| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
the role of serotonin (5-ht)1b receptors in the mechanism of action of selective serotonin re-uptake inhibitors (ssri) was studied by using intracerebral in vivo microdialysis in conscious, freely moving wild-type and 5-ht1b receptor knockout (ko 5-ht1b) mice in order to compare the effects of chronic administration of paroxetine via osmotic minipumps (1 mg per kg per day for 14 days) on extracellular 5-ht levels ([5-ht]ext) in the medial prefrontal cortex and ventral hippocampus. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
basal [5-ht]ext values in the medial prefrontal cortex and ventral hippocampus, approximately 20 h after removing the minipump, were not altered by chronic paroxetine treatment in both genotypes. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
by using the zero net flux method of quantitative microdialysis in the medial prefrontal cortex and ventral hippocampus of wild-type and ko 5-ht1b mice, we found that basal [5-ht]ext and the extraction fraction of 5-ht were similar in the medial prefrontal cortex and ventral hippocampus of both genotypes, suggesting that no compensatory response to the constitutive deletion of the 5-ht1b receptor involving changes in 5-ht uptake capacity occurred in vivo. |
2003-08-26 |
2023-08-12 |
mouse |
| A M Gardier, D J David, G Jego, C Przybylski, C Jacquot, S Durier, B Gruwez, E Douvier, P Beauverie, N Poisson, R Hen, M Bouri. Effects of chronic paroxetine treatment on dialysate serotonin in 5-HT1B receptor knockout mice. Journal of neurochemistry. vol 86. issue 1. 2003-08-26. PMID:12807420. |
these data suggest that there are differences between the ventral hippocampus and medial prefrontal cortex in activation of terminal 5-ht1b autoreceptors and their role in regulating dialysate 5-ht levels. |
2003-08-26 |
2023-08-12 |
mouse |
| Kerrie L Thomas, Mercedes Arroyo, Barry J Everit. Induction of the learning and plasticity-associated gene Zif268 following exposure to a discrete cocaine-associated stimulus. The European journal of neuroscience. vol 17. issue 9. 2003-07-16. PMID:12752796. |
in rats that had self-administered drug, the cocaine-conditioned stimulus (cs) increased zif268 expression in neurons of the ventral tegmental area, nucleus accumbens core and shell, and basal nucleus of the amygdala but not hippocampus, prelimbic area of the medial prefrontal cortex or amygdala central nucleus. |
2003-07-16 |
2023-08-12 |
rat |
| J Douglas Bremner, Meena Vythilingam, Eric Vermetten, Steven M Southwick, Thomas McGlashan, Lawrence H Staib, Robert Soufer, Dennis S Charne. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biological psychiatry. vol 53. issue 10. 2003-07-07. PMID:12742675. |
patients with childhood abuse-related posttraumatic stress disorder (ptsd) have alterations in both declarative and nondeclarative memory function, and imaging studies in ptsd have demonstrated changes in function during stimulation of trauma-specific memories in hippocampus, medial prefrontal cortex, and cingulate. |
2003-07-07 |
2023-08-12 |
Not clear |
| K A Helm, J-S Han, M Gallaghe. Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat. Neuroscience. vol 115. issue 3. 2003-04-07. PMID:12435415. |
effects of cholinergic lesions produced by infusions of 192 igg-saporin on glucocorticoid receptor mrna expression in hippocampus and medial prefrontal cortex of the rat. |
2003-04-07 |
2023-08-12 |
rat |
| K A Helm, J-S Han, M Gallaghe. Effects of cholinergic lesions produced by infusions of 192 IgG-saporin on glucocorticoid receptor mRNA expression in hippocampus and medial prefrontal cortex of the rat. Neuroscience. vol 115. issue 3. 2003-04-07. PMID:12435415. |
the current study investigated the possibility that a loss of cholinergic support from cells in the basal forebrain, a hallmark of aging, contributes to the selective age-related loss of glucocorticoid receptor mrna expression at cholinoceptive target sites that include the hippocampus and medial prefrontal cortex. |
2003-04-07 |
2023-08-12 |
rat |
| Inah Lee, Raymond P Kesne. Time-dependent relationship between the dorsal hippocampus and the prefrontal cortex in spatial memory. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 4. 2003-03-24. PMID:12598640. |
here we report that the dorsal hippocampus and the medial prefrontal cortex process short-term spatial memory in parallel, serving as a compensatory mechanism for each other. |
2003-03-24 |
2023-08-12 |
human |
| Réne Garci. Stress, synaptic plasticity, and psychopathology. Reviews in the neurosciences. vol 13. issue 3. 2003-02-07. PMID:12405224. |
this review focuses on alterations of synaptic efficacy in the hippocampus, the lateral septum, and the medial prefrontal cortex that mimic the pathophysiology of depression and post-traumatic stress disorder. |
2003-02-07 |
2023-08-12 |
Not clear |
| J D Bremner, R Soufer, G McCarthy, R Delaney, L H Staib, J S Duncan, D S Charne. Gender differences in cognitive and neural correlates of remembrance of emotional words. Psychopharmacology bulletin. vol 35. issue 3. 2002-11-14. PMID:12397879. |
