| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ewa Niedzielska-Andres, Lucyna Pomierny-Chamioło, Michał Andres, Maria Walczak, Lori A Knackstedt, Małgorzata Filip, Edmund Przegalińsk. Cocaine use disorder: A look at metabotropic glutamate receptors and glutamate transporters. Pharmacology & therapeutics. vol 221. 2021-08-26. PMID:33359590. |
the present review summarizes the changes in glutamate levels in the reward system (the prefrontal cortex, nucleus accumbens, dorsal striatum, hippocampus, and ventral tegmental area) observed in preclinical studies at different stages of cocaine exposure and withdrawal as well as after reinstatement of cocaine-seeking behavior. |
2021-08-26 |
2023-08-13 |
Not clear |
| Caroline E Strong, Mohamed Kabba. Neural Mechanisms Underlying the Rewarding and Therapeutic Effects of Ketamine as a Treatment for Alcohol Use Disorder. Frontiers in behavioral neuroscience. vol 14. 2021-07-08. PMID:33362485. |
to do this, the focus will be on reward-related brain regions such as the nucleus accumbens (nac), dorsal striatum, prefrontal cortex (pfc), hippocampus, and ventral tegmental area (vta) to understand how acute vs. chronic exposure will alter reward signaling over time. |
2021-07-08 |
2023-08-13 |
human |
| Serena Banu Gumusoglu, Akanksha Sri Satya Chilukuri, Benjamin Wen Qing Hing, Sabrina Marie Scroggins, Sreelekha Kundu, Jeremy Anton Sandgren, Mark Kharim Santillan, Donna Ann Santillan, Justin Lewis Grobe, Hanna Elizabeth Steven. Altered offspring neurodevelopment in an arginine vasopressin preeclampsia model. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33510137. |
adult avp-exposed females had increased caudate-putamen volume, increased caudate-putamen cell number, and decreased excitatory synapse density in hippocampal dentate gyrus (dg), ca1, and ca3. |
2021-06-28 |
2023-08-13 |
mouse |
| Matthew R J Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R Daoust, Marc F Joanisse, Deanna M Barch, Elizabeth P Hayde. Orbitofrontal cortex grey matter volume is related to children's depressive symptoms. NeuroImage. Clinical. vol 28. 2021-06-25. PMID:32889399. |
adults with a history of depression show distinct patterns of grey matter volume (gmv) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. |
2021-06-25 |
2023-08-13 |
Not clear |
| Kaili Du, Zhuoyi Wang, Huimin Zhang, Yaofang Zhang, Hongliang Su, Zhiwen Wei, Chao Zhang, Keming Yun, Bin Con. Levo-tetrahydropalmatine attenuates the acquisition of fentanyl-induced conditioned place preference and the changes in ERK and CREB phosphorylation expression in mice. Neuroscience letters. vol 756. 2021-06-22. PMID:34029649. |
western blot assays were used to dissect the accompanying changes in the phosphorylation of extracellular signal-regulated kinase (erk) and camp response element binding protein (creb) in related brain regions, including the hippocampus (hip), caudate putamen (cpu), prefrontal cortex (pfc), and nucleus accumbens (nac), which may mediate the effects of l-thp on fentanyl-induced cpp. |
2021-06-22 |
2023-08-13 |
mouse |
| Tharini Ketharanathan, Avril Pereira, Udani Reets, David Walker, Suresh Sundra. Brain changes in NF-κB1 and epidermal growth factor system markers at peri-pubescence in the spiny mouse following maternal immune activation. Psychiatry research. vol 295. 2021-06-21. PMID:33229121. |
after mid-gestation mia prepubescent offspring showed elevated nf-κb1 protein in nucleus accumbens, decreased egfr in caudate putamen and a trend for increased pi3k-110δ in ventral hippocampus. |
2021-06-21 |
