| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cátia Santa, Diana Rodrigues, Joana F Coelho, Sandra I Anjo, Vera M Mendes, Diogo Bessa-Neto, Michael J Dunn, David Cotter, Graça Baltazar, Patrícia Monteiro, Bruno Manada. Chronic treatment with D2-antagonist haloperidol leads to inhibitory/excitatory imbalance in striatal D1-neurons. Translational psychiatry. vol 13. issue 1. 2023-10-06. PMID:37803004. |
here, we performed proteomic analysis of striatum brain tissue and found more than 400 proteins significantly altered after 30 days of chronic haloperidol treatment in mice, namely proteins involved in glutamatergic and gabaergic synaptic transmission. |
2023-10-06 |
2023-10-15 |
mouse |
| Sara Mostafalou, Mohammad Abdollah. The susceptibility of humans to neurodegenerative and neurodevelopmental toxicities caused by organophosphorus pesticides. Archives of toxicology. 2023-10-03. PMID:37787774. |
apart from inhibiting the cholinesterase enzyme, op compounds are believed to cause other pathological mechanisms at both the extracellular level (cholinergic, serotonergic, dopaminergic, glutamatergic, and gabaergic synapses) and the intracellular level (oxidative stress, mitochondrial dysfunction, inflammation, autophagy, and apoptosis) that contribute to these disorders. |
2023-10-03 |
2023-10-07 |
human |
| Zachary N M Luyo, Abigail B Lawrence, Theodore G Stathopoulos, Darlene A Mitran. Localization and neurochemical identity of alpha1-adrenergic receptor-containing elements in the mouse locus coeruleus. Journal of chemical neuroanatomy. 2023-09-30. PMID:37777094. |
double labeling immunohistochemistry found the α1ar expressed in gfap-labeled astrocytes, in both gabaergic and glutamatergic axon terminals, and in a portion of the α1ar dendrites, colocalized with tyrosine hydroxylase (th, a marker for noradrenergic neurons). |
2023-09-30 |
2023-10-07 |
mouse |
| Mihai Ceanga, Vahid Rahmati, Holger Haselmann, Lars Schmidl, Daniel Hunter, Anna-Katherina Brauer, Sabine Liebscher, Jakob Kreye, Harald Prüss, Laurent Groc, Stefan Hallermann, Josep Dalmau, Alessandro Ori, Manfred Heckmann, Christian Gei. Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony. Cell reports. vol 42. issue 10. 2023-09-28. PMID:37768823. |
functional alterations are also reflected in widespread remodeling of the hippocampal proteome, including changes in glutamatergic and gabaergic neurotransmission. |
2023-09-28 |
2023-10-07 |
mouse |
| Jingbo Wang, Sabitha Joseph, Siv Vingill, Ekrem Dere, Lars Tatenhorst, Anja Ronnenberg, Paul Lingor, Christian Preisinger, Hannelore Ehrenreich, Jörg B Schulz, Judith Stegmülle. Loss of the parkinsonism-associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects. Journal of neurochemistry. 2023-09-27. PMID:37753846. |
nex-cre;fbxo7fl/fl mice revealed an increase in striatal dopamine concentrations, changes in the glutamatergic, gabaergic and dopaminergic pathways, astrogliosis and microgliosis and little or no neuronal loss in the striatum. |
2023-09-27 |
2023-10-07 |
mouse |
| Ahmed Faraz Khan, Quadri Adewale, Sue-Jin Lin, Tobias R Baumeister, Yashar Zeighami, Felix Carbonell, Nicola Palomero-Gallagher, Yasser Iturria-Medin. Patient-specific models link neurotransmitter receptor mechanisms with motor and visuospatial axes of Parkinson's disease. Nature communications. vol 14. issue 1. 2023-09-26. PMID:37752107. |
inter-individual variability in receptor mechanisms correlates with symptom severity along two distinct axes, representing motor and psychomotor symptoms with large gabaergic and glutamatergic contributions, and cholinergically-dominant visuospatial, psychiatric and memory dysfunction. |
2023-09-26 |
2023-10-07 |
Not clear |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
