| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Arbid, M M el-Habbak, M S Hanaf. Toxicological and biological studies on Japanese quails fed graded levels of furazolidone. Acta veterinaria Hungarica. vol 38. issue 4. 1991-08-02. PMID:2099613. |
hepatotoxicity was evidenced by an increase in serum aspartate aminotransferase (ast), alanine aminotransferase (alt) and alkaline phosphatase and a decrease in serum total protein, in addition to degenerative changes of the hepatocytes in fz-treated birds. |
1991-08-02 |
2023-08-11 |
Not clear |
| N Sheron, J Lau, H Daniels, J Goka, A Eddleston, G J Alexander, R William. Increased production of tumour necrosis factor alpha in chronic hepatitis B virus infection. Journal of hepatology. vol 12. issue 2. 1991-07-19. PMID:2051003. |
tnf production in unstimulated cells correlated with serum hbv dna level (r = 0.53, p = 0.02) but not with serum aspartate transaminase (ast) or histological activity. |
1991-07-19 |
2023-08-11 |
human |
| H Ishiyama, K Ogino, Y Shimomura, T Kanbe, T Hobar. Hepatotoxicity of diethyldithiocarbamate in rats. Pharmacology & toxicology. vol 67. issue 5. 1991-07-17. PMID:1965745. |
plasma aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities were markedly elevated 24 hr after subcutaneous administration of ddc and histologically, the liver showed submassive necrosis. |
1991-07-17 |
2023-08-11 |
rat |
| R L Cohen, M E Alves, J M Crawford, T McSwiggin, D A Chamber. Association of gingival crevicular fluid aspartate aminotransferase levels with histopathology during ligature-induced periodontitis in the beagle dog. Journal of dental research. vol 70. issue 6. 1991-07-17. PMID:2045580. |
previous investigations have shown a clear association between the presence of the enzyme aspartate aminotransferase (ast) in gingival crevicular fluid (gcf) and clinical evidence of periodontal disease in humans, as well as in the beagle dog model. |
1991-07-17 |
2023-08-11 |
human |
| E Lee, Y Miki, Y Furukawa, H Simizu, K Kariy. Selective release of glutathione transferase subunits from primary cultured rat hepatocytes by carbon tetrachloride and deoxycholic acid. Toxicology. vol 67. issue 3. 1991-07-16. PMID:2048128. |
glycyrrhizin, an antihepatotoxic agent, inhibited the release of both aspartate transaminase (ast) and gsh transferases induced by carbon tetrachloride or deoxycholic acid. |
1991-07-16 |
2023-08-11 |
rat |
| J D Wang, M Y Lai, J S Chen, J M Lin, J R Chiang, S J Shiau, W S Chan. Dimethylformamide-induced liver damage among synthetic leather workers. Archives of environmental health. vol 46. issue 3. 1991-07-01. PMID:2039271. |
in those workers who had normal alt values, there occurred still significantly higher mean alt and aspartate aminotransferase (ast) activities, especially among those who were not hbsag carriers. |
1991-07-01 |
2023-08-11 |
Not clear |
| H C Parodi, S Gutiérrez, M Lattanzi, R Martínez, L O Colombat. [Value of laboratory tests and echography in the diagnosis of biliary disease in the initial phase of acute pancreatitis]. Acta gastroenterologica Latinoamericana. vol 20. issue 3. 1991-07-01. PMID:2095097. |
the aim of this study was to investigate the usefulness of serum bilirubin, aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (aph) and real time ultrasonography (us) in distinguishing between gallstone and non gallstone related acute pancreatitis (a.p.). |
1991-07-01 |
2023-08-11 |
Not clear |
| A Salvaggio, M Periti, L Miano, M Tavanelli, D Marzorat. Body mass index and liver enzyme activity in serum. Clinical chemistry. vol 37. issue 5. 1991-06-24. PMID:1674452. |
the association between body mass index (bmi) and serum liver enzyme activity [gamma-glutamyltransferase (ggt), alanine aminotransferase (alt), and aspartate aminotransferase (ast)] was studied in 3167 subjects, 2373 men and 794 women. |
1991-06-24 |
2023-08-11 |
human |
| J Bayad, N Sabolovic, D Bagrel, J Magdalou, G Sies. Influence of the isolation method on the stability of differentiated phenotype in cultured rat hepatocytes. Journal of pharmacological methods. vol 25. issue 1. 1991-06-18. PMID:1851520. |
transferrin secretion and tyrosine aminotransferase (tat), alanine aminotransferase (alt), and microsomal epoxide hydrolase (meh) activities were stable in both edta- and collagenase-isolated hepatocytes, whereas albumin secretion, aspartate amino transferase (ast) activity, total cytochromes p-450 content, ia1 and iib1 p-450 isoenzymes, nadph-cytochrome p-450 reductase (ec 1.6.2.4) levels, and bilirubin glucuronidation decreased faster in collagenase-treated cells. |
1991-06-18 |
2023-08-11 |
rat |
| F B Daniel, M Robinson, J A Stober, N P Page, G R Olso. Ninety-day toxicity study of sodium monochloroacetate in Sprague-Dawley rats. Toxicology. vol 67. issue 2. 1991-06-14. PMID:2031251. |
hepatotoxicity was indicated by increases in the serum levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
1991-06-14 |
2023-08-11 |
rat |
| T A Knox, M M Kapla. Treatment of primary sclerosing cholangitis with oral methotrexate. The American journal of gastroenterology. vol 86. issue 5. 1991-06-12. PMID:2028943. |
