| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonio Daniele, Francesco Panza, Antonio Greco, Giancarlo Logroscino, Davide Serip. Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson's Disease? The Potential Role of Zolpidem in the Treatment of Parkinson's Disease. Parkinson's disease. vol 2016. 2016-06-13. PMID:27293955. |
since a high density of zolpidem binding sites is in the two main output structures of the basal ganglia which are abnormally overactive in pd (internal globus pallidus, gpi, and substantia nigra pars reticulata, snr), it was hypothesized that in pd patients zolpidem may induce through gabaa receptors an inhibition of gpi and snr (and, possibly, of the subthalamic nucleus also), resulting in an increased activity of motor cortical areas (such as supplementary motor area), which may give rise to improvement of motor symptoms of pd. |
2016-06-13 |
2023-08-13 |
Not clear |
| D Luke Fischer, Timothy J Collier, Allyson Cole-Strauss, Susan L Wohlgenant, Jack W Lipton, Kathy Steece-Collier, Fredric P Manfredsson, Christopher J Kemp, Caryl E Sortwel. High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine. PloS one. vol 10. issue 7. 2016-05-10. PMID:26222442. |
whereas the globus pallidus interna (gpi) has been less commonly targeted than the subthalamic nucleus (stn), a recent clinical trial suggests that gpi dbs may provide better outcomes for patients with psychiatric comorbidities. |
2016-05-10 |
2023-08-13 |
rat |
| Michelle S Troche, Alexandra E Brandimore, Kelly D Foote, Takashi Morishita, Dennis Chen, Karen W Hegland, Michael S Oku. Swallowing outcomes following unilateral STN vs. GPi surgery: a retrospective analysis. Dysphagia. vol 29. issue 4. 2016-02-08. PMID:24652582. |
there are no studies that compare swallowing outcomes associated with subthalamic nucleus (stn) versus globus pallidus interna (gpi) dbs surgery; therefore, we completed a retrospective study comparing swallowing outcomes in a cohort of patients with pd who underwent unilateral dbs surgery in either the stn or gpi. |
2016-02-08 |
2023-08-12 |
human |
| Omar Mamad, Claire Delaville, Wail Benjelloun, Abdelhamid Benazzou. Dopaminergic control of the globus pallidus through activation of D2 receptors and its impact on the electrical activity of subthalamic nucleus and substantia nigra reticulata neurons. PloS one. vol 10. issue 3. 2016-01-28. PMID:25742005. |
dopaminergic control of the globus pallidus through activation of d2 receptors and its impact on the electrical activity of subthalamic nucleus and substantia nigra reticulata neurons. |
2016-01-28 |
2023-08-13 |
rat |
| Chrystalina A Antoniades, Pedro Rebelo, Christopher Kennard, Tipu Z Aziz, Alexander L Green, James J FitzGeral. Pallidal Deep Brain Stimulation Improves Higher Control of the Oculomotor System in Parkinson's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 38. 2015-12-29. PMID:26400935. |
deep brain stimulation (dbs) of the subthalamic nucleus (stn) has no effect on the aer, but a previous case suggested that dbs of the globus pallidus interna (gpi) might. |
2015-12-29 |
2023-08-13 |
human |
| Henning Schroll, Christian Beste, Fred H Hamke. Combined lesions of direct and indirect basal ganglia pathways but not changes in dopamine levels explain learning deficits in patients with Huntington's disease. The European journal of neuroscience. vol 41. issue 9. 2015-10-12. PMID:25778633. |
in the human basal ganglia, these dysfunctions are accompanied by a loss of striatal medium spiny neurons, dysfunctions of the subthalamic nucleus and globus pallidus, and changes in dopamine receptor binding. |
2015-10-12 |
2023-08-13 |
human |
| Robert J Buchanan, Klevest Gjini, David Darrow, Georgeta Varga, Jennifer L Robinson, Zoltan Nadasd. Glutamate and GABA concentration changes in the globus pallidus internus of Parkinson's patients during performance of implicit and declarative memory tasks: a report of two subjects. Neuroscience letters. vol 589. 2015-08-27. PMID:25596441. |
