| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Young Hee Jung, Hyemin Jang, Sungbeen Park, Hee Jin Kim, Sang Won Seo, Guk Bae Kim, Young-Min Shon, Sungshin Kim, Duk L N. Effectiveness of Personalized Hippocampal Network-Targeted Stimulation in Alzheimer Disease: A Randomized Clinical Trial. JAMA network open. vol 7. issue 5. 2024-05-06. PMID:38709534. |
effectiveness of personalized hippocampal network-targeted stimulation in alzheimer disease: a randomized clinical trial. |
2024-05-06 |
2024-05-08 |
Not clear |
| Anna Onisiforou, Christiana C Christodoulou, Eleni Zamba-Papanicolaou, Panos Zanos, Polymnia Georgio. Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer's disease. Frontiers in endocrinology. vol 15. 2024-05-01. PMID:38689734. |
transcriptomic analysis reveals sex-specific patterns in the hippocampus in alzheimer's disease. |
2024-05-01 |
2024-05-03 |
Not clear |
| Anna Onisiforou, Christiana C Christodoulou, Eleni Zamba-Papanicolaou, Panos Zanos, Polymnia Georgio. Transcriptomic analysis reveals sex-specific patterns in the hippocampus in Alzheimer's disease. Frontiers in endocrinology. vol 15. 2024-05-01. PMID:38689734. |
the hippocampus, vital for memory and learning, is among the first brain regions affected in alzheimer's disease (ad) and exhibits adult neurogenesis. |
2024-05-01 |
2024-05-03 |
Not clear |
| Jens Stepan, Daniel E Heinz, Frederik Dethloff, Svenja Wiechmann, Silvia Martinelli, Kathrin Hafner, Tim Ebert, Ellen Junglas, Alexander S Häusl, Max L Pöhlmann, Mira Jakovcevski, Julius C Pape, Anthony S Zannas, Thomas Bajaj, Anke Hermann, Xiao Ma, Hermann Pavenstädt, Mathias V Schmidt, Alexandra Philipsen, Christoph W Turck, Jan M Deussing, Gerhard Rammes, Andrew C Robinson, Antony Payton, Michael C Wehr, Valentin Stein, Christopher Murgatroyd, Joachim Kremerskothen, Bernhard Kuster, Carsten T Wotjak, Nils C Gasse. Inhibiting Hippo pathway kinases releases WWC1 to promote AMPAR-dependent synaptic plasticity and long-term memory in mice. Science signaling. vol 17. issue 834. 2024-04-30. PMID:38687825. |
mst1/2 inhibition enhanced synaptic transmission in mouse hippocampal brain slices and improved cognition in healthy male mice and in male mouse models of alzheimer's disease and aging. |
2024-04-30 |
2024-05-03 |
mouse |
| Anastasiia Nefodova, Mariia Rudyk, Roman Dovhyi, Taisa Dovbynchuk, Nataliia Dzubenko, Ganna Tolstanova, Larysa Skivk. Systemic inflammation in Aβ Brain research. 2024-04-28. PMID:38679313. |
systemic inflammation in aβ alzheimer disease (ad) is the most frequent cause of dementia, and the most common neurodegenerative disease, which is characterized by memory impairment, neuronal death, and synaptic loss in the hippocampus. |
2024-04-28 |
2024-05-01 |
rat |
| Dongfang Jiang, Hongmei Liu, Tingting Li, Song Zhao, Keyan Yang, Fuwen Yao, Bo Zhou, Haiping Feng, Sijia Wang, Jiaqi Shen, Jinglan Tang, Yu-Xin Zhang, Yun Wang, Caixia Guo, Tie-Shan Tan. Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease. Translational neurodegeneration. vol 13. issue 1. 2024-04-27. PMID:38671492. |
agomirs upregulating carboxypeptidase e expression rescue hippocampal neurogenesis and memory deficits in alzheimer's disease. |
2024-04-27 |
2024-04-29 |
Not clear |
| Dongfang Jiang, Hongmei Liu, Tingting Li, Song Zhao, Keyan Yang, Fuwen Yao, Bo Zhou, Haiping Feng, Sijia Wang, Jiaqi Shen, Jinglan Tang, Yu-Xin Zhang, Yun Wang, Caixia Guo, Tie-Shan Tan. Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease. Translational neurodegeneration. vol 13. issue 1. 2024-04-27. PMID:38671492. |
