| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyu-Man Han, Byung-Joo Ham, Yong-Ku Ki. Development of Neuroimaging-Based Biomarkers in Major Depression. Advances in experimental medicine and biology. vol 1305. 2021-04-12. PMID:33834396. |
particularly, structural and functional magnetic resonance imaging (mri) studies have reported that the brain structures deeply involved in emotion regulation or reward processing including the amygdala, prefrontal cortex (pfc), anterior cingulate cortex (acc), ventral striatum, and hippocampus are key regions that provide useful information about diagnosis and treatment outcome prediction in mdd. |
2021-04-12 |
2023-08-13 |
Not clear |
| Kayla J Colvin, Henry S Killen, Maxwell J Kanter, Maximilian C Halperin, Liv Engel, Paul J Curri. Brain Site-Specific Inhibitory Effects of the GLP-1 Analogue Exendin-4 on Alcohol Intake and Operant Responding for Palatable Food. International journal of molecular sciences. vol 21. issue 24. 2021-04-01. PMID:33352692. |
results indicated that glp-1 receptor signaling effectively suppressed voluntary alcohol intake when injected into the ventral tegmental area (vta), the accumbens core (nacc) and shell (nacs), the dorsomedial hippocampus (dmhipp), and the lateral hypothalamus (lh), which are all structures linked to brain reward mechanisms. |
2021-04-01 |
2023-08-13 |
rat |
| Xiaohan Zhang, Lu Liu, Guodong Long, Jing Jiang, Shenquan Li. Episodic memory governs choices: An RNN-based reinforcement learning model for decision-making task. Neural networks : the official journal of the International Neural Network Society. vol 134. 2021-03-23. PMID:33276194. |
the results indicate that salient events stored in the hippocampus could be prioritized to propagate reward information, and thus allow decision-makers to learn a strategy faster. |
2021-03-23 |
2023-08-13 |
monkey |
| Stefan Koelsc. A coordinate-based meta-analysis of music-evoked emotions. NeuroImage. vol 223. 2021-03-08. PMID:32898679. |
the results of an activation likelihood estimation (ale) indicate large clusters in a range of structures, including amygdala, anterior hippocampus, auditory cortex, and numerous structures of the reward network (ventral and dorsal striatum, anterior cingulate cortex, orbitofrontal cortex, secondary somatosensory cortex). |
2021-03-08 |
2023-08-13 |
human |
| Hannah S Wirtshafter, Matthew A Wilso. Differences in reward biased spatial representations in the lateral septum and hippocampus. eLife. vol 9. 2021-02-17. PMID:32452763. |
differences in reward biased spatial representations in the lateral septum and hippocampus. |
2021-02-17 |
2023-08-13 |
rat |
| Hannah S Wirtshafter, Matthew A Wilso. Differences in reward biased spatial representations in the lateral septum and hippocampus. eLife. vol 9. 2021-02-17. PMID:32452763. |
while ls place cells are less numerous than in hippocampus, they are similar to the hippocampus in field size and number of fields per cell, but with field shape and center distributions that are more skewed toward reward. |
2021-02-17 |
2023-08-13 |
rat |
| Liyana T Swirsky, Ryan M Marinacci, Julia Spanio. Reward anticipation selectively boosts encoding of gist for visual objects. Scientific reports. vol 10. issue 1. 2021-01-13. PMID:33214646. |
these findings are consistent with the theory of long-axis specialization along the human hippocampus, which localizes gist-based memory processes to the anterior hippocampus, a region highly interconnected with the dopaminergic reward network. |
2021-01-13 |
2023-08-13 |
human |
| Kelsey Prena, Hu Cheng, Sharlene D Newma. Hippocampal Neurotransmitter Inhibition Suppressed During Gaming Explained by Skill Rather Than Gamer Status. Frontiers in human neuroscience. vol 14. 2020-12-31. PMID:33364929. |
goal-directed spatial decision making video games combine spatial mapping, memory, and reward; all of which can involve hippocampal excitation through suppression of an inhibitory neurotransmitter, γ-aminobutyric acid (gaba). |
2020-12-31 |
2023-08-13 |
human |
| Hasan Alhaddad, Woonyen Wong, Adam T Sari, Laura E Crotty Alexander, Youssef Sar. Effects of 3-Month Exposure to E-Cigarette Aerosols on Glutamatergic Receptors and Transporters in Mesolimbic Brain Regions of Female C57BL/6 Mice. Toxics. vol 8. issue 4. 2020-12-26. PMID:33137879. |
in this study, we evaluated the effect of three months' continuous exposure to e-cig vapor (juul pods), containing a high nicotine concentration, on the expression of glutamate receptors and transporters in drug reward brain regions such as the nucleus accumbens (nac) core (nac-core), nac shell (nac-shell) and hippocampus (hip) in female c57bl/6 mice. |
2020-12-26 |
2023-08-13 |
mouse |
| Corey B Puryear, Julie Brooks, Laura Tan, Karen Smith, Yan Li, Jacobi Cunningham, Mark S Todtenkopf, Reginald L Dean, Connie Sanche. Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? Neuroscience and biobehavioral reviews. vol 108. 2020-12-21. PMID:31821832. |
this article highlights how the opioid system potently modulates mesolimbic circuitry underlying motivation and reward processing, limbic circuitry underlying fear and anxiety responses, cortical and hippocampal circuitry underlying a variety of cognitive functions, as well as broad functional and structural plasticity mechanisms. |
2020-12-21 |
2023-08-13 |
Not clear |
