| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Arango, M D Underwood, A V Gubbi, J J Man. Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims. Brain research. vol 688. issue 1-2. 1996-02-14. PMID:8542298. |
quantitative autoradiography was performed in coronal sections of prefrontal cortex to determine whether serotonin 5-ht1a receptor (postsynaptic in cortex) and serotonin transporter (presynaptic) binding are different in suicide victims compared to matched controls. |
1996-02-14 |
2023-08-12 |
Not clear |
| G A Gudelsky, J F Nas. Carrier-mediated release of serotonin by 3,4-methylenedioxymethamphetamine: implications for serotonin-dopamine interactions. Journal of neurochemistry. vol 66. issue 1. 1996-01-24. PMID:8522960. |
mdma produced a dose-dependent increase in the extracellular concentration of 5-ht in the striatum and prefrontal cortex that was attenuated by treatment with fluoxetine but not by tetrodotoxin. |
1996-01-24 |
2023-08-12 |
rat |
| G Tanda, R Frau, G Di Chiar. Local 5HT3 receptors mediate fluoxetine but not desipramine-induced increase of extracellular dopamine in the prefrontal cortex. Psychopharmacology. vol 119. issue 1. 1995-10-19. PMID:7675944. |
fluoxetine and desipramine, two antidepressants that block selectively the serotonin and the noradrenaline carrier, increase extracellular dopamine concentrations in the prefrontal cortex of freely-moving rats. |
1995-10-19 |
2023-08-12 |
rat |
| G Tanda, R Frau, G Di Chiar. Local 5HT3 receptors mediate fluoxetine but not desipramine-induced increase of extracellular dopamine in the prefrontal cortex. Psychopharmacology. vol 119. issue 1. 1995-10-19. PMID:7675944. |
fluoxetine, but not desipramine, increases extracellular serotonin concentrations in the prefrontal cortex. |
1995-10-19 |
2023-08-12 |
rat |
| G Tanda, R Frau, G Di Chiar. Local 5HT3 receptors mediate fluoxetine but not desipramine-induced increase of extracellular dopamine in the prefrontal cortex. Psychopharmacology. vol 119. issue 1. 1995-10-19. PMID:7675944. |
the results indicate that selective serotonin reuptake blockers increase extracellular dopamine in the prefrontal cortex by stimulating local 5-ht3 receptors. |
1995-10-19 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, H Sait. Effects of conditioned fear stress on 5-HT release in the rat prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 51. issue 2-3. 1995-10-11. PMID:7667378. |
effects of conditioned fear stress on 5-ht release in the rat prefrontal cortex. |
1995-10-11 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, H Sait. Effects of conditioned fear stress on 5-HT release in the rat prefrontal cortex. Pharmacology, biochemistry, and behavior. vol 51. issue 2-3. 1995-10-11. PMID:7667378. |
these findings suggest that there is a relationship between anxiety and 5-ht release in the prefrontal cortex and that the 5-ht3 receptor antagonist tropisetron might have anxiolytic properties. |
1995-10-11 |
2023-08-12 |
rat |
| T H Svensson, J M Mathé, J L Andersson, G G Nomikos, B E Hildebrand, M Marcu. Mode of action of atypical neuroleptics in relation to the phencyclidine model of schizophrenia: role of 5-HT2 receptor and alpha 1-adrenoceptor antagonism [corrected]. Journal of clinical psychopharmacology. vol 15. issue 1 Suppl 1. 1995-05-31. PMID:7730496. |
the administration of high doses of ritanserin or atypical neuroleptics with prominent serotonin (5-hydroxytrypyamine) 5-ht2 receptor antagonist action, such as clozapine or amperozide, produced preferential activation of the pfc da projection. |
1995-05-31 |
2023-08-12 |
rat |
| P D Shabanov, A A Lebede. [The dopaminergic and serotoninergic components of the self-stimulation reaction of the lateral hypothalamus in rats with disruption of the medial prefrontal cortex]. Fiziologicheskii zhurnal imeni I.M. Sechenova. vol 80. issue 11. 1995-05-22. PMID:7536553. |
an unipolar lesion of medical prefrontal cortex with kainic acid 10-14 days prior to an experiment did not prevent the facilitating effect of amphetamine on self-stimulation, though the levels of hypothalamic noradrenaline and dopamine are 43% and 4.5-fold decreased respectively, the hypothalamic serotonin concentration not changing. |
1995-05-22 |
2023-08-12 |
rat |
| H Tanila, T Taira, T P Piepponen, A Honkane. Effect of sex and age on brain monoamines and spatial learning in rats. Neurobiology of aging. vol 15. issue 6. 1995-04-18. PMID:7891829. |
the concentrations of noradrenaline (na), dopamine (da), serotonin (5-ht), and their metabolites were measured in the prefrontal cortex, caudate-putamen, and hippocampus in young (3 months) and aged (27-31 months) wistar rats of both sexes. |
