| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Evan L Nichols, Cody J Smit. Synaptic-like Vesicles Facilitate Pioneer Axon Invasion. Current biology : CB. vol 29. issue 16. 2020-08-03. PMID:31378609. |
we further show that the matrix metalloproteinase (mmp) mmp14a is required in pioneer axons to navigate across the boundary of the spinal cord and, with super-resolution microscopy, is positioned with synaptic vesicles at the boundary. |
2020-08-03 |
2023-08-13 |
zebrafish |
| Qingfeng Shen, Yangjing Cao, Yingpeng Xi. Atorvastatin attenuates spinal cord injury by chronic fluorosis in rats. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31651706. |
immunohistochemistry and western blotting revealed that compared with n group, matrix metalloproteinase 9 (mmp-9) and p53 were highly expressed and myelin basic protein (mbp) was low expressed in spinal cord of c group. |
2020-07-31 |
2023-08-13 |
rat |
| Rahim Heidari Barchi Nezhad, Fateme Asadi, Seyyed Meysam Abtahi Froushani, Gholamhossein Hassanshahi, Ayat Kaeidi, Soudeh Khanamani Falahati-Pour, Zahra Hashemi, Mohammad Reza Mirzae. The effects of transplanted mesenchymal stem cells treated with 17-b estradiol on experimental autoimmune encephalomyelitis. Molecular biology reports. vol 46. issue 6. 2020-04-15. PMID:31555971. |
the mrna expression of cytokines, including il-17, ifn-γ, tnf-α, il-10, il-4, and tgf-β together with mmp8 and mmp9 as the family members of matrix metalloproteinases (mmps) in the brain and spinal cord tissues were examined using real-time pcr. |
2020-04-15 |
2023-08-13 |
rat |
| Andrea Raspa, Edoardo Bolla, Claudia Cuscona, Fabrizio Gelai. Feasible stabilization of chondroitinase abc enables reduced astrogliosis in a chronic model of spinal cord injury. CNS neuroscience & therapeutics. vol 25. issue 1. 2020-04-06. PMID:29855151. |
usually, spinal cord injury (sci) develops into a glial scar containing extracellular matrix molecules including chondroitin sulfate proteoglycans (cspgs). |
2020-04-06 |
2023-08-13 |
Not clear |
| Marcus May, Bernd Denecke, Timm Schroeder, Magdalena Götz, Andreas Faissne. Cell tracking Biology open. vol 7. issue 7. 2019-11-20. PMID:30045859. |
previously, we have shown that the glycoprotein of the extracellular matrix (ecm) tenascin-c (tnc) modulates the expression territories of the patterning genes nkx6.1 and nkx2.2 in the developing ventral spinal cord, tunes the responsiveness of neural stem/progenitor cells towards the cytokines fgf2 and egf and thereby promotes astrocyte maturation. |
2019-11-20 |
2023-08-13 |
Not clear |
| Sangmin Lee, Hannah E Salapa, Michael C Levi. Localization of near-infrared labeled antibodies to the central nervous system in experimental autoimmune encephalomyelitis. PloS one. vol 14. issue 2. 2019-11-18. PMID:30768649. |
fluorescently labeled anti-heterogeneous nuclear ribonucleoprotein a1 antibodies persisted in the central nervous system of mice with experimental autoimmune encephalomyelitis, colocalized with matrix metalloproteinase activity, correlated with clinical disease and shifted rostrally within the spinal cord, consistent with experimental autoimmune encephalomyelitis being an ascending paralysis. |
2019-11-18 |
2023-08-13 |
mouse |
| Melissa R Wrobel, Harini G Sundararaghava. Biomaterial Cues to Direct a Pro-regenerative Phenotype in Macrophages and Schwann Cells. Neuroscience. vol 376. 2019-02-21. PMID:29462706. |
we have previously demonstrated that spinal cord matrix (scm) proteins and hyaluronic acid (ha) nanofibers mitigate chondroitin sulfate proteoglycan (cspg) inhibition and promote growth in peripheral neurons. |
2019-02-21 |
2023-08-13 |
Not clear |
