| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K W Delan. [Olfactory sensitivity in adenoid hyperplasia]. Laryngo- rhino- otologie. vol 71. issue 6. 1992-09-03. PMID:1637448. |
the results suggest that preoperative olfactory detection thresholds in subjects with severe nasal obstruction attributable to adenoid hypertrophy are higher than in those with less severe nasal obstruction. |
1992-09-03 |
2023-08-11 |
human |
| K W Delan. [Olfactory sensitivity in adenoid hyperplasia]. Laryngo- rhino- otologie. vol 71. issue 6. 1992-09-03. PMID:1637448. |
the olfactory detection thresholds improved after adenectomy in cases with high preoperative nasal obstruction indices. |
1992-09-03 |
2023-08-11 |
human |
| B A Trela, S R Frame, M S Bogdanff. A microscopic and ultrastructural evaluation of dibasic esters (DBE) toxicity in rat nasal explants. Experimental and molecular pathology. vol 56. issue 3. 1992-09-01. PMID:1639180. |
dibasic esters (dbe) solvent has been demonstrated to induce a mild degeneration of the olfactory, but not the respiratory epithelium of the rat nasal cavity following a 90-day inhalation exposure. |
1992-09-01 |
2023-08-11 |
rat |
| G R Lundqvist, M Yamagiwa, O F Pedersen, G D Nielse. Inhalation of diethylamine--acute nasal effects and subjective response. American Industrial Hygiene Association journal. vol 53. issue 3. 1992-08-28. PMID:1642170. |
a moderate to strong olfactory response and distinct nasal and eye irritation were observed. |
1992-08-28 |
2023-08-11 |
human |
| S I Paik, M N Lehman, A M Seiden, H J Duncan, D V Smit. Human olfactory biopsy. The influence of age and receptor distribution. Archives of otolaryngology--head & neck surgery. vol 118. issue 7. 1992-08-19. PMID:1627295. |
thirty-six mucosal specimens were obtained with a biopsy instrument from the upper nasal septum of 12 human autopsy cases before the en bloc removal of the entire olfactory area. |
1992-08-19 |
2023-08-11 |
human |
| S I Paik, M N Lehman, A M Seiden, H J Duncan, D V Smit. Human olfactory biopsy. The influence of age and receptor distribution. Archives of otolaryngology--head & neck surgery. vol 118. issue 7. 1992-08-19. PMID:1627295. |
multiple patches of respiratory epithelium were observed over the upper portion of the nasal septum and superior turbinates, ie, the presumptive olfactory area. |
1992-08-19 |
2023-08-11 |
human |
| S Biffo, E Martí, A Fasol. Carnosine, nerve growth factor receptor and tyrosine hydroxylase expression during the ontogeny of the rat olfactory system. Journal of chemical neuroanatomy. vol 5. issue 1. 1992-07-23. PMID:1376608. |
all these molecules were expressed in the olfactory bulb but with different developmental patterns and cellular localization: carnosine immunoreactivity is seen from embryonic day 17 in primary olfactory neurons scattered in the nasal cavity and in fibres projecting from them to the olfactory bulb. |
1992-07-23 |
2023-08-11 |
rat |
| H C Scott, W K Paull, P K Rudee. Effects of in utero ethanol exposure on the development of LHRH neurons in the mouse. Brain research. Developmental brain research. vol 66. issue 1. 1992-07-10. PMID:1600625. |
however, the total number of irlhrh neurons on g18 was significantly less (p less than 0.03) in 4 neuroanatomical regions in fetal ethanol-exposed mice compared to those in control mice; the nasal septum, the traverse area superior to the cribriform plate and ventromedial to the olfactory bulbs, the arch area which included the olfactory tubercle, medial septal nuclei and anterior hypothalamus in g18 fetuses, and preoptic area of the brain. |
1992-07-10 |
2023-08-11 |
mouse |
| M A Hofer, H N Shai. Trigeminal and olfactory pathways mediating isolation distress and companion comfort responses in rat pups. Behavioral neuroscience. vol 105. issue 5. 1992-06-30. PMID:1815619. |
these responses were studied in pups with surgical lesions of trigeminal snout afferents and after olfactory denervation by nasal znso4 perfusion. |
1992-06-30 |
2023-08-11 |
rat |
| M A Sarka. Drug metabolism in the nasal mucosa. Pharmaceutical research. vol 9. issue 1. 1992-06-24. PMID:1589391. |
the cytochrome p-450 activity in the olfactory region of the nasal epithelium is higher even than in the liver, mainly because of a three- to fourfold higher nadph-cytochrome p-450 reductase content. |
1992-06-24 |
2023-08-11 |
Not clear |
| K T Morga. Approaches to the identification and recording of nasal lesions in toxicology studies. Toxicologic pathology. vol 19. issue 4 Pt 1. 1992-06-17. PMID:1813980. |
the following points are considered to be particularly important: 1) alert animal care staff to clinical changes that may indicate nasal lesions; 2) screen animals for nasal disease, such as nasal nematodes in non-human primates; 3) record gross lesions during trimming of decalcified nasal tissues; 4) save spare tissue in fixative; 5) remember that the normal bilateral symmetry of the nose can be a valuable diagnostic aid; 6) avoid excessive lumping or splitting of diagnoses; 7) develop a logical order for recording of lesions (the approach preferred by the author is degenerative, inflammatory, regenerative, proliferative, for each of the epithelial types in a logical anatomical order, such as squamous, transitional, respiratory, and olfactory); 8) accurately determine the site of toxic responses; 9) keep a notebook of interesting or important observations and ideas if you are using a computerized data acquisition system; 10) consider the role of factors that may account for lesion distribution (regional dose and tissue susceptibility) during interpretation of tissue responses; and 11) during preparation of the descriptive narrative, clearly define what occurred, where and when it occurred, and consider the use of simple anatomical diagrams as an adjunct to the text. |
