| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyun Joo Ch. Is essential tremor a degenerative or an electrical disorder? Electrical disorder. International review of neurobiology. vol 163. 2022-06-24. PMID:35750360. |
the tremor network comprises of multiple brain regions including the inferior olive, cerebellum, thalamus, and motor cortex, and there is evidence that a dynamic oscillatory disturbance within this network leads to tremor. |
2022-06-24 |
2023-08-14 |
human |
| Eric J Lang, Adrian Handfort. Is the inferior olive central to essential tremor? Yes. International review of neurobiology. vol 163. 2022-06-24. PMID:35750361. |
much evidence shows that the olivocerebellar system is the main system capable of generating the widespread synchronous oscillatory purkinje cell (pc) complex spike (cs) activity across the cerebellar cortex that would be capable of generating the type of bursting cerebellar output from the deep cerebellar nuclei (dcn) that could underlie tremor. |
2022-06-24 |
2023-08-14 |
mouse |
| Steven Bellows, Joohi Jimenez-Shahe. Is essential tremor a disorder of GABA dysfunction? No. International review of neurobiology. vol 163. 2022-06-24. PMID:35750366. |
the gaba hypothesis states that disinhibition of deep cerebellar neurons due to reduced gabaergic input from purkinje cells results in increased pacemaker activity, leading to rhythmic output to the thalamo-cortical circuit and resulting in tremor. |
2022-06-24 |
2023-08-14 |
mouse |
| Steven Bellows, Joohi Jimenez-Shahe. Is essential tremor a disorder of GABA dysfunction? No. International review of neurobiology. vol 163. 2022-06-24. PMID:35750366. |
although older animal tremor models, such as harmaline tremor, have explored contributions from the inferior olivary body, increasing evidence has pointed to the role of aberrant climbing fiber synaptic organization in oscillatory cerebellar activity and tremor generation. |
2022-06-24 |
2023-08-14 |
mouse |
| Yuke Zhong, Hang Liu, Guohui Liu, Lili Zhao, Chengcheng Dai, Yi Liang, Juncong Du, Xuan Zhou, Lijuan Mo, Changhong Tan, Xinjie Tan, Fen Deng, Xi Liu, Lifen Che. A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease. NPJ Parkinson's disease. vol 8. issue 1. 2022-06-24. PMID:35750692. |
a review on pathology, mechanism, and therapy for cerebellum and tremor in parkinson's disease. |
2022-06-24 |
2023-08-14 |
Not clear |
| Yuke Zhong, Hang Liu, Guohui Liu, Lili Zhao, Chengcheng Dai, Yi Liang, Juncong Du, Xuan Zhou, Lijuan Mo, Changhong Tan, Xinjie Tan, Fen Deng, Xi Liu, Lifen Che. A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease. NPJ Parkinson's disease. vol 8. issue 1. 2022-06-24. PMID:35750692. |
the cerebellum is a growing focus in pd-related researches and is reported to play an important role in tremor in pd. |
2022-06-24 |
2023-08-14 |
Not clear |
| Yuke Zhong, Hang Liu, Guohui Liu, Lili Zhao, Chengcheng Dai, Yi Liang, Juncong Du, Xuan Zhou, Lijuan Mo, Changhong Tan, Xinjie Tan, Fen Deng, Xi Liu, Lifen Che. A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease. NPJ Parkinson's disease. vol 8. issue 1. 2022-06-24. PMID:35750692. |
the cerebellum may participate in the modulation of tremor amplitude via cerebello-thalamo-cortical circuits. |
2022-06-24 |
2023-08-14 |
Not clear |
| Yuke Zhong, Hang Liu, Guohui Liu, Lili Zhao, Chengcheng Dai, Yi Liang, Juncong Du, Xuan Zhou, Lijuan Mo, Changhong Tan, Xinjie Tan, Fen Deng, Xi Liu, Lifen Che. A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease. NPJ Parkinson's disease. vol 8. issue 1. 2022-06-24. PMID:35750692. |
