| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Pothos, P Rada, G P Mark, B G Hoebe. Dopamine microdialysis in the nucleus accumbens during acute and chronic morphine, naloxone-precipitated withdrawal and clonidine treatment. Brain research. vol 566. issue 1-2. 1992-06-23. PMID:1814554. |
this study shows the effect of opiate withdrawal on dopamine (da) in the nucleus accumbens (nac). |
1992-06-23 |
2023-08-11 |
rat |
| Y Takamatsu, H Yamamoto, O O Ogunremi, I Matsuzaki, T Moroj. The effects of corticotropin-releasing hormone on peptidergic neurons in the rat forebrain. Neuropeptides. vol 20. issue 4. 1992-06-11. PMID:1687480. |
the icv administration of 1 and 10 micrograms crh caused a marked reduction in cck-like immunoreactivity (cck-li), npy-li and som-li in the medial frontal cortex (mfc) and anterior cingulate cortex (ant.cc), whereas it induced an increment of npy-li in the nucleus accumbens (nac) and striatum. |
1992-06-11 |
2023-08-11 |
rat |
| G P Mark, P Rada, E Pothos, B G Hoebe. Effects of feeding and drinking on acetylcholine release in the nucleus accumbens, striatum, and hippocampus of freely behaving rats. Journal of neurochemistry. vol 58. issue 6. 1992-06-04. PMID:1573406. |
extracellular levels of acetylcholine (ach) were measured in the nucleus accumbens (nac), striatum (str), and hippocampus (hipp) using microdialysis in 30-min intervals before, during, and after free-feeding in 20-h food-deprived rats. |
1992-06-04 |
2023-08-11 |
rat |
| G S Robertson, J G Pfaus, L J Atkinson, H Matsumura, A G Phillips, H C Fibige. Sexual behavior increases c-fos expression in the forebrain of the male rat. Brain research. vol 564. issue 2. 1992-06-04. PMID:1810635. |
psychomotor stimulants increase the release of dopamine from the terminals of nigrostriatal and mesolimbic neurons and enhance fos immunoreactivity in the striatum and nucleus accumbens (nac). |
1992-06-04 |
2023-08-11 |
rat |
| P Rada, E Pothos, G P Mark, B G Hoebe. Microdialysis evidence that acetylcholine in the nucleus accumbens is involved in morphine withdrawal and its treatment with clonidine. Brain research. vol 561. issue 2. 1992-04-24. PMID:1802350. |
this study used microdialysis to measure changes in extracellular acetylcholine (ach) content in the nucleus accumbens (nac) of freely moving rats during acute and chronic morphine treatment, and following naloxone-precipitated withdrawal. |
1992-04-24 |
2023-08-11 |
rat |
| G G Nomikos, A P Zis, G Damsma, H C Fibige. Effects of chronic electroconvulsive shock on interstitial concentrations of dopamine in the nucleus accumbens. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1724565. |
the present experiments investigated the effects of acute and chronic ecs on interstitial concentrations of dopamine (da) in the nucleus accumbens (nac) using in vivo microdialysis in awake freely moving rats. |
1992-04-07 |
2023-08-11 |
rat |
| L Hernandez, N A Guzman, B G Hoebe. Bidirectional microdialysis in vivo shows differential dopaminergic potency of cocaine, procaine and lidocaine in the nucleus accumbens using capillary electrophoresis for calibration of drug outward diffusion. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796132. |
this suggests that in vivo about 68 nmol cocaine diffused into the nucleus accumbens (nac) during the 20 min. |
1992-04-07 |
2023-08-11 |
rat |
| J A Stamford, R Muscat, J J O'Connor, J Patel, S J Trout, W J Wieczorek, Z L Kruk, P Willne. Voltammetric evidence that subsensitivity to reward following chronic mild stress is associated with increased release of mesolimbic dopamine. Psychopharmacology. vol 105. issue 2. 1992-04-07. PMID:1796133. |
dopamine (da) release in the nucleus accumbens (nac) and caudate putamen (cpu) was measured in vivo using fast cyclic voltammetry, following electrical stimulation of the medial forebrain bundle. |
1992-04-07 |
2023-08-11 |
rat |
| H Nakamura, T Moroji, S Nohara, H Nakamura, A Okad. Activation of cerebral dopaminergic systems by noise and whole-body vibration. Environmental research. vol 57. issue 1. 1992-03-20. PMID:1740092. |
noise and whole-body vibration increased both cor and da turnover rates (shown by an increase of homovanillic acid (hva) and/or hva/da ratio) in the frontal cortex (fc) and the nucleus accumbens (nac). |
1992-03-20 |
2023-08-11 |
rat |
| J L Cadet, K Kujirai, S Przedborsk. Bilateral modulation of [3H]neurotensin binding by unilateral intrastriatal 6-hydroxydopamine injections: evidence from a receptor autoradiographic study. Brain research. vol 564. issue 1. 1992-03-12. PMID:1663814. |
intrastriatal injections of 6-hydroxydopamine which cause almost complete destruction of the mesostriatal dopaminergic pathway also caused a marked loss of neurotensin receptors in the caudate-putamen (cpu), the nucleus accumbens (nac) and in the olfactory tubercle (ot). |
1992-03-12 |
2023-08-11 |
rat |
