| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V L Silveira, E A Limão. Participation of alpha 2-macroglobulin in counter-irritation. Agents and actions. vol 36. issue 3-4. 1992-10-22. PMID:1382380. |
however, when adrenalectomy was done 20 h after the first stimulus, allowing the synthesis of large amounts of alpha 2-m, the carrageenin stimulus again produced ci. |
1992-10-22 |
2023-08-11 |
rat |
| V L Silveira, E A Limão. Participation of alpha 2-macroglobulin in counter-irritation. Agents and actions. vol 36. issue 3-4. 1992-10-22. PMID:1382380. |
nevertheless, the anti-inflammatory factors involved in ci were, in fact, corticosteroid-dependent and alpha 2-m was probably one of the main factors. |
1992-10-22 |
2023-08-11 |
rat |
| R F Schafers, H L Elliott, P A Meredith, S H Miller, J L Rei. Studies with abanoquil (UK-52,046) a novel quinoline alpha 1-adrenoceptor antagonist: II. Duration of action, pharmacokinetics and concentration-effect relationships in normotensive subjects. British journal of clinical pharmacology. vol 32. issue 5. 1991-12-30. PMID:1683250. |
2. alpha 1-adrenoceptor antagonism (as assessed by phenylephrine pressor responses) was detectable for up to 12 h post dosing: at 12 h there was a significant 1.5-fold rightward shift (95% ci: 2.2 to 1.1) of the pressor dose-response curve for diastolic blood pressure. |
1991-12-30 |
2023-08-11 |
human |
| M Castroviejo, M T Gatius, S Litva. A low molecular weight DNA polymerase from wheat embryos. Plant molecular biology. vol 15. issue 3. 1991-10-09. PMID:2103459. |
polyclonal antibodies raised in rabbits against dna polymerase ci did not inhibit animal dna polymerases alpha and beta or wheat dna polymerase a, whereas wheat dna polymerases cii and b were much less affected than the ci enzyme. |
1991-10-09 |
2023-08-11 |
Not clear |
| V S Chauhan, K Uma, P Kaur, P Balara. Conformations of dehydrophenylalanine containing peptides: nmr studies of an acyclic hexapeptide with two delta Z-Phe residues. Biopolymers. vol 28. issue 3. 1989-05-26. PMID:2706313. |
evidence is also obtained for conformational heterogeneity from the detection of some ci alpha h----ni + 1h noes characteristic of extended strands. |
1989-05-26 |
2023-08-11 |
Not clear |
| V S Chauhan, K Uma, P Kaur, P Balara. Conformations of dehydrophenylalanine containing peptides: nmr studies of an acyclic hexapeptide with two delta Z-Phe residues. Biopolymers. vol 28. issue 3. 1989-05-26. PMID:2706313. |
in (cd3)2so, the peptide largely favors an extended conformation, characterized by five solvent-exposed nh groups and successive ci alpha h----ni + 1h noes for the l-residues and ci beta h----ni + 1h noes for the delta z-phe residues. |
1989-05-26 |
2023-08-11 |
Not clear |
| K Uma, V S Chauhan, A Kumar, P Balara. Conformations of dehydrophenylalanine containing peptides. Nuclear Overhauser effect study of two acyclic tetrapeptides. International journal of peptide and protein research. vol 31. issue 4. 1988-08-18. PMID:3391742. |
studies establish the occurrence of several diagnostic inter-residue n.o.e.s (ci alpha h----ni+1h and nih----ni+1h) between backbone protons. |
1988-08-18 |
2023-08-11 |
Not clear |
| G Dehó, S Zangrossi, D Ghisotti, G Siron. Alternative promoters in the development of bacteriophage plasmid P4. Journal of virology. vol 62. issue 5. 1988-05-26. PMID:2833620. |
the early postinfection phase is characterized by the leftward transcription of an operon including the genes ci (p4 immunity) and alpha (replication). |
1988-05-26 |
2023-08-11 |
Not clear |
| A M Aitokallio-Tallberg, L U Viinikka, R O Ylikorkal. Increased synthesis of prostacyclin and thromboxane in human ovarian malignancy. Cancer research. vol 48. issue 9. 1988-05-18. PMID:3281748. |
healthy ovary (n = 10) produced both 6-keto-pgf1 alpha [mean, 8.9; 95% confidence interval (ci) from 5.4 to 15.2 ng/mg protein/min] and txb2 (mean, 1.9 ng/mg protein/min; 95% ci from 1.0 to 3.7 ng/mg protein/min). |
1988-05-18 |
2023-08-11 |
human |
| A M Aitokallio-Tallberg, L U Viinikka, R O Ylikorkal. Increased synthesis of prostacyclin and thromboxane in human ovarian malignancy. Cancer research. vol 48. issue 9. 1988-05-18. PMID:3281748. |
the production of 6-keto-pgf1 alpha (mean, 12.2; 95% ci from 7.7 to 19.3 ng/mg protein/min) and that of txb2 (mean, 4.8; 95% ci from 2.1 to 11.9 ng/mg protein/min) by benign cystic tumors (n = 12) was normal. |
1988-05-18 |
2023-08-11 |
human |
| A M Aitokallio-Tallberg, L U Viinikka, R O Ylikorkal. Increased synthesis of prostacyclin and thromboxane in human ovarian malignancy. Cancer research. vol 48. issue 9. 1988-05-18. PMID:3281748. |
ovarian anaplastic cancer and adenocarcinoma (n = 12) produced 6-keto-pgf1 alpha on average 11.6-fold (95% ci from 5.2 to 26.0) 6-keto-pgf1 alpha and txb2 on average 30.0-fold (95% ci from 13.5 to 66.7) over production by healthy ovaries, and the ratio of 6-keto-pgf1 alpha to txb2 shifted to the dominance of txb2. |
