| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Irena Majkutewicz, Ewelina Kurowska-Rucińska, Jan Ruciński, Dorota Myślińska, Beata Grembecka, Jagoda Mantej, Katarzyna P Dzi. Diverse Efficacy of Dimethyl Fumarate in Alleviating the Late Streptozotocin-Induced Cognitive Impairment and Neuropathological Features in Rat. Molecular neurobiology. 2024-03-02. PMID:38430351. |
our previous study showed that dimethyl fumarate (dmf) treatment performed within three weeks after intracerebroventricular (icv) injection of streptozotocin (stz) attenuated spatial memory impairment, hippocampal neurodegeneration, and neuroinflammation in rats. |
2024-03-02 |
2024-03-04 |
human |
| Irena Majkutewicz, Ewelina Kurowska-Rucińska, Jan Ruciński, Dorota Myślińska, Beata Grembecka, Jagoda Mantej, Katarzyna P Dzi. Diverse Efficacy of Dimethyl Fumarate in Alleviating the Late Streptozotocin-Induced Cognitive Impairment and Neuropathological Features in Rat. Molecular neurobiology. 2024-03-02. PMID:38430351. |
spatial memory was assessed with morris water maze (mwm), general brain level of amyloid β (aβ) and p-tau was measured by western blot, immunofluorescent labelling of active microglia (iba1), aβ and p-tau and histological assay of neurodegeneration (fluoro-jade c) were performed in hippocampus and cortex. |
2024-03-02 |
2024-03-04 |
human |
| Gustavo D B Machado, Alexis L Schnitzler, Aaron W Fleischer, Sarah B Beamish, Karyn M Fric. G protein-coupled estrogen receptor (GPER) in the dorsal hippocampus regulates memory consolidation in gonadectomized male mice, likely via different signaling mechanisms than in female mice. Hormones and behavior. vol 161. 2024-03-01. PMID:38428223. |
in ovx mice, bilateral infusion of the gper agonist g-1 into the dorsal hippocampus (dh) enhances object recognition and spatial memory consolidation in a manner dependent on rapid activation of c-jun n-terminal kinase (jnk) signaling, cofilin phosphorylation, and actin polymerization in the dh. |
2024-03-01 |
2024-03-04 |
mouse |
| Jose J Ferrero, Ahnaf R Hassan, Zelin Yu, Zifang Zhao, Liang Ma, Cynthia Wu, Shan Shao, Takeshi Kawano, Judah Engel, Werner Doyle, Orrin Devinsky, Dion Khodagholy, Jennifer N Gelina. Closed-loop electrical stimulation to prevent focal epilepsy progression and long-term memory impairment. bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405990. |
spatiotemporally targeted closed-loop electrical stimulation triggered on hippocampal ied occurrence eliminated the abnormal cortical activity patterns, preventing spread of the epileptic network and ameliorating long-term spatial memory deficits in rodents. |
2024-02-26 |
2024-02-28 |
human |
| Shuai Zhang, Zhongsheng Guo, Yihao Xu, Jinrui Mi, Jun Liu, Zichun Li, Xiaofeng Xie, Guizhi X. Transcranial magneto-acoustic stimulation improves spatial memory and modulates hippocampal neural oscillations in a mouse model of Alzheimer's disease. Frontiers in neuroscience. vol 18. 2024-02-22. PMID:38384480. |
transcranial magneto-acoustic stimulation improves spatial memory and modulates hippocampal neural oscillations in a mouse model of alzheimer's disease. |
2024-02-22 |
2024-02-24 |
mouse |
| Wembley R Vilela, Lisley S Ramalho, Luiz R G Bechara, João V Cabral-Costa, Julian D C Serna, Alicia J Kowaltowski, Gilberto F Xavier, Julio C B Ferreira, Andreza Fabro de Be. Metabolic dysfunction induced by HFD + L-NAME preferentially affects hippocampal mitochondria, impacting spatial memory in rats. Journal of bioenergetics and biomembranes. 2024-02-20. PMID:38374292. |
