| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Cullen, P L Mario. Non-neoplastic liver disease associated with chronic ground squirrel hepatitis virus infection. Hepatology (Baltimore, Md.). vol 23. issue 6. 1996-08-13. PMID:8675146. |
serum levels of aspartate and alanine transaminases (ast and alt) were mildly elevated in samples from seven infected animals compared with seven control animals. |
1996-08-13 |
2023-08-12 |
Not clear |
| J Laurin, K D Lindor, J S Crippin, A Gossard, G J Gores, J Ludwig, J Rakela, D B McGil. Ursodeoxycholic acid or clofibrate in the treatment of non-alcohol-induced steatohepatitis: a pilot study. Hepatology (Baltimore, Md.). vol 23. issue 6. 1996-08-13. PMID:8675165. |
among the patients treated with clofibrate, no change from baseline was found in mean alt, aspartate transaminase (ast), ggt, bilirubin, triglycerides, and cholesterol, or in histological grade of steatosis, inflammation, or fibrosis after 12 months of treatment as compared with entry. |
1996-08-13 |
2023-08-12 |
Not clear |
| G V Gregorio, P Jara, L Hierro, C Diaz, A de la Vega, A Vegnente, R Iorio, F Bortolotti, C Crivellaro, L Zancan, H Daniels, B Portmann, G Mieli-Vergan. Lymphoblastoid interferon alfa with or without steroid pretreatment in children with chronic hepatitis B: a multicenter controlled trial. Hepatology (Baltimore, Md.). vol 23. issue 4. 1996-08-02. PMID:8666320. |
the majority (85 percent) had a baseline aspartate aminotransferase (ast) level < or = 100 iu/l. |
1996-08-02 |
2023-08-12 |
Not clear |
| M M Feele. Biomarkers for Great Lakes priority contaminants: halogenated aromatic hydrocarbons. Environmental health perspectives. vol 103 Suppl 9. 1996-07-10. PMID:8635442. |
for pcbs, the most likely biomarkers of effect included some form of alteration in lipid metabolism (serum triglyceride/cholesterol levels) and elevation of hepatic-related enzymes, aspartate aminotransferase (ast) and gamma-glutamyltransferase (ggt). |
1996-07-10 |
2023-08-12 |
human |
| R Guan, H S Ng, K M Fock, K Y Ho, I Yap, J Y Kang, W C Chow, C N Chew, C Ng, C J Te. Immunogenicity and safety of an inactivated hepatitis A vaccine amongst Singaporeans. The Southeast Asian journal of tropical medicine and public health. vol 26. issue 2. 1996-06-26. PMID:8629058. |
one hundred and forty healthy volunteers with normal alanine (alt) and aspartate (ast) transaminases and no previous exposure to hav, received three 1 ml doses (720 elisa units) of an inactivated hav vaccine (smithkline beechams biologicals) following a 0, 1, 6 months vaccination schedule. |
1996-06-26 |
2023-08-12 |
human |
| Y Bacq, O Zarka, J F Bréchot, N Mariotte, S Vol, J Tichet, J Weil. Liver function tests in normal pregnancy: a prospective study of 103 pregnant women and 103 matched controls. Hepatology (Baltimore, Md.). vol 23. issue 5. 1996-06-19. PMID:8621129. |
serum aspartate transaminase (ast) activity and total bile acid (tba) concentrations did not differ between pregnant and nonpregnant women. |
1996-06-19 |
2023-08-12 |
Not clear |
| M Iwai, T Shimaz. Exaggeration of acute liver damage by hepatic sympathetic nerves and circulating catecholamines in perfused liver of rats treated with D-galactosamine. Hepatology (Baltimore, Md.). vol 23. issue 3. 1996-06-07. PMID:8617432. |
the leakage of lactate dehydrogenase (ldh) and aspartate aminotransferase (ast) from the liver was used as markers of acute liver damage. |
1996-06-07 |
2023-08-12 |
rat |
| V E Kostrubsky, S G Wood, M D Bush, J Szakacs, W J Bement, P R Sinclair, E H Jeffery, J F Sinclai. Acute hepatotoxicity of acetaminophen in rats treated with ethanol plus isopentanol. Biochemical pharmacology. vol 50. issue 11. 1996-06-06. PMID:8615851. |
serum levels of aspartate aminotransferase (ast) and histological examination of liver slices were used to assess hepatotoxicity. |
1996-06-06 |
2023-08-12 |
rat |
| S Chopra, K K Pillai, S Z Husain, D K Gir. Propolis protects against doxorubicin-induced myocardiopathy in rats. Experimental and molecular pathology. vol 62. issue 3. 1996-06-04. PMID:8612723. |
serum creatine phosphokinase (ck), aspartate aminotransferase (ast), blood and tissue glutathione (gsh), and thiobarbituric acid reactive substances (tbars) in heart were estimated to assess the status of heart muscle. |
1996-06-04 |
2023-08-12 |
rat |
| R Adam, I Astarcioglu, J S Raccuia, B Ducot, M Reynes, H Bismut. Beneficial effects of Eurocollins as aortic flush for the procurement of human livers. Transplantation. vol 61. issue 5. 1996-05-23. PMID:8607171. |
there was no significant difference between the groups with peak transaminases aspartate aminotransferase (ast) and alanine aminotransferase, maximum value of serum bilirubin within 10 days following lt, incidence of primary nonfunction, need for retransplantation, and patient and graft survival at 1 month. |
1996-05-23 |
2023-08-12 |
human |