the alkaline phosphatase value decreased from a mean (+/-sd) of 373 +/- 210 iu to 140 +/- 77 iu (p = 0.0008), the mean alanine aminotransferase (alt) from 115 +/- 74 to 76 +/- 79 u/l (p = 0.005), and the mean aspartate aminotransferase (ast) value from 88 +/- 37 to 57 +/- 40 u/l (p = 0.007). |
1991-06-12 |
2023-08-11 |
Not clear |
| U Nicolini, P Nicolaidis, Y Tannirandorn, N M Fisk, H Nasrat, C H Rodec. Fetal liver dysfunction in Rh alloimmunization. British journal of obstetrics and gynaecology. vol 98. issue 3. 1991-06-05. PMID:1673629. |
the liver enzymes, aspartate transaminase (ast), alanine transaminase (alt), gamma glutamyl transpeptidase (ggt) and alkaline phosphatase (alp), were measured in the blood of 25 fetuses with severe rh alloimmunization at the time of their first, second and third intravascular transfusions and in 17 comparison fetuses. |
1991-06-05 |
2023-08-11 |
Not clear |
| R Antrum, K Gorst, K Galvin, C Thornton, K Wynne, C Malata, C Ramsden, R Kester, I Hardin. A comparison of teicoplanin vs. cephradine and metronidazole in surgical prophylaxis: an interim analysis. Scandinavian journal of infectious diseases. Supplementum. vol 72. 1991-06-05. PMID:1982576. |
neither drug regimen produced any evidence of renal or hepatic damage, though the levels of three hepatocellular enzymes, aspartate aminotransferase (ast), alanine aminotransferase (alt) and gamma-glutamyl-transferase (ggt), were seen to be transiently elevated, peaking 7 days post-operatively. |
1991-06-05 |
2023-08-11 |
Not clear |
| A R Elbers, I J Visser, J Odink, J F Smeet. Changes in haematological and clinicochemical profiles in blood of apparently healthy slaughter pigs, collected at the farm and at slaughter, in relation to the severity of pathological-anatomical lesions. The veterinary quarterly. vol 13. issue 1. 1991-05-30. PMID:1673575. |
the effects are most pronounced for leucocyte concentration and for the activity of the enzymes creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast) and gamma-glutamyltransferase (gamma-gt). |
1991-05-30 |
2023-08-11 |
Not clear |
| K E Tymms, E M Beller, J Webb, L Schrieber, W W Buchana. Correlation between tests of muscle involvement and clinical muscle weakness in polymyositis and dermatomyositis. Clinical rheumatology. vol 9. issue 4. 1991-05-29. PMID:2088650. |
a correlation study was performed on the degree of muscle weakness in 36 patients with dermatomyositis and 69 with polymyositis in relation to muscle biopsy findings, electromyography (emg) abnormalities, and serum concentrations of creatine kinase (ck), aspartate aminotransferase (ast) and alanine aminotransferase (alt) enzymes. |
1991-05-29 |
2023-08-11 |
Not clear |
| I Voinikova, D Dochev, M Petkova, A Suzuk. Changes in serum enzyme activities in splanchnic ischemia shock. Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression. vol 31. issue 7. 1991-05-21. PMID:2088107. |
the serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities are significantly increased at the 24 hr following the i.v. |
1991-05-21 |
2023-08-11 |
rat |
| S Kojima, A Furukawa, M Kiyozumi, H Shimad. Comparative renal toxicity of metallothioneins with different cadmium/zinc ratios in rats. Toxicology letters. vol 56. issue 1-2. 1991-05-20. PMID:2017779. |
from determination of the urinary excretion of protein, aspartate aminotransferase (ast) and glucose, which are indices of cd-induced renal damage, the extent of the renal toxicity of the mts used here was in the order (1 cd/0zn)-mt = (2cd/1zn)-mt greater than (1cd/2zn)-mt greater than (1cd/6zn)-mt. |
1991-05-20 |
2023-08-11 |
rat |
| E C Borden, J J Rinehart, B E Storer, D L Trump, D M Paulnock, A P Teitelbau. Biological and clinical effects of interferon-beta ser at two doses. Journal of interferon research. vol 10. issue 6. 1991-05-20. PMID:2086672. |
statistically significant changes (p less than 0.05) occurred in granulocytes, lymphocytes, calcium, cholesterol, alkaline phosphatase, and aspartate transferase (ast); however, except for ast, overall clinical differences in the two doses were not great. |
1991-05-20 |
2023-08-11 |
Not clear |
| D A Chambers, P B Imrey, R L Cohen, J M Crawford, M E Alves, T A McSwiggi. A longitudinal study of aspartate aminotransferase in human gingival crevicular fluid. Journal of periodontal research. vol 26. issue 2. 1991-05-16. PMID:1826527. |
previous studies have shown that aspartate aminotransferase (ast), an established serum marker for cardiac and liver damage in humans, appears in elevated concentrations in samples of gingival crevicular fluid (gcf) from ligated vs. non-ligated teeth in beagle dogs and in elevated quantities in cross-sectional gcf sampling, adjusted for collection time, from human sites with clinical signs of past or present periodontal disease as compared to healthy sites. |
1991-05-16 |
2023-08-11 |
human |
| P B Imrey, J M Crawford, R L Cohen, M E Alves, T A McSwiggin, D A Chamber. A cross-sectional analysis of aspartate aminotransferase in human gingival crevicular fluid. Journal of periodontal research. vol 26. issue 2. 1991-05-16. PMID:1826528. |
previous investigation has shown that the concentration of aspartate aminotransferase (ast), an established serum marker for cardiac and liver damage in humans, is significantly elevated in samples of gingival crevicular fluid (gcf) from ligated teeth in beagle dogs. |
1991-05-16 |
2023-08-11 |
human |