| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolás Cano-Astorga, Sergio Plaza-Alonso, Marta Turegano-Lopez, José Rodrigo-Rodríguez, Angel Merchan-Perez, Javier DeFelip. Unambiguous identification of asymmetric and symmetric synapses using volume electron microscopy. Frontiers in neuroanatomy. vol 18. 2024-04-22. PMID:38645671. |
in the cerebral cortex, since most as are excitatory (glutamatergic), and ss are inhibitory (gabaergic), determining the distribution, size, density, and proportion of the two major cortical types of synapses is critical, not only to better understand synaptic organization in terms of connectivity, but also from a functional perspective. |
2024-04-22 |
2024-04-24 |
mouse |
| Irina Topchiy, Julie Mohbat, Oluwarotimi O Folorunso, Ziyi Zephyr Wang, Cayetana Lazcano-Etchebarne, Elif Engi. GABA System as the Cause and Effect in Early Development. Neuroscience and biobehavioral reviews. 2024-04-05. PMID:38579901. |
in the developing brain, the development of gabaergic neurons precedes that of glutamatergic neurons and the gaba system serves as a guide and framework for the development of other brain systems. |
2024-04-05 |
2024-04-10 |
Not clear |
| Boxuan Li, Shizhe Deng, Hailun Jiang, Weiming Zhu, Bifang Zhuo, Yuzheng Du, Zhihong Men. The mechanistic effects of acupuncture in rodent neurodegenerative disease models: a literature review. Frontiers in neuroscience. vol 18. 2024-03-19. PMID:38500484. |
here, we reviewed the therapeutic mechanisms of acupuncture at the neural circuit level in movement and cognition disorders, summarizing the influence of acupuncture in the dopaminergic system, glutamatergic system, γ-amino butyric acid-ergic (gabaergic) system, serotonergic system, cholinergic system, and glial cells at the circuit and synaptic levels. |
2024-03-19 |
2024-03-21 |
Not clear |
| Alice Bertero, Alfonso Junior Apicell. Distinct electrophysiological properties of long-range GABAergic and glutamatergic neurons from the lateral amygdala to the auditory cortex of the mouse. The Journal of physiology. 2024-03-17. PMID:38493320. |
distinct electrophysiological properties of long-range gabaergic and glutamatergic neurons from the lateral amygdala to the auditory cortex of the mouse. |
2024-03-17 |
2024-03-19 |
mouse |
| Alice Bertero, Alfonso Junior Apicell. Distinct electrophysiological properties of long-range GABAergic and glutamatergic neurons from the lateral amygdala to the auditory cortex of the mouse. The Journal of physiology. 2024-03-17. PMID:38493320. |
multiple approaches, including anatomical studies, electrophysiological investigations, imaging techniques, optogenetics and chemogenetics, have confirmed that the auditory cortex (ac) impacts fear-related behaviours driven by auditory stimuli by conveying auditory information to the lateral amygdala (la) through long-range excitatory glutamatergic and gabaergic connections. |
2024-03-17 |
2024-03-19 |
mouse |
| Jessica E Childs, Samuel Morabito, Sudeshna Das, Caterina Santelli, Victoria Pham, Kelly Kusche, Vanessa Alizo Vera, Fairlie Reese, Rianne R Campbell, Dina P Matheos, Vivek Swarup, Marcelo A Woo. Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice. Cell reports. vol 43. issue 3. 2024-03-15. PMID:38489267. |
we use single-nucleus transcriptomics to characterize the molecular cascade following nr4a2 manipulation, revealing changes in transcriptional networks related to addiction, neuroplasticity, and gabaergic and glutamatergic signaling. |
2024-03-15 |
2024-03-18 |
mouse |
| Tsubasa Itoh, Mari Uehara, Shinnosuke Yura, Jui Chun Wang, Yukimi Fujii, Akiko Nakanishi, Takashi Shimizu, Masahiko Hib. Foxp- and Skor-family proteins control differentiation of Purkinje cells from Ptf1a and Neurogenin1-expressing progenitors in zebrafish. Development (Cambridge, England). 2024-03-08. PMID:38456494. |
cerebellar neurons, such as gabaergic purkinje cells (pcs), interneurons (ins), and glutamatergic granule cells (gcs) are differentiated from neural progenitors expressing proneural genes including ptf1a, neurogenin1, and atoh1a/b/c. |