these results are in line with hypothesized changes in these neurotransmitter levels: an increase of excitatory (glu) input from subthalamic nucleus (stn) to gpi during implicit memory task performance and a decrease of inhibitory inputs (gaba) from globus pallidus externus (gpe) and striatum to gpi during declarative memory performance. |
2015-08-27 |
2023-08-13 |
human |
| Jessica L Wisnowski, Ashok Panigrahy, Michael J Painter, Jon F Watchk. Magnetic resonance imaging of bilirubin encephalopathy: current limitations and future promise. Seminars in perinatology. vol 38. issue 7. 2015-07-20. PMID:25267277. |
infants with chronic bilirubin encephalopathy often demonstrate abnormal bilateral, symmetric, high-signal intensity on t2-weighted magnetic resonance imaging of the globus pallidus and subthalamic nucleus, consistent with the neuropathology of kernicterus. |
2015-07-20 |
2023-08-13 |
Not clear |
| Vincent J J Odekerken, Judith A Boel, Gert J Geurtsen, Ben A Schmand, I P Dekker, Rob J de Haan, P Richard Schuurman, Rob M A de Bi. Neuropsychological outcome after deep brain stimulation for Parkinson disease. Neurology. vol 84. issue 13. 2015-06-18. PMID:25724233. |
to assess the neuropsychological outcome 12 months after bilateral deep brain stimulation (dbs) of the globus pallidus pars interna (gpi) or subthalamic nucleus (stn) for advanced parkinson disease. |
2015-06-18 |
2023-08-13 |
Not clear |
| Takamitsu Watanabe, Ritsuko Hanajima, Yuichiro Shirota, Ryosuke Tsutsumi, Takahiro Shimizu, Toshihiro Hayashi, Yasuo Terao, Yoshikazu Ugawa, Masaki Katsura, Akira Kunimatsu, Kuni Ohtomo, Satoshi Hirose, Yasushi Miyashita, Seiki Konish. Effects of rTMS of pre-supplementary motor area on fronto basal ganglia network activity during stop-signal task. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 12. 2015-06-15. PMID:25810512. |
stop-signal task (sst) has been a key paradigm for probing human brain mechanisms underlying response inhibition, and the inhibition observed in sst is now considered to largely depend on a fronto basal ganglia network consisting mainly of right inferior frontal cortex, pre-supplementary motor area (pre-sma), and basal ganglia, including subthalamic nucleus, striatum (str), and globus pallidus pars interna (gpi). |
2015-06-15 |
2023-08-13 |
human |
| Yoko Mochizuki, Akihiro Kawata, Hirofumi Maruyama, Taku Homma, Kazuhiko Watabe, Hideshi Kawakami, Takashi Komori, Toshio Mizutani, Shiro Matsubar. A Japanese patient with familial ALS and a p.K510M mutation in the gene for FUS (FUS) resulting in the totally locked-in state. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 34. issue 5. 2015-06-10. PMID:24841222. |
the involvement of the globus pallidus, subthalamic nucleus, substantia nigra, cerebellar efferent system, and both upper and lower motor neurons in the present patient was comparable to that described for als patients with different mutations in fus, all of whom progressed to the totally locked-in state. |
2015-06-10 |
2023-08-13 |
Not clear |
| Bettina C Schwab, Tjitske Heida, Yan Zhao, Stephan A van Gils, Richard J A van Weze. Pallidal gap junctions-triggers of synchrony in Parkinson's disease? Movement disorders : official journal of the Movement Disorder Society. vol 29. issue 12. 2015-06-03. PMID:25124148. |
in this study, confocal imaging was used to detect connexin-36, the major neural gap junction protein, in postmortem tissues of pd patients and control subjects in the putamen, subthalamic nucleus (stn), and external and internal globus pallidus (gpe and gpi, respectively). |
2015-06-03 |
2023-08-13 |
human |
| Paul S Larso. Deep brain stimulation for movement disorders. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 11. issue 3. 2015-04-02. PMID:24833244. |