therefore, the aim of the present study was to evaluate the early developmental effect of oxytocin administration (p2 and p3 days, two doses, 5 μg/pup, s.c.) on the expression of 1) brain-derived neurotrophic factor (bdnf) isoforms and 2) gabaergic and glutamatergic markers in the male rat hippocampus. |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
furthermore, we evaluated the branching of dendrites of primary hippocampal gabaergic and glutamatergic neurons in response to incubation with oxytocin (1 μm). |
2023-09-23 |
2023-10-07 |
rat |
| Stanislava Bukatova, Alexandra Reichova, Zuzana Bacova, Jan Bako. Neonatal oxytocin treatment alters levels of precursor and mature BDNF forms and modifies the expression of neuronal markers in the male rat hippocampus. Neuropeptides. vol 102. 2023-09-23. PMID:37741113. |
incubation in a presence of oxytocin reduced branching of glutamatergic hippocampal neurons and the opposite stimulatory effect of oxytocin was observed in gabaergic neurons. |
2023-09-23 |
2023-10-07 |
rat |
| Lu Zhang, Chunqiao Lin, Jiushuang Zhu, Yan He, Meng Zhan, Xiuwen Xia, Ni Yang, Kun Yang, Baojia Wang, Zhanqion Zhong, Yili Wang, Weijun Ding, Youjun Yan. Restoring prefrontal cortical excitation-inhibition balance with cannabidiol ameliorates neurobehavioral abnormalities in a mouse model of neurodevelopmental disorders. Neuropharmacology. 2023-09-16. PMID:37716533. |
cannabidiol (cbd) effectively alleviated the behavioral abnormalities observed in mia offspring by reducing glutamatergic transmission and enhancing gabaergic neurotransmission of mpfc pyramidal neurons. |
2023-09-16 |
2023-10-07 |
mouse |
| Joseph V Martin, Pradip K Sarka. Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? Frontiers in endocrinology. vol 14. 2023-09-13. PMID:37701902. |
furthermore, thyronines bind specifically to other defined neurotransmitter receptors, including gabaergic, catecholaminergic, glutamatergic, serotonergic and cholinergic systems. |
2023-09-13 |
2023-10-07 |
Not clear |
| Jen-Hui Tsou, Syun-Ruei Lee, Chia-Ying Chiang, Yi-Jie Yang, Fong-Yi Guo, Shih-Ying Ni, Hau-Jie Ya. Negative emotions recruit the parabrachial nucleus efferent to the VTA to disengage instrumental food seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-09-08. PMID:37684032. |
lastly, we demonstrate that transient activation of vta glutamatergic, but not gabaergic, neurons recapitulates the negative regulation of the pbn input on food self-administration behavior. |
2023-09-08 |
2023-10-07 |
mouse |
| Nozomu H Nakamura, Yoshitaka Oku, Masaki Fukunag. "Brain-breath" interactions: respiration-timing-dependent impact on functional brain networks and beyond. Reviews in the neurosciences. 2023-08-31. PMID:37651646. |
to determine possible respiratory roles in attentional and memory processes and functional neural networks, we discussed how breathing interacts with the brain that are measured by electrophysiology and functional neuroimaging: (i) respiration-dependent modulation of mental health and cognition; (ii) respiratory rhythm generation and respiratory pontomedullary networks in the brainstem; (iii) respiration-dependent effects on specific brainstem regions and functional neural networks (e.g., glutamatergic prebötzinger complex neurons, gabaergic parafacial neurons, adrenergic c1 neurons, parabrachial nucleus, locus coeruleus, temporoparietal junction, default-mode network, ventral attention network, and cingulo-opercular salience network); and (iv) a potential application of breathing manipulation in mental health care. |
2023-08-31 |
2023-09-07 |
Not clear |
| Yannick Bollmann, Laura Modol, Thomas Tressard, Artem Vorobyev, Robin Dard, Sophie Brustlein, Ruth Sims, Imane Bendifallah, Erwan Leprince, Vincent de Sars, Emiliano Ronzitti, Agnès Baude, Hillel Adesnik, Michel Aimé Picardo, Jean-Claude Platel, Valentina Emiliani, David Angulo-Garcia, Rosa Cossar. Prominent in vivo influence of single interneurons in the developing barrel cortex. Nature neuroscience. vol 26. issue 9. 2023-08-31. PMID:37653166. |