the cerebellar excitatory projections to the ventral intermediate nucleus of the thalamus may be enhanced due to pd-related changes, including dopaminergic/non-dopaminergic system abnormality, white matter damage, and deep nuclei impairment, which may contribute to dysregulation and resistance to levodopa of tremor. |
2022-06-24 |
2023-08-14 |
Not clear |
| Yuke Zhong, Hang Liu, Guohui Liu, Lili Zhao, Chengcheng Dai, Yi Liang, Juncong Du, Xuan Zhou, Lijuan Mo, Changhong Tan, Xinjie Tan, Fen Deng, Xi Liu, Lifen Che. A review on pathology, mechanism, and therapy for cerebellum and tremor in Parkinson's disease. NPJ Parkinson's disease. vol 8. issue 1. 2022-06-24. PMID:35750692. |
this review summarized the pathological, structural, and functional changes of the cerebellum in pd and discussed the role of the cerebellum in pd-related tremor, aiming to provide an overview of the cerebellum-related mechanism of tremor in pd. |
2022-06-24 |
2023-08-14 |
Not clear |
| Cerebellar syndrome as a complication of COVID-19 disease. Neuro endocrinology letters. vol 42. issue 8. 2022-05-01. PMID:35490417. |
this paper presents a case report of a 62-year-old man with cerebellar syndrome, ataxia, intentional tremor and hypermetria when dealing with covid-19 disease. |
2022-05-01 |
2023-08-13 |
Not clear |
| Freek Nieuwhof, Ivan Toni, Arthur W G Buijink, Anne-Fleur van Rootselaar, Bart P C van de Warrenburg, Rick C Helmic. Phase-locked transcranial electrical brain stimulation for tremor suppression in dystonic tremor syndromes. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2022-04-26. PMID:35469732. |
to establish the causal role of the cerebellum and motor cortex in dystonic tremor syndromes, and explore the therapeutic efficacy of phase-locked transcranial alternating current stimulation (tacs). |
2022-04-26 |
2023-08-13 |
Not clear |
| Ming-Kai Pan, Sheng-Han Ku. Essential tremor: Clinical perspectives and pathophysiology. Journal of the neurological sciences. vol 435. 2022-03-17. PMID:35299120. |
the cerebellum has been found to be the key brain region for tremor generation, and structural alterations of the cerebellum have been extensively studied in et. |
2022-03-17 |
2023-08-13 |
Not clear |
| Karen Frei, Daniel D Truon. Medications used to treat tremors. Journal of the neurological sciences. vol 435. 2022-03-13. PMID:35279634. |
medications useful for treating tremor are discussed in this review, including those for action tremor as seen in essential tremor, the resting tremor of parkinson's disease, orthostatic tremor, cerebellar tremor, holmes tremor, dystonic tremor, and drug-induced tremors. |
2022-03-13 |
2023-08-13 |
Not clear |
| Bo Wang, Haotian Wang, Zhidong Cen, Jiachen Yuan, Dehao Yang, Xinhui Chen, Fei Xie, Lebo Wang, Sheng Wu, Zhiyuan Ouyang, Yu-Feng Zang, Wei Lu. White matter alterations in familial cortical myoclonic tremor with epilepsy type 1. Epilepsia. 2022-03-05. PMID:35247271. |
although previous imaging studies have reported cerebellar gray matter loss in patients with familial cortical myoclonic tremor with epilepsy (fcmte), the corresponding white matter alterations remain unknown. |
2022-03-05 |
2023-08-13 |
Not clear |
| Xiaodi Li, Xiao Lv, Churong Liu, Jinlong Ye, Yan Xu, Gengmao Ma, Zhong Li, Yuzhou Wan. Correction to: 3-Hz Postural Tremor in MSA-C and SCA: Revisiting an Old but Underestimated Cerebellar Sign by Posturography. Cerebellum (London, England). 2022-03-03. PMID:35239147. |
