| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dhondup Namgyal, Sher Ali, Rachna Mehta, Maryam Sarwa. The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway. Toxicology. vol 442. 2021-01-11. PMID:32735850. |
one of the major causative agents of neurotoxicity is a non-essential transition heavy metal, cadmium (cd), that reaches the central nervous system (cns) through the nasal mucosa and olfactory pathway causing adverse structural and functional effects. |
2021-01-11 |
2023-08-13 |
mouse |
| Mohammed A Albarki, Maureen D Donova. Bigger or Smaller? Size and Loading Effects on Nanoparticle Uptake Efficiency in the Nasal Mucosa. AAPS PharmSciTech. vol 21. issue 8. 2021-01-11. PMID:33099728. |
to better understand the size dependence of nasal epithelial uptake, plga nanoparticles (60 nm or 125 nm) loaded with nile red were prepared, and their uptake into excised sections of bovine nasal respiratory or olfactory mucosa was measured for 30 or 60 min. |
2021-01-11 |
2023-08-13 |
cattle |
| Yasamin A Jodat, Kiavash Kiaee, Daniel Vela Jarquin, Rosakaren Ludivina De la Garza Hernández, Ting Wang, Sudeep Joshi, Zahra Rezaei, Bruna Alice Gomes de Melo, David Ge, Manu S Mannoor, Su Ryon Shi. A 3D-Printed Hybrid Nasal Cartilage with Functional Electronic Olfaction. Advanced science (Weinheim, Baden-Wurttemberg, Germany). vol 7. issue 5. 2021-01-10. PMID:32154068. |
hybrid nasal organs can be equipped with remarkable capabilities such as augmented olfactory perception. |
2021-01-10 |
2023-08-13 |
human |
| Mengfei Chen, Wenjuan Shen, Nicholas R Rowan, Heather Kulaga, Alexander Hillel, Murugappan Ramanathan, Andrew P Lan. Elevated ACE2 expression in the olfactory neuroepithelium: implications for anosmia and upper respiratory SARS-CoV-2 entry and replication. bioRxiv : the preprint server for biology. 2021-01-10. PMID:32511390. |
we determined the cellular location of the sars-cov-2 target receptor protein, ace2, in the human upper airway, finding striking enrichment (200-700 folds) in the olfactory neuroepithelium relative to nasal respiratory or tracheal epithelial cells. |
2021-01-10 |
2023-08-13 |
human |
| Leigh Dairaghi, Ellen Flannery, Paolo Giacobini, Aybike Saglam, Hassan Saadi, Stephanie Constantin, Filippo Casoni, Brian W Howell, Susan Wra. Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway. Frontiers in cellular neuroscience. vol 12. 2021-01-09. PMID:30127721. |
prenatal migration of gnrh neurons from the nasal placode to the forebrain, juxtaposed to olfactory axons and olfactory ensheathing cells (oecs), has been well documented, and it is clear that alterations in migration of these cells can cause delayed or absent puberty. |
2021-01-09 |
2023-08-13 |
mouse |
| Scott Miners, Patrick G Kehoe, Seth Lov. Cognitive impact of COVID-19: looking beyond the short term. Alzheimer's research & therapy. vol 12. issue 1. 2021-01-07. PMID:33380345. |
limited data suggest that the causative sars-cov-2 virus may enter the cns via the nasal mucosa and olfactory fibres, or by haematogenous spread, and is capable of infecting endothelial cells, pericytes and probably neurons. |
2021-01-07 |
2023-08-13 |
Not clear |
| Maxime Bonnet, Gaëlle Guiraudie-Capraz, Tanguy Marqueste, Stéphane Garcia, Charlotte Jaloux, Patrick Decherchi, François Féro. Immediate or Delayed Transplantation of a Vein Conduit Filled with Nasal Olfactory Stem Cells Improves Locomotion and Axogenesis in Rats after a Peroneal Nerve Loss of Substance. International journal of molecular sciences. vol 21. issue 8. 2021-01-05. PMID:32290426. |
immediate or delayed transplantation of a vein conduit filled with nasal olfactory stem cells improves locomotion and axogenesis in rats after a peroneal nerve loss of substance. |
2021-01-05 |
2023-08-13 |
rat |
| Toshiyasu Sakane, Sachi Okabayashi, Shunsuke Kimura, Daisuke Inoue, Akiko Tanaka, Tomoyuki Furubayash. Brain and Nasal Cavity Anatomy of the Cynomolgus Monkey: Species Differences from the Viewpoint of Direct Delivery from the Nose to the Brain. Pharmaceutics. vol 12. issue 12. 2020-12-31. PMID:33352847. |
the nasal cavity was very narrow and the olfactory region was far from the nostrils, similar to rats and humans. |
2020-12-31 |
2023-08-13 |
rat |
| Shiv Bahadur, Dinesh M Pardhi, Jarkko Rautio, Jessica M Rosenholm, Kamla Patha. Intranasal Nanoemulsions for Direct Nose-to-Brain Delivery of Actives for CNS Disorders. Pharmaceutics. vol 12. issue 12. 2020-12-31. PMID:33352959. |
nasal drug delivery has gained significant interest for brain targeting over the past decades, wherein the drug is directly delivered to the brain by the trigeminal and olfactory pathway. |
2020-12-31 |
2023-08-13 |
Not clear |