| C A Leslie, M W Robertson, A J Cutler, J P Bennet. Postnatal development of D1 dopamine receptors in the medial prefrontal cortex, striatum and nucleus accumbens of normal and neonatal 6-hydroxydopamine treated rats: a quantitative autoradiographic analysis. Brain research. Developmental brain research. vol 62. issue 1. 1992-02-12. PMID:1836980. |
the postnatal development of dopamine (da) d1 receptors in the medial prefrontal cortex (mpfc), striatum (str) and nucleus accumbens (nac) of control and perinatally 6-hydroxydopamine (6-ohda) lesioned rats was examined using quantitative autoradiography of 3h-sch 23390 binding. |
1992-02-12 |
2023-08-11 |
rat |
| J A Angulo, H Coirini, M Ledoux, M Schumache. Regulation by dopaminergic neurotransmission of dopamine D2 mRNA and receptor levels in the striatum and nucleus accumbens of the rat. Brain research. Molecular brain research. vol 11. issue 2. 1992-02-06. PMID:1661813. |
by day 8 of haloperidol treatment, d2 mrna and receptor levels were decreased (up to 20%) in the medial and anterior aspects of the caudate-putamen (mcpu and acpu) and the nucleus accumbens (nac). |
1992-02-06 |
2023-08-11 |
rat |
| P Rada, G P Mark, E Pothos, B G Hoebe. Systemic morphine simultaneously decreases extracellular acetylcholine and increases dopamine in the nucleus accumbens of freely moving rats. Neuropharmacology. vol 30. issue 10. 1992-02-04. PMID:1758589. |
microdialysis was used to measure extracellular levels of acetylcholine (ach) and dopamine (da) simultaneously in the nucleus accumbens (nac) of freely moving rats. |
1992-02-04 |
2023-08-11 |
rat |
| P A Johansen, X T Hu, F J Whit. Relationship between D1 dopamine receptors, adenylate cyclase, and the electrophysiological responses of rat nucleus accumbens neurons. Journal of neural transmission. General section. vol 86. issue 2. 1992-01-02. PMID:1683241. |
the electrophysiological effects of three selective d1 dopamine (da) receptor agonists, which exhibit different potencies and efficacies for stimulation of adenylate cyclase, were compared in the rat nucleus accumbens (nac) using single unit recording and microiontophoretic techniques. |
1992-01-02 |
2023-08-11 |
rat |
| Q Yang, T Moroji, Y Takamatsu, Y Hagino, M Okuw. The effects of intraperitoneally administered phencyclidine on the central nervous system: behavioral and neurochemical studies. Neuropeptides. vol 19. issue 2. 1991-12-12. PMID:1944826. |
ip injection of pcp caused a dose-related increase in the levels of da and 3,4-dihydroxy-phenylacetic acid (dopac) in the medial frontal cortex (mfc) and anterior cingulate cortex (ant.cc) without any changes in the nucleus accumbens (nac) or striatum. |
1991-12-12 |
2023-08-11 |
rat |
| D J Henry, F J Whit. Repeated cocaine administration causes persistent enhancement of D1 dopamine receptor sensitivity within the rat nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 258. issue 3. 1991-10-17. PMID:1890623. |
the rewarding effects of cocaine are mediated primarily by the mesoaccumbens dopamine (da) system, which projects from a10 da cell bodies within the ventral tegmental area to the nucleus accumbens (nac). |
1991-10-17 |
2023-08-11 |
rat |
| R Spanagel, A Herz, R Bals-Kubik, T S Shippenber. Beta-endorphin-induced locomotor stimulation and reinforcement are associated with an increase in dopamine release in the nucleus accumbens. Psychopharmacology. vol 104. issue 1. 1991-09-30. PMID:1882003. |
in vivo microdialysis was used to compare the effects of beta-endorphin upon dopamine (da) release in the nucleus accumbens (nac) of anesthetized versus freely moving rats, and to examine the role of the mesolimbic da system in mediating both the motoric and secondary reinforcing effects of this peptide. |
1991-09-30 |
2023-08-11 |
rat |
| R Z Terwilliger, D Beitner-Johnson, K A Sevarino, S M Crain, E J Nestle. A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1651140. |
we found that while most regions showed no regulation in response to chronic morphine, nucleus accumbens (nac) and amygdala did show increases in adenylate cyclase and cyclic amp-dependent protein kinase activity, and thalamus showed an increase in cyclic amp-dependent protein kinase activity only. |
1991-09-19 |
2023-08-11 |
rat |
| D Beitner-Johnson, E J Nestle. Morphine and cocaine exert common chronic actions on tyrosine hydroxylase in dopaminergic brain reward regions. Journal of neurochemistry. vol 57. issue 1. 1991-07-23. PMID:1675665. |
we studied levels of tyrosine hydroxylase immunoreactivity and phosphorylation state in the ventral tegmental area (vta) and nucleus accumbens (nac) in an effort to understand better the mechanisms by which these brain reward regions are influenced by opiates and cocaine. |
1991-07-23 |
2023-08-11 |
Not clear |
| C H West, R P Michae. Substance P injections into the ventral tegmentum affect unit activity in mesolimbic terminal regions. Brain research bulletin. vol 26. issue 2. 1991-05-16. PMID:1707328. |
there were mostly decreases in nucleus accumbens (nac, 21 of 25 units affected by sp) and mostly increases in olfactory tubercle (ot, 13 of 18 units affected by sp). |
1991-05-16 |
2023-08-11 |
rat |