however, it remains unknown whether these events occur in the hippocampus, and what the role of cpe is in the adult hippocampal neurogenesis in the context of alzheimer's disease (ad). |
2024-04-27 |
2024-04-29 |
Not clear |
| Sara Seoane, Martijn van den Heuvel, Ángel Acebes, Niels Jansse. The subcortical default mode network and Alzheimer's disease: a systematic review and meta-analysis. Brain communications. vol 6. issue 2. 2024-04-26. PMID:38665961. |
in alzheimer's disease, we observed a left-lateralized cluster of decrease in functional connectivity which covered the medial temporal lobe and amygdala and showed overlap with the default mode network in a portion covering parts of the left anterior hippocampus and left amygdala. |
2024-04-26 |
2024-04-28 |
Not clear |
| Carlos Antonio García-Carlos, Gustavo Basurto-Islas, George Perry, Siddhartha Mondragón-Rodrígue. Meta-Analysis in Transgenic Alzheimer's Disease Mouse Models Reveals Opposite Brain Network Effects of Amyloid-β and Phosphorylated Tau Proteins. Journal of Alzheimer's disease : JAD. 2024-04-26. PMID:38669540. |
cognitive deficits observed in alzheimer's disease (ad) patients have been correlated with altered hippocampal activity. |
2024-04-26 |
2024-04-29 |
mouse |
| Erratum to: Loss in PKC Epsilon Causes Downregulation of MnSOD and BDNF Expression in Neurons of Alzheimer's Disease Hippocampus. Journal of Alzheimer's disease : JAD. 2024-04-26. PMID:38669561. |
erratum to: loss in pkc epsilon causes downregulation of mnsod and bdnf expression in neurons of alzheimer's disease hippocampus. |
2024-04-26 |
2024-04-29 |
Not clear |
| Bing-Yi Wang, Si-Yu Liu, Kai-Min Hao, Wen-Xiu Q. [Age-dependent expression of HSP90 in the hippocampus of APP/PS1 mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 76. issue 2. 2024-04-25. PMID:38658375. |
the present study aims to observe the change in expression of heat shock protein 90 (hsp90) along with amyloid-β (aβ) and phosphorylated tau (p-tau) protein levels in the hippocampus tissue of alzheimer's disease (ad) transgenic animal model with age. |
2024-04-25 |
2024-04-28 |
mouse |
| Sarah Nicolas, Sebastian Dohm-Hansen, Aonghus Lavelle, Thomaz F S Bastiaanssen, Jane A English, John F Cryan, Yvonne M Nola. Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats. Translational psychiatry. vol 14. issue 1. 2024-04-24. PMID:38658547. |
lifestyle factors, especially exercise, impact the manifestation and progression of psychiatric and neurodegenerative disorders such as depression and alzheimer's disease, mediated by changes in hippocampal neuroplasticity. |
2024-04-24 |
2024-04-28 |
rat |
| Rafaela Morais-Ribeiro, Francisco C Almeida, Ana Coelho, Tiago Gil Oliveir. Differential atrophy along the longitudinal hippocampal axis in Alzheimer's disease for the Alzheimer's Disease Neuroimaging Initiative. The European journal of neuroscience. 2024-04-24. PMID:38654447. |
differential atrophy along the longitudinal hippocampal axis in alzheimer's disease for the alzheimer's disease neuroimaging initiative. |
2024-04-24 |
2024-04-28 |
human |
| Rafaela Morais-Ribeiro, Francisco C Almeida, Ana Coelho, Tiago Gil Oliveir. Differential atrophy along the longitudinal hippocampal axis in Alzheimer's disease for the Alzheimer's Disease Neuroimaging Initiative. The European journal of neuroscience. 2024-04-24. PMID:38654447. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder that primarily affects the hippocampus. |
2024-04-24 |
2024-04-28 |
human |
