| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xue-Ping Yang, Dan-Dai, Ruo-Xia Chen, Yu-Xuan Li, Xue Rui Lv, Yun L. The expression of ProBDNF and its high affinity receptor P75NTR in the neurons of emotion-related brain regions of post-stroke depression rats. Brain research. 2024-02-29. PMID:38423239. |
to investigate the expression of the precursor of brain-derived neurotrophic factor (probdnf) and its high-affinity receptor p75ntr in neurons of emotion-related brain areas (prefrontal cortex, hippocampus, and amygdala) in rats with post-stroke depression (psd), and to explore the expression levels of probdnf and p75ntr in neurons of emotion-related brain areas by injecting tissue plasminogen activator (t-pa) into the lateral ventricle of psd rats, this significantly improved the stress-induced depression-like behavior,thus further validating the above results. |
2024-02-29 |
2024-03-03 |
rat |
| Shuyang Yao, Arvid Harder, Fahimeh Darki, Yu-Wei Chang, Ang Li, Kasra Nikouei, Giovanni Volpe, Johan N Lundström, Jian Zeng, Naomi Wray, Yi Lu, Patrick F Sullivan, Jens Hjerling-Leffle. Connecting genomic results for psychiatric disorders to human brain cell types and regions reveals convergence with functional connectivity. medRxiv : the preprint server for health sciences. 2024-02-27. PMID:38410450. |
using functional mri connectivity from cases with schizophrenia and neurotypical controls, we identified brain networks that distinguished cases from controls that also confirmed involvement of the central and lateral amygdala, hippocampal body, and prefrontal cortex. |
2024-02-27 |
2024-03-02 |
mouse |
| Michael L Mack, Bradley C Love, Alison R Presto. Distinct hippocampal mechanisms support concept formation and updating. bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405893. |
hippocampus additionally showed distinct patterns of functional coactivation with ventromedial prefrontal cortex and angular gyrus during memory creation and premotor cortex during memory updating. |
2024-02-26 |
2024-02-28 |
Not clear |
| Guochun Yang, Jiefeng Jian. Cost-benefit Tradeoff Mediates the Rule- to Memory-based Transition during Practice. bioRxiv : the preprint server for biology. 2024-02-26. PMID:38405946. |
lastly, strategy transition is related to neural representation change in the dorsolateral prefrontal cortex and pattern separation in the ventromedial prefrontal cortex and the hippocampus. |
2024-02-26 |
2024-02-28 |
human |
| Mariélia B L de Freitas, Licia P Luna, Márcia Beatriz, Romulo Kunrath Pinto, Candida H Lopes Alves, Lays Bittencourt, Antônio E Nardi, Viola Oertel, André B Veras, David Freitas de Lucena, Gilberto Sousa Alve. Resting-state fMRI is associated with trauma experiences, mood and psychosis in Afro-descendants with bipolar disorder and schizophrenia. Psychiatry research. Neuroimaging. vol 340. 2024-02-26. PMID:38408419. |
bipolar disorder (bd) and schizophrenia (scz) may exhibit functional abnormalities in several brain areas, including the medial temporal and prefrontal cortex and hippocampus; however, a less explored topic is how brain connectivity is linked to premorbid trauma experiences and clinical features in non-caucasian samples of scz and bd. |
2024-02-26 |
2024-03-02 |
Not clear |
| Bharti Biswas, Valsamma Eapen, Margaret J Morris, Nicole M Jone. Combined Effect of Maternal Separation and Early-Life Immune Activation on Brain and Behaviour of Rat Offspring. Biomolecules. vol 14. issue 2. 2024-02-24. PMID:38397434. |
ms increased glial fibrillary acidic protein (gfap) and brain-derived neurotrophic factor expression in pfc and ionised calcium-binding adapter molecule-1 expression in male hippocampus. |
2024-02-24 |
2024-02-26 |
rat |
| Alicia C Wells, Shahrdad Lotfipou. Prenatal nicotine exposure during pregnancy results in adverse neurodevelopmental alterations and neurobehavioral deficits. Advances in drug and alcohol research. vol 3. 2024-02-23. PMID:38389806. |
due to the large percentage of women utilizing nicotine products during pregnancy in the united states and globally, this review seeks to centralize pre-clinical and clinical studies focused on the neurobehavioral and neurodevelopmental complications associated with prenatal nicotine exposure (pne) such as alterations to the hypothalamic-pituitary-adrenal (hpa) axis and brain regions such as the prefrontal cortex (pfc), ventral tegmental area (vta), nucleus accumbens (na), hippocampus, and caudate as well as changes to nachr and cholinergic receptor signaling, long-term drug seeking behavior following pne, and other related developmental disorders. |
