| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicholas Fearns, Matias Wagner, Ingo Borggräfe, Mathias Kunz, Jan Rémi, Christian Vollma. Good Outcome of Resective Epilepsy Surgery in a One-Year-Old Child with Drug-Resistant Focal Epilepsy with a Novel Pathogenic COL4A1 Mutation. Neuropediatrics. 2024-01-03. PMID:38167978. |
pathogenic variants in col4a1, encoding the alpha chain of type iv collagen, have been associated with cerebrovascular pathology as well as malformations of cortical development, thereby causing structural epilepsy. |
2024-01-03 |
2024-01-06 |
Not clear |
| Irene Faiman, Rachel Sparks, Joel S Winston, Franz Brunnhuber, Naima Ciulini, Allan H Young, Paul Shotbol. Limited clinical validity of univariate resting-state EEG markers for classifying seizure disorders. Brain communications. vol 5. issue 6. 2023-12-19. PMID:38107505. |
study 1 is a hypothesis-driven study testing the ability of theta power and peak alpha frequency to classify people with epilepsy and people with psychogenic non-epileptic seizures, with an advanced machine learning pipeline. |
2023-12-19 |
2023-12-21 |
Not clear |
| Irene Faiman, Rachel Sparks, Joel S Winston, Franz Brunnhuber, Naima Ciulini, Allan H Young, Paul Shotbol. Limited clinical validity of univariate resting-state EEG markers for classifying seizure disorders. Brain communications. vol 5. issue 6. 2023-12-19. PMID:38107505. |
theta power and peak alpha frequency) have limited clinical validity for the classification of epilepsy and psychogenic non-epileptic seizures (mean accuracy: 48%). |
2023-12-19 |
2023-12-21 |
Not clear |
| Dominic M Dunstan, Mark P Richardson, Eugenio Abela, Ozgur E Akman, Marc Goodfello. Global nonlinear approach for mapping parameters of neural mass models. PLoS computational biology. vol 19. issue 3. 2023-03-24. PMID:36961869. |
we then use the moea to study differences in the alpha rhythm observed in eeg recorded from 20 people with epilepsy. |
2023-03-24 |
2023-08-14 |
Not clear |
| Susanna Pagni, Helena Martins Custodio, Adam Frankish, Jonathan M Mudge, James D Mills, Sanjay M Sisodiy. SCN1A: bioinformatically-informed revised boundaries for promoter and enhancer regions. Human molecular genetics. 2023-01-30. PMID:36715146. |
pathogenic variations in the sodium voltage-gated channel alpha subunit 1 (scn1a) gene are responsible for multiple epilepsy phenotypes, including dravet syndrome (ds), febrile seizures (fs), and genetic epilepsy with febrile seizures plus (gefs+). |
2023-01-30 |
2023-08-14 |
human |
| Esraa Ghazala, Doaa A Shahin, Yahya Wahb. Polymorphisms of the sodium voltage-gated channel, alpha subunit 1 (SCN1A -A3184G) gene among children with non-lesional epilepsy: a case-control study. Italian journal of pediatrics. vol 48. issue 1. 2022-09-02. PMID:36056404. |
polymorphisms of the sodium voltage-gated channel, alpha subunit 1 (scn1a -a3184g) gene among children with non-lesional epilepsy: a case-control study. |
2022-09-02 |
2023-08-14 |
Not clear |
| Esraa Ghazala, Doaa A Shahin, Yahya Wahb. Polymorphisms of the sodium voltage-gated channel, alpha subunit 1 (SCN1A -A3184G) gene among children with non-lesional epilepsy: a case-control study. Italian journal of pediatrics. vol 48. issue 1. 2022-09-02. PMID:36056404. |
mutations in the neuronal sodium voltage-gated channel, alpha subunit 1 (scn1a) gene have been associated with epilepsy. |