| Jeffrey L Barr, Xiangdang Shi, Michael Zaykaner, Ellen M Unterwal. Glycogen Synthase Kinase 3β in the Ventral Hippocampus is Important for Cocaine Reward and Object Location Memory. Neuroscience. vol 425. 2020-12-15. PMID:31783102. |
glycogen synthase kinase 3β in the ventral hippocampus is important for cocaine reward and object location memory. |
2020-12-15 |
2023-08-13 |
mouse |
| Jeffrey L Barr, Xiangdang Shi, Michael Zaykaner, Ellen M Unterwal. Glycogen Synthase Kinase 3β in the Ventral Hippocampus is Important for Cocaine Reward and Object Location Memory. Neuroscience. vol 425. 2020-12-15. PMID:31783102. |
the ventral hippocampus is a component of the neural circuitry involved with context-associated memory for reward and generation of appropriate behavioral responses to context. |
2020-12-15 |
2023-08-13 |
mouse |
| Jeffrey L Barr, Xiangdang Shi, Michael Zaykaner, Ellen M Unterwal. Glycogen Synthase Kinase 3β in the Ventral Hippocampus is Important for Cocaine Reward and Object Location Memory. Neuroscience. vol 425. 2020-12-15. PMID:31783102. |
these results indicate that gsk3β signaling in the ventral hippocampus is differentially involved in the formation of place-drug reward association dependent upon drug class. |
2020-12-15 |
2023-08-13 |
mouse |
| Elisa Ciaramelli, Hana Burianová, Antonino Vallesi, Roberto Cabeza, Morris Moscovitc. Functional Interplay Between Posterior Parietal Cortex and Hippocampus During Detection of Memory Targets and Non-targets. Frontiers in neuroscience. vol 14. 2020-11-24. PMID:33224020. |
we found that (1) dorsal parietal cortex (dpc) was more engaged during detection of items studied once compared to three times, whereas regions in the ventral parietal cortex (vpc) responded more to items studied multiple times; (2) dpc, within a network of brain regions functionally connected to the anterior hippocampus, responded more to items consistent with retrieval goals (associated with high reward); (3) vpc, within a network of brain regions functionally connected to the posterior hippocampus, responded more to items not aligned with retrieval goals (i.e., unexpected). |
2020-11-24 |
2023-08-13 |
human |
| Alexandre Y Dombrovski, Beatriz Luna, Michael N Hallquis. Differential reinforcement encoding along the hippocampal long axis helps resolve the explore-exploit dilemma. Nature communications. vol 11. issue 1. 2020-11-06. PMID:33106508. |
the hippocampus binds reward information into allocentric cognitive maps to support navigation and foraging in such spaces. |
2020-11-06 |
2023-08-13 |
human |
| Alexandre Y Dombrovski, Beatriz Luna, Michael N Hallquis. Differential reinforcement encoding along the hippocampal long axis helps resolve the explore-exploit dilemma. Nature communications. vol 11. issue 1. 2020-11-06. PMID:33106508. |
here we report that human posterior hippocampus (ph) invigorates exploration while anterior hippocampus (ah) supports the transition to exploitation on a reinforcement learning task with a spatially structured reward function. |
2020-11-06 |
2023-08-13 |
human |
| Guan-Ling Lu, Ming Tatt Lee, Lih-Chu Chio. Orexin-mediated restoration of hippocampal synaptic potentiation in mice with established cocaine-conditioned place preference. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30276922. |
orexins (also called hypocretins) are implicated in reward and addiction, but little is known about their role(s) in the association between hippocampal synaptic plasticity and drug preference. |
2020-10-28 |
2023-08-13 |
mouse |
| Marissa Sobolewski, Garima Singh, Jay S Schneider, Deborah A Cory-Slecht. Different Behavioral Experiences Produce Distinctive Parallel Changes in, and Correlate With, Frontal Cortex and Hippocampal Global Post-translational Histone Levels. Frontiers in integrative neuroscience. vol 12. 2020-10-01. PMID:30072878. |
to begin to address this question, male and female mice were subjected to either a fixed interval (fi) schedule of food reward, or a single episode of forced swim followed by restraint stress, or no explicit behavioral experience after which global expression levels of two activating (h3k9ac and h3k4me3) and two repressive (h3k9me2 and h3k27me3) post-translational histone modifications (pthms), were measured in hippocampus (hipp) and frontal cortex (fc). |
2020-10-01 |
2023-08-13 |
mouse |
| D Y Sakae, S J Marti. Formation of a morphine-conditioned place preference does not change the size of evoked potentials in the ventral hippocampus-nucleus accumbens projection. Scientific reports. vol 9. issue 1. 2020-10-01. PMID:30914714. |
the synapses linking ventral hippocampal outputs to medium spiny neurons of the accumbens may be key sites for the formation and storage of associations between place or context and reward, both drug-related and natural. |
2020-10-01 |
2023-08-13 |
rat |
| S Galoi. NEW BLOOD PRESSURE TARGETS IN NON-DIABETIC PATIENTS AND INSULIN RESISTANCE IN BRAIN. Acta endocrinologica (Bucharest, Romania : 2005). vol 12. issue 1. 2020-10-01. PMID:31258812. |
in limited area of the human brain, insulin acts in modulation of body weight by food intake and modification of metabolism: hypothalamus (the central regulator of whole- body energy homeostasis and of food intake), prefrontal cortex (inhibitory control of eating), hippocampus (memory) and the fusiform gyrus (recognition of food, positive emotions, reward). |
2020-10-01 |
2023-08-13 |
human |