1992-06-17 |
2023-08-11 |
human |
| H R Brown, T M Monticello, R R Maronpot, H W Randall, J R Hotchkiss, K T Morga. Proliferative and neoplastic lesions in the rodent nasal cavity. Toxicologic pathology. vol 19. issue 4 Pt 1. 1992-06-17. PMID:1813982. |
our general conclusions in this paper are that: 1) spontaneous nasal tumors in rodents are very rare; 2) spontaneous nasal tumors in rats are most often squamous cell tumors, whereas hemangiomas or respiratory adenomas predominate in mice and squamous cell tumors are rare; 3) rats are usually more susceptible to the induction of epithelial tumors of the nasal cavity than mice; 4) chemically-induced hemangiomas and hemangiosarcomas of the nasal cavity have only been reported in mice; 5) tumors of the olfactory epithelium are almost uniformly malignant and invasive, while nonsquamous tumors of the respiratory epithelium are typically less invasive; 6) chemically-induced tumors of the olfactory region, either mesenchymal or epithelial, do not always require an inhalation route of exposure but may occur by systemic targeting of this region; and 7) chemicals inducing tumors in the olfactory region often produce a variety of tumor morphologies in this location as well as squamous and polypoid tumors of the transitional region. |
1992-06-17 |
2023-08-11 |
mouse |
| S K Pixle. Purified cultures of keratin-positive olfactory epithelial cells: identification of a subset as neuronal supporting (sustentacular) cells. Journal of neuroscience research. vol 31. issue 4. 1992-06-05. PMID:1374479. |
the mammalian olfactory neuroepithelium, lining part of the nasal cavity, retains into adulthood progenitor cells for the olfactory receptor neurons and other cell types in the epithelium. |
1992-06-05 |
2023-08-11 |
rat |
| S K Pixle. Purified cultures of keratin-positive olfactory epithelial cells: identification of a subset as neuronal supporting (sustentacular) cells. Journal of neuroscience research. vol 31. issue 4. 1992-06-05. PMID:1374479. |
the conditions which supported growth of keratin-positive nasal cells for greater than one month, and allowed partial purification, suggested similarities between olfactory and skin keratinocytes. |
1992-06-05 |
2023-08-11 |
rat |
| V A Ahern, M G Poulse. Olfactory neuroblastoma--management of a rare tumour at the Queensland Radium Institute and literature review. Australasian radiology. vol 35. issue 4. 1992-06-05. PMID:1812831. |
olfactory neuroblastoma (esthesioneuroblastoma) is an extremely rare tumour arising from the olfactory epithelium of the nasal cavity close to the cribriform plate. |
1992-06-05 |
2023-08-11 |
Not clear |
| J L Lewis, C E Rhoades, D E Bice, J R Harkema, J A Hotchkiss, D M Sylvester, A R Dah. Interspecies comparison of cellular localization of the cyanide metabolizing enzyme rhodanese within olfactory mucosa. The Anatomical record. vol 232. issue 4. 1992-04-28. PMID:1554111. |
hypothesized roles include protection of the nasal epithelium, lung, and other downstream tissues, and termination or modification of olfactory responses. |
1992-04-28 |
2023-08-11 |
rat |
| S Biffo, L Verdun di Cantogno, A Fasol. Double labeling with non-isotopic in situ hybridization and BrdU immunohistochemistry: calmodulin (CaM) mRNA expression in post-mitotic neurons of the olfactory system. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 40. issue 4. 1992-04-27. PMID:1552187. |
to study the olfactory neuroepithelium, adult animals were injected with brdu, sacrificed after 30 days, and the nasal mucosa dissected and decalcified. |
1992-04-27 |
2023-08-11 |
rat |
| B P Menco, R C Bruch, B Dau, W Danh. Ultrastructural localization of olfactory transduction components: the G protein subunit Golf alpha and type III adenylyl cyclase. Neuron. vol 8. issue 3. 1992-04-24. PMID:1550671. |
these segments line the boundary between organism and external environment inside the olfactory part of the nasal cavity. |
1992-04-24 |
2023-08-11 |
rat |
| L M Zheng, D W Pfaff, M Schwanzel-Fukud. Electron microscopic identification of luteinizing hormone-releasing hormone-immunoreactive neurons in the medial olfactory placode and basal forebrain of embryonic mice. Neuroscience. vol 46. issue 2. 1992-04-08. PMID:1542414. |
as they leave the olfactory placode, they run under the epithelial layer of the nasal septum associated with vomeronasal and terminalis nerves. |
1992-04-08 |
2023-08-11 |
mouse |
| D A Leopold, D E Hornung, J E Schwo. Congenital lack of olfactory ability. The Annals of otology, rhinology, and laryngology. vol 101. issue 3. 1992-04-06. PMID:1543332. |
the clinical evaluation on these patients included a thorough medical and chemosensory history, physical examination, nasal endoscopy, chemosensory testing, olfactory biopsies, and imaging studies. |
1992-04-06 |
2023-08-11 |
Not clear |