2023-08-13 |
mouse |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Milo Grotell, Bjørnar den Hollander, Aaro Jalkanen, Essi Törrönen, Jouni Ihalainen, Elena de Miguel, Mateusz Dudek, Mikko I Kettunen, Petri Hyytiä, Markus M Forsberg, Esko Kankuri, Esa R Korp. Alcohol Co-Administration Changes Mephedrone-Induced Alterations of Neuronal Activity. Frontiers in pharmacology. vol 12. 2021-05-18. PMID:33995109. |
these effects were most profound in brain regions which are known to have high dopamine and serotonin activities including hippocampus, nucleus accumbens and caudate-putamen. |
2021-05-18 |
2023-08-13 |
rat |
| Chiomah Ezeomah, Kathryn A Cunningham, Sonja J Stutz, Robert G Fox, Natalya Bukreyeva, Kelly T Dineley, Slobodan Paessler, Irma E Cisnero. Fentanyl self-administration impacts brain immune responses in male Sprague-Dawley rats. Brain, behavior, and immunity. vol 87. 2021-04-27. PMID:32165150. |
several innate immune markers, as well as opioid receptors (ors) and intracellular pattern recognition receptors (prrs), were interrogated within nodes of the neurocircuitry involved in oud processes, including the prefrontal cortex (pfc), nucleus accumbens (nac), caudate putamen (cpu), hippocampus (hip) and midbrain (mb). |
2021-04-27 |
2023-08-13 |
rat |
| Yosef Avchalumov, Chitra D Mandya. Synaptic Plasticity and its Modulation by Alcohol. Brain plasticity (Amsterdam, Netherlands). vol 6. issue 1. 2021-03-10. PMID:33680849. |
in the first part of this review, we will briefly discuss the mechanisms underlying long term synaptic plasticity in the dorsal striatum, neocortex and the hippocampus. |
2021-03-10 |
2023-08-13 |
Not clear |
| Stefan Koelsc. A coordinate-based meta-analysis of music-evoked emotions. NeuroImage. vol 223. 2021-03-08. PMID:32898679. |
the results of an activation likelihood estimation (ale) indicate large clusters in a range of structures, including amygdala, anterior hippocampus, auditory cortex, and numerous structures of the reward network (ventral and dorsal striatum, anterior cingulate cortex, orbitofrontal cortex, secondary somatosensory cortex). |
2021-03-08 |
2023-08-13 |
human |
| A Sánchez-González, I Oliveras, C Río-Álamos, M A Piludu, C Gerbolés, C Tapias-Espinosa, A Tobeña, S Aznar, A Fernández-Terue. Dissociation between schizophrenia-relevant behavioral profiles and volumetric brain measures after long-lasting social isolation in Roman rats. Neuroscience research. vol 155. 2021-02-23. PMID:31306676. |
the aim here was to further investigate the neuroanatomical effects of the isolation rearing, estimated through volume differences in medial prefrontal cortex (mpfc), dorsal striatum (dst) and hippocampus (hpc). |
2021-02-23 |
2023-08-13 |
rat |
| Xixi Yang, Yichong Wen, Yuxiang Zhang, Feifei Gao, Jingsi Yang, Zhuojin Yang, Chunxia Ya. Dynamic Changes of Cytoskeleton-Related Proteins Within Reward-Related Brain Regions in Morphine-Associated Memory. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584180. |
compared with the nac and dorsal hippocampus, dynamic changes in the medial prefrontal cortex (mpfc) and caudate putamen (cpu) were not very significant. |
2021-02-16 |
2023-08-13 |
mouse |
| Jarid Goodman, Mason McClay, Joseph E Dunsmoo. Threat-induced modulation of hippocampal and striatal memory systems during navigation of a virtual environment. Neurobiology of learning and memory. vol 168. 2021-01-13. PMID:31918021. |
the hippocampus is important for encoding and retrieving allocentric spatial cognitive maps, while the dorsal striatum mediates procedural memories based on stimulus-response (s-r) associations. |
