All Relations between hippocampus and orbital frontal cortex

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Qi Liu, Lizhou Chen, Fei Li, Ying Chen, Lanting Guo, Qiyong Gong, Xiaoqi Huan. [Voxel-Based Morphometry in Medicated-naive Boys with Attention-deficit/hyperactivity Disorder(ADHD)]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 33. issue 3. 2018-05-24. PMID:29709154. attention-deficit/hyperactivity disorder(adhd)is one of the most common neuro-developmental disorders occurring in childhood,characterized by symptoms of age-inappropriate inattention,hyperactivity/impulsivity,and the prevalence is higher in boys.although gray matter volume deficits have been frequently reported for adhd children via structural magnetic resonance imaging,few of them had specifically focused on male patients.the present study aimed to explore the alterations of gray matter volumes in medicated-naive boys with adhd via a relatively new voxel-based morphometry technique.according to the criteria of dsm-iv-tr,43medicated-naive adhd boys and 44age-matched healthy boys were recruited.the magnetic resonance image(mri)scan was performed via a 3t mri system with three-dimensional(3d)spoiled gradient recalled echo(spgr)sequence.voxel-based morphometry with diffeomorphic anatomical registration through exponentiated lie algebra in spm8 was used to preprocess the3dt1-weighted images.to identify gray matter volume differences between the adhd and the controls,voxelbased analysis of whole brain gray matter volumes between two groups were done via two sample t-test in spm8 with age as covariate,threshold at p<0.001.finally,compared to the controls,significantly reduced gray matter volumes were identified in the right orbitofrontal cortex(peak coordinates[-2,52,-25],t=4.01),and bilateral hippocampus(left:peak coordinates[14,0,-18],t=3.61;right:peak coordinates[-14,15,-28],t=3.64)of adhd boys.our results demonstrated obvious reduction of whole brain gray matter volumes in right orbitofrontal cortex and bilateral hippocampus in boys with adhd.this suggests that the abnormalities of prefrontal-hippocampus circuit may be the underlying cause of the cognitive dysfunction and abnormal behavioral inhibition in medicatednaive boys with adhd. 2018-05-24 2023-08-13 Not clear
Selene Cansino, Patricia Trejo-Morales, Cinthya Estrada-Manilla, Erick Humberto Pasaye-Alcaraz, Erika Aguilar-Castañeda, Perla Salgado-Lujambio, Ana Luisa Sosa-Orti. Effective connectivity during successful and unsuccessful recollection in young and old adults. Neuropsychologia. vol 103. 2018-04-24. PMID:28733247. in particular, we analyzed a recollection network that is characterized by its susceptibility to aging effects by middle age or later, which is comprised of the occipital cortex, hippocampus and orbitofrontal cortex. 2018-04-24 2023-08-13 human
Selene Cansino, Patricia Trejo-Morales, Cinthya Estrada-Manilla, Erick Humberto Pasaye-Alcaraz, Erika Aguilar-Castañeda, Perla Salgado-Lujambio, Ana Luisa Sosa-Orti. Effective connectivity during successful and unsuccessful recollection in young and old adults. Neuropsychologia. vol 103. 2018-04-24. PMID:28733247. dynamic causal modeling and bayesian model selection revealed that subsequent recollection during encoding and recollection during retrieval modulated the influence of the orbitofrontal cortex on the hippocampus in both age groups; this particular connectivity was not modulated by unsuccessful encoding in either group. 2018-04-24 2023-08-13 human
Selene Cansino, Patricia Trejo-Morales, Cinthya Estrada-Manilla, Erick Humberto Pasaye-Alcaraz, Erika Aguilar-Castañeda, Perla Salgado-Lujambio, Ana Luisa Sosa-Orti. Effective connectivity during successful and unsuccessful recollection in young and old adults. Neuropsychologia. vol 103. 2018-04-24. PMID:28733247. the findings revealed that the orbitofrontal cortex influences processes in the hippocampus to ensure successful recollection, and aging alters the recollection network by engaging non-specialized connections. 2018-04-24 2023-08-13 human