| Mohammad Hazeri, Mohammad Faramarzi, Sasan Sadrizadeh, Goodarz Ahmadi, Omid Aboual. Regional deposition of the allergens and micro-aerosols in the healthy human nasal airways. Journal of aerosol science. vol 152. 2020-12-30. PMID:33100375. |
the nasal cavity is the inlet to the human respiratory system and is responsible for the olfactory sensation, filtering pollutant particulate matter, and humidifying the air. |
2020-12-30 |
2023-08-13 |
human |
| Seung-Jun Yoo, Gowoon Son, Jisub Bae, So Yeun Kim, Yong Kyoung Yoo, Dongsung Park, Seung Yeop Baek, Keun-A Chang, Yoo-Hun Suh, Yeong-Bae Lee, Kyo Seon Hwang, YoungSoo Kim, Cheil Moo. Longitudinal profiling of oligomeric Aβ in human nasal discharge reflecting cognitive decline in probable Alzheimer's disease. Scientific reports. vol 10. issue 1. 2020-12-21. PMID:32641719. |
despite clinical evidence indicating a close relationship between olfactory dysfunction and alzheimer's disease (ad), further investigations are warranted to determine the diagnostic potential of nasal surrogate biomarkers for ad. |
2020-12-21 |
2023-08-13 |
human |
| Fangshu Yao, Yuting Ye, Wen Zho. Nasal airflow engages central olfactory processing and shapes olfactory percepts. Proceedings. Biological sciences. vol 287. issue 1937. 2020-12-16. PMID:33109009. |
nasal airflow engages central olfactory processing and shapes olfactory percepts. |
2020-12-16 |
2023-08-13 |
human |
| Fangshu Yao, Yuting Ye, Wen Zho. Nasal airflow engages central olfactory processing and shapes olfactory percepts. Proceedings. Biological sciences. vol 287. issue 1937. 2020-12-16. PMID:33109009. |
binding of airborne odour molecules to olfactory receptors at the top of the nasal cavity gives rise to our rich olfactory experience. |
2020-12-16 |
2023-08-13 |
human |
| Fangshu Yao, Yuting Ye, Wen Zho. Nasal airflow engages central olfactory processing and shapes olfactory percepts. Proceedings. Biological sciences. vol 287. issue 1937. 2020-12-16. PMID:33109009. |
our findings indicate that nasal flow spontaneously engages central olfactory processing and serves as an integral part of the olfactory percept in humans. |
2020-12-16 |
2023-08-13 |
human |
| Kristi Biswas, Brett Wagner Mackenzie, Charlotte Ballauf, Julia Draf, Richard G Douglas, Thomas Humme. Loss of bacterial diversity in the sinuses is associated with lower smell discrimination scores. Scientific reports. vol 10. issue 1. 2020-12-15. PMID:33009469. |
the aim of this study was to explore the link between olfactory dysfunction and nasal bacterial communities. |
2020-12-15 |
2023-08-13 |
human |
| Gaelle Vofo, Ronit Brodie, Menachem Gros. Nasal lavage containing Angiotensin-Converting Enzyme-2 agonist can prevent and reduce viral load in COVID-19. Medical hypotheses. vol 144. 2020-12-14. PMID:33254514. |
reports have also stated that the nasal and olfactory mucosa are overloaded with these receptors. |
2020-12-14 |
2023-08-13 |
Not clear |
| Jingyi Yang, Xiaole Song, Yuting Lai, Weidong Zhao, Jiaying Zhou, Quan Liu, Wanpeng Li, Huankang Zhang, Huan Wang, Peng Shi, Hongmeng Yu, Xicai Sun, Dehui Wan. Development and validation of a postoperative nomogram for predicting overall survival after endoscopic surgical management of olfactory neuroblastoma. EClinicalMedicine. vol 29-30. 2020-12-12. PMID:33305194. |
olfactory neuroblastoma (onb) is a rare malignancy arising in the nasal vault. |
2020-12-12 |
2023-08-13 |
Not clear |
| Ronak Reshamwala, Megha Shah, Lucy Belt, Jenny A K Ekberg, James A St Joh. Reliable cell purification and determination of cell purity: crucial aspects of olfactory ensheathing cell transplantation for spinal cord repair. Neural regeneration research. vol 15. issue 11. 2020-12-11. PMID:32394949. |
olfactory ensheathing cells can be harvested either from the lamina propria beneath the neuroepithelium in the nasal cavity, or from the olfactory bulb in the brain. |
2020-12-11 |
2023-08-13 |
Not clear |
| Qi Zhou, Zijian Li, Bei Liu, Long Zhao, Baohong Tian, Lina Wang, Yaming X. Occult olfactory neuroblastoma presenting with multiple bone metastases: a case report. Medicine. vol 99. issue 48. 2020-12-08. PMID:33235061. |
olfactory neuroblastoma (onb) is a rare malignant tumor of the nasal cavity, the primary local symptoms are usually inconspicuous. |
2020-12-08 |
2023-08-13 |
Not clear |
| Jianyang Liu, Yan Huang, Jialin He, Yi Zhuo, Wei Chen, Lite Ge, Da Duan, Ming Lu, Zhiping H. Olfactory Mucosa Mesenchymal Stem Cells Ameliorate Cerebral Ischemic/Reperfusion Injury Through Modulation of UBIAD1 Expression. Frontiers in cellular neuroscience. vol 14. 2020-12-08. PMID:33281557. |
olfactory mucosa mscs (om-mscs), a novel source of mscs located in the human nasal cavity, are easy to obtain and situated for autologous transplantation. |
2020-12-08 |
2023-08-13 |
human |