| Aya Hassouneh, Bradley Bazuin, Alessander Danna-Dos-Santos, Ilgin Acar, Ikhlas Abdel-Qade. Feature Importance Analysis and Machine Learning for Alzheimer's Disease Early Detection: Feature Fusion of the Hippocampus, Entorhinal Cortex, and Standardized Uptake Value Ratio. Digital biomarkers. vol 8. issue 1. 2024-04-23. PMID:38650695. |
feature importance analysis and machine learning for alzheimer's disease early detection: feature fusion of the hippocampus, entorhinal cortex, and standardized uptake value ratio. |
2024-04-23 |
2024-04-26 |
Not clear |
| Tiantian Huang, Xiao-Kang Gong, Zheng Liang, Rong Yang, Liangwei Wu, Chaoqing Yang, Mengjuan Wu, Xiao-Chuan Wang, Xi-Ji Shu, Jian Ba. Exercised-enriched blood plasma rescues hippocampal impairments and cognitive deficits in an Alzheimer's disease model. Biochimica et biophysica acta. Molecular basis of disease. 2024-04-23. PMID:38653353. |
exercised-enriched blood plasma rescues hippocampal impairments and cognitive deficits in an alzheimer's disease model. |
2024-04-23 |
2024-04-26 |
mouse |
| Shafiq Ul Rehman, Noha Tarek, Caroline Magdy, Mohammed Kamel, Mohammed Abdelhalim, Alaa Melek, Lamees N Mahmoud, Ibrahim Sade. AI-based tool for early detection of Alzheimer's disease. Heliyon. vol 10. issue 8. 2024-04-22. PMID:38644855. |
the hippocampus, a pivotal early affected region linked to memory, plays a central role in classifying patients into three categories: cognitively normal (cn), representing individuals without cognitive impairment; mild cognitive impairment (mci), indicative of a subtle decline in cognitive abilities; and ad, denoting alzheimer's disease. |
2024-04-22 |
2024-04-24 |
Not clear |
| Ketaki A Katdare, Andrew Kjar, Natasha M O'Brown, Emma H Neal, Alexander G Sorets, Alena Shostak, Wilber Romero-Fernandez, Alexander J Kwiatkowski, Kate Mlouk, Hyosung Kim, Rebecca P Cowell, Katrina R Schwensen, Kensley B Horner, John T Wilson, Matthew S Schrag, Sean G Megason, Ethan S Lippman. IQGAP2 regulates blood-brain barrier immune dynamics. bioRxiv : the preprint server for biology. 2024-04-22. PMID:38645082. |
human tissue analyses also reveal that alzheimer's disease is associated with reduced hippocampal iqgap2. |
2024-04-22 |
2024-04-24 |
mouse |
| Gabriel S Stephens, Jin Park, Andrew Eagle, Jason You, Manuel Silva-Pérez, Chia-Hsuan Fu, Sumin Choi, Corey P St Romain, Chiho Sugimoto, Shelly A Buffington, Yi Zheng, Mauro Costa-Mattioli, Yin Liu, A J Robison, Jeannie Chi. Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice. Progress in neurobiology. 2024-04-20. PMID:38642602. |
recurrent seizures lead to accumulation of the activity-dependent transcription factor ∆fosb in hippocampal dentate granule cells in both mouse models of epilepsy and mouse models of alzheimer's disease (ad), which is also associated with increased incidence of seizures. |
2024-04-20 |
2024-04-23 |
mouse |
| Claudia Dorado-Martínez, Enrique Montiel-Flores, Jose Luis Ordoñez-Librado, Ana Luisa Gutierrez-Valdez, Cesar Alfonso Garcia-Caballero, Javier Sanchez-Betancourt, Leonardo Reynoso-Erazo, Rocio Tron-Alvarez, Vianey Rodríguez-Lara, Maria Rosa Avila-Cost. Histological and Memory Alterations in an Innovative Alzheimer's Disease Animal Model by Vanadium Pentoxide Inhalation. Journal of Alzheimer's disease : JAD. 2024-04-19. PMID:38640149. |
previous work from our group has shown that chronic exposure to vanadium pentoxide (v2o5) causes cytoskeletal alterations suggesting that v2o5 can interact with cytoskeletal proteins through polymerization and tyrosine phosphatases inhibition, causing alzheimer's disease (ad)-like hippocampal cell death. |
2024-04-19 |
2024-04-22 |
Not clear |