metabolic dysfunction induced by hfd + l-name preferentially affects hippocampal mitochondria, impacting spatial memory in rats. |
2024-02-20 |
2024-02-22 |
rat |
| Maha Elbeltagy, Ramzi A Al-Horani, Tala S Alsharaeh, Amro H Alkhatib, Ibrahim Alawaisheh, Ahmad A Abuhani, Ahmed Salma. The Counter Effect of Exercise on Cisplatin-Induced Cognitive and Proliferation Impairments. Cureus. vol 16. issue 1. 2024-02-19. PMID:38371164. |
spatial memory was evaluated using the novel object recognition (nor) task, and hippocampal proliferation and oxidative stress were examined using ki-67 and glutathione peroxidase (gpx) immunohistochemistry (ihc) staining, respectively. |
2024-02-19 |
2024-02-21 |
mouse |
| Hideyuki Takahashi, Sanaea Bhagwagar, Sarah H Nies, Hongping Ye, Xianlin Han, Marius T Chiasseu, Guilin Wang, Ian R Mackenzie, Stephen M Strittmatte. Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase. Nature communications. vol 15. issue 1. 2024-02-16. PMID:38365772. |
the increased inclusions paradoxically protect against spatial memory deficit and hippocampal neurodegeneration. |
2024-02-16 |
2024-02-19 |
mouse |
| Charles H Wallace, Giovanni Oliveros, Lei Xie, Peter Serrano, Patricia Rockwell, Maria Figueiredo-Pereir. Potential Alzheimer's early biomarkers in a transgenic rat model and benefits of diazoxide/dibenzoylmethane co-treatment on spatial memory and AD-pathology. Scientific reports. vol 14. issue 1. 2024-02-14. PMID:38355687. |
dz/dib-treatment mitigated spatial memory deficits and buildup of hippocampal aβ plaques and tau phf in 11-month tgf344-ad rats but had no effect on wild-type littermates. |
2024-02-14 |
2024-02-17 |
rat |
| Judit Català-Solsona, Stefano Lutzu, Pablo J Lituma, Cristina Fábregas-Ordoñez, Dolores Siedlecki, Lydia Giménez-Llort, Alfredo J Miñano-Molina, Carlos A Saura, Pablo E Castillo, José Rodriguez-Álvare. Nr4a2 blocks oAβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the APP bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328087. |
nr4a2 blocks oaβ-mediated synaptic plasticity dysfunction and ameliorates spatial memory deficits in the app alzheimer's disease ad is associated with disruptions in neuronal communication, especially in brain regions crucial for learning and memory, such as the hippocampus. |
2024-02-08 |
2024-02-10 |
mouse |
| Jiuyang Ding, Jun Wu, Xiaotao Hou, Li Yang, Yingdong Gao, Juan Zheng, Nannan Jia, Zheng He, Hui Zhang, Chengfei Wang, Xiaolan Qi, Jiang Huang, Xianglin Pei, Jiawen Wan. α-synuclein-lack expression rescues methamphetamine-induced mossy fiber degeneration in dorsal hippocampal CA3. Neurotoxicology. vol 101. 2024-02-07. PMID:38311184. |
methamphetamine (meth) - induced cognitive impairments may be related to synaptic degeneration at mossy fiber terminals, critical for spatial memory formation in hippocampal circuits. |
2024-02-07 |
2024-02-10 |
Not clear |
| Ayse Arzu Yigit, Sevtap Kilinc, Rukiye Olcuoglu, Elif Azra Arnou. The Effects of Orlistat on Oxidative Stress, Recognition Memory, Spatial Memory and Hippocampal Tissue in Experimentally Induced Obesity in Rats. Behavioural brain research. 2024-02-04. PMID:38311071. |
the effects of orlistat on oxidative stress, recognition memory, spatial memory and hippocampal tissue in experimentally induced obesity in rats. |
2024-02-04 |
2024-02-07 |
rat |
| Ayse Arzu Yigit, Sevtap Kilinc, Rukiye Olcuoglu, Elif Azra Arnou. The Effects of Orlistat on Oxidative Stress, Recognition Memory, Spatial Memory and Hippocampal Tissue in Experimentally Induced Obesity in Rats. Behavioural brain research. 2024-02-04. PMID:38311071. |