| Albert M Chun. Calcitonin gene-related peptide (CGRP): role in peripheral nerve regeneration. Reviews in the neurosciences. vol 29. issue 4. 2018-10-31. PMID:29216010. |
research has shown that cgrp is an integral part in peripheral nerve regeneration by (1) suppressing tumor necrosis factor-α, (2) forming an initial nerve bridge by increasing fibroblast motility and extracellular matrix synthesis, (3) vascularizing the spinal cord injury site, and (4) inducing schwann cell (sc) proliferation. |
2018-10-31 |
2023-08-13 |
Not clear |
| V I Tsymbalyuk, V V Medvedyev, O A Rybachuk, V I Kozyavkin, N G Draguntsova, D G Nesterenk. [IMPACT OF XENOTRANSPLANTATION OF NEUROGENIC STEM CELLS IN COMPLEX WITH THE TISSUE MATRIX NEUROGELTM ON RESTORATION OF MOTOR FUNCTION OF A RAT SPINAL CORD AFTER EXPERIMENTAL SPINAL TRAUMA]. Klinichna khirurhiia. issue 1. 2018-10-30. PMID:30272923. |
the method of restorative treatment for experimental spinal cord trauma (sct), using implantation of synthetic matrix in combination of neurogenic stem cells, was introduced. |
2018-10-30 |
2023-08-13 |
rat |
| Feng Fu, Xiang Zhu, Zhe Qin, Jing-Jing Wang, Chao Xu, Li-Na Wang, Yue Tu, Sai Zhang, Rui-Xin Li, Xiao-Hong Li, Ming-Liang Zha. Differential degradation rate and underlying mechanism of a collagen/chitosan complex in subcutis, spinal cord and brain tissues of rat. Journal of materials science. Materials in medicine. vol 29. issue 4. 2018-09-18. PMID:29556804. |
the scaffolds were implanted into the subcutis, spinal cord and brain tissues of sd rats, the rate of degradation was assessed by continuous monitoring of weight loss, the pathological changes of target areas were observed by histological staining, and matrix metalloproteinase 9 (mmp-9) and lysozyme were detected at the rapid stage of degradation of the scaffolds. |
2018-09-18 |
2023-08-13 |
rat |
| Jee Y Lee, Won H Na, Hae Y Choi, Kwang H Lee, Bong G Ju, Tae Y Yun. Jmjd3 mediates blood-spinal cord barrier disruption after spinal cord injury by regulating MMP-3 and MMP-9 expressions. Neurobiology of disease. vol 95. 2018-02-27. PMID:27425890. |
the disruption of the blood-spinal cord barrier (bscb) by matrix metalloprotease (mmp) activation is a detrimental event that leads to blood cell infiltration, inflammation, and apoptosis, thereby contributing to permanent neurological disability after spinal cord injury (sci). |
2018-02-27 |
2023-08-13 |
Not clear |
| Fahim Atif, Megan C Prunty, Nefize Turan, Donald G Stein, Seema Yousu. Progesterone modulates diabetes/hyperglycemia-induced changes in the central nervous system and sciatic nerve. Neuroscience. vol 350. 2018-02-06. PMID:28315443. |
we assessed the expression of markers of angiogenesis (vascular endothelial growth factor (vegf)), inflammation (interleukin-6 (il-6)) and tissue injury (cd11b, ng2, cox2 and matrix metalloproteinase-2 (mmp-2)) in the brain, spinal cord and sciatic nerve. |
2018-02-06 |
2023-08-13 |
rat |
| Melissa R Wrobel, Harini G Sundararaghava. Positive and negative cues for modulating neurite dynamics and receptor expression. Biomedical materials (Bristol, England). vol 12. issue 2. 2017-12-12. PMID:28221164. |
drg growth was recorded on different adhesive substrates, including a novel, porcine-derived spinal cord matrix (scm). |
2017-12-12 |
2023-08-13 |
chicken |
| Ming Gao, Haoqian Zhang, Alpa Trivedi, Kiran V Mahasenan, Valerie A Schroeder, William R Wolter, Mark A Suckow, Shahriar Mobashery, Linda J Noble-Haeusslein, Mayland Chan. Selective Inhibition of MMP-2 Does Not Alter Neurological Recovery after Spinal Cord Injury. ACS chemical neuroscience. vol 7. issue 11. 2017-06-21. PMID:27551907. |