2024-03-08 |
2024-03-10 |
zebrafish |
| Johanna Heider, Aaron Stahl, Denise Sperlich, Sophia-Marie Hartmann, Sabrina Vogel, Ricarda Breitmeyer, Markus Templin, Hansjürgen Volkme. Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons. BMC neuroscience. vol 25. issue 1. 2024-03-04. PMID:38438989. |
defined co-cultures of glutamatergic and gabaergic neurons with a mutation in disc1 reveal aberrant phenotypes in gabaergic neurons. |
2024-03-04 |
2024-03-07 |
Not clear |
| Johanna Heider, Aaron Stahl, Denise Sperlich, Sophia-Marie Hartmann, Sabrina Vogel, Ricarda Breitmeyer, Markus Templin, Hansjürgen Volkme. Defined co-cultures of glutamatergic and GABAergic neurons with a mutation in DISC1 reveal aberrant phenotypes in GABAergic neurons. BMC neuroscience. vol 25. issue 1. 2024-03-04. PMID:38438989. |
in this study, we made use of an isogenic cell line with a mutation in disc1 to study neuronal synaptic phenotypes in a culture system comprising a defined ratio of ngn2 and ascl1/dlx2 (ad2)-transduced neurons, enriched for glutamatergic and gabaergic neurons, respectively, to mimic properties of the cortical microcircuitry. |
2024-03-04 |
2024-03-07 |
Not clear |
| Huanliang Liu, Xiaochao Tan, Yu Wu, Xiaona Li, Zhiyong Hu, Shuhan Lei, Wendong Fan, Zhenyu Wan. Long-term exposure to 6-PPD quinone at environmentally relevant concentrations causes neurotoxicity by affecting dopaminergic, serotonergic, glutamatergic, and GABAergic neuronal systems in Caenorhabditis elegans. The Science of the total environment. 2024-02-29. PMID:38423311. |
lastly, pearson's correlation analysis showed that locomotion behavior and sensory perception behavior were positively correlated with the dopaminergic, serotonergic, glutamatergic, and gabaergic neurotransmission. |
2024-02-29 |
2024-03-03 |
caenorhabditis_elegans |
| George Ntoulas, Charalampos Brakatselos, Gerasimos Nakas, Michail-Zois Asprogerakas, Foteini Delis, Leonidas J Leontiadis, George Trompoukis, Costas Papatheodoropoulos, Dimitrios Gkikas, Dimitrios Valakos, Giannis Vatsellas, Panagiotis K Politis, Alexia Polissidis, Katerina Antonio. Multi-level profiling of the Fmr1 KO rat unveils altered behavioral traits along with aberrant glutamatergic function. Translational psychiatry. vol 14. issue 1. 2024-02-20. PMID:38378836. |
therefore, we employed a multi-level approach to study the behavioral profile and the glutamatergic and gabaergic neurotransmission status in pathophysiology-associated brain structures of fmr1 ko rats, including the recordings of evoked and spontaneous field potentials from hippocampal slices, paralleled with next-generation rna sequencing (rna-seq). |
2024-02-20 |
2024-02-23 |
mouse |
| George Ntoulas, Charalampos Brakatselos, Gerasimos Nakas, Michail-Zois Asprogerakas, Foteini Delis, Leonidas J Leontiadis, George Trompoukis, Costas Papatheodoropoulos, Dimitrios Gkikas, Dimitrios Valakos, Giannis Vatsellas, Panagiotis K Politis, Alexia Polissidis, Katerina Antonio. Multi-level profiling of the Fmr1 KO rat unveils altered behavioral traits along with aberrant glutamatergic function. Translational psychiatry. vol 14. issue 1. 2024-02-20. PMID:38378836. |
we found that these rats exhibit hyperactivity and cognitive deficits, along with characteristic bidirectional glutamatergic and gabaergic alterations in the prefrontal cortex and the hippocampus. |
2024-02-20 |
2024-02-23 |
mouse |
| Marcelo Mendonça-Dos-Santos, Thaís Cristina Teixeira Gonçalves, Luiz Luciano Falconi-Sobrinho, Tayllon Dos Anjos-Garcia, Ivair Matias, Rithiele Cristina de Oliveira, Maria de Fátima Dos Santos Sampaio, Fabrízio Dos Santos Cardoso, Wagner Ferreira Dos Santos, Helio Rubens Machado, Norberto Cysne Coimbr. GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception neuromodulation. Scientific reports. vol 14. issue 1. 2024-02-20. PMID:38374419. |
gabaergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception neuromodulation. |
2024-02-20 |
2024-02-22 |
rat |
