| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andi H Hansen, Florian M Pauler, Michael Riedl, Carmen Streicher, Anna Heger, Susanne Laukoter, Christoph Sommer, Armel Nicolas, Björn Hof, Li Huei Tsai, Thomas Rülicke, Simon Hippenmeye. Tissue-Wide Effects Override Cell-Intrinsic Gene Function in Radial Neuron Migration. Oxford open neuroscience. vol 1. 2024-04-10. PMID:38596707. |
the mammalian neocortex is composed of diverse neuronal and glial cell classes that broadly arrange in six distinct laminae. |
2024-04-10 |
2024-04-12 |
Not clear |
| Ryan M Walsh, Raffaele Luongo, Elisa Giacomelli, Gabriele Ciceri, Chelsea Rittenhouse, Antonietta Verrillo, Maura Galimberti, Vittoria Dickinson Bocchi, Youjun Wu, Nan Xu, Simone Mosole, James Muller, Elena Vezzoli, Johannes Jungverdorben, Ting Zhou, Roger A Barker, Elena Cattaneo, Lorenz Studer, Arianna Baggiolin. Generation of human cerebral organoids with a structured outer subventricular zone. Cell reports. vol 43. issue 4. 2024-04-07. PMID:38583153. |
outer radial glia (org) emerge as cortical progenitor cells that support the development of an enlarged outer subventricular zone (osvz) and the expansion of the neocortex. |
2024-04-07 |
2024-04-10 |
human |
| Xin Yan, Xinqian Chen, Zhiying Shan, Lanrong B. Innovative Cyanine-Based Fluorescent Dye for Targeted Mitochondrial Imaging and Its Utility in Whole-Brain Visualization. ACS omega. vol 9. issue 2. 2024-01-22. PMID:38250363. |
based on the assessment of glial cell responses in the hippocampus and neocortex regions using gfap and iba1 biomarkers, cy5-peg2 seems to have minimal adverse effects on brain immune response or neuronal health. |
2024-01-22 |
2024-01-24 |
Not clear |
| Ryan Walsh, Elisa Giacomelli, Gabriele Ciceri, Chelsea Rittenhouse, Maura Galimberti, Youjun Wu, James Muller, Elena Vezzoli, Johannes Jungverdorben, Ting Zhou, Roger A Barker, Elena Cattaneo, Lorenz Studer, Arianna Baggiolin. Generation of human cerebral organoids with a structured outer subventricular zone. bioRxiv : the preprint server for biology. 2023-02-24. PMID:36824730. |
mammalian outer radial glia (org) emerge as cortical progenitor cells that directly support the development of an enlarged outer subventricular zone (osvz) and, in turn, the expansion of the neocortex. |
2023-02-24 |
2023-08-14 |
human |
| Samir Vaid, Oskari Heikinheimo, Takashi Namb. Embryonic mouse medial neocortex as a model system for studying the radial glial scaffold in fetal human neocortex. Journal of neural transmission (Vienna, Austria : 1996). 2022-11-30. PMID:36450874. |
first, basal (outer) radial glia (brg), which are the main cell type providing the radial scaffold to the migrating neurons in the fetal human neocortex, are very few in the mouse lateral neocortex, thus the radial glial scaffold is different from the fetal human neocortex. |
2022-11-30 |
2023-08-14 |
mouse |
| Lei Wang, Jun Young Park, Fengming Liu, Kris M Olesen, Shirui Hou, Jamy C Peng, Jordan Infield, Anna C Levesque, Yong-Dong Wang, Hongjian Jin, Yiping Fan, Patrick J Connelly, Shondra M Pruett-Miller, Miaofen G Hu, Philip W Hinds, Young-Goo Ha. A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 38. 2022-09-12. PMID:36095192. |
outer radial glia (orgs), npcs that are abundant in gyrencephalic species but rare in lissencephalic species, are thought to play key roles in the expansion and folding of the neocortex. |
2022-09-12 |
2023-08-14 |
mouse |
