| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B A Gladue, R R Humphrys, J F Debold, L G Clemen. Ontogeny of biogenic amine systems and modification of indole levels upon adult sexual behavior in the rat. Pharmacology, biochemistry, and behavior. vol 7. issue 3. 1978-01-27. PMID:928481. |
in addition, flurometric analysis of norepinephrine, dopamine and serotonin from hypothalamus, mesencephalon and cortex was performed on male and female rats on day 8, 10, 12 and 14 postnatally to examine the development of various transmitter systems during the early postnatal period. |
1978-01-27 |
2023-08-11 |
rat |
| R B Rastogi, R L Singha. Lithium suppresses elevated behavioural activity and brain catecholamines in developing hyperthyroid rats. Canadian journal of physiology and pharmacology. vol 55. issue 3. 1977-09-29. PMID:18270. |
whereas administration of lithium carbonate (60 mg/kg ip) to normal rats for 6 days produced no effect on spontaneous locomotor activity and increased the synthesis and possibly release of this monoamine in several brain regions, this antimanic drug antagonized the l-triiodothyronine-stimulated increases in mobility as well as norepinephrine and dopamine metabolism of hypothalamus, midbrain, striatum, and cerebral cortex. |
1977-09-29 |
2023-08-11 |
rat |
| J Offermeier, B Potgieter, H G Du Preez, P J Meirin. Studies of the pharmacology of a new antidepressant, S1694. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde. vol 51. issue 3. 1977-03-31. PMID:13502. |
s1694 inhibits active dopamine (da) uptake into rat striatal synaptosomes, but not noradrenaline (na) uptake into rat hypothalamic synaptosomes, or serotonin (5-ht) uptake into rat midbrain synaptosomes, in the concentrations used. |
1977-03-31 |
2023-08-11 |
mouse |
| J Moniuszko-Jakoniuk, K Wiśniewsk. Studies on the central activity of kinins. Polish journal of pharmacology and pharmacy. vol 28. issue 6. 1977-03-21. PMID:1012986. |
the influence of bradykinin and kallikrein on the levels of noradrenaline (na), dopamine (da) and serotonin (5-ht) as well as the influence of bradykinin on the levels of normetanephrine, homovanillic (hva) and 5-hydroxyindoleacetic (5-hiaa) acids were investigated in different parts of the brain (cerebellum, corpus striatum, cortex, hippocampus, hypothalamus, medulla oblongata and midbrain). |
1977-03-21 |
2023-08-11 |
Not clear |
| J Moniuszko-Jakoniuk, M Kościela. Influence of kinins on amphetamine activity. Polish journal of pharmacology and pharmacy. vol 28. issue 6. 1977-03-21. PMID:1012987. |
a treatment with bradykinin and the low dose of amphetamine reduced the noradrenaline and enhanced the serotonin level in the striatum, and lowered the dopamine content in the cortex, while a combined treatment with the high dose of amphetamine elevated the dopamine level in the striatum and hypothalamus and depressed the serotonin level in the midbrain. |
1977-03-21 |
2023-08-11 |
Not clear |
| J Moniuszko-Jakoniuk, K Wisniewski, M Kosciela. Investigations of the mechanism of central action of kinins. Psychopharmacology. vol 50. issue 2. 1977-02-24. PMID:12529. |
the effects of kinins on the level of norepinephrine, dopamine, and serotonin and on their metabolites, i.e., normetanephrine, homovanillic acid, and 5-hydroxyindoloacetic acid in the brain tissue divided into cerebellum, corpus striatum, cortex, hippocampus, hypothalamus, medulla oblongata, and midbrain were investigated. |
1977-02-24 |
2023-08-11 |
Not clear |
| J Moniuszko-Jakoniuk, K Wisniewski, M Kosciela. Investigations of the mechanism of central action of kinins. Psychopharmacology. vol 50. issue 2. 1977-02-24. PMID:12529. |
it also decreased the level of dopamine in corpus striatum but increased the level of serotonin in corpus striatum and midbrain. |
1977-02-24 |
2023-08-11 |
Not clear |
| M Simon, R George, J Garci. Acute morphine effects on regional brain amines, growth hormone and corticosterone. European journal of pharmacology. vol 34. issue 1. 1977-02-24. PMID:1234764. |
at 4:00 pm, the rats were decapitated and norepinephrine, dopamine and serotonin levels were measured in seven brain regions (cortex, striatum septum, amygdala, hypothalamus, midbrain and pons). |
1977-02-24 |
2023-08-11 |
rat |
| S N Glisson, A A el-Etr, B C Bloo. The effect of ketamine upon norepinephrine and dopamine levels in rabbit brain parts. Naunyn-Schmiedeberg's archives of pharmacology. vol 295. issue 2. 1977-01-25. PMID:995210. |
significantly increased dopamine levels in the thalamus and hypothalamus brain areas, but not in the midbrain or caudate nucleus. |
1977-01-25 |
2023-08-11 |
rabbit |