2021-01-13 |
2023-08-13 |
human |
| Christoffer J Gahnstrom, Hugo J Spier. Striatal and hippocampal contributions to flexible navigation in rats and humans. Brain and neuroscience advances. vol 4. 2021-01-12. PMID:33426302. |
we highlight that future research should explore the following: (1) investigate neural responses during spatial navigation via a biophysically plausible framework explained by reinforcement learning models and (2) observe the interaction between cortical areas and both the dorsal striatum and hippocampus during flexible navigation. |
2021-01-12 |
2023-08-13 |
human |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior. vol 190. 2021-01-07. PMID:32084491. |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-08-13 |
mouse |
| Elisabetta F Buonaguro, Sara Morley-Fletcher, Camilla Avagliano, Licia Vellucci, Felice Iasevoli, Hammou Bouwalerh, Gilles Van Camp, Ferdinando Nicoletti, Stefania Maccari, Andrea de Bartolomei. Glutamatergic postsynaptic density in early life stress programming: Topographic gene expression of mGlu5 receptors and Homer proteins. Progress in neuro-psychopharmacology & biological psychiatry. vol 96. 2021-01-04. PMID:31404590. |
to this end, we investigated unconditioned behavioral response using the light/dark box test, as well as the expression of psd genes (homer1a, homer1b, and grm5), in the medial prefrontal cortex, cortex, caudate-putamen, amygdala, and dorsal hippocampus. |
2021-01-04 |
2023-08-13 |
rat |
| Gang Chen, Tao Li, Jing Xiao, Jing Wang, Qing Shang, Hongyan Qian, Chuchu Qiao, Ping Zhang, Teng Chen, Xinshe Li. Ifenprodil Attenuates Methamphetamine-Induced Behavioral Sensitization Through the GluN2B-PP2A-AKT Cascade in the Dorsal Striatum of Mice. Neurochemical research. vol 45. issue 4. 2020-12-11. PMID:31981057. |
in this study, we measured the level of phosphorylated (p-) glun2b (serine; ser 1303), pp2a/b (a regulatory subunit of pp2a), and pp2a/c (a catalytic subunit of pp2a) in different brain regions such as the prefrontal cortex (pfc), nucleus accumbens (nac), dorsal striatum (ds), and hippocampus (hip). |
2020-12-11 |
2023-08-13 |
mouse |
| Hongliang Su, Tingting Sun, Xiao Wang, Yan Du, Na Zhao, Jie Zhu, Jiangwei Yan, Teng Chen, Keming Yu. Levo-tetrahydropalmatine attenuates methamphetamine reward behavior and the accompanying activation of ERK phosphorylation in mice. Neuroscience letters. vol 714. 2020-12-07. PMID:31398456. |
we then dissected the underlying molecular mechanisms of l-thp in modulating meth-induced cpp by evaluating accompanying changes in expression of phosphorylated extracellular signal-regulated kinase (p-erk) in reward-relevant brain regions, including nucleus accumbens (nac), prefrontal cortex (pfc), caudate putamen (cpu), and hippocampus (hip), which may mediate the effects of l-thp on meth-induced cpp. |
2020-12-07 |
2023-08-13 |
mouse |
| Liu Yang, Yawen Su, Fannv Guo, Handi Zhang, Yinglin Zhao, Qinjun Huang, Haiyun X. Deep rTMS Mitigates Behavioral and Neuropathologic Anomalies in Cuprizone-Exposed Mice Through Reducing Microglial Proinflammatory Cytokines. Frontiers in integrative neuroscience. vol 14. 2020-12-01. PMID:33250722. |
compared to the cnt group, mice in cpz and cpz + sham groups showed deficits in social recognition and spatial working memory as well as anxiety-like behavior, in addition to myelin breakdown and ol loss in the corpus callosum (cc), caudate putamen, cerebral cortex, and hippocampus of the brain. |
2020-12-01 |
2023-08-13 |
mouse |