1995-04-18 |
2023-08-12 |
rat |
| b' L Smejkal-Jagar, M Borani\\xc4\\x8. Serotonin, serotoninergic agents and their antagonists suppress humoral immune reaction in vitro. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 194. issue 5. 1995-03-15. PMID:7855445.' |
serotonin (5-ht), its derivative 5-methoxy-tryptamine (meot) and ergot-alkaloid dihydroergosine (dhesn) suppressed the immune reaction of mouse spleen cells against sheep erythrocytes in vitro (pfc assay). |
1995-03-15 |
2023-08-12 |
mouse |
| b' L Smejkal-Jagar, M Borani\\xc4\\x8. Serotonin, serotoninergic agents and their antagonists suppress humoral immune reaction in vitro. Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie. vol 194. issue 5. 1995-03-15. PMID:7855445.' |
it is concluded that serotonin and related agents probably affect several types of immunocompetent cells participating in successive stages of the pfc reaction. |
1995-03-15 |
2023-08-12 |
mouse |
| D C Ohuoha, T M Hyde, J E Kleinma. The role of serotonin in schizophrenia: an overview of the nomenclature, distribution and alterations of serotonin receptors in the central nervous system. Psychopharmacology. vol 112. issue 1 Suppl. 1995-02-22. PMID:7831440. |
the most promising findings involve a reduction in 5-ht2 receptors and 5-ht reuptake sites in the prefrontal cortex of schizophrenic patients. |
1995-02-22 |
2023-08-12 |
Not clear |
| A Rex, H Fink, C A Marsde. Effects of BOC-CCK-4 and L 365.260 on cortical 5-HT release in guinea-pigs on exposure to the elevated plus maze. Neuropharmacology. vol 33. issue 3-4. 1994-12-30. PMID:7527129. |
in the present microdialysis study exposure of the guinea-pig to the elevated plus maze increased extracellular 5-ht in the lateral prefrontal cortex. |
1994-12-30 |
2023-08-12 |
rat |
| R J Carey, E N Damianopoulo. Conditioned cocaine induced hyperactivity: an association with increased medial prefrontal cortex serotonin. Behavioural brain research. vol 62. issue 2. 1994-12-07. PMID:7945968. |
importantly, the analysis for serotonin revealed higher levels of 5-ht and 5-hiaa selectively in the prefrontal cortex. |
1994-12-07 |
2023-08-12 |
rat |
| R N Iyer, J S Sprouse, G K Aghajanian, R H Roth, C W Bradberr. Tryptophan pretreatment augmentation of p-chloroamphetamine-induced serotonin and dopamine release and reduction of long-term neurotoxicity. Biochemical pharmacology. vol 48. issue 7. 1994-11-23. PMID:7945451. |
trp pretreatment (400 mg/kg of the methyl ester) significantly reduced the long-term (1 week) decrease in tissue 5-ht resulting from pca (2 mg/kg, i.p., of the hydrochloride salt) in the prefrontal cortex and striatum, but not in the dorsal hippocampus. |
1994-11-23 |
2023-08-12 |
Not clear |
| Z Binienda, C M Fogle, W Slikker, S F Al. Acute effects of perinatal hypoxic insult on concentrations of dopamine, serotonin, and metabolites in fetal monkey brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 2. 1994-11-10. PMID:7524270. |
in prefrontal cortex, there was a trend toward an increase in serotonin but no effects on dopamine and homovanillic acid concentrations. |
1994-11-10 |
2023-08-12 |
monkey |
| A M Gardier, S Kachaner, E Kahn Shaghaghi, C Blot, C Bohuon, C Jacquot, M J Pallard. Effects of a primary immune response to T-cell dependent antigen on serotonin metabolism in frontal cortex: in vivo microdialysis study in freely moving Fischer 344 rat. Brain research. vol 645. issue 1-2. 1994-09-21. PMID:7520341. |
major decreases in 5-ht levels were evident in the hypothalamus (hy) and cortex (cx) at a time which corresponded to the late phase of the production of specific antibodies to srbc measured with a plaque-forming cell assay (pfc). |
1994-09-21 |
2023-08-12 |
rat |
| S Zalcman, J M Green-Johnson, L Murray, D M Nance, D Dyck, H Anisman, A H Greenber. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6. Brain research. vol 643. issue 1-2. 1994-08-12. PMID:7518332. |
in particular, il-1 enhanced ne turnover in the hypothalamus and hippocampus, 5-ht turnover in the hippocampus and prefrontal cortex (owing to increased utilization and reduced content of the transmitters in these brain regions), and enhanced da utilization in the prefrontal cortex. |
1994-08-12 |
2023-08-12 |
mouse |
| S Zalcman, J M Green-Johnson, L Murray, D M Nance, D Dyck, H Anisman, A H Greenber. Cytokine-specific central monoamine alterations induced by interleukin-1, -2 and -6. Brain research. vol 643. issue 1-2. 1994-08-12. PMID:7518332. |
il-6 increased 5-ht and da activity in the hippocampus and prefrontal cortex in a manner similar to il-1, but failed to affect central ne activity. |
1994-08-12 |
2023-08-12 |
mouse |