| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy Trongnetrpunya, Bijurika Nandi, Daesung Kang, Bernat Kocsis, Charles E Schroeder, Mingzhou Din. Assessing Granger Causality in Electrophysiological Data: Removing the Adverse Effects of Common Signals via Bipolar Derivations. Frontiers in systems neuroscience. vol 9. 2016-02-02. PMID:26834583. |
this was followed by analyzing data from three experimental preparations where a priori predictions regarding the patterns of causal interactions can be made: (1) laminar recordings from the hippocampus of an anesthetized rat during theta rhythm, (2) laminar recordings from v4 of an awake-behaving macaque monkey during alpha rhythm, and (3) ecog recordings from electrode arrays implanted in the middle temporal lobe and prefrontal cortex of an epilepsy patient during fixation. |
2016-02-02 |
2023-08-13 |
rat |
| Sarah Vergult, Annelies Dheedene, Alfred Meurs, Fran Faes, Bertrand Isidor, Sandra Janssens, Agnès Gautier, Cédric Le Caignec, Björn Mente. Genomic aberrations of the CACNA2D1 gene in three patients with epilepsy and intellectual disability. European journal of human genetics : EJHG. vol 23. issue 5. 2016-01-06. PMID:25074461. |
aberrations affecting genes encoding the alpha subunit of these channels have been associated with epilepsy and neuropsychiatric disorders such as autism or schizophrenia. |
2016-01-06 |
2023-08-13 |
Not clear |
| Weijing Kong, Yujia Zhang, Yang Gao, Xiaoyan Liu, Kai Gao, Han Xie, Jingmin Wang, Ye Wu, Yuehua Zhang, Xiru Wu, Yuwu Jian. SCN8A mutations in Chinese children with early onset epilepsy and intellectual disability. Epilepsia. vol 56. issue 3. 2015-05-11. PMID:25785782. |
mutations in scn8a, a voltage-gated sodium-channel type viii alpha subunit gene, have recently been recognized as one of the pathogenic mechanisms leading to epilepsy and intellectual/developmental disabilities (idds). |
2015-05-11 |
2023-08-13 |
Not clear |
| Apostolos Papandreou, Martin M Tisdall, W K Chong, J Helen Cross, William F Harkness, Sophia M Varadka. COL4A1 mutations should not be a contraindication for epilepsy surgery. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery. vol 30. issue 8. 2015-03-09. PMID:24864020. |
we describe the first case in the literature of complication-free epilepsy surgery in a paediatric patient with collagen type iv alpha 1 (col4a1) mutation. |
2015-03-09 |
2023-08-13 |
Not clear |
| Jiao Jiao, Yuanyuan Yang, Yiwu Shi, Jiayu Chen, Rui Gao, Yong Fan, Hui Yao, Weiping Liao, Xiao-Fang Sun, Shaorong Ga. Modeling Dravet syndrome using induced pluripotent stem cells (iPSCs) and directly converted neurons. Human molecular genetics. vol 22. issue 21. 2014-04-30. PMID:23773995. |
severe myoclonic epilepsy of infancy (smei, also known as dravet syndrome) and genetic epilepsy with febrile seizures plus (mild febrile seizures) can both arise due to mutations of scn1a, the gene encoding alpha 1 pore-forming subunit of the nav1.1 voltage-gated sodium channel. |
2014-04-30 |
2023-08-12 |
Not clear |
| Katja Menzler, Anke Hermsen, Katharina Balkenhol, Caroline Duddek, Hannes Bugiel, Sebastian Bauer, Stephanie Schorge, Philipp S Reif, Karl Martin Klein, Anja Haag, Wolfgang H Oertel, Hajo M Hamer, Susanne Knake, Holger Trucks, Thomas Sander, Felix Roseno. A common SCN1A splice-site polymorphism modifies the effect of carbamazepine on cortical excitability--a pharmacogenetic transcranial magnetic stimulation study. Epilepsia. vol 55. issue 2. 2014-04-07. PMID:24417206. |
scn1a encodes the alpha subunit of the voltage-gated sodium channel and plays a crucial role in several epilepsy syndromes. |
