| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P J Shen, A L Gundlac. Differential modulatory effects of alpha- and beta-adrenoceptor agonists and antagonists on cortical immediate-early gene expression following focal cerebrocortical lesion-induced spreading depression. Brain research. Molecular brain research. vol 83. issue 1-2. 2001-02-15. PMID:11072104. |
these results confirm that alpha(1)- and beta-ars normally mediate a stimulatory, and alpha(2)-ars a net inhibitory, influence on cortical cell activity (reflected by ngfi-a, c-fos expression); and demonstrate that alterations in noradrenergic tone modulate the level of cellular activation during and after sd, which is primarily elicited by k(+)/glutamate via nmda receptors and ca(2+)-associated mechanisms. |
2001-02-15 |
2023-08-12 |
rat |
| H Liu, J E Cunnick, S Hendric. Opposing effects of prostaglandin E(2)and F(2 alpha) on rat liver-associated natural killer cell activity in vitro. Prostaglandins, leukotrienes, and essential fatty acids. vol 63. issue 3. 2000-12-07. PMID:10991773. |
as potential cancer-associated immunological regulators, the concentrations of hepatic prostaglandins e(2)(pge(2 alpha)and f(2 alpha)(pgf(2 alpha)) were compared in 9-week-old male and female f344/n and sprague-dawley (sd) rats. |
2000-12-07 |
2023-08-12 |
rat |
| H Liu, J E Cunnick, S Hendric. Opposing effects of prostaglandin E(2)and F(2 alpha) on rat liver-associated natural killer cell activity in vitro. Prostaglandins, leukotrienes, and essential fatty acids. vol 63. issue 3. 2000-12-07. PMID:10991773. |
in contrast, 50 ng pgf(2 alpha)/ml and 100 ng pgf(2 alpha)/ml significantly stimulated hepatic nk activity compared with untreated hepatic cells from both f344/n and sd rats. |
2000-12-07 |
2023-08-12 |
rat |
| U Isoglu-Alkaç, C Basar-Eroglu, A Ademoglu, T Demiralp, M Miener, M Stadle. Alpha activity decreases during the perception of Necker cube reversals: an application of wavelet transform. Biological cybernetics. vol 82. issue 4. 2000-06-30. PMID:10804063. |
the rms values of the alpha frequency band were measured for two time periods: +/- 3 sd around the mean peak latency of the perceptual-reversal-related positivity and a time window of the same length before the positive wave. |
2000-06-30 |
2023-08-12 |
human |
| E E Eriksson, J Werr, Y Guo, P Thoren, L Lindbo. Direct observations in vivo on the role of endothelial selectins and alpha(4) integrin in cytokine-induced leukocyte-endothelium interactions in the mouse aorta. Circulation research. vol 86. issue 5. 2000-04-14. PMID:10720414. |
leukocyte rolling was almost abolished by an antibody blocking the function of p-selectin, whereas function-blocking antibodies against e-selectin and the alpha(4)-integrin subunit decreased rolling leukocyte flux to 51+/-34% (mean +/- sd) and 59+/-11% of the value before antibody treatment, respectively. |
2000-04-14 |
2023-08-12 |
mouse |
| C C Love, R M Kenne. The relationship of increased susceptibility of sperm DNA to denaturation and fertility in the stallion. Theriogenology. vol 50. issue 6. 2000-04-07. PMID:10734467. |
the scsa measures, mean of alpha-t (mean alpha t), standard deviation of alpha-t (sd alpha t), and the comp of alpha-t (cells outside the main population)] were significantly correlated with the percentage seasonal pregnancy rate (spr; mean alpha t, r = -0.24, p < or = 0.05; % comp alpha t, r = -0.27, p < or = 0.05); percentage pregnant per first cycle (fcp; sd alpha t, r = -0.30, p < or = 0.01; % comp alpha t, r = -0.42, p < or = 0.0001); and the percentage pregnant per cycle (pc; mean alpha t, r = -0.31, p < or = 0.01; sd alpha t, r = -0.32, p < or = 0.01; % comp alpha t, r = -0.41, p < or = 0.0001). |
2000-04-07 |
2023-08-12 |
Not clear |