Sherri B Briggs, Ashley M Blouin, Erica J Young, Gavin Rumbaugh, Courtney A Mille. Memory disrupting effects of nonmuscle myosin II inhibition depend on the class of abused drug and brain region. Learning & memory (Cold Spring Harbor, N.Y.). vol 24. issue 2. 2018-02-12. PMID:28096495. unlike in the amygdala, methamphetamine-associated memory storage was not disrupted by nmiii in the hippocampus, nucleus accumbens, or orbitofrontal cortex. 2018-02-12 2023-08-13 Not clear
Vishnu P Murty, Kevin S LaBar, R Alison Adcoc. Distinct medial temporal networks encode surprise during motivation by reward versus punishment. Neurobiology of learning and memory. vol 134 Pt A. 2018-02-09. PMID:26854903. further, we found that reward motivation facilitated hippocampal coupling with ventromedial pfc, whereas punishment motivation facilitated parahippocampal cortical coupling with orbitofrontal cortex. 2018-02-09 2023-08-13 human
Suzanne N Avery, Jennifer Urbano Blackfor. Slow to warm up: the role of habituation in social fear. Social cognitive and affective neuroscience. vol 11. issue 11. 2017-11-08. PMID:27445209. higher social fearfulness was associated with slower habituation across regions of the social brain, including the hippocampus, amygdala, ventromedial prefrontal cortex, medial orbitofrontal cortex, fusiform face area, primary visual cortex, and extrastriate visual cortex. 2017-11-08 2023-08-13 Not clear
M M Darby, R H Yolken, S Sabunciya. Consistently altered expression of gene sets in postmortem brains of individuals with major psychiatric disorders. Translational psychiatry. vol 6. issue 9. 2017-11-07. PMID:27622934. we then identified genes and canonical pathway gene sets with significantly altered expression in schizophrenia and bipolar disorder in the hippocampus and in schizophrenia, bipolar disorder and major depression in the orbitofrontal cortex. 2017-11-07 2023-08-13 Not clear
Pascal Molenberghs, Fynn-Mathis Trautwein, Anne Böckler, Tania Singer, Philipp Kansk. Neural correlates of metacognitive ability and of feeling confident: a large-scale fMRI study. Social cognitive and affective neuroscience. vol 11. issue 12. 2017-11-03. PMID:27445213. moreover, the feeling of confidence about one's choices was associated with an increase of activation in reward, memory and motor related areas including bilateral striatum and hippocampus, while less confidence was associated with activation in areas linked with negative affect and uncertainty, including dorsomedial prefrontal and bilateral orbitofrontal cortex. 2017-11-03 2023-08-13 human
Dario Grossi, Mariachiara Longarzo, Mario Quarantelli, Elena Salvatore, Carlo Cavaliere, Paolofabrizio De Luca, Luigi Trojano, Marco Aiell. Altered functional connectivity of interoception in illness anxiety disorder. Cortex; a journal devoted to the study of the nervous system and behavior. vol 86. 2017-10-09. PMID:27871020. scores on a questionnaire for interoceptive awareness were significantly correlated with higher fc between right hippocampus and nucleus accumbens bilaterally, and with higher connectivity between left anterior cingulate cortex (acc) and left orbitofrontal cortex (ofc). 2017-10-09 2023-08-13 Not clear
Andrew M Wikenheiser, Yasmin Marrero-Garcia, Geoffrey Schoenbau. Suppression of Ventral Hippocampal Output Impairs Integrated Orbitofrontal Encoding of Task Structure. Neuron. vol 95. issue 5. 2017-09-28. PMID:28823726. the hippocampus and orbitofrontal cortex (ofc) both make important contributions to decision making and other cognitive processes. 2017-09-28 2023-08-13 rat
Andrew M Wikenheiser, Geoffrey Schoenbau. Over the river, through the woods: cognitive maps in the hippocampus and orbitofrontal cortex. Nature reviews. Neuroscience. vol 17. issue 8. 2017-05-25. PMID:27256552. the hippocampus and the orbitofrontal cortex (ofc) both have important roles in cognitive processes such as learning, memory and decision making. 2017-05-25 2023-08-13 Not clear