| Anneline Pinson, Lei Xing, Takashi Namba, Nereo Kalebic, Jula Peters, Christina Eugster Oegema, Sofia Traikov, Katrin Reppe, Stephan Riesenberg, Tomislav Maricic, Razvan Derihaci, Pauline Wimberger, Svante Pääbo, Wieland B Huttne. Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals. Science (New York, N.Y.). vol 377. issue 6611. 2022-09-08. PMID:36074851. |
using overexpression in developing mouse and ferret neocortex, knockout in fetal human neocortical tissue, and genome-edited cerebral organoids, we found that the modern human variant, htktl1, but not the neanderthal variant, increases the abundance of basal radial glia (brg) but not that of intermediate progenitors (bips). |
2022-09-08 |
2023-08-14 |
mouse |
| Simone Mader, Lior Brimberg, An Vo, Joshua J Strohl, James M Crawford, Alexandre Bonnin, Joseph Carrión, Delcora Campbell, Tomás S Huerta, Andrea La Bella, Roseann Berlin, Stephen L Dewey, Matthew Hellman, David Eidelberg, Irena Dujmovic, Jelena Drulovic, Jeffrey L Bennett, Bruce T Volpe, Patricio T Huerta, Betty Diamon. In utero exposure to maternal anti-aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring. Science translational medicine. vol 14. issue 641. 2022-04-20. PMID:35442708. |
we found that embryonic radial glia cells in neocortex express aqp4. |
2022-04-20 |
2023-08-13 |
mouse |
| Xiangbin Ruan, Gaoao Liu, Jiafeng Zhou, Pan Chen, Changjie Sun, Wei Liu, Chao Wu, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Pen. Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical Layers Formation in Developing Brain. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 9. 2021-11-30. PMID:33822906. |
here, we report that zbed3, which is a positive regulator of wnt/β-catenin signaling, colocalizes with β-catenin at the endfeet of radial glia in the ventricular zone of embryo mouse neocortex. |
2021-11-30 |
2023-08-13 |
mouse |
| Zhongfu Shen, Yang Lin, Jiajun Yang, David J Jörg, Yuwei Peng, Xiuli Zhang, Yifan Xu, Luisirene Hernandez, Jian Ma, Benjamin D Simons, Song-Hai Sh. Distinct progenitor behavior underlying neocortical gliogenesis related to tumorigenesis. Cell reports. vol 34. issue 11. 2021-10-22. PMID:33730566. |
radial glial progenitors (rgps) give rise to the vast majority of neurons and glia in the neocortex. |
2021-10-22 |
2023-08-13 |
mouse |
| Jiafeng Zhou, Gaoao Liu, Xiaoling Zhang, Chao Wu, Mengjie Ma, Jiarui Wu, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Pen. Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cerebral cortex (New York, N.Y. : 1991). 2021-09-22. PMID:34550336. |
meanwhile, we used the three cre lines to mediate dicer knockout and observed inconsistent phenotypes, including discrepancies in radial glial cell number, survival and neurogenesis in the neocortex and hippocampus. |
2021-09-22 |
2023-08-13 |
mouse |
| Zhen Li, William A Tyler, Ella Zeldich, Gabriel Santpere Baró, Mayumi Okamoto, Tianliuyun Gao, Mingfeng Li, Nenad Sestan, Tarik F Hayda. Transcriptional priming as a conserved mechanism of lineage diversification in the developing mouse and human neocortex. Science advances. vol 6. issue 45. 2021-09-18. PMID:33158872. |
using single-cell rna-sequencing and in vivo confirmation, we uncover previously unrecognized neural stem and progenitor cell diversity within the fetal mouse and human neocortex, including multiple types of radial glia and intermediate progenitors. |
2021-09-18 |
2023-08-13 |
mouse |
| Shirui Hou, Wan-Ling Ho, Lei Wang, Bryan Kuo, Jun Young Park, Young-Goo Ha. Biphasic Roles of Hedgehog Signaling in the Production and Self-Renewal of Outer Radial Glia in the Ferret Cerebral Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 10. 2021-09-15. PMID:34002221. |