| J Werr, J Johansson, E E Eriksson, P Hedqvist, E Ruoslahti, L Lindbo. Integrin alpha(2)beta(1) (VLA-2) is a principal receptor used by neutrophils for locomotion in extravascular tissue. Blood. vol 95. issue 5. 2000-03-29. PMID:10688841. |
local administration of function-blocking monoclonal antibody or peptide recognizing the alpha(2)beta(1) integrin reduced pmn migration velocity in the extravascular tissue by 73% +/- 3% and 70% +/- 10%, respectively (means +/- sd). |
2000-03-29 |
2023-08-12 |
mouse |
| C R Bonapace, R L White, L V Friedrich, E D Norcross, J A Boss. Pharmacokinetics of cefepime in patients with thermal burn injury. Antimicrobial agents and chemotherapy. vol 43. issue 12. 2000-01-21. PMID:10582870. |
mean (sd) measured creatinine clearance (cl(cr)), total clearance (cl(t)), renal clearance (cl(r)), alpha phase half-life, beta phase half-life, and volume of distribution at steady state (v(ss)) were 135 (31) ml/min, 8.8 (2.4) liters/h, 8.1 (2.0) liters/h, 0.33 (0.14) h, 2.8 (0.6) h, and 0.43 (0.10) liters/kg abw, respectively. |
2000-01-21 |
2023-08-12 |
human |
| D J Bernard, I Y Merzlyak, T H Horton, F W Ture. Differential regulation of pituitary gonadotropin subunit messenger ribonucleic acid levels in photostimulated Siberian hamsters. Biology of reproduction. vol 62. issue 1. 2000-01-19. PMID:10611080. |
alpha subunit mrna levels also increased significantly relative to sd control values (maximum 2-fold increase after seven long days; p < 0.03), although to a lesser extent than fshbeta. |
2000-01-19 |
2023-08-12 |
rat |
| T Takatsuji, I Yoshikawa, M S Sasak. Generalized concept of the LET-RBE relationship of radiation-induced chromosome aberration and cell death. Journal of radiation research. vol 40. issue 1. 1999-08-12. PMID:10408178. |
from these assumptions, the frequency of chromosome aberration in surviving cells can be described by y = alpha sd + beta s2d2 with the empirical relation y = alpha d + beta d2 in the low let region, where s = e-cl, alpha is a value proportional to let, beta is a constant, and d is the absorbed dose. |
1999-08-12 |
2023-08-12 |
Not clear |
| W Du, Y Zhang, W Zha. [A study on type I, III and IV collagen production in CCl4 induced rat liver fibrosis]. Zhonghua bing li xue za zhi = Chinese journal of pathology. vol 26. issue 2. 1999-04-16. PMID:10072874. |
to study the dynamic changes of alpha 1 (i), alpha 1 (iii) and alpha i (iv) procollagen mrna and collagen-producing cells during ccl4 induced sd rat liver fibrogenesis (20 weeks). |
1999-04-16 |
2023-08-12 |
rat |
| T H Mäkikallio, J Koistinen, L Jordaens, M P Tulppo, N Wood, B Golosarsky, C K Peng, A L Goldberger, H V Huikur. Heart rate dynamics before spontaneous onset of ventricular fibrillation in patients with healed myocardial infarcts. The American journal of cardiology. vol 83. issue 6. 1999-04-15. PMID:10190403. |
the short-term correlation exponent alpha of rr intervals (0.64 +/- 0.19 vs 1.05 +/- 0.12; p <0.001) and the power-law slope beta (-1.63 +/- 0.28 vs -1.31 +/- 0.20, p <0.001) were lower in the patients before the onset of vf than in the control patients, but the sd and the low-frequency spectral components of rr intervals did not differ between the groups. |
1999-04-15 |
2023-08-12 |
Not clear |
| M H Abraham, R Kumarsingh, J E Cometto-Muñiz, W S Cai. Draize eye scores and eye irritation thresholds in man can be combined into one QSAR. Annals of the New York Academy of Sciences. vol 855. 1999-02-24. PMID:9929667. |
the 37 log(des/p0) values can be combined with log(1/eit) values for 17 vapors into one quantitative structure-activity relationship (qsar) for sensory potency (sp) using our general solvation equation, [formula: see text] where r2 is an excess molar refraction, pi 2h is the compound polarizability/dipolarity, sigma alpha 2h and sigma beta 2h are the compound hydrogen-bond acidity and basicity, and l16 is the gas-hexadecane partition coefficient at 298 k. n is the number of data points, r the correlation coefficient, sd the standard deviation, and f the f-statistic. |