| R B Rastogi, R L Singha. Influence of neonatal and adult hyperthyroidism on behavior and biosynthetic capacity for norepinephrine, dopamine and 5-hydroxytryptamine in rat brain. The Journal of pharmacology and experimental therapeutics. vol 198. issue 3. 1976-12-23. PMID:978462. |
the concentration of dopamine remained unchanged in all regions of the brain except in midbrain where it rose by 19%. |
1976-12-23 |
2023-08-11 |
rat |
| S Shimada, M Ishikawa, C Tanak. Histochemical mapping of dopamine neurons and fiber pathways in dog mesencephalon. The Journal of comparative neurology. vol 168. issue 4. 1976-09-25. PMID:939821. |
histochemical mapping of dopamine neurons and fiber pathways in dog mesencephalon. |
1976-09-25 |
2023-08-11 |
dog |
| S Shimada, M Ishikawa, C Tanak. Histochemical mapping of dopamine neurons and fiber pathways in dog mesencephalon. The Journal of comparative neurology. vol 168. issue 4. 1976-09-25. PMID:939821. |
a topographic mapping of dopamine (da)-containing neurons and fibers was done mainly in the mesencephalon of the dog using the fluorescent histochemical technique of falck and hillarp. |
1976-09-25 |
2023-08-11 |
dog |
| J N Hingtgen, J E Smith, P A Shea, M H Aprison, T M Gaf. Cholinergic changes during conditioned suppression in rats. Science (New York, N.Y.). vol 193. issue 4250. 1976-08-23. PMID:7016. |
levels of acetylcholine were significantly elevated in the telencephalon and diencephalon + mesencephalon of rats killed by near-freezing during conditioned suppression of food-reinforced lever pressing, whereas levels of serotonin, dopamine, and norepinephrine were not altered. |
1976-08-23 |
2023-08-11 |
rat |
| P J Langlais, P C Huang, S Gaba. Regional neurochemical studies on the effect of beta, beta'-iminodipropionitrile (IDPN) in the rat. Journal of neuroscience research. vol 1. issue 5-6. 1976-08-02. PMID:1241588. |
the levels of the biogenic amines, norepinephrine (ne), dopamine (da), serotonin (5-ht) and its metabolite 5-hydroxyindoleacetic acid (5-hiaa), were measured in the striatum, midbrain, medulla, cortex, and cerebellum on the day the syndrome appeared (day 7) and one week later (day 14). |
1976-08-02 |
2023-08-11 |
rat |
| J L Perhach, A W Gomol. Antihypertensive activity of 2-amino-4-(3,4-dichlorophenyl)-2-imidazoline (MJ 10459-2) and catecholamine reduction. Research communications in chemical pathology and pharmacology. vol 12. issue 1. 1976-01-26. PMID:1188182. |
no reductions in the content of norepinephrine, dopamine, serotonin or 5-hydroxyindoleacetic acid were noted in the cerebrum, cerebellum, midbrain or medulla/pons area of brain after 1 and 4 mg/kg of mj 10459-2. |
1976-01-26 |
2023-08-11 |
rat |
| B Costall, R J Naylo. Neuropharmacological studies on D145 (1,3-dimethyl-5-aminoadamantan). Psychopharmacologia. vol 43. issue 1. 1975-12-04. PMID:1099605. |
in addition, the possible importance of 5-hydroxytryptamine to the dopamine effects was investigated using electrolytic lesions of the midbrain raphé nuclei. |
1975-12-04 |
2023-08-11 |
rat |
| J L Burton, S K Goolamali, S Shuste. An abnormality in sebaceous function in phenylketonuria. British medical journal. vol 1. issue 5948. 1975-06-19. PMID:123473. |
this may be related to a depletion of midbrain dopamine and release of the sebotrophic hormone. |
1975-06-19 |
2023-08-11 |
Not clear |
| R Samanin, S Bernascon. Effects of intraventriculary injected 6-OH dopamine or midbrain raphe lesion on morphine analgesia in rats. Psychopharmacologia. vol 25. issue 2. 1972-09-22. PMID:4538029. |
effects of intraventriculary injected 6-oh dopamine or midbrain raphe lesion on morphine analgesia in rats. |
1972-09-22 |
2023-08-11 |
rat |
| H C Guldberg, C M Yate. Effects of chlorpromazine on the metabolism of catecholamines in dog brain. British journal of pharmacology. vol 36. issue 3. 1969-08-08. PMID:5789808. |
experiments had indicated as producing maximal and minimal effects on dopamine metabolism in brain tissue, were studied by estimating the concentrations of adrenaline, noradrenaline, dopamine, metanephrine, methoxydopamine, homovanillic acid, 3,4-dihydroxyphenylacetic acid and 5-hydroxyindolylacetic acid in the hypothalamus, midbrain, thalamus, hindbrain, cortex, globus pallidus and caudate nucleus of control dogs and of dogs treated with cpz intravenously 2 hr before killing. |
1969-08-08 |
2023-08-12 |
dog |
| H C Guldberg, C M Yate. Effects of chlorpromazine on the metabolism of catecholamines in dog brain. British journal of pharmacology. vol 36. issue 3. 1969-08-08. PMID:5789808. |
dopamine: cpz 5 mg/kg produced no change in the concentration in the caudate nucleus, globus pallidus and midbrain and increased the concentration in the thalamus; cpz 15 mg/kg appeared to cause a reduction in the concentration of this amine in the caudate nucleus and globus pallidus. |
1969-08-08 |
2023-08-12 |
dog |