1988-05-18 |
2023-08-11 |
human |
| D C Spencer, N L Pienaar, P M Atkinso. Disturbances of blood coagulation associated with Salmonella typhi infections. The Journal of infection. vol 16. issue 2. 1988-05-12. PMID:3351316. |
estimations of prothrombin time, activated partial thromboplastin time, fibrinogen, fibrin degradation products (fdps), factors vii, viii and xii, alpha i antitrypsin, plasminogen, ci esterase inhibitor, and platelet counts were performed as well as liver function tests and blood counts. |
1988-05-12 |
2023-08-11 |
Not clear |
| E Shapiro, H Lepo. Alpha 1 adrenergic receptors in canine lower genitourinary tissues: insight into development and function. The Journal of urology. vol 138. issue 4 Pt 2. 1987-11-03. PMID:2821295. |
saturation experiments were performed in tissue homogenates using [125iodine]-heat, an alpha 1-adrenergic antagonist of high specific activity (2,200 ci. |
1987-11-03 |
2023-08-11 |
dog |
| P J Rice, A Hamada, D D Miller, P N Pati. Asymmetric catecholimidazolines and catecholamidines: affinity and efficacy relationships at the alpha adrenoreceptor in rat aorta. The Journal of pharmacology and experimental therapeutics. vol 242. issue 1. 1987-08-31. PMID:3039106. |
thus, the easson-stedman model cannot be extended to either the ci or ca series of alpha adrenoreceptor agonists. |
1987-08-31 |
2023-08-11 |
rat |
| C H Ahn, A Hamada, D D Miller, D R Felle. Alpha-adrenoceptor-mediated actions of optical isomers and desoxy analogs of catecholimidazoline and norepinephrine in human platelets: in vitro. Biochemical pharmacology. vol 35. issue 22. 1986-12-18. PMID:3022751. |
these results suggest that the enantiomers and desoxy derivatives of ci and ne mediate their effects in human platelets by an interaction with alpha-adrenoceptors; catecholamines and imidazolines interact with the same alpha-adrenoceptors in human platelets; the stereochemical requirements of both chemical classes for stimulatory activity in human platelets adhere to the easson-stedman hypothesis in this alpha 2-adrenoceptor system; and desoxy-ci possessed the highest potency as an antagonist of alpha-adrenoceptors which suggests that the hydroxy group at the benzylic carbon atom of these imidazolines may not be required for maximal binding to adrenoceptors in platelets. |
1986-12-18 |
2023-08-11 |
human |
| T M Schetgens, G Bakkeren, C van Dun, J G Hontelez, R C van den Bos, A van Kamme. Molecular cloning and functional characterization of Rhizobium leguminosarum structural nif-genes by site-directed transposon mutagenesis and expression in Escherichia coli minicells. Journal of molecular and applied genetics. vol 2. issue 4. 1984-07-31. PMID:6330264. |
the localization of tn5 insertion sites was in accordance with observed consequences: two genotypically different tn5-induced mutations within nif d caused repression of ci alpha and beta synthesis and a strong reduction of cii production, thus resulting in a fix- phenotype. |
1984-07-31 |
2023-08-12 |
Not clear |
| C F Scott, D Sinha, F S Seaman, P N Walsh, R W Colma. Amidolytic assay of human factor XI in plasma: comparison with a coagulant assay and a new rapid radioimmunoassay. Blood. vol 63. issue 1. 1984-02-14. PMID:6606454. |
after inactivation of alpha 1-antitrypsin, ci inhibitor, and other plasma protease inhibitors with chci3, plasma was incubated with kaolin, in the absence of added calcium, which limited the enzymes formed to those dependent on contact activation. |
1984-02-14 |
2023-08-12 |
human |
| J Sengupta, B C Paria, S K Manchand. Effect of an estrogen antagonist on development of blastocysts and implantation in the hamster. The Journal of experimental zoology. vol 225. issue 1. 1983-05-05. PMID:6339672. |
the effects of the drug could be reversed by estradiol-17b (1 microgram) but not estradiol-17 alpha (1 microgram) injected intraluminally with ci 628 citrate. |
1983-05-05 |
2023-08-12 |
Not clear |
| J A Katzenellenbogen, K D McElvany, S G Senderoff, K E Carlson, S W Landvatter, M J Welc. 16 alpha-[77Br]bromo-11 beta-methoxyestradiol-17 beta: a gamma-emitting estrogen imaging agent with high uptake and retention by target organs. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 23. issue 5. 1982-07-19. PMID:7077395. |
16 alpha[77br]bromo-11 beta-methoxyestradiol-17 beta [mbe(br-77)], a compound with high affinity for the estrogen receptor and with low nonspecific binding, has been prepared with an effective specific activity of 770--1450 ci per mmole at the time of synthesis. |
1982-07-19 |
2023-08-12 |
human |
| S C Rastogi, J Clausen, T Fo. Abnormal serum alpha 2-macroglobulin in multiple sclerosis. European neurology. vol 20. issue 1. 1981-05-21. PMID:6162641. |
crossed immunoelectrophoresis (ci) of serum alpha 2-macroglobulin (alpha 2-m) of neurological patients revealed that alpha 2-m in serum of multiple sclerosis (ms) patients was abnormal. |
1981-05-21 |
2023-08-12 |
Not clear |