correction to: 3-hz postural tremor in msa-c and sca: revisiting an old but underestimated cerebellar sign by posturography. |
2022-03-03 |
2023-08-13 |
Not clear |
| Tao Xie, Mahesh Padmanaban, Adil Javed, David Satzer, Theresa E Towle, Peter Warnke, Vernon L Towl. Effect of Deep Brain Stimulation on Cerebellar Tremor Compared to Non-Cerebellar Tremor Using a Wearable Device in a Patient With Multiple Sclerosis: Case Report. Frontiers in human neuroscience. vol 15. 2022-01-31. PMID:35095448. |
effect of deep brain stimulation on cerebellar tremor compared to non-cerebellar tremor using a wearable device in a patient with multiple sclerosis: case report. |
2022-01-31 |
2023-08-13 |
Not clear |
| Tao Xie, Mahesh Padmanaban, Adil Javed, David Satzer, Theresa E Towle, Peter Warnke, Vernon L Towl. Effect of Deep Brain Stimulation on Cerebellar Tremor Compared to Non-Cerebellar Tremor Using a Wearable Device in a Patient With Multiple Sclerosis: Case Report. Frontiers in human neuroscience. vol 15. 2022-01-31. PMID:35095448. |
the ms tremor is complex because it contains an ataxic intentional tremor component due to the involvement of the cerebellum and cerebellar outflow pathways by ms plaques, which makes the ms tremor, in general, less responsive to medications or deep brain stimulation (dbs) than those associated with essential tremor or parkinson's disease. |
2022-01-31 |
2023-08-13 |
Not clear |
| Tao Xie, Mahesh Padmanaban, Adil Javed, David Satzer, Theresa E Towle, Peter Warnke, Vernon L Towl. Effect of Deep Brain Stimulation on Cerebellar Tremor Compared to Non-Cerebellar Tremor Using a Wearable Device in a Patient With Multiple Sclerosis: Case Report. Frontiers in human neuroscience. vol 15. 2022-01-31. PMID:35095448. |
the cerebellar component has been thought to be the main reason for making dbs less effective, although it is not clear whether it is due to the lack of suppression of the ataxic tremor by dbs or else. |
2022-01-31 |
2023-08-13 |
Not clear |
| Tao Xie, Mahesh Padmanaban, Adil Javed, David Satzer, Theresa E Towle, Peter Warnke, Vernon L Towl. Effect of Deep Brain Stimulation on Cerebellar Tremor Compared to Non-Cerebellar Tremor Using a Wearable Device in a Patient With Multiple Sclerosis: Case Report. Frontiers in human neuroscience. vol 15. 2022-01-31. PMID:35095448. |
the goal of this study was to clarify the effect of dbs on cerebellar tremor compared to non-cerebellar tremor in a patient with ms. by wearing an accelerometer on the index finger of each hand, we were able to quantitatively characterize kinetic tremor by frequency and amplitude, with cerebellar ataxia component on one hand and that without cerebellar component on the other hand, at the beginning and end of the hand movement approaching a target at dbs off and on status. |
2022-01-31 |
2023-08-13 |
Not clear |
| Tao Xie, Mahesh Padmanaban, Adil Javed, David Satzer, Theresa E Towle, Peter Warnke, Vernon L Towl. Effect of Deep Brain Stimulation on Cerebellar Tremor Compared to Non-Cerebellar Tremor Using a Wearable Device in a Patient With Multiple Sclerosis: Case Report. Frontiers in human neuroscience. vol 15. 2022-01-31. PMID:35095448. |
we found that cerebellar tremor surprisingly had as good a response to dbs as the tremor without a cerebellar component, but the function control on cerebellar tremor was not as good due to its distal oscillation, which made the amplitude of tremor increasingly greater as it approached the target. |
2022-01-31 |
2023-08-13 |
Not clear |