using calcium imaging, connectivity analysis and holographic optical stimulation, we show that single gabaergic, but not glutamatergic, neurons influence population dynamics in the barrel cortex of non-anaesthetized mouse pups. |
2023-08-31 |
2023-09-07 |
mouse |
| b' Carmen Alonso-Mart\\xc3\\xadnez, Mario Rubio-Teves, C\\xc3\\xa9sar Porrero, Francisco Clasc\\xc3\\xa. Cerebellar and basal ganglia inputs define three main nuclei in the mouse ventral motor thalamus. Frontiers in neuroanatomy. vol 17. 2023-08-30. PMID:37645018.' |
immunolabeling for glutamatergic and gabaergic neurotransmission markers delineated two distinct main territories, characterized each by the presence of large vesicular glutamate transporter type 2 (vglut2) puncta or vesicular gaba transporter (vgat) puncta. |
2023-08-30 |
2023-09-07 |
mouse |
| David J Barker, Shiliang Zhang, Huiling Wang, David J Estrin, Jorge Miranda-Barrientos, Bing Liu, Rucha J Kulkarni, Junia Lara de Deus, Marisela Morale. Lateral preoptic area glutamate neurons relay nociceptive information to the ventral tegmental area. Cell reports. vol 42. issue 9. 2023-08-26. PMID:37632750. |
by ultrastructural quantitative synaptic analysis, ex vivo electrophysiology, and functional neuroanatomy we identify a complex circuitry between lpo glutamatergic and gabaergic neurons and vta dopaminergic, gabaergic, and glutamatergic neurons. |
2023-08-26 |
2023-09-07 |
Not clear |
| Hanyu Xi, Xingru Li, Yun Zhou, Yaojun Su. The Regulatory Effect of the Paraventricular Nucleus on Hypertension. Neuroendocrinology. 2023-08-20. PMID:37598678. |
in this article, we focus on the neuroendocrine mechanism, primarily exploring the specific contributions and interactions of various neurons and neuroendocrine hormones, including gabaergic, and glutamatergic neurons, nitric oxide, arginine vasopressin, oxytocin, and the renin-angiotensin system. |
2023-08-20 |
2023-09-07 |
human |
| Veronika Kondev, Mustafa Najeed, Niharika Loomba, Jordan Brown, Danny G Winder, Brad A Grueter, Sachin Pate. Synaptic and cellular endocannabinoid signaling mechanisms regulate stress-induced plasticity of nucleus accumbens somatostatin neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 34. 2023-08-17. PMID:37590414. |
here, we show that ecb signaling differentially regulates glutamatergic and feedforward gabaergic transmission onto nac somatostatin-expressing interneurons (nac |
2023-08-17 |
2023-09-07 |
Not clear |
| Xiaoping Hu, Jingdun Xie, Yilin Yang, Ziyi Qiu, Weicheng Lu, Xudong Lin, Bingzhe X. Multi-Target Neural Differentiation (MTND) Therapeutic Cocktail to Suppress Brain Tumor. International journal of molecular sciences. vol 24. issue 15. 2023-08-12. PMID:37569705. |
mtnd also induced strong expression of phenotypes associated with cell cycle exit/arrest and rapid neural reprograming from clinical glioma cells to glutamatergic and gabaergic expressing cells, which are two key neuronal types involved in many human brain functions, including learning and memory. |
2023-08-12 |
2023-08-16 |
human |
| Teresa M L Cramer, Berangere Pinan-Lucarre, Anna Cavaccini, Angeliki Damilou, Yuan-Chen Tsai, Musadiq A Bhat, Patrizia Panzanelli, Nicolas Rama, Patrick Mehlen, Dietmar Benke, Theofanis Karayannis, Jean-Louis Bessereau, Shiva K Tyagaraja. Adamtsl3 mediates DCC signaling to selectively promote GABAergic synapse function. Cell reports. vol 42. issue 8. 2023-08-12. PMID:37572323. |
we demonstrate that early post-natal deletion of adamtsl3 in neurons impairs dcc protein expression, causing reduced density of both glutamatergic and gabaergic synapses. |
2023-08-12 |
2023-08-16 |
Not clear |