| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aurore Thomazeau, Olivier Lassalle, Olivier J Manzon. Glutamatergic synaptic deficits in the prefrontal cortex of the Ts65Dn mouse model for Down syndrome. Frontiers in neuroscience. vol 17. 2023-10-16. PMID:37841687. |
while there has been considerable research focused on the ts65dn mouse model of ds, particularly in the context of the hippocampus, the synaptic underpinnings of prefrontal cortex (pfc) dysfunction in ds, including deficits in working memory, remain largely uncharted territory. |
2023-10-16 |
2023-11-08 |
mouse |
| Mauritz Frederick Herselman, Larisa Bobrovskay. The Effects of Chronic Unpredictable Mild Stress and Semi-Pure Diets on the Brain, Gut and Adrenal Medulla in C57BL6 Mice. International journal of molecular sciences. vol 24. issue 19. 2023-10-14. PMID:37834073. |
cums induced anxiety-like behaviour, dysregulated the tryptophan and serotonin metabolic pathways in the hippocampus, prefrontal cortex, and colon, and altered the composition of the gut microbiota. |
2023-10-14 |
2023-10-15 |
mouse |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |
| Melek Hande Bulut Demir, Rahime Kaya, Ozgun Ozalay, Damla Isman Haznedaroglu, Yigit Erdogan, Omer Kitis, Tezan Bildik, Ali Saffet Gonul, Mehmet Cagdas Eke. The effects of sexual abuse on female adolescent brain structures. Scandinavian journal of child and adolescent psychiatry and psychology. vol 11. issue 1. 2023-10-11. PMID:37818143. |
we hypothesized that children with sa would have a thinner pfc with larger amygdala and hippocampus that lead to aberrations in threat detection, orientation and response circuit; that would be highly adaptive in a dangerous environment in the short term. |
2023-10-11 |
2023-10-15 |
Not clear |
| Helia Aghamiri, Majid Jafari-Sabet, Mahmood Hoorman. Ameliorative Effect of Cannabidiol on Topiramate-Induced Memory Loss: The Role of Hippocampal and Prefrontal Cortical NMDA Receptors and CREB/BDNF Signaling Pathways in Rats. Neurochemical research. 2023-10-09. PMID:37814133. |
western blot analysis was used to evaluate variations in brain-derived neurotrophic factor (bdnf) and phosphorylated cyclic amp response element-binding protein (pcreb)/creb ratio in the prefrontal cortex (pfc) and hippocampus (hpc). |
2023-10-09 |
2023-10-15 |
rat |
| William Almaguer-Melian, Daymara Mercerón-Martinez, Esteban Alberti-Amador, Laura Alacán-Ricardo, Javier Curi de Bardet, Norma Orama-Rojo, Arturo Ernesto Vergara-Piña, Idalia Herrera Estrada, Jorge A Bergad. Learning induces EPO/EPOr expression in memory relevant brain areas, whereas exogenously applied EPO promotes remote memory consolidation. Synapse (New York, N.Y.). 2023-10-05. PMID:37794768. |
data show that learning induces epo/epor expression increase linked to memory extent, exogenous epo prolongs memory up to 21 days; and prefrontal cortex bdnf expression at 24 h and in the hippocampus at 21 days, whereas arc expression increases at 21 days in the hippocampus and prefrontal cortex. |
2023-10-05 |
2023-10-07 |
Not clear |
| C Bañuelos, J R Kittleson, K H LaNasa, C S Galiano, S M Roth, E J Perez, J M Long, M T Roberts, S Fong, P R Rap. Cognitive Aging and the Primate Basal Forebrain Revisited: Disproportionate GABAergic Vulnerability Revealed. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-10-05. PMID:37798131. |
although a long history of research on neurocognitive aging has focused on the role of the cholinergic basal forebrain system, intermingled gabaergic cells are numerically as prominent and well-positioned to regulate the activity of their cortical projection targets, including the hippocampus and prefrontal cortex. |
2023-10-05 |
2023-10-07 |
monkey |
| Raoni Conceição Dos-Santos, Brook L W Sweeten, Claire E Stelly, Jeffrey G Taske. The Neuroendocrine Impact of Acute Stress on Synaptic Plasticity. Endocrinology. 2023-10-03. PMID:37788632. |
we describe the synaptic plasticity that occurs in four stress-associated brain structures, the hypothalamus, hippocampus, amygdala, and prefrontal cortex, in response to single or short-term stress exposure. |
2023-10-03 |
2023-10-07 |
Not clear |
| Susana Bulnes, Marina Picó-Gallardo, Harkaitz Bengoetxea, José Vicente Lafuent. Effects of curcumin nanodelivery on schizophrenia and glioblastoma. International review of neurobiology. vol 171. 2023-10-02. PMID:37783555. |
schizophrenia is a disabling psychiatric disorder related with an aberrant functional coupling between hippocampus and prefrontal cortex that might be crucial for cognitive dysfunction. |
2023-10-02 |
2023-10-07 |
Not clear |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