brain targets implanted include the thalamus (most commonly for essential tremor), subthalamic nucleus (most commonly for parkinson's disease), and globus pallidus (parkinson's disease and dystonia), although new targets are currently being explored. |
2015-04-02 |
2023-08-13 |
Not clear |
| Adrian L Oblak, Matthew C Hagen, Kathleen J Sweadner, Ihtsham Haq, Christopher T Whitlow, Joseph A Maldjian, Francine Epperson, Jared F Cook, Mark Stacy, Jill R Murrell, Laurie J Ozelius, Allison Brashear, Bernardino Ghett. Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Acta neuropathologica. vol 128. issue 1. 2015-01-28. PMID:24803225. |
anatomical areas identified as potential targets of i758s mutation were globus pallidus, subthalamic nucleus, red nucleus, inferior olivary nucleus, cerebellar purkinje and granule cell layers, and dentate nucleus. |
2015-01-28 |
2023-08-13 |
human |
| Jordan L Manes, Amy L Parkinson, Charles R Larson, Jeremy D Greenlee, Simon B Eickhoff, Daniel M Corcos, Donald A Robi. Connectivity of the subthalamic nucleus and globus pallidus pars interna to regions within the speech network: a meta-analytic connectivity study. Human brain mapping. vol 35. issue 7. 2015-01-22. PMID:25050431. |
the first aim of this study was to characterize and compare the connectivity of the subthalamic nucleus (stn) and globus pallidus pars interna (gpi) using meta-analytic connectivity modeling. |
2015-01-22 |
2023-08-13 |
Not clear |
| Hsin-Yi Lai, John R Younce, Daniel L Albaugh, Yu-Chieh Jill Kao, Yen-Yu Ian Shi. Functional MRI reveals frequency-dependent responses during deep brain stimulation at the subthalamic nucleus or internal globus pallidus. NeuroImage. vol 84. 2014-12-18. PMID:23988274. |
high frequency stimulation at both the subthalamic nucleus (stn) and internal globus pallidus (gpi) has been used with great success for the symptomatic treatment of pd, although the therapeutic mechanisms of action remain elusive. |
2014-12-18 |
2023-08-12 |
rat |
| Birgit R Plantinga, Yasin Temel, Alard Roebroeck, Kâmil Uludağ, Dimo Ivanov, Mark L Kuijf, Bart M Ter Haar Romeni. Ultra-high field magnetic resonance imaging of the basal ganglia and related structures. Frontiers in human neuroscience. vol 8. 2014-11-21. PMID:25414656. |
sequences sensitive to magnetic susceptibility such as t2(*) and susceptibility weighted imaging and their maps in general showed the best visualization of target structures, including a separation between the subthalamic nucleus and the substantia nigra, the lamina pallidi medialis and lamina pallidi incompleta within the globus pallidus and substructures of the thalamus, including the ventral intermediate nucleus (vim). |
2014-11-21 |
2023-08-13 |
Not clear |
| Yi Liu, Weina Li, Changhong Tan, Xi Liu, Xin Wang, Yuejiang Gui, Lu Qin, Fen Deng, Changlin Hu, Lifen Che. Meta-analysis comparing deep brain stimulation of the globus pallidus and subthalamic nucleus to treat advanced Parkinson disease. Journal of neurosurgery. vol 121. issue 3. 2014-11-18. PMID:24905564. |
meta-analysis comparing deep brain stimulation of the globus pallidus and subthalamic nucleus to treat advanced parkinson disease. |
2014-11-18 |
2023-08-13 |
Not clear |
| Timothy Ross Lukins, Stephen Tisch, Benjamin Jonke. The latest evidence on target selection in deep brain stimulation for Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 21. issue 1. 2014-08-21. PMID:24210797. |
this paper aims to review the latest and most relevant studies evaluating subthalamic nucleus (stn) and globus pallidus interna (gpi) stimulation. |
2014-08-21 |
2023-08-12 |
Not clear |
| Anna Castrioto, Elena Mor. New targets for deep brain stimulation treatment of Parkinson's disease. Expert review of neurotherapeutics. vol 13. issue 12. 2014-08-06. PMID:24215284. |
deep brain stimulation (dbs) of the subthalamic nucleus (stn) and the globus pallidus pars interna (gpi) has been shown to be an effective treatment for patients with parkinson's disease. |
2014-08-06 |
2023-08-12 |
Not clear |