during retrieval of emotional words (but not neutral words) there was a different pattern of activation among the women compared with the men, with greater activation in bilateral posterior hippocampus and cerebellum, and decreased activity in medial prefrontal cortex, which are brain areas previously implicated in emotion. |
2002-11-14 |
2023-08-12 |
human |
| J Douglas Bremne. Neuroimaging of childhood trauma. Seminars in clinical neuropsychiatry. vol 7. issue 2. 2002-10-29. PMID:11953934. |
functional neuroimaging studies are consistent with alteration in function and structure of medial prefrontal cortex and hippocampus in patients with childhood sexual trauma and ptsd. |
2002-10-29 |
2023-08-12 |
Not clear |
| Leo Gotoh, Noriko Kawanami, Tatsuo Nakahara, Hisao Hondo, Keisuke Motomura, Eiko Ohta, Izumi Kanchiku, Toshihide Kuroki, Makoto Hirano, Hideyuki Uchimur. Effects of the adenosine A(1) receptor agonist N(6)-cyclopentyladenosine on phencyclidine-induced behavior and expression of the immediate-early genes in the discrete brain regions of rats. Brain research. Molecular brain research. vol 100. issue 1-2. 2002-08-13. PMID:12008016. |
pcp increased the mrna levels of c-fos and jun b in the medial prefrontal cortex, nucleus accumbens and posterior cingulate cortex, while leaving the striatum and hippocampus unaffected. |
2002-08-13 |
2023-08-12 |
rat |
| Hisatsugu Miyata, Kiyoshi Ando, Tomoji Yanagit. Brain regions mediating the discriminative stimulus effects of nicotine in rats. Annals of the New York Academy of Sciences. vol 965. 2002-08-02. PMID:12105111. |
substitution tests with nicotine administered into the medial prefrontal cortex, nucleus accumbens, and ventral tegmental area, all of which are located on the mesolimbocortical dopaminergic neurons, and into the dorsal hippocampus and medial habenular nucleus, which possess high densities of nicotinic cholinergic receptors, were conducted in rats trained to discriminate nicotine (0.5 mg/kg s.c.) from saline solution in a two-lever, food-reinforced, operant task. |
2002-08-02 |
2023-08-12 |
rat |
| A Adell, P Celada, F Artiga. The role of 5-HT1B receptors in the regulation of serotonin cell firing and release in the rat brain. Journal of neurochemistry. vol 79. issue 1. 2001-10-25. PMID:11595769. |
the intravenous administration of the brain-penetrant selective 5-ht1b receptor agonist cp-94,253 (0.5-2.0 mg/kg) to anesthetized rats decreased dialysate 5-ht in dorsal hippocampus and globus pallidus, increased it in mnr and left it unaltered in the dr and medial prefrontal cortex. |
2001-10-25 |
2023-08-12 |
rat |
| S Hume, E Hirani, J Opacka-Juffry, R Myers, C Townsend, V Pike, P Grasb. Effect of 5-HT on binding of [(11)C] WAY 100635 to 5-HT(IA) receptors in rat brain, assessed using in vivo microdialysis nd PET after fenfluramine. Synapse (New York, N.Y.). vol 41. issue 2. 2001-08-23. PMID:11400181. |
resulted in a approximately 5-fold increase in extracellular 5-ht in medial prefrontal cortex and a approximately 15-fold increase in lateral hippocampus, maximal at approximately 40 min after injection. |
2001-08-23 |
2023-08-12 |
human |
| J P de Bruin, M P Moita, H M de Brabander, R N Jooste. Place and response learning of rats in a Morris water maze: differential effects of fimbria fornix and medial prefrontal cortex lesions. Neurobiology of learning and memory. vol 75. issue 2. 2001-06-14. PMID:11222058. |
wistar rats with hippocampal damage (inflicted by a bilateral lesion of the fimbria fornix), rats with damage to the medial prefrontal cortex, and control-operated rats were examined for their performance in either one of two different spatial tasks in a morris water maze, a place learning task (requiring a locale system), or a response learning task (requiring a taxon system). |
2001-06-14 |
2023-08-12 |
rat |
| F I Tarazi, K Zhang, R J Baldessarin. Long-term effects of olanzapine, risperidone, and quetiapine on dopamine receptor types in regions of rat brain: implications for antipsychotic drug treatment. The Journal of pharmacology and experimental therapeutics. vol 297. issue 2. 2001-05-21. PMID:11303062. |
olanzapine and risperidone, but not quetiapine, significantly increased d(2) binding in medial prefrontal cortex (mpc; 67% and 34%), caudate-putamen (cpu; average 42%, 25%), nucleus accumbens (nac; 37%, 28%), and hippocampus (hip; 53%, 30%). |
2001-05-21 |
2023-08-12 |
rat |
| J M Casanovas, O Berton, P Celada, F Artiga. In vivo actions of the selective 5-HT1A receptor agonist BAY x 3702 on serotonergic cell firing and release. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997727. |
in microdialysis experiments, bay x 3702 (10-100 microg/ kg s.c.) reduced dose-dependently the 5-ht output in the dorsal and median raphe (mnr) nucleus, dorsal hippocampus (dhpc) and medial prefrontal cortex (mpfc) in a regionally selective manner. |
2001-01-05 |
2023-08-12 |
rat |
| T R Franklin, J P Druha. Involvement of the nucleus accumbens and medial prefrontal cortex in the expression of conditioned hyperactivity to a cocaine-associated environment in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 6. 2001-01-04. PMID:11063919. |
this study examined the roles of the nucleus accumbens (nac), medial prefrontal cortex, basolateral amygdala, and ventral subiculum of the hippocampus in the expression of pavlovian conditioned hyperactivity responses to cocaine-related stimuli. |
2001-01-04 |
2023-08-12 |
rat |