| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Patterton, W P Hayes, Y B Sh. Transcriptional activation of the matrix metalloproteinase gene stromelysin-3 coincides with thyroid hormone-induced cell death during frog metamorphosis. Developmental biology. vol 167. issue 1. 1995-03-16. PMID:7851646. |
these findings implicate that st3 participates in the modification of the extracellular matrix during matamorphic apoptosis, but northern analyses using heterologous probes raise the possibility that additional matrix metalloproteinases may also be involved. |
1995-03-16 |
2023-08-12 |
Not clear |
| L M Desjardins, J P MacManu. An adherent cell model to study different stages of apoptosis. Experimental cell research. vol 216. issue 2. 1995-03-09. PMID:7843282. |
the main advantages of this adherent cell model are: (1) apoptosis occurs very slowly (minimum of 48 h) permitting the observation of progressive changes; (2) cells from four stages of apoptosis can be used to study the sequence of events of other biochemical and genetic factors involved in the process; and (3) extracellular matrix proteins are present in this model so their participation in apoptosis, if any, can be determined. |
1995-03-09 |
2023-08-12 |
Not clear |
| N Boudreau, C J Sympson, Z Werb, M J Bissel. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (New York, N.Y.). vol 267. issue 5199. 1995-03-06. PMID:7531366. |
suppression of ice and apoptosis in mammary epithelial cells by extracellular matrix. |
1995-03-06 |
2023-08-12 |
Not clear |
| N Boudreau, C J Sympson, Z Werb, M J Bissel. Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix. Science (New York, N.Y.). vol 267. issue 5199. 1995-03-06. PMID:7531366. |
basement membrane extracellular matrix (ecm), but not fibronectin or collagen, was shown to suppress apoptosis of mammary epithelial cells in tissue culture and in vivo. |
1995-03-06 |
2023-08-12 |
Not clear |
| C Demarcq, R T Bunch, D Creswell, A Eastma. The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 5. issue 9. 1995-02-14. PMID:7819136. |
these cells subsequently lost contact with the extracellular matrix, and only then digested their dna in a manner characteristic of apoptosis. |
1995-02-14 |
2023-08-12 |
Not clear |
| C Demarcq, R T Bunch, D Creswell, A Eastma. The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 5. issue 9. 1995-02-14. PMID:7819136. |
it is hypothesized that the dna digestion results from loss of signal transduction originating from the extracellular matrix but that earlier events leading to loss of cell adhesion are critical for the induction of apoptosis. |
1995-02-14 |
2023-08-12 |
Not clear |
| B K Joseph, G C Gobé, N W Savage, W G Youn. Expression and localization of sulphated glycoprotein-2 mRNA in the rat incisor tooth ameloblasts: relationships with apoptosis. International journal of experimental pathology. vol 75. issue 5. 1995-01-23. PMID:7999633. |
an additional 25% of ameloblasts undergo apoptosis when maturation of enamel matrix takes place with removal of water and protein from the increasingly mineralized matrix. |
1995-01-23 |
2023-08-12 |
rat |
| L Kokilev. Multi-step chromatin degradation in apoptosis. DNA breakdown in apoptosis. International archives of allergy and immunology. vol 105. issue 4. 1995-01-03. PMID:7981601. |
detachment of chromatin from the nuclear matrix attachment regions may be one of the possible mechanisms of switching off the genome function and triggering the multi-step process of endogenous chromatin degradation, thus leading to cell death of terminal differentiation or stress-induced apoptosis. |
1995-01-03 |
2023-08-12 |
Not clear |
| F Re, A Zanetti, M Sironi, N Polentarutti, L Lanfrancone, E Dejana, F Colott. Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells. The Journal of cell biology. vol 127. issue 2. 1994-11-07. PMID:7523422. |
to obtain information as to the mechanism involved in the apoptosis of suspended ec, we investigated whether adhesion to matrix proteins or integrin occupancy in ec retaining a round shape may affect ec suicide. |
1994-11-07 |
2023-08-12 |