the expansion of outer radial glia (orgs) and intermediate progenitor cells (ipcs) plays key roles in the expansion and consequential folding of the neocortex. |
2021-09-15 |
2023-08-13 |
mouse |
| Li He, Jennifer Jones, Weiguo He, Bryan C Bjork, Jiayu Wen, Qi Da. PRDM16 regulates a temporal transcriptional program to promote progression of cortical neural progenitors. Development (Cambridge, England). vol 148. issue 6. 2021-09-13. PMID:33597191. |
radial glia (rg) in the neocortex sequentially generate distinct subtypes of projection neurons, accounting for the diversity and complex assembly of cortical neural circuits. |
2021-09-13 |
2023-08-13 |
mouse |
| Jan A Kullmann, Sophie Meyer, Fabrizia Pipicelli, Christina Kyrousi, Felix Schneider, Nora Bartels, Silvia Cappello, Marco B Rus. Profilin1-Dependent F-Actin Assembly Controls Division of Apical Radial Glia and Neocortex Development. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 6. 2021-05-04. PMID:31867667. |
profilin1-dependent f-actin assembly controls division of apical radial glia and neocortex development. |
2021-05-04 |
2023-08-13 |
mouse |
| Jan A Kullmann, Sophie Meyer, Fabrizia Pipicelli, Christina Kyrousi, Felix Schneider, Nora Bartels, Silvia Cappello, Marco B Rus. Profilin1-Dependent F-Actin Assembly Controls Division of Apical Radial Glia and Neocortex Development. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 6. 2021-05-04. PMID:31867667. |
however, proliferative activity at basal positions was doubled in the mutant neocortex during mid-neurogenesis, with a drastic and specific increase in basal pax6+ cells indicative for elevated numbers of basal radial glia (brg). |
2021-05-04 |
2023-08-13 |
mouse |
| Caroline Alayne Pearson, Destaye M Moore, Haley O Tucker, Joseph D Dekker, Hui Hu, Amaya Miquelajáuregui, Bennett G Novitc. Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell reports. vol 30. issue 6. 2021-03-08. PMID:32049024. |
the laminar architecture of the mammalian neocortex depends on the orderly generation of distinct neuronal subtypes by apical radial glia (arg) during embryogenesis. |
2021-03-08 |
2023-08-13 |
mouse |
| Young-Goo Ha. Sonic hedgehog signaling: A conserved mechanism for the expansion of outer radial glia and intermediate progenitor cells and for the growth and folding of the neocortex. Neurogenesis (Austin, Tex.). vol 3. issue 1. 2020-09-30. PMID:28255571. |
sonic hedgehog signaling: a conserved mechanism for the expansion of outer radial glia and intermediate progenitor cells and for the growth and folding of the neocortex. |
2020-09-30 |
2023-08-13 |
mouse |
| Young-Goo Ha. Sonic hedgehog signaling: A conserved mechanism for the expansion of outer radial glia and intermediate progenitor cells and for the growth and folding of the neocortex. Neurogenesis (Austin, Tex.). vol 3. issue 1. 2020-09-30. PMID:28255571. |
the expansion of outer radial glia (orgs, also called basal rgs) and intermediate progenitor cells (ipcs) has played a key role in the evolutionary expansion and folding of the neocortex, resulting in superior sensorimotor and cognitive abilities. |
2020-09-30 |
2023-08-13 |
mouse |
| Lenin Veeraval, Conor J O'Leary, Helen M Coope. Adherens Junctions: Guardians of Cortical Development. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32117958. |
apical radial glia comprise the pseudostratified neuroepithelium lining the embryonic lateral ventricles and give rise to the extensive repertoire of pyramidal neuronal subtypes of the neocortex. |
2020-09-28 |
2023-08-13 |
Not clear |