethanechol at the dose of 100 micrograms was antagonized by atropine, scopolamine and spiperone (muscarinic cholinergic and dopaminergic antagonists, respectively), whilst metergoline, methysergide, phentolamine, propranolol and bicuculline (serotonergic, alpha-adrenergic, beta-adrenergic and gaba-ergic antagonists) fail to inhibit this effect. |
1982-07-08 |
2023-08-12 |
rat |
| M E Trulson, J W Brandstetter, T Crisp, B L Jacob. Behavioral effects of quipazine in the cat. European journal of pharmacology. vol 78. issue 3. 1982-06-21. PMID:6461558. |
the mechanism of action of quipazine, as well as the neuropharmacology of the limb flick model, is discussed in the content of these studies with serotonergic and dopaminergic drugs. |
1982-06-21 |
2023-08-12 |
cat |
| A Plec. Psychopharmacological effects of cholinomimetic agents administered into hippocampus and various hypothalamic areas in the rat. Thesis. Polish journal of pharmacology and pharmacy. vol 33. issue 4. 1982-04-12. PMID:7329867. |
the presence of functional interaction between cholinergic and dopaminergic and serotonergic neurons in the rat anterior hypothalamus has been shown. |
1982-04-12 |
2023-08-12 |
rat |
| J L Marin. Serotonergic and dopaminergic effects of yawning in the cat. Pharmacology, biochemistry, and behavior. vol 15. issue 5. 1982-02-12. PMID:7312907. |
serotonergic and dopaminergic effects of yawning in the cat. |
1982-02-12 |
2023-08-12 |
cat |
| J L Marin. Serotonergic and dopaminergic effects of yawning in the cat. Pharmacology, biochemistry, and behavior. vol 15. issue 5. 1982-02-12. PMID:7312907. |
given that lisuride has more potent dopamine agonist properties than lsd, these results are consistent with serotonergic elicitation of yawning, dopaminergic inhibition of yawning, and with their concomitant interaction in the expression of drug-induced yawning in the cat. |
1982-02-12 |
2023-08-12 |
cat |
| K J Watling, L L Iverse. Comparison of the binding of [3H]spiperone and [3H]domperidone in homogenates of mammalian retina and caudate nucleus. Journal of neurochemistry. vol 37. issue 5. 1982-01-28. PMID:7299392. |
the pharmacological analysis of [3h]spiperone binding in both the bovine retina and caudate nucleus indicated an interaction with dopaminergic rather than serotonergic sites. |
1982-01-28 |
2023-08-12 |
cattle |
| R M Withy, R J Mayer, P G Strang. Use of [3H]spiperone for labelling dopaminergic and serotonergic receptors in bovine caudate nucleus. Journal of neurochemistry. vol 37. issue 5. 1982-01-28. PMID:7299393. |
use of [3h]spiperone for labelling dopaminergic and serotonergic receptors in bovine caudate nucleus. |
1982-01-28 |
2023-08-12 |
cattle |
| R M Withy, R J Mayer, P G Strang. Use of [3H]spiperone for labelling dopaminergic and serotonergic receptors in bovine caudate nucleus. Journal of neurochemistry. vol 37. issue 5. 1982-01-28. PMID:7299393. |
saturation binding experiments have been conducted on each class of site, defining dopaminergic binding of [3h]spiperone as that binding displaced by 0.1 mm-dopamine and serotonergic binding as that displaced by 0.3 microm-mianserin. |
1982-01-28 |
2023-08-12 |
cattle |
| K Kawanishi, Y Hashimoto, M Fujiwara, Y Kataoka, S Uek. Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. Journal of pharmacobio-dynamics. vol 4. issue 7. 1982-01-20. PMID:6975366. |
these findings suggest that a catecholaminergic (particularly dopaminergic) and serotonergic system imbalance plays an important role in the manifestation of harmine tremor. |
1982-01-20 |
2023-08-12 |
mouse |
| V Bhargava, A Salamy, S Sha. Role of serotonin in the nicotine-induced depression of the brainstem auditory evoked response. Pharmacology, biochemistry, and behavior. vol 15. issue 4. 1981-12-22. PMID:6457306. |
we have examined the role of serotonergic and/or dopaminergic mechanism in the mediation of the nicotine-induced depression of brainstem auditory evoked responses (baer) to auditory stimuli. |
1981-12-22 |
2023-08-12 |
Not clear |