| F M Rollwagen, W C Gafney, N D Pacheco, T A Davis, T M Hickey, T B Nielsen, A S Rudolp. Multiple responses to administration of liposome-encapsulated hemoglobin (LEH): Effects on hematopoiesis and serum IL-6 levels. Experimental hematology. vol 24. issue 3. 1996-04-26. PMID:8599972. |
following intravenous administration of leh, 1) a serum spike of interleukin-6 (il-6) occurred in mice at 4-8 hours, with no elevation of il-1, tumor necrosis factor (tnf), or interferon-gamma (ifn-gamma); 2) the serum liver function enzymes sgot (ast, aspartate aminotransferase) and sgpt (alt, alanine aminotransferase) were elevated at 48 hours; 3) only a slight increase in serum antibody to bovine hemoglobin was observed; and 4) increased hematopoietic activity was observed in the spleen and bone marrow. |
1996-04-26 |
2023-08-12 |
mouse |
| C Barriault, J L Petit, M Gascon-Barré, P M Huet, I M Yousef, B Tuchwebe. Effect of phalloidin on cholestasis, hemodynamics, and microcirculation in isolated perfused rat liver. Hepatology (Baltimore, Md.). vol 23. issue 2. 1996-04-03. PMID:8591855. |
under these conditions, phalloidin did not induce liver cell cytolysis, as assessed by aspartate transaminase (ast) and lactate dehydrogenase (ldh) release in the perfusate effluent. |
1996-04-03 |
2023-08-12 |
rat |
| S Zeuzem, J M Schmidt, J H Lee, B Rüster, W K Rot. Effect of interferon alfa on the dynamics of hepatitis C virus turnover in vivo. Hepatology (Baltimore, Md.). vol 23. issue 2. 1996-04-03. PMID:8591865. |
simultaneous kinetic analysis of serum aminotransferases as surrogate markers of hepatocyte integrity revealed half lifes for the release of alanine aminotransferase (alt) and aspartate aminotransferase (ast) from hepatocytes of 4.7 +/- 3.8 and 3.0 +/- 3.5 days, respectively. |
1996-04-03 |
2023-08-12 |
human |
| T Dodurka, W Kraf. [Alanine aminotransferase (ALT), aspartate aminotransferase (AST), glutamate dehydrogenase (GLDH), alkaline phosphatase (AP) and gamma-glutamyltransferase (GGP) in intestinal diseases of dogs]. Berliner und Munchener tierarztliche Wochenschrift. vol 108. issue 7. 1996-04-01. PMID:8593145. |
[alanine aminotransferase (alt), aspartate aminotransferase (ast), glutamate dehydrogenase (gldh), alkaline phosphatase (ap) and gamma-glutamyltransferase (ggp) in intestinal diseases of dogs]. |
1996-04-01 |
2023-08-12 |
Not clear |
| B Hocher, R Zart, F Diekmann, T Slowinski, C Thöne-Reineke, J Lutz, C Baue. Protective effects of the mixed endothelin receptor antagonist bosentan in rats with CCL4-induced liver injury. Journal of cardiovascular pharmacology. vol 26 Suppl 3. 1996-03-28. PMID:8587341. |
hepatotoxicity was assessed by determination of serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast) and lactate dehydrogenase (ldh). |
1996-03-28 |
2023-08-12 |
rat |
| Y Vandenberghe, M Masson, B Palate, J Rob. Effect of folate supplementation on clinical chemistry and hematologic changes related to bidisomide administration in the rat. Drug and chemical toxicology. vol 18. issue 4. 1996-03-27. PMID:8586020. |
plasma and liver alanine aminotransferase (alt) and plasma aspartate aminotransferase (ast) levels were also reduced at this dose level. |
1996-03-27 |
2023-08-12 |
rat |
| T R Downs, R C Dage, J F Frenc. Reduction in endotoxin-induced organ dysfunction and cytokine secretion by a cyclic nitrone antioxidant. International journal of immunopharmacology. vol 17. issue 7. 1996-03-25. PMID:8586485. |
mdl 101,002 markedly decreased lps-induced liver and kidney damage as indicated by serum levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt) or urea and creatinine, respectively. |
1996-03-25 |
2023-08-12 |
rat |
| R G Thurman, W Gao, H D Connor, Y Adachi, R F Stachlewitz, Z Zhong, K T Knecht, B U Bradford, R P Mason, J J Lemaster. Role of Kupffer cells in failure of fatty livers following liver transplantation and alcoholic liver injury. Journal of gastroenterology and hepatology. vol 10 Suppl 1. 1996-03-25. PMID:8589336. |
in rats exposed to ethanol continuously via intragastric feeding for up to 4 weeks, gdcl3 treatment prevented elevation of aspartate aminotransferase (ast) and dramatically reduced the average hepatic pathological score. |
1996-03-25 |
2023-08-12 |
rat |
| M Morimoto, K Numata, K Tanak. Rat peripheral mononuclear cell thymidine kinase activity increases during liver regenerative processes after partial hepatectomy. Journal of gastroenterology and hepatology. vol 10. issue 6. 1996-03-19. PMID:8580409. |
this change paralleled plasma levels of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
1996-03-19 |
2023-08-12 |
rat |
| S Chen, S Morimoto, M Tamatani, K Fukuo, T Nakahashi, A Nishibe, B Jiang, T Ogihar. Calcitonin prevents CCl4-induced hydroperoxide generation and cytotoxicity possibly through C1b receptor in rat hepatocytes. Biochemical and biophysical research communications. vol 218. issue 3. 1996-03-12. PMID:8579606. |
addition of ccl4 to the cells concentration dependently increased intracellular production of hydroperoxides and release of aspartate aminotransferase (ast) and alanine aminotransferase (alt). |
1996-03-12 |
2023-08-12 |
rat |