2024-02-23 |
2024-02-25 |
Not clear |
| Gangjing Li, Li Hu, Xiangcheng Gu, Weijun Zhu, Xuechu Zhen, Xiaohui Su. Targeting Large-Conductance Calcium-Activated Potassium Channels to Ameliorate Lipopolysaccharide-Induced Depressive-Like Behavior in Mice. Neurochemical research. 2024-02-22. PMID:38383879. |
), a specific bk channel blocker, or bk shrna-aav effectively inhibited the activation of microglia, reduced the production of il-1β in the hippocampus and suppressed the expression and activity of ido in the hippocampus and prefrontal cortex, resulting in the amelioration of depressive-like behavior in mice. |
2024-02-22 |
2024-02-24 |
mouse |
| Shaohua You, Yishuang Wu, Yongxin Guo, Meng Wu, Mingzi Ran, Fuyang Cao, Xinyu Hao, Lujia Yang, Hong Zhang, Weidong Mi, Li Ton. Sevoflurane exerts antidepressant-like effects via the BDNF-TrkB pathway. Behavioural brain research. 2024-02-22. PMID:38387696. |
we then used western blotting to scrutinized the expression levels of proteins associated with the brain-derived neurotrophic factor (bdnf)-tryosine receptor kinase b (trkb) pathway in the hippocampus and prefrontal cortex. |
2024-02-22 |
2024-02-25 |
mouse |
| George Ntoulas, Charalampos Brakatselos, Gerasimos Nakas, Michail-Zois Asprogerakas, Foteini Delis, Leonidas J Leontiadis, George Trompoukis, Costas Papatheodoropoulos, Dimitrios Gkikas, Dimitrios Valakos, Giannis Vatsellas, Panagiotis K Politis, Alexia Polissidis, Katerina Antonio. Multi-level profiling of the Fmr1 KO rat unveils altered behavioral traits along with aberrant glutamatergic function. Translational psychiatry. vol 14. issue 1. 2024-02-20. PMID:38378836. |
we found that these rats exhibit hyperactivity and cognitive deficits, along with characteristic bidirectional glutamatergic and gabaergic alterations in the prefrontal cortex and the hippocampus. |
2024-02-20 |
2024-02-23 |
mouse |
| Gabriela Hossu, Luca Fantin, Céline Charroud, Jacques Felblinger, Muriel Jacquot, Hadrien Ceyt. Neural mechanisms of odour imagery induced by non-figurative visual cues. Neuropsychologia. 2024-02-19. PMID:38373518. |
our findings reveal that the use of non-figurative coloured arrangements during odour imagery solicits olfactory and non-olfactory brain regions (orbitofrontal cortex, insula, hippocampus, thalamus, dorsolateral prefrontal cortex and supplementary motor area), which are mainly involved in olfactory processing and multimodal integration. |
2024-02-19 |
2024-02-22 |
Not clear |
| Fernando Yáñez-Gómez, Laura Gálvez-Melero, Sandra Ledesma-Corvi, Cristian Bis-Humbert, Elena Hernández-Hernández, Glòria Salort, Rubén García-Cabrerizo, M Julia García-Fuste. Evaluating the daily modulation of FADD and related molecular markers in different brain regions in male rats. Journal of neuroscience research. vol 102. issue 2. 2024-02-16. PMID:38361411. |
therefore, we characterized the 24-h regulation of fadd (and linked molecular partners: p-erk/t-erk ratio, cdk-5, p35/p25, cell proliferation) in key brain regions for fadd regulation (prefrontal cortex, striatum, hippocampus). |
2024-02-16 |
2024-02-18 |
human |
| Fayezeh Hosseini, Fatemeh Khakpai, Soheila Fazli-Tabaei, Mohammad Nasehi, Mohammad-Reza Zarrindas. Interaction between citalopram and omega-3 fatty acids on anxiety and depression behaviors and maintaining the stability of brain pyramidal neurons in mice. Neuroscience letters. 2024-02-15. PMID:38360146. |
these results suggested an interaction between citalopram and omega-3 upon the induction of anxiolytic- and antidepressant-like effects as well as augmentation of the ratio of pyramidal live to dark neurons in the pfc and hippocampus of the ars and crs mice. |
2024-02-15 |
2024-02-18 |
mouse |
| Qianwen Zhang, Fujun Che. Impact of single-trial avoidance learning on subsequent sleep. The European journal of neuroscience. 2024-02-11. PMID:38342099. |