Judith K Daniels, Eric Vermette. Odor-induced recall of emotional memories in PTSD-Review and new paradigm for research. Experimental neurology. vol 284. issue Pt B. 2017-05-04. PMID:27511295. brain areas mediating smell memory including orbitofrontal cortex and other parts of medial prefrontal cortex, hippocampus and amygdala, have been implicated in learning and memory and are part of a neural circuitry that is involved in ptsd. 2017-05-04 2023-08-13 human
Laura Koenders, Janna Cousijn, Wilhelmina A M Vingerhoets, Wim van den Brink, Reinout W Wiers, Carin J Meijer, Marise W J Machielsen, Dick J Veltman, Anneke E Goudriaan, Lieuwe de Haa. Grey Matter Changes Associated with Heavy Cannabis Use: A Longitudinal sMRI Study. PloS one. vol 11. issue 5. 2017-04-06. PMID:27224247. grey matter volumes (orbitofrontal cortex, anterior cingulate cortex, insula, striatum, thalamus, amygdala, hippocampus and cerebellum) were estimated using the software package spm (vbm-8 module). 2017-04-06 2023-08-13 Not clear
R Mychasiuk, A Muhammad, B Kol. Chronic stress induces persistent changes in global DNA methylation and gene expression in the medial prefrontal cortex, orbitofrontal cortex, and hippocampus. Neuroscience. vol 322. 2016-12-13. PMID:26946265. chronic stress is associated with a plethora of cognitive symptoms such as emotional dysregulation and impaired executive function that have been attributed to modifications in neuroanatomy in the orbitofrontal cortex (ofc), medial prefrontal cortex (mpfc), and hippocampus (hpc). 2016-12-13 2023-08-13 rat
Nicola Dusi, Stefano Barlati, Antonio Vita, Paolo Brambill. Brain Structural Effects of Antidepressant Treatment in Major Depression. Current neuropharmacology. vol 13. issue 4. 2016-08-09. PMID:26412065. altered brain structures in depressive disorder have been particularly located in the prefrontal cortex (medial prefrontal cortex and orbitofrontal cortex, ofc) and medial temporal cortex areas (hippocampus). 2016-08-09 2023-08-13 Not clear
Erie D Boorman, Vani G Rajendran, Jill X O'Reilly, Tim E Behren. Two Anatomically and Computationally Distinct Learning Signals Predict Changes to Stimulus-Outcome Associations in Hippocampus. Neuron. vol 89. issue 6. 2016-08-02. PMID:26948895. here we report two anatomically and computationally distinct learning signals in lateral orbitofrontal cortex (lofc) and the dopaminergic ventral midbrain (vm) that predict trial-by-trial changes to a basic internal model in hippocampus. 2016-08-02 2023-08-13 Not clear
Meneka K Sidhu, Jason Stretton, Gavin P Winston, Andrew W McEvoy, Mark Symms, Pamela J Thompson, Matthias J Koepp, John S Dunca. Memory network plasticity after temporal lobe resection: a longitudinal functional imaging study. Brain : a journal of neurology. vol 139. issue Pt 2. 2016-06-30. PMID:26754787. left anterior hippocampal and orbitofrontal cortex activations correlated with improvements in both design and verbal learning 12 months postoperatively. 2016-06-30 2023-08-13 human
New-Fei Ho, Joanna S X Chong, Hui Li Koh, Eleni Koukouna, Tih-Shih Lee, Daniel Fung, Choon Guan Lim, Juan Zho. Intrinsic Affective Network Is Impaired in Children with Attention-Deficit/Hyperactivity Disorder. PloS one. vol 10. issue 9. 2016-06-17. PMID:26406311. in this study, we use resting-state functional magnetic resonance imaging to test the hypothesis of diminished functional integration within the affective/limbic network (which includes the amygdala, hippocampus, subgenual cingulate cortex, orbitofrontal cortex and nucleus accumbens) of children with adhd, which is associated with their behavioral measures of emotional control deficits. 2016-06-17 2023-08-13 human
Andrew R Abela, Yiran Duan, Yogita Chudasam. Hippocampal interplay with the nucleus accumbens is critical for decisions about time. The European journal of neuroscience. vol 42. issue 5. 2016-06-01. PMID:26121594. the nucleus accumbens, a recipient of direct projections from both the hippocampus and orbitofrontal cortex, is known to contribute to these aspects of decision-making. 2016-06-01 2023-08-13 human