2014-04-07 |
2023-08-12 |
Not clear |
| Fabrizio Vecchio, Mario Tombini, Paola Buffo, Giovanni Assenza, Giovanni Pellegrino, Antonella Benvenga, Claudio Babiloni, Paolo Maria Rossin. Mobile phone emission increases inter-hemispheric functional coupling of electroencephalographic α rhythms in epileptic patients. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 84. issue 2. 2013-02-11. PMID:22326594. |
if confirmed by future studies on a larger group of epilepsy patients, the modulation of the inter-hemispheric alpha coherence due to the gsm-emfs could have clinical implications and be related to changes in cognitive-motor function. |
2013-02-11 |
2023-08-12 |
human |
| Silke Appenzeller, Ingo Helbig, Ulrich Stephani, Martin Häusler, Gerhard Kluger, May Bungeroth, Stefanie Müller, Gregor Kuhlenbäumer, Andreas van Baale. Febrile infection-related epilepsy syndrome (FIRES) is not caused by SCN1A, POLG, PCDH19 mutations or rare copy number variations. Developmental medicine and child neurology. vol 54. issue 12. 2013-02-07. PMID:23066759. |
fires shares several phenotypic features with epilepsies seen in patients with protocadherin 19 (pcdh19), sodium channel protein type 1 subunit alpha (scn1a), and dna polymerase subunit gamma-1 (polg) mutations. |
2013-02-07 |
2023-08-12 |
Not clear |
| Caroline K Mbuba, Amina Abubakar, Sally Hartley, Peter Odermatt, Charles R Newton, Julie A Carte. Development and validation of the Kilifi Epilepsy Beliefs and Attitude Scale. Epilepsy & behavior : E&B. vol 24. issue 4. 2012-12-20. PMID:22795174. |
a final scale of 34 items had cronbach's alpha scores for the five subscales: causes of epilepsy (α=0.71); biomedical treatment of epilepsy (α=0.70); cultural treatment of epilepsy (α=0.75); risk and safety concerns about epilepsy (α=0.56); and negative attitudes about epilepsy (α=0.76) and entire scale (α=0.70). |
2012-12-20 |
2023-08-12 |
Not clear |
| Pål G Larsson, Orvar Eeg-Olofsson, Göran Lant. Alpha frequency estimation in patients with epilepsy. Clinical EEG and neuroscience. vol 43. issue 2. 2012-09-20. PMID:22715482. |
alpha frequency estimation in patients with epilepsy. |
2012-09-20 |
2023-08-12 |
Not clear |
| Aristea S Galanopoulou, Jan A Gorter, Carlos Ceped. Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target. Epilepsia. vol 53. issue 7. 2012-09-14. PMID:22578218. |
these include tuberous sclerosis, which is due to mutations in tsc1 or tsc2 genes; mutations in phosphatase and tensin homolog (pten) as in cowden syndrome, polyhydramnios, megalencephaly, symptomatic epilepsy syndrome (pmse) due to mutations in the ste20-related kinase adaptor alpha (stradalpha); and neurofibromatosis type 1 attributed to neurofibromin 1 mutations. |
2012-09-14 |
2023-08-12 |
mouse |
| L Michels, K Bucher, S Brem, P Halder, R Lüchinger, M Liechti, E Martin, D Jeanmonod, J Kröll, D Brandei. Does greater low frequency EEG activity in normal immaturity and in children with epilepsy arise in the same neuronal network? Brain topography. vol 24. issue 1. 2011-12-12. PMID:20820898. |
spectral analysis revealed that global low (delta: 1-3 hz, theta: 4-7 hz), medium (alpha: 8-12 hz) and high (beta: 13-25 hz) frequency eeg activity was greater in children without epilepsy compared to adults, and even further elevated for children with epilepsy. |
2011-12-12 |
2023-08-12 |
Not clear |
| Richard E Fry. Leber's hereditary optic neuropathy mutations associated with infantile-onset myoclonic epilepsy. Journal of child neurology. vol 26. issue 6. 2011-09-19. PMID:21527392. |
