| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard L Doty, Vanina Popova, Crystal Wylie, Maggie Fedgchin, Ella Daly, Adam Janik, Rachel Ochs-Ross, Rosanne Lane, Pilar Lim, Kim Cooper, Rama Melkote, Carol Jamieson, Jaskaran Singh, Wayne C Drevet. Effect of Esketamine Nasal Spray on Olfactory Function and Nasal Tolerability in Patients with Treatment-Resistant Depression: Results from Four Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase III Studies. CNS drugs. vol 35. issue 7. 2021-11-25. PMID:34235612. |
however, in some cases such delivery may be harmful to nasal and olfactory epithelia. |
2021-11-25 |
2023-08-13 |
Not clear |
| A Bhadury, U K Roy, T Ghosh, D Barman, P Manda. Assessment of Prescribing Pattern and Safety Profile of Drugs Used in Intranasal Route in Paediatric Age Group of Patients in a Tertiary Care Hospital. Kathmandu University medical journal (KUMJ). vol 19. issue 73. 2021-11-24. PMID:34812160. |
background recently there has been an increased preference for intranasal delivery of drugs due to highly vascular nasal mucosa, bypassing first pass metabolism and the blood brain barrier (bbb) lead in quick drug absorption to the systemic circulation and direct access to brain from olfactory region. |
2021-11-24 |
2023-08-13 |
Not clear |
| Marta Mariano, Tanja Drews, Thomas Humme. In healthy subjects nasal nitric oxide does not correlate with olfactory sensitivity, trigeminal sensitivity, and nasal airflow. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. vol 46. issue 6. 2021-11-22. PMID:34358412. |
in healthy subjects nasal nitric oxide does not correlate with olfactory sensitivity, trigeminal sensitivity, and nasal airflow. |
2021-11-22 |
2023-08-13 |
human |
| Marta Mariano, Tanja Drews, Thomas Humme. In healthy subjects nasal nitric oxide does not correlate with olfactory sensitivity, trigeminal sensitivity, and nasal airflow. Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery. vol 46. issue 6. 2021-11-22. PMID:34358412. |
the aim of the study was to determine the relationship between nasal nitric oxide (nno) and olfactory sensitivity, trigeminal sensitivity and nasal airflow in healthy subjects. |
2021-11-22 |
2023-08-13 |
human |
| Nicholas S Bates, Tarik F Massou. Ambiguous "olfactory" terms for anatomic spaces adjacent to the cribriform plate: A publication database analysis and quest for uniformity. Clinical anatomy (New York, N.Y.). vol 34. issue 8. 2021-11-22. PMID:34370888. |
we performed a publication database analysis to determine the frequency of misuse of names for seven anatomical "olfactory" spaces close to the cp and nasal cavity. |
2021-11-22 |
2023-08-13 |
Not clear |
| Nicholas S Bates, Tarik F Massou. Ambiguous "olfactory" terms for anatomic spaces adjacent to the cribriform plate: A publication database analysis and quest for uniformity. Clinical anatomy (New York, N.Y.). vol 34. issue 8. 2021-11-22. PMID:34370888. |
all 52 abstracts containing "olfactory" and "vestibule" were irrelevant, relating to the "nasal vestibule" and olfactory function, instead of "olfactory vestibule". |
2021-11-22 |
2023-08-13 |
Not clear |
| Abdullah AlMatrouk, Kayla Lemons, Tatsuya Ogura, Weihong Li. Modification of the Peripheral Olfactory System by Electronic Cigarettes. Comprehensive Physiology. vol 11. issue 4. 2021-11-18. PMID:34661289. |
the vast majority of flavorants in e-liquids are volatile odorants, and as such, the olfactory system plays a dominant role in perceiving these molecules that enter the nasal cavity either orthonasally or retronasally during vaping. |
