| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Orosz, J P Bennet. Baseline and apomorphine-induced extracellular levels of nigral substance P are increased in an animal model of Parkinson's disease. European journal of pharmacology. vol 182. issue 3. 1990-12-12. PMID:1699767. |
parkinson's disease arises from extensive premature loss of dopamine (da)-utilizing midbrain neurons whose axons form the nigrostriatal pathway and densely innervate the striatum (caudate-putamen). |
1990-12-12 |
2023-08-11 |
rat |
| N Lindefors, U Ungersted. Bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons. Neuroscience letters. vol 115. issue 2-3. 1990-12-12. PMID:1978265. |
bilateral regulation of glutamate tissue and extracellular levels in caudate-putamen by midbrain dopamine neurons. |
1990-12-12 |
2023-08-11 |
rat |
| B K Nelson, W S Brightwell, E F Krie. Developmental toxicology of industrial alcohols: a summary of 13 alcohols administered by inhalation to rats. Toxicology and industrial health. vol 6. issue 3-4. 1990-12-11. PMID:2237924. |
additionally, brains were removed from 10 offspring per group at 21 days of age, and were dissected into cerebrum, cerebellum, brainstem, and midbrain; these samples were assayed for steady-state levels of protein and the neurotransmitters acetylcholine, dopamine, norepinephrine, 5-hydroxytryptamine (serotonin), substance p, b-endorphin, and met-enkephalin. |
1990-12-11 |
2023-08-11 |
rat |
| M Schalling, K Friberg, K Seroogy, P Riederer, E Bird, S N Schiffmann, P Mailleux, J J Vanderhaeghen, S Kuga, M Goldstei. Analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia. Proceedings of the National Academy of Sciences of the United States of America. vol 87. issue 21. 1990-12-07. PMID:1978324. |
analysis of expression of cholecystokinin in dopamine cells in the ventral mesencephalon of several species and in humans with schizophrenia. |
1990-12-07 |
2023-08-11 |
human |
| M D Kelland, A S Freeman, P A LeWitt, L A Chiod. Effects of (+)-4-propyl-9-hydroxynaphthoxazine on midbrain dopamine neurons: an electrophysiological study. The Journal of pharmacology and experimental therapeutics. vol 255. issue 1. 1990-11-21. PMID:1976800. |
effects of (+)-4-propyl-9-hydroxynaphthoxazine on midbrain dopamine neurons: an electrophysiological study. |
1990-11-21 |
2023-08-11 |
rat |
| A A Grac. Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain research. vol 524. issue 1. 1990-10-26. PMID:2400930. |
evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. |
1990-10-26 |
2023-08-11 |
rat |
| A A Grac. Evidence for the functional compartmentalization of spike generating regions of rat midbrain dopamine neurons recorded in vitro. Brain research. vol 524. issue 1. 1990-10-26. PMID:2400930. |
the regulation of spike generation in rat midbrain dopamine (da) neurons was investigated using in vitro intracellular recordings. |
1990-10-26 |
2023-08-11 |
rat |
| F Kawat. [Studies on monoamine metabolism in the rat brain with overdosage of manganese]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. vol 44. issue 2. 1990-10-24. PMID:2402098. |
1) in the mn-loaded rats, the concentration of dopamine (da) was significantly decreased in the nucleus caudatus-putamen (c/p)(p less than 0.05), the thalamus (p less than 0.05) and in the mesencephalon (me) (p less than 0.001), while that of homovanillic acid decreased in the c/p (p less than 0.05). |
1990-10-24 |
2023-08-11 |
rat |
| N Lindefors, S Brené, M Herrera-Marschitz, H Persso. Neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons. Experimental brain research. vol 80. issue 3. 1990-09-24. PMID:2387350. |
neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons. |
1990-09-24 |
2023-08-11 |
rat |
| N Lindefors, S Brené, M Herrera-Marschitz, H Persso. Neuropeptide gene expression in brain is differentially regulated by midbrain dopamine neurons. Experimental brain research. vol 80. issue 3. 1990-09-24. PMID:2387350. |
in situ hybridization was used to study the expression of prepro-neuropeptide y (npy), preprosomatostatin (som), preprotachykinin (ppt) and preprocholecystokinin (cck) mrna in caudate-putamen and frontoparietal cortex of rat brain with unilateral lesion of midbrain dopamine neurons. |
1990-09-24 |
2023-08-11 |
rat |
| E D French, S Levenson, A Cec. Characterization of the actions of phencyclidine on midbrain dopamine neurons. NIDA research monograph. vol 95. 1990-09-20. PMID:2561830. |
characterization of the actions of phencyclidine on midbrain dopamine neurons. |
1990-09-20 |