through cortical eeg recordings of prefrontal cortex and hippocampus during and after an inhibitory avoidance task, we analysed the dynamic changes in the amounts of sleep, spindle and ripple oscillations related to memory formation. |
2024-02-11 |
2024-02-14 |
Not clear |
| Christopher J E Denning, Lauren E Madory, Jessica N Herbert, Ryan A Cabrera, Karen K Szumlinsk. Neuropharmacological Evidence Implicating Drug-Induced Glutamate Receptor Dysfunction in Affective and Cognitive Sequelae of Subchronic Methamphetamine Self-Administration in Mice. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339206. |
relative to naïve controls, ma-experienced mice exhibited several changes in the expression of certain glutamate receptor-related proteins and their downstream effectors within the ventral and dorsal areas of the prefrontal cortex, the hippocampus, and the amygdala, many of which were sex-selective. |
2024-02-10 |
2024-02-12 |
mouse |
| b' David Olivares-Berjaga, Albert Mart\\xc3\\xadnez-Pinte\\xc3\\xb1o, Natalia Rodr\\xc3\\xadguez, Santiago Madero, Lluc\\xc3\\xada Prohens, Irene Mart\\xc3\\xadnez-Serrano, Sergi Mas, Constanza Mor\\xc3\\xa9n, Eduard Parellada, Patricia Gass\\xc3\\xb. Effects of the PAM of mGluR2, JNJ-46356479, on brain apoptotic protein levels in a mouse model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 131. 2024-02-10. PMID:38296154.' |
we analysed the levels of proapoptotic (caspase-3 and bax) and antiapoptotic (bcl-2) proteins by western blot in the prefrontal cortex and hippocampus of jnj-treated mice. |
2024-02-10 |
2024-02-14 |
mouse |
| Khadijeh Mirzaee Khoram-Abadi, Sara Haratizadeh, Mohsen Basiri, Mahdieh Parvan, Fahimeh Pourjafari, Iraj Aghaei, Sedigheh Amiresmaili, Masoumeh Nozar. Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus. Iranian journal of basic medical sciences. vol 27. issue 3. 2024-02-09. PMID:38333751. |
autistic-like behaviors are attenuated by agmatine consumption during pregnancy: assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and ca1 region of the hippocampus. |
2024-02-09 |
2024-02-11 |
rat |
| Khadijeh Mirzaee Khoram-Abadi, Sara Haratizadeh, Mohsen Basiri, Mahdieh Parvan, Fahimeh Pourjafari, Iraj Aghaei, Sedigheh Amiresmaili, Masoumeh Nozar. Autistic-like behaviors are attenuated by agmatine consumption during pregnancy: Assessment of oxidative stress profile and histopathological changes in the prefrontal cortex and CA1 region of the hippocampus. Iranian journal of basic medical sciences. vol 27. issue 3. 2024-02-09. PMID:38333751. |
due to the crucial role of polyamines during fetal growth and development, we aimed to determine the effect of prenatal administration of agmatine, an endogenous active metabolite of arginine, and a nutritional supplement, on autistic-like behaviors, oxidative-anti-oxidative profile, and histopathological changes of the prefrontal cortex (pfc) and ca1 area of the hippocampus in valproic acid (vpa) model of autism in male rats. |
2024-02-09 |
2024-02-11 |
rat |
| Aaron Y Lai, Dustin Loren V Almanza, Jessica A Ribeiro, Mary E Hill, Matthew Mandrozos, Margaret M Koletar, Bojana Stefanovic, JoAnne McLauri. Obesity Facilitates Sex-Specific Improvement In Cognition And Neuronal Function In A Rat Model Of Alzheimer's Disease. bioRxiv : the preprint server for biology. 2024-02-08. PMID:38328066. |
pathological analyses of prefrontal cortex and hippocampus showed that obesity in tgf344-ad rats produced varied effects, with increased density of myelin and oligodendrocytes, lowered density and activation of microglia that we propose contributes to the cognitive improvement. |
2024-02-08 |
2024-02-10 |
human |
| Hussain N Alhamami, Abdullah M Albogami, Mohammad M Algahtani, Mohammed Alqinyah, Wael A Alanazi, Fawaz Alasmari, Khalid Alhazzani, Ahmed Z Alanazi, Yasseen A Alassmrry, Abdullah S Alhame. The effect of inhibiting hindbrain A2 noradrenergic neurons by 6-Hydroxydopamine on lipopolysaccharide-treated male rats autistic animal model. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 32. issue 3. 2024-02-08. PMID:38328791. |
multiple studies have documented the presence of neuroinflammation and increased levels of inflammatory cytokines, specifically, il-6, tnf, and nf-κb, in various brain regions, including the prefrontal cortex (pfc) and hippocampus in individuals with asd. |
2024-02-08 |
2024-02-10 |
rat |