2022-09-02 |
2023-08-14 |
Not clear |
| Hussein A Algahtani, Bader H Shirah, Ahmed Samman, Abdulellah Alhazm. Epilepsy and Hearing Loss in a Patient with a Rare Heterozygous Variant in the Journal of epilepsy research. vol 12. issue 1. 2022-08-01. PMID:35910327. |
epilepsy and hearing loss in a patient with a rare heterozygous variant in the the calcium voltage-gated channel subunit alpha 1 h ( |
2022-08-01 |
2023-08-14 |
Not clear |
| Hamidreza Zalpoor, Abdullatif Akbari, Mohsen Nabi-Afjadi, Razieh Forghaniesfidvajani, Chanour Tavakol, Zohreh Barzegar, Farideh Iravanpour, Mahshid Hosseini, Seyed Reza Mousavi, Majid Reza Farrokh. Hypoxia-inducible factor 1 alpha (HIF-1α) stimulated and P2X7 receptor activated by COVID-19, as a potential therapeutic target and risk factor for epilepsy. Human cell. 2022-07-13. PMID:35831562. |
hypoxia-inducible factor 1 alpha (hif-1α) stimulated and p2x7 receptor activated by covid-19, as a potential therapeutic target and risk factor for epilepsy. |
2022-07-13 |
2023-08-14 |
Not clear |
| Rui Ma, Yiran Duan, Liping Zhang, Xiaohong Qi, Lu Zhang, Sipei Pan, Lehong Gao, Chaodong Wang, Yuping Wan. Frontiers in molecular neuroscience. vol 15. 2022-06-06. PMID:35663268. |
to expand the genotypes and phenotypes of sodium voltage-gated channel alpha subunit 1 (scn1a)-related epilepsy. |
2022-06-06 |
2023-08-14 |
Not clear |
| R Albaradie, D N Baig, S Bashi. Sodium voltage-gated channel alpha subunit 9 mutation in epilepsy. European review for medical and pharmacological sciences. vol 25. issue 24. 2022-01-04. PMID:34982449. |
sodium voltage-gated channel alpha subunit 9 mutation in epilepsy. |
2022-01-04 |
2023-08-13 |
Not clear |
| Wei Shan, Xiaoling Yang, Qian Ren, Qun Wan. Generation of SCN1A Knock out induced pluripotent stem cell (iPSC) line. Stem cell research. vol 55. 2021-10-26. PMID:34247112. |
the scn1a gene encodes the voltage-gated na+ channel alpha subunit nav1.1 and is the most clinically relevant epilepsy gene. |
2021-10-26 |
2023-08-13 |
human |
| Masahiro Kanatani, Tadashi Adachi, Ryoichi Sakata, Yoko Nishimura, Yoshiaki Saito, Yoshihiro Maegaki, Yasuhiro Watanabe, Ritsuko Hanajim. Dravet syndrome with parkinsonian symptoms and intact dopaminergic neurons: A case report. Brain & development. vol 43. issue 3. 2021-10-04. PMID:33199159. |
dravet syndrome (ds) is severe myoclonic epilepsy in infancy and associated with a heterozygous mutation of the gene for the sodium channel alpha 1 subunit (scn1a). |
2021-10-04 |
2023-08-13 |
Not clear |
| Ruiqing Yang, Ruiyi Qian, Kerun Chen, Wei Yi, Xiutian Sim. Genetic polymorphisms in SCN2A are not associated with epilepsy risk and AEDs response: evidence from a meta-analysis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 7. 2021-07-09. PMID:33914194. |
previous studies have investigated the association between rs2304016 and rs17183814 polymorphisms in sodium voltage-gated channel alpha subunit 2 (scn2a) and epilepsy risk and responsiveness to antiepileptic drugs (aeds) but with conflicting results. |
2021-07-09 |
2023-08-13 |
Not clear |
| Dilara Mermi Dibek, Cavid Baba, Nurcan Akbulut, Pınar Tamer Çoban, İbrahim Öztura, Barış Bakla. Rare Two Findings in Frontal Lobe Epilepsy: Finger Snapping, and Ictal Alpha Activity. Annals of Indian Academy of Neurology. vol 24. issue 2. 2021-07-06. PMID:34220080. |