matrix metalloproteinase (mmp)-2 knockout (ko) mice show impaired neurological recovery after spinal cord injury (sci), suggesting that this proteinase is critical to recovery processes. |
2017-06-21 |
2023-08-13 |
mouse |
| Kazuya Yokota, Kazu Kobayakawa, Takeyuki Saito, Masamitsu Hara, Ken Kijima, Yasuyuki Ohkawa, Akihito Harada, Ken Okazaki, Kohei Ishihara, Shigeo Yoshida, Akira Kudo, Yukihide Iwamoto, Seiji Okad. Periostin Promotes Scar Formation through the Interaction between Pericytes and Infiltrating Monocytes/Macrophages after Spinal Cord Injury. The American journal of pathology. vol 187. issue 3. 2017-05-29. PMID:28082119. |
we herein demonstrate that the extracellular matrix protein periostin (postn) is a key player in scar formation after traumatic spinal cord injury (sci). |
2017-05-29 |
2023-08-13 |
mouse |
| Kazuhide Inou. Purinergic signaling in microglia in the pathogenesis of neuropathic pain. Proceedings of the Japan Academy. Series B, Physical and biological sciences. vol 93. issue 4. 2017-04-24. PMID:28413195. |
the p2x4 receptor (p2x4r), a subtype of ionotropic atp receptors, is upregulated in spinal microglia after nerve injury by several factors, including cc chemokine receptor ccr2, the extracellular matrix protein fibronectin in the spinal cord, interferon regulatory factor 8 (irf8) and irf5. |
2017-04-24 |
2023-08-13 |
Not clear |
| Wenli Chen, Houqing Lon. [Role of matrix metalloproteinases in regulating neurovascular unit affect the prognosis of chronic compression of spinal cord injury: current status]. Zhonghua wai ke za zhi [Chinese journal of surgery]. vol 53. issue 9. 2016-07-12. PMID:26654153. |
this paper discusses matrix metalloproteinase (mmp) impact on the stability of the neural vascular unit, by directly decomposing extracellular matrix, inducing the glial cell migration, activating angiogenesis, regulating function of blood spinal cord barrier, and put forward the mmp may be the key points in regulation of spinal cord neurovascular unit structure and function change to affect the outcome of chronic oppressive cervical spinal cord. |
2016-07-12 |
2023-08-13 |
Not clear |
| Yunjiao Zhu, Cynthia Soderblom, Michelle Trojanowsky, Do-Hun Lee, Jae K Le. Fibronectin Matrix Assembly after Spinal Cord Injury. Journal of neurotrauma. vol 32. issue 15. 2016-04-04. PMID:25492623. |
after spinal cord injury (sci), a fibrotic scar forms at the injury site that is best characterized by the accumulation of perivascular fibroblasts and deposition of the extracellular matrix protein fibronectin. |
2016-04-04 |
2023-08-13 |
human |
| Woojin Kim, Sun Kwang Ki. Neural circuit remodeling and structural plasticity in the cortex during chronic pain. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 1. 2016-01-25. PMID:26807017. |
although the role of neural circuit remodeling and structural synaptic plasticity in the 'pain matrix' cortices in chronic pain has been thought as a secondary epiphenomenon to altered nociceptive signaling in the spinal cord, progress in whole brain imaging studies on human patients and animal models has suggested a possibility that plastic changes in cortical neural circuits may actively contribute to chronic pain symptoms. |
2016-01-25 |
2023-08-13 |
human |
| Xiumei Xu, Yanlong X. [Clinical efficacy on neurogenic bladder after spinal cord injury treated with rehabilitation training and acupuncture-moxibustion]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 35. issue 7. 2015-11-12. PMID:26521577. |
to compare the differences in the clinical efficacy on neurogenic bladder after spinal cord injury (scd between the matrix needling technique combined with rehabilitation training and rehabilitation training in the patients. |
2015-11-12 |
2023-08-13 |
Not clear |