2021-11-18 |
2023-08-13 |
human |
| Ceren Özeren Keşkek, Emre Aytuğa. Radiological Evaluation of Olfactory Fossa with Cone-Beam Computed Tomography. Journal of oral & maxillofacial research. vol 12. issue 3. 2021-11-17. PMID:34777725. |
the aim of this retrospective study was to evaluate the morphology of the olfactory fossa in the turkish population using cone-beam computed tomography according to keros classification and to investigate the effect of age, gender and nasal septum deviation on the olfactory fossa. |
2021-11-17 |
2023-08-13 |
Not clear |
| Yuko Mishima, Takako Osaki, Atsuyoshi Shimada, Shigeru Kamiya, Sanae Hasegawa-Ishi. Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice. Scientific reports. vol 11. issue 1. 2021-11-16. PMID:33633180. |
our previous studies indicated that chronic nasal inflammation caused loss of olfactory sensory neurons and gross atrophy of the olfactory bulb, which may lead to olfactory dysfunction. |
2021-11-16 |
2023-08-13 |
mouse |
| Joaquim Mullol, Claus Bachert, Nikhil Amin, Martin Desrosiers, Peter W Hellings, Joseph K Han, Roger Jankowski, Jan Vodicka, Philippe Gevaert, Nadia Daizadeh, Asif H Khan, Siddhesh Kamat, Naimish Patel, Neil M H Graham, Marcella Ruddy, Heribert Staudinger, Leda P Mannen. Olfactory Outcomes with Dupilumab in Chronic Rhinosinusitis with Nasal Polyps. The journal of allergy and clinical immunology. In practice. 2021-11-15. PMID:34628065. |
olfactory outcomes with dupilumab in chronic rhinosinusitis with nasal polyps. |
2021-11-15 |
2023-08-13 |
Not clear |
| Spiro Khoury, Volker Gudziol, Stéphane Grégoire, Stéphanie Cabaret, Susanne Menzel, Lucy Martine, Esther Mézière, Vanessa Soubeyre, Thierry Thomas-Danguin, Xavier Grosmaitre, Lionel Bretillon, Olivier Berdeaux, Niyazi Acar, Thomas Hummel, Anne Marie Le Bo. Lipidomic profile of human nasal mucosa and associations with circulating fatty acids and olfactory deficiency. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:34408170. |
lipidomic profile of human nasal mucosa and associations with circulating fatty acids and olfactory deficiency. |
2021-11-11 |
2023-08-13 |
human |
| Spiro Khoury, Volker Gudziol, Stéphane Grégoire, Stéphanie Cabaret, Susanne Menzel, Lucy Martine, Esther Mézière, Vanessa Soubeyre, Thierry Thomas-Danguin, Xavier Grosmaitre, Lionel Bretillon, Olivier Berdeaux, Niyazi Acar, Thomas Hummel, Anne Marie Le Bo. Lipidomic profile of human nasal mucosa and associations with circulating fatty acids and olfactory deficiency. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:34408170. |
the nasal mucosa (nm) contains olfactory mucosa which contributes to the detection of odorant molecules and the transmission of olfactory information to the brain. |
2021-11-11 |
2023-08-13 |
human |
| Spiro Khoury, Volker Gudziol, Stéphane Grégoire, Stéphanie Cabaret, Susanne Menzel, Lucy Martine, Esther Mézière, Vanessa Soubeyre, Thierry Thomas-Danguin, Xavier Grosmaitre, Lionel Bretillon, Olivier Berdeaux, Niyazi Acar, Thomas Hummel, Anne Marie Le Bo. Lipidomic profile of human nasal mucosa and associations with circulating fatty acids and olfactory deficiency. Scientific reports. vol 11. issue 1. 2021-11-11. PMID:34408170. |
correlation analysis revealed that the nasal aa level might be positively associated with olfactory deficiency. |
2021-11-11 |
2023-08-13 |
human |