2023-08-11 |
Not clear |
| P Seeman, H B Nizni. Dopamine receptors and transporters in Parkinson's disease and schizophrenia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 4. issue 10. 1990-08-30. PMID:2197154. |
the loss of midbrain dopamine in parkinson's disease is accompanied by a matching loss in the dopamine transporter and a rise in the d1 and d2 receptor densities. |
1990-08-30 |
2023-08-11 |
Not clear |
| A D Smith, J P Bola. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones. Trends in neurosciences. vol 13. issue 7. 1990-08-23. PMID:1695400. |
the study of synaptic connections in the electron microscope has established an 'elementary' circuit for the neostriatum which consists of a pathway from cortical areas (neocortex, hippocampus, amygdala) to medium spiny neurones of the striatum that also receive converging synaptic input from midbrain dopamine neurones. |
1990-08-23 |
2023-08-11 |
Not clear |
| A D Smith, J P Bola. The neural network of the basal ganglia as revealed by the study of synaptic connections of identified neurones. Trends in neurosciences. vol 13. issue 7. 1990-08-23. PMID:1695400. |
it is proposed that certain parts of the striatum can themselves control the activity of midbrain dopamine neurones and so one part of the striatum can 'gate' the flow of information through another part. |
1990-08-23 |
2023-08-11 |
Not clear |
| K Haba, N Ogawa, A Mor. The effects of sho-saiko-to-go-keishi-ka-shakuyaku-to (TJ-960) on ischemia-induced changes of brain acetylcholine and monoamine levels in gerbils. Neurochemical research. vol 15. issue 5. 1990-08-23. PMID:2370941. |
in ischemic gerbil brains, the dopamine (da) levels decreased and its metabolites increased in the striatum, but da and its metabolites in the thalamus + midbrain region increased. |
1990-08-23 |
2023-08-11 |
Not clear |
| V V Bul'on, L K Khnychenk. [A pharmacological analysis of the central monoaminergic mechanisms of the development of neurogenic stomach damage]. Farmakologiia i toksikologiia. vol 53. issue 2. 1990-08-21. PMID:1973391. |
it was found that 3 hours after electrostimulation of the immobilized rats there was observed in addition to destructive lesions in the gastric mucosa a significant decrease of noradrenaline, dopamine, dopa, homovanillic acid and creatine phosphate levels in the brain tissue involving the hypothalamus and the midbrain surrounding it. |
1990-08-21 |
2023-08-11 |
rat |
| S Y Tam, J D Elsworth, C W Bradberry, R H Rot. Mesocortical dopamine neurons: high basal firing frequency predicts tyrosine dependence of dopamine synthesis. Journal of neural transmission. General section. vol 81. issue 2. 1990-08-13. PMID:2363911. |
mesocortical dopamine (da) neurons projecting to the prefrontal and cingulate cortices possess a faster basal firing rate and exhibit more bursting than other midbrain da neurons. |
1990-08-13 |
2023-08-11 |
Not clear |
| R Castro, B Brito, V Notari. Prenatal haloperidol alters the expression of DNA polymerases in brain regions of neonate rats. Cellular and molecular neurobiology. vol 10. issue 2. 1990-08-13. PMID:2364411. |
by northern blot analysis, we have studied the steady-state mrna levels for genes involved in dna metabolism, in neonate rat mesencephalon and forebrain, after chronic prenatal blockade of dopamine receptors with haloperidol. |
1990-08-13 |
2023-08-11 |
rat |
| T Kiriu, K Ameno, C Fuke, S Ameno, I Ijir. [The distribution of toluene in the brain and its effects on the brain catecholamines in acute toluene poisoning]. Nihon hoigaku zasshi = The Japanese journal of legal medicine. vol 44. issue 1. 1990-08-13. PMID:2366393. |
the inhalation of toluene (1,500 ppm and 10,000 ppm) caused decreases in the noradrenaline (na) levels in the dorsal part of rat pons, rich in locus coeruleus, and in the dopamine (da) levels in the hypothalamus and ventral part of the rat midbrain, rich in substantia nigra. |
1990-08-13 |
2023-08-11 |
rat |
| F G Williams, M P Murtaugh, A J Beit. The effect of acute haloperidol treatment on brain proneurotensin mRNA: in situ hybridization analyses using a novel fluorescence detection procedure. Brain research. Molecular brain research. vol 7. issue 4. 1990-07-31. PMID:2163009. |
these studies describe the normal anatomical distribution of neurons containing the mrna coding for neurotensin (proneurotensin/neuromedin n) in the rat forebrain and midbrain and examine how that distribution is altered by acute administration of the dopamine antagonist haloperidol. |
1990-07-31 |
2023-08-11 |
rat |