the present study aimed to evaluate the functional interaction between the dopaminergic and glutamatergic systems of the mediodorsal thalamus (md), the ventral hippocampus (vh), and the prefrontal cortex (pfc) in nicotine-induced anxiogenic-like behaviors. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
systemic administration of nicotine at a dose of 0.5 mg/kg induced an anxiogenic-like response associated with decreased bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
intra-md microinjection of apomorphine (0.1-0.3 μg/rat) induced an anxiogenic-like response, while apomorphine inhibited nicotine-induced anxiogenic-like behaviors associated with increased hippocampal and pfc bdnf expression levels. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
interestingly, the blockade of the vh or the pfc nmda receptors via the microinjection of d-ap5 (0.3-0.5 μg/rat) into the targeted sites reversed the inhibitory effect of apomorphine (0.5 μg/rat, intra-md) on the nicotine response and led to the decrease of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Seyedeh Leila Mousavi, Ameneh Rezayof, Sakineh Alijanpour, Ladan Delphi, Oveis Hosseinzadeh Sahaf. Activation of mediodorsal thalamic dopamine receptors inhibited nicotine-induced anxiety in rats: A possible role of corticolimbic NMDA neurotransmission and BDNF expression. Pharmacology, biochemistry, and behavior. 2023-10-01. PMID:37778541. |
these findings suggest that the functional interaction between the md dopaminergic d1/d2-like and the vh/pfc glutamatergic nmda receptors may be partially involved in the anxiogenic-like effects of nicotine, likely via the alteration of bdnf levels in the hippocampus and the pfc. |
2023-10-01 |
2023-10-07 |
rat |
| Giulia Galimberti, Giada Amodeo, Giulia Magni, Benedetta Riboldi, Gianfranco Balboni, Valentina Onnis, Stefania Ceruti, Paola Sacerdote, Silvia Franch. Prokineticin System Is a Pharmacological Target to Counteract Pain and Its Comorbid Mood Alterations in an Osteoarthritis Murine Model. Cells. vol 12. issue 18. 2023-09-28. PMID:37759478. |
in addition, pk upregulation and reactive astrogliosis in the hippocampus and microglia reactivity in the prefrontal cortex were detected. |
2023-09-28 |
2023-10-07 |
mouse |
| María Marcela Velásquez, María Claudia Lattig, Luis Carlos Chitiva, Geison M Costa, Jhon Jairo Sutachan, Sonia Luz Albarraci. Dendritogenic Potential of the Ethanol Extract from Molecules (Basel, Switzerland). vol 28. issue 18. 2023-09-28. PMID:37764442. |
dendritogenic potential of the ethanol extract from a reduced dendritic complexity, especially in regions such as the hippocampus and the prefrontal cortex, has been linked to the pathophysiology of some neuropsychiatric disorders, in which synaptic plasticity and functions such as emotional and cognitive processing are compromised. |
2023-09-28 |
2023-10-07 |
Not clear |
| V I Arkhipov, I Yu Chernomorets, N S Zhuikova, D A Fedorov, E V Pershin. The Role of NMDA Receptor Subunits in the Effect of Memantine on the Brain of Healthy Animals. Bulletin of experimental biology and medicine. 2023-09-28. PMID:37768458. |
the results showed that the glun2c subunit (grin2c) plays an important role in the effects of memantine; against the background of memantine treatment, the expression of this subunit markedly decreased in the prefrontal cortex, but not in the hippocampus, which significantly affected the excitation/inhibition balance in cortical structures. |
2023-09-28 |
2023-10-07 |
rat |
| Omar Gammoh, Esam Y Qnais, Rabaa Y Athamneh, Bilal Al-Jaidi, Deniz Al-Tawalbeh, Sara Altaber, Abdelrahim Alqudah, Alaa A A Aljabali, Murtaza M Tambuwal. Unraveling the Potential of Isorhamnetin as an Adjuvant in Depression Treatment with Escitalopram. Current issues in molecular biology. vol 45. issue 9. 2023-09-27. PMID:37754268. |
additionally, enzyme-linked immunosorbent assays were utilized to measure nrf2, bdnf, ho-1, no, and il-6 levels in the prefrontal cortex and hippocampus. |
2023-09-27 |
2023-10-07 |
mouse |
| Pedro A Feliciano-Ramos, Maria Galazo, Hector Penagos, Matthew Wilso. Hippocampal memory reactivation during sleep is correlated with specific cortical states of the retrosplenial and prefrontal cortices. Learning & memory (Cold Spring Harbor, N.Y.). vol 30. issue 9. 2023-09-27. PMID:37758288. |
interestingly, the most prevalent interaction with memory reactivation in the hippocampus occurred during sustained up states of the pfc and rtc, while hippocampal reactivation and cortical up-to-down state transition in the rtc showed the strongest coordination. |
2023-09-27 |
2023-10-07 |
Not clear |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
in addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-ht1a, 5-ht2a, and 5-ht3 in brain regions that regulate mood, emotions, and memory, such as the prefrontal cortex, hippocampus, and amygdala. |
2023-09-15 |
2023-10-07 |
rat |