rare two findings in frontal lobe epilepsy: finger snapping, and ictal alpha activity. |
2021-07-06 |
2023-08-13 |
Not clear |
| Yun Qin, Nan Zhang, Yan Chen, Yue Tan, Li Dong, Peng Xu, Daqing Guo, Tao Zhang, Dezhong Yao, Cheng Lu. How Alpha Rhythm Spatiotemporally Acts Upon the Thalamus-Default Mode Circuit in Idiopathic Generalized Epilepsy. IEEE transactions on bio-medical engineering. vol 68. issue 4. 2021-06-25. PMID:32976091. |
the purpose of this study is to investigate how the ongoing alpha oscillation acts upon the local temporal dynamics and spatial hyperconnectivity in epilepsy. |
2021-06-25 |
2023-08-13 |
Not clear |
| Yogatheesan Varatharajah, Brent Berry, Boney Joseph, Irena Balzekas, Tal Pal Attia, Vaclav Kremen, Benjamin Brinkmann, Ravishankar Iyer, Gregory Worrel. Characterizing the electrophysiological abnormalities in visually reviewed normal EEGs of drug-resistant focal epilepsy patients. Brain communications. vol 3. issue 2. 2021-06-17. PMID:34131643. |
we found that the fraction of alpha power is generally reduced (i) in drug-resistant focal epilepsy compared to healthy controls, and (ii) in right-handed drug-resistant focal epilepsy subjects with left hemispheric seizures compared to those with right hemispheric seizures, and that the differences are most prominent in the frontal and temporal regions. |
2021-06-17 |
2023-08-13 |
human |
| Yogatheesan Varatharajah, Brent Berry, Boney Joseph, Irena Balzekas, Tal Pal Attia, Vaclav Kremen, Benjamin Brinkmann, Ravishankar Iyer, Gregory Worrel. Characterizing the electrophysiological abnormalities in visually reviewed normal EEGs of drug-resistant focal epilepsy patients. Brain communications. vol 3. issue 2. 2021-06-17. PMID:34131643. |
the fraction of alpha power yielded area under curve values of 0.83 in distinguishing drug-resistant focal epilepsy from healthy and 0.77 in identifying the epileptic hemisphere in drug-resistant focal epilepsy patients. |
2021-06-17 |
2023-08-13 |
human |
| Yogatheesan Varatharajah, Brent Berry, Boney Joseph, Irena Balzekas, Tal Pal Attia, Vaclav Kremen, Benjamin Brinkmann, Ravishankar Iyer, Gregory Worrel. Characterizing the electrophysiological abnormalities in visually reviewed normal EEGs of drug-resistant focal epilepsy patients. Brain communications. vol 3. issue 2. 2021-06-17. PMID:34131643. |
our findings support that eeg-based measures of normal brain function, such as the normalized spectral power of alpha activity, may help identify patients with epilepsy even when an eeg does not contain any epileptiform activity, recorded seizures or other abnormalities. |
2021-06-17 |
2023-08-13 |
human |
| Yogatheesan Varatharajah, Brent Berry, Boney Joseph, Irena Balzekas, Tal Pal Attia, Vaclav Kremen, Benjamin Brinkmann, Ravishankar Iyer, Gregory Worrel. Characterizing the electrophysiological abnormalities in visually reviewed normal EEGs of drug-resistant focal epilepsy patients. Brain communications. vol 3. issue 2. 2021-06-17. PMID:34131643. |
although alpha abnormalities are unlikely to be disease-specific, we propose that such abnormalities may provide a higher pre-test probability for epilepsy when an individual being screened for epilepsy has a normal eeg on visual assessment. |
2021-06-17 |
2023-08-13 |
human |