1999-02-24 |
2023-08-12 |
human |
| B Zinman, A J Hanley, S B Harris, J Kwan, I G Fantu. Circulating tumor necrosis factor-alpha concentrations in a native Canadian population with high rates of type 2 diabetes mellitus. The Journal of clinical endocrinology and metabolism. vol 84. issue 1. 1999-02-03. PMID:9920095. |
the mean tnf alpha concentration was 5.6 pg/ml (sd = 2.18) and ranged from 2.0-12.9 pg/ml, with no difference between men and women (p = 0.67). |
1999-02-03 |
2023-08-12 |
human |
| T Koed. [Higher cortical dysfunctions in preterm diplegia: how to evaluate and treat for their pedagogical difficulties]. No to hattatsu = Brain and development. vol 30. issue 3. 1998-07-24. PMID:9613153. |
eeg coherence analysis in sd patients disclosed lower interhemispheric coherence at alpha band frequency in occipital derivations. |
1998-07-24 |
2023-08-12 |
Not clear |
| M Meyer, A Rahmel, C Marconi, B Grassi, J E Skinner, P Cerretell. Is the heart preadapted to hypoxia? Evidence from fractal dynamics of heartbeat interval fluctuations at high altitude (5,050 m). Integrative physiological and behavioral science : the official journal of the Pavlovian Society. vol 33. issue 1. 1998-07-14. PMID:9594353. |
the group averaged alpha exponent (+/- sd) was 0.99 +/- 0.04 (range 0.93-1.04). |
1998-07-14 |
2023-08-12 |
human |
| M H Abraham, R Kumarsingh, J E Cometto-Muniz, W S Cai. An algorithm for nasal pungency thresholds in man. Archives of toxicology. vol 72. issue 4. 1998-07-08. PMID:9587018. |
n = 43, r2 = 0.955, sd = 0.27, f = 201 (i) where the independent variables are solute descriptors: pi(2)h is the dipolarity/polarizability, sigma alpha(2)h and sigma beta(2)h are the overall or effective hydrogen-bond acidity and basicity, and l16 is the solute ostwald solubility coefficient on hexadecane at 25 degrees c. surprisingly, the aliphatic aldehydes and carboxylic acids fit the correlation and with respect to nasal pungency thresholds in man for brief (1-3 s) presentations must be regarded as 'nonreactive' compounds. |
1998-07-08 |
2023-08-12 |
Not clear |
| H Heller, M Könen-Bergmann, A Overlack, K D Schuste. Decreasing diffusion limitation on exercise in lower-graded interstitial lung disease. Pflugers Archiv : European journal of physiology. vol 435. issue 6. 1998-06-08. PMID:9518503. |
in the patients, alpha o was significantly reduced from 1.0066 +/- 0.0004 (mean +/- sd) at rest to 1.0035 +/- 0.0004 during exercise and in the healthy subjects from 1.0072 +/- 0.0008 to 1.0044 +/- 0.0004. |
1998-06-08 |
2023-08-12 |
human |
| C Pihoker, G L Kearns, D French, C Y Bower. Pharmacokinetics and pharmacodynamics of growth hormone-releasing peptide-2: a phase I study in children. The Journal of clinical endocrinology and metabolism. vol 83. issue 4. 1998-04-21. PMID:9543135. |
ghrp-2 pk parameters (mean +/- sd) were: alpha = 13.4 +/- 9.7 h(-1), beta = 1.3 +/- 0.3 h(-1), t(1/2beta) = 0.55 +/- 0.14 h, auc(0-infinity) = 2.02 +/- 1.37 ng/ml x h, cmax = 7.4 +/- 3.8 ng/ml, plasma clearance = 0.66 +/- 0.32 l/h x kg, and apparent volume of distribution = 0.32 +/- 0.14 l/kg. |
1998-04-21 |
2023-08-12 |
Not clear |
| T Koeda, K Takeshit. Electroencephalographic coherence abnormalities in preterm diplegia. Pediatric neurology. vol 18. issue 1. 1998-04-15. PMID:9492092. |
the sd group revealed lower icoh at the occipital pair for the alpha band (p = .0034) and a higher value at the frontal pair for the theta band (p = .0047). |
1998-04-15 |
2023-08-12 |
Not clear |