| Marcelo Mendonça-Dos-Santos, Thaís Cristina Teixeira Gonçalves, Luiz Luciano Falconi-Sobrinho, Tayllon Dos Anjos-Garcia, Ivair Matias, Rithiele Cristina de Oliveira, Maria de Fátima Dos Santos Sampaio, Fabrízio Dos Santos Cardoso, Wagner Ferreira Dos Santos, Helio Rubens Machado, Norberto Cysne Coimbr. GABAergic and glutamatergic inputs to the medulla oblongata and locus coeruleus noradrenergic pathways are critical for seizures and postictal antinociception neuromodulation. Scientific reports. vol 14. issue 1. 2024-02-20. PMID:38374419. |
glutamatergic vesicles were found on dendrites and perikarya of gabaergic interneurons in the nts. |
2024-02-20 |
2024-02-22 |
rat |
| Ya He, Kang Ouyang, Hui Yang, Liangmou Wang, Xinyu Wang, Dapeng Li, Li L. The impact of ammonia and microcystin-LR on neurobehavior and glutamate/gamma-aminobutyric acid balance in female zebrafish (Danio rerio): ROS and inflammation as key pathways. The Science of the total environment. 2024-02-14. PMID:38354808. |
furthermore, both ammonia and mc-lr significantly changed the expression of genes related to the glutamatergic and gabaergic systems, elevated glu and gaba contents, as well as increased the glu/gaba ratio, indicating that a shift towards increased glu levels. |
2024-02-14 |
2024-02-17 |
zebrafish |
| Ahlem Assali, George Chenaux, Jennifer Y Cho, Stefano Berto, Nathan A Ehrlich, Christopher W Cowa. EphB1 controls proper long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells. Development (Cambridge, England). 2024-02-12. PMID:38345254. |
interestingly, in ephb1 ckovgat mice, the misguided axon bundles contained comingled striatal gabaergic and somatosensory cortical glutamatergic axons. |
2024-02-12 |
2024-02-15 |
mouse |
| Ahlem Assali, George Chenaux, Jennifer Y Cho, Stefano Berto, Nathan A Ehrlich, Christopher W Cowa. EphB1 controls proper long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells. Development (Cambridge, England). 2024-02-12. PMID:38345254. |
in wildtype mice, somatosensory axons also co-fasciculated with striatal axons notably in the globus pallidus, suggesting that a subset of glutamatergic cortical axons normally follows long-range gabaergic axons to reach their targets. |
2024-02-12 |
2024-02-15 |
mouse |
| Ahlem Assali, George Chenaux, Jennifer Y Cho, Stefano Berto, Nathan A Ehrlich, Christopher W Cowa. EphB1 controls proper long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells. Development (Cambridge, England). 2024-02-12. PMID:38345254. |
together, our data reveal a new role for ephb1 in gabaergic neurons to influence proper cortical glutamatergic axon guidance during brain development. |
2024-02-12 |
2024-02-15 |
mouse |
| Jeffrey M Witkin, Hana Shafique, Jodi L Smith, Rok Cern. Is there a biochemical basis for purinergic P2X3 and P2X4 receptor antagonists to be considered as anti-seizure medications? Biochemical pharmacology. 2024-02-10. PMID:38341001. |
the data implicating p2x3 and p2x4 receptors in epilepsy includes the role played by atp in neuronal excitability and seizures, receptor localization, increased receptor expression in epileptic brain, the involvement of these receptors in seizure-associated inflammation, crosstalk between these purinergic receptors and neuronal processes involved in seizures (gabaergic and glutamatergic neurotransmission), and the significant attenuation of seizures and seizure-like activity with p2x receptor blockade. |
2024-02-10 |
2024-02-14 |
Not clear |
| Susannah S Adel, Zachary J Pranske, Tess F Kowalski, Nicole Kanzler, Roshni Ray, Catherine Carmona, Suzanne Paradi. Plexin-B1 and Plexin-B2 play non-redundant roles in GABAergic synapse formation. Molecular and cellular neurosciences. 2024-02-08. PMID:38331011. |
we previously demonstrated that semaphorin-4d (sema4d) regulates gabaergic synapse development in the mammalian hippocampus while having no effect on glutamatergic synapse development, and this effect occurs through binding to its high affinity receptor, plexin-b1. |
2024-02-08 |
2024-02-11 |
Not clear |