| James J Doyle, Yasmeen Hashimie, Austin Mettin. An olfactory neuroblastoma presenting as posterior reversible leukoencephalopathy syndrome. Proceedings (Baylor University. Medical Center). vol 34. issue 6. 2021-11-05. PMID:34733002. |
olfactory neuroblastomas are rare malignancies of the nasal and sinus cavities. |
2021-11-05 |
2023-08-13 |
Not clear |
| Young Ah Lee, Kyeong Ah Kim, Myeong Heon Shi. Naegleria fowleri Induces Jurkat T Cell Death via O-deGlcNAcylation. The Korean journal of parasitology. vol 59. issue 5. 2021-11-03. PMID:34724770. |
the pathogenic free-living amoeba naegleria fowleri causes primary amoebic meningoencephalitis, a fatal infection, by penetrating the nasal mucosa and migrating to the brain via the olfactory nerves. |
2021-11-03 |
2023-08-13 |
Not clear |
| Lior Gorodisky, Ethan Livne, Tali Weiss, Aharon Weissbrod, Reut Weissgross, Eva Mishor, Edna Furman-Haran, Noam Sobe. Odor Canopy: A Method for Comfortable Odorant Delivery in MRI. Chemical senses. vol 46. 2021-11-01. PMID:33388762. |
moreover, we find that odor canopy is rated more comfortable than nasal mask, and we demonstrate that using odor canopy in the fmri generates a typical olfactory brain response. |
2021-11-01 |
2023-08-13 |
human |
| Bomin Son, Wesuk Kang, Soyoon Park, Dabin Choi, Taesun Par. Dermal Olfactory Receptor OR51B5 Is Essential for Survival and Collagen Synthesis in Human Dermal Fibroblast (Hs68 Cells). International journal of molecular sciences. vol 22. issue 17. 2021-10-29. PMID:34502185. |
olfactory receptors (ors) were initially considered to be specifically expressed in nasal tissue, but several ors have been reported to be present in other tissues, and their biological roles have recently received increasing attention. |
2021-10-29 |
2023-08-13 |
human |
| Raziyeh Najafloo, Jila Majidi, Alimohamad Asghari, Mina Aleemardani, Seyed Kamran Kamrava, Sara Simorgh, Amelia Seifalian, Zohreh Bagher, Alexander M Seifalia. Mechanism of Anosmia Caused by Symptoms of COVID-19 and Emerging Treatments. ACS chemical neuroscience. vol 12. issue 20. 2021-10-27. PMID:34609841. |
this paper covers all of the studies investigating olfactory disorders following covid-19 infection and explains the possible reasons for the correlated anosmia, including olfactory cleft syndrome, local inflammation in the nasal epithelium, early apoptosis of olfactory cells, changes in olfactory cilia and odor transmission, damage to microglial cells, effect on olfactory bulbs, epithelial olfactory injury, and impairment of olfactory neurons and stem cells. |
2021-10-27 |
2023-08-13 |
Not clear |
| Sanaa Harrass, Chenju Yi, Hui Che. Chronic Rhinosinusitis and Alzheimer's Disease-A Possible Role for the Nasal Microbiome in Causing Neurodegeneration in the Elderly. International journal of molecular sciences. vol 22. issue 20. 2021-10-26. PMID:34681867. |
evidence suggests a potential of β-amyloid deposition starting in olfactory neurons, which is then expanded from the nasal cavity to the central nervous system. |
2021-10-26 |
2023-08-13 |
human |
| C E Papadakis, T S Chimona, K Chaidas, A Ladias, M Zisoglou, E K Proimo. Effect of oral steroids on olfactory function in chronic rhinosinusitis with nasal polyps. European annals of otorhinolaryngology, head and neck diseases. vol 138. issue 5. 2021-10-25. PMID:33676882. |
effect of oral steroids on olfactory function in chronic rhinosinusitis with nasal polyps. |
2021-10-25 |
2023-08-13 |
Not clear |