human |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
variant melanoma cells, lacking the alpha v subunit, progressed rapidly to apoptosis within this matrix, whereas transfection of these cells with an alpha v cdna restored alpha v beta 3 expression and prevented apoptosis. |
1994-10-14 |
2023-08-12 |
human |
| A M Montgomery, R A Reisfeld, D A Cheres. Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 19. 1994-10-14. PMID:7522323. |
apoptosis of alpha v(-) cells within this matrix could be overcome by the addition of insulin or serum. |
1994-10-14 |
2023-08-12 |
human |
| F A Oberhammer, K Hochegger, G Fröschl, R Tiefenbacher, M Pavelk. Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase. The Journal of cell biology. vol 126. issue 4. 1994-09-06. PMID:8051209. |
chromatin condensation during apoptosis appears to be due to a rapid proteolysis of nuclear matrix proteins which does not involve the p34cdc2 kinase. |
1994-09-06 |
2023-08-12 |
Not clear |
| Y Onishi, Y Azuma, H Kizak. bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis. Biochemistry and molecular biology international. vol 32. issue 1. 1994-07-25. PMID:8012276. |
the alteration of dna helicity induced by a subtle inhibition of topoisomerase ii activity may have an important role in the induction of apoptosis in thymocytes, since topoisomerase ii is a major component of the nuclear matrix that can regulate gene expression. |
1994-07-25 |
2023-08-12 |
mouse |
| S M Frisch, H Franci. Disruption of epithelial cell-matrix interactions induces apoptosis. The Journal of cell biology. vol 124. issue 4. 1994-03-24. PMID:8106557. |
the present report demonstrates that apoptosis was induced by disruption of the interactions between normal epithelial cells and extracellular matrix. |
1994-03-24 |
2023-08-12 |
Not clear |
| T Miller, L A Beausang, M Meneghini, G Lidgar. Death-induced changes to the nuclear matrix: the use of anti-nuclear matrix antibodies to study agents of apoptosis. BioTechniques. vol 15. issue 6. 1994-03-01. PMID:8292336. |
death-induced changes to the nuclear matrix: the use of anti-nuclear matrix antibodies to study agents of apoptosis. |
1994-03-01 |
2023-08-12 |
Not clear |
| A J Moule, W G Young, K F Adkin. Early cellular events in an actinomycin D-created dentin niche in the rat incisor. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. vol 22. issue 4. 1993-07-23. PMID:8315595. |
these early stages were dominated by apoptosis and heterophagy, and after 80 h by disordered dentin matrix formation. |
1993-07-23 |
2023-08-12 |
rat |
| O Lefebvre, C Wolf, J M Limacher, P Hutin, C Wendling, M LeMeur, P Basset, M C Ri. The breast cancer-associated stromelysin-3 gene is expressed during mouse mammary gland apoptosis. The Journal of cell biology. vol 119. issue 4. 1992-12-04. PMID:1429845. |
since the st3 gene is also specifically expressed in fibroblastic cells surrounding invasive neoplastic cells of breast carcinomas, we suggest that st3 is implicated in extracellular matrix remodeling processes common to mammary apoptosis and breast cancer progression. |
1992-12-04 |
2023-08-11 |
mouse |
| D J Tobin, D A Fenton, M D Kendal. Cell degeneration in alopecia areata. An ultrastructural study. The American Journal of dermatopathology. vol 13. issue 3. 1991-09-12. PMID:1867355. |
keratinocytic degeneration may affect layers of matrix cells in alopecia areata, unlike the apoptosis of scattered outer root sheath cells in normal catagen. |
1991-09-12 |
2023-08-11 |
Not clear |
| M T Goldberg, L E Tackaberry, M H Hardy, J H Noseworth. Nuclear aberrations in hair follicle cells of patients receiving cyclophosphamide. A possible in vivo assay for human exposure to genotoxic agents. Archives of toxicology. vol 64. issue 2. 1990-07-09. PMID:2190540. |
the percent of cells with nuclear aberrations (indicating apoptosis, a special form of cell death) and the percent of mitotic cells, in the hair matrix, were calculated for each patient before treatment and at several time points following cyclophosphamide or placebo treatment. |
1990-07-09 |
2023-08-11 |
human |