dravet's severe myoclonic epilepsy in infancy is especially interesting as it is associated with fever-provoked seizures and mutations in the alpha subunit of the sodium channel (scn1a) in about one-third of the cases. |
2011-09-19 |
2023-08-12 |
Not clear |
| David Sherman, Ning Zhang, Shikha Garg, Nitish V Thakor, Marek A Mirski, Mirinda Anderson White, Melvin J Hinic. Detection of nonlinear interactions of EEG alpha waves in the brain by a new coherence measure and its application to epilepsy and anti-epileptic drug therapy. International journal of neural systems. vol 21. issue 2. 2011-07-14. PMID:21442775. |
detection of nonlinear interactions of eeg alpha waves in the brain by a new coherence measure and its application to epilepsy and anti-epileptic drug therapy. |
2011-07-14 |
2023-08-12 |
rat |
| Shan Tang, Jean Pierre Lin, Elaine Hughes, Ata Siddiqui, Ming Lim, Karine Lascelle. Encephalopathy and SCN1A mutations. Epilepsia. vol 52. issue 4. 2011-06-01. PMID:21426328. |
we describe three children with genetically different sodium channel alpha 1 subunit (scn1a) mutation associated epilepsy who experienced a sudden and sustained neurologic regression following status epilepticus in two and acute sepsis in one. |
2011-06-01 |
2023-08-12 |
Not clear |
| Mei-Juan Yu, Yi-Wu Shi, Mei-Mei Gao, Wei-Yi Deng, Xiao-Rong Liu, Li Chen, Yue-Sheng Long, Yong-Hong Yi, Wei-Ping Lia. Milder phenotype with SCN1A truncation mutation other than SMEI. Seizure. vol 19. issue 7. 2010-12-02. PMID:20630778. |
till now truncation mutations of voltage-gated sodium channel alpha subunit type i (scn1a) gene were mostly found in severe myoclonic epilepsy of infancy (smei) patients. |
2010-12-02 |
2023-08-12 |
Not clear |
| Paul J Fitzgeral. Is elevated norepinephrine an etiological factor in some cases of epilepsy? Seizure. vol 19. issue 6. 2010-10-19. PMID:20493725. |
in assessing the elevated ne epilepsy hypothesis, the following seven lines of evidence are examined that include studies of: (1) antidepressants that raise the level of ne; (2) clonidine and other alpha 2 adrenergic agonist drugs that lower the level of ne; (3) prazosin and other drugs that affect alpha adrenoceptors; (4) propranolol and other drugs that affect beta adrenoceptors; (5) pheochromocytoma, which is a rare cancer of the adrenal glands that can boost ne levels; (6) comorbidity of epilepsy with bipolar disorder, hypertension, and obesity, where all four conditions may involve elevated ne; and (7) psychological stress, which is associated with increased release of ne. |
2010-10-19 |
2023-08-12 |
Not clear |
| Ritu Kumari, Ram Lakhan, J Kalita, U K Misra, Balraj Mitta. Association of alpha subunit of GABAA receptor subtype gene polymorphisms with epilepsy susceptibility and drug resistance in north Indian population. Seizure. vol 19. issue 4. 2010-07-09. PMID:20356767. |
association of alpha subunit of gabaa receptor subtype gene polymorphisms with epilepsy susceptibility and drug resistance in north indian population. |
2010-07-09 |
2023-08-12 |
human |
| Chang-zheng Li, Wei Xie, Yong Bao, Ye Zho. [Effect of saikosaponin alpha on experimental epilepsy in rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 27. issue 6. 2010-06-10. PMID:17584653. |
[effect of saikosaponin alpha on experimental epilepsy in rats]. |
2010-06-10 |
2023-08-12 |
rat |
| Chang-zheng Li, Wei Xie, Yong Bao, Ye Zho. [Effect of saikosaponin alpha on experimental epilepsy in rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 27. issue 6. 2010-06-10. PMID:17584653. |
to investigate the effect of saikosaponin alpha (ssalpha) on experimental epilepsy in rats. |
2010-06-10 |
2023-08-12 |
rat |