this study investigates the impact of orlistat on oxidative stress, spatial memory, recognition memory, and hippocampal tissue in obese rats. |
2024-02-04 |
2024-02-07 |
rat |
| Ayse Arzu Yigit, Sevtap Kilinc, Rukiye Olcuoglu, Elif Azra Arnou. The Effects of Orlistat on Oxidative Stress, Recognition Memory, Spatial Memory and Hippocampal Tissue in Experimentally Induced Obesity in Rats. Behavioural brain research. 2024-02-04. PMID:38311071. |
our study demonstrates that orlistat administration exerts beneficial effects on oxidative stress, spatial memory, recognition memory, and hippocampal tissue in obese rats. |
2024-02-04 |
2024-02-07 |
rat |
| Clara Sanchez, Cécilia Colson, Nadine Gautier, Pascal Noser, Juliette Salvi, Maxime Villet, Lucile Fleuriot, Caroline Peltier, Pascal Schlich, Frédéric Brau, Ariane Sharif, Ali Altintas, Ez-Zoubir Amri, Jean-Louis Nahon, Nicolas Blondeau, Alexandre Benani, Romain Barrès, Carole Rovèr. Dietary fatty acid composition drives neuroinflammation and impaired behavior in obesity. Brain, behavior, and immunity. 2024-02-03. PMID:38309640. |
only hfd-hi increased anxiety and impaired spatial memory, together with increased inflammation in the hypothalamus and hippocampus. |
2024-02-03 |
2024-02-06 |
mouse |
| Lucas Gephine, Candice M Roux, Thomas Freret, Michel Boulouard, Marianne Lege. Vulnerability of Spatial Pattern Separation in 5xFAD Alzheimer's Disease Mouse Model. Journal of Alzheimer's disease : JAD. 2024-02-02. PMID:38306047. |
this age-related neurodegenerative disease is characterized by an early decline in episodic and spatial memory associated with progressive disruption of the hippocampal functioning. |
2024-02-02 |
2024-02-04 |
mouse |
| Israel Garcia-Carachure, Omar Lira, Anapaula Themann, Minerva Rodriguez, Francisco J Flores-Ramirez, Mary Kay Lobo, Sergio D Iñigue. Sex-Specific Alterations in Spatial Memory and Hippocampal AKT-mTOR Signaling in Adult Mice Pre-exposed to Ketamine and/or Psychological Stress During Adolescence. Biological psychiatry global open science. vol 4. issue 1. 2024-02-01. PMID:38298791. |
sex-specific alterations in spatial memory and hippocampal akt-mtor signaling in adult mice pre-exposed to ketamine and/or psychological stress during adolescence. |
2024-02-01 |
2024-02-03 |
mouse |
| Jena B Hales, Larissa Olivas, Daniela Abouchedid, Rachel E Blase. Contribution of the medial entorhinal cortex to performance on the Traveling Salesperson Problem in rats. Behavioural brain research. 2024-01-28. PMID:38281708. |
previous research found that hippocampal lesions in rats impaired tsp task performance, particularly on measures of spatial memory. |
2024-01-28 |
2024-01-31 |
human |
| Jena B Hales, Larissa Olivas, Daniela Abouchedid, Rachel E Blase. Contribution of the medial entorhinal cortex to performance on the Traveling Salesperson Problem in rats. Behavioural brain research. 2024-01-28. PMID:38281708. |
our results showed that, similar to rats with hippocampal lesions, mec-lesioned rats were impaired on measures of spatial memory, but not spatial decision-making, with greatest impairments on configurations requiring a global navigational strategy for selecting the optimal route. |
2024-01-28 |
2024-01-31 |
human |
| In-Young Choi, Jung-Ho Cha, Seong Yun Kim, Jenny Hsieh, Kyung-Ok Ch. Seizure-induced LIN28A disrupts pattern separation via aberrant hippocampal neurogenesis. JCI insight. vol 9. issue 1. 2024-01-09. PMID:38193536. |
prolonged seizures can disrupt stem cell behavior in the adult hippocampus, an important brain structure for spatial memory. |
2024-01-09 |
2024-01-10 |
mouse |