| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Yoshikawa, L P Ruhr, W Flory, M I Banton, D Giamalva, D F Church, W A Pryo. Toxicity of polycyclic aromatic hydrocarbons. III. Effects of beta-naphthoflavone pretreatment on hepatotoxicity of compounds produced in the ozonation or NO2-nitration of phenanthrene and pyrene in rats. Veterinary and human toxicology. vol 29. issue 2. 1987-05-27. PMID:3576942. |
no increase in the level of aspartate aminotransferase (ast), alanine aminotransferase (alt) or sorbitol dehydrogenase (sdh) was seen in the pretreated rats 48 hr after the treatment. |
1987-05-27 |
2023-08-11 |
rat |
| L Müller, M Wilhel. Uptake and distribution of aluminium in rat hepatocytes and its effect on enzyme leakage and lactate formation. Toxicology. vol 44. issue 2. 1987-05-20. PMID:3564054. |
concomitantly, the leakage of lactate dehydrogenase (ldh), alanine aminotransferase (alt) and aspartate aminotransferase (ast) increased in the presence of al time- and concentration-dependently, but only to a moderate extent. |
1987-05-20 |
2023-08-11 |
rat |
| P E Hickman, W Silvester, A A Musk, G H McLellan, A Harri. Cardiac enzyme changes in myxedema coma. Clinical chemistry. vol 33. issue 4. 1987-05-18. PMID:3829411. |
a 74-year-old man with myxedema and hypothermia had increased activities in plasma of creatine kinase (ck; ec 2.7.3.2), aspartate aminotransferase (ast; ec 2.6.1.1), and lactate dehydrogenase (ld; ec 1.1.1.27) and increased proportions of ck-mb (up to 20% of total ck) and ld1 isoenzymes, but no clinical or investigational evidence of associated myocardial infarction. |
1987-05-18 |
2023-08-11 |
Not clear |
| V A Protsenko, V Z Kharchenko, Iu N Kolesnikov, I F Spitsyn, V E Egoryche. [Effect of kontrikal on the dynamics of proteolytic system indices in postischemic toxemia]. Farmakologiia i toksikologiia. vol 50. issue 1. 1987-05-13. PMID:2435573. |
it was shown in wistar male rats that the development of tourniquet shock was followed by an increase of proteolytic activity in the blood by 3 times, activity of aspartate aminotransferase (ast) by 3 times, that of alanine aminotransferase (alt) by 6 times, contents of urea and residual nitrogen by 2.5-3 times; level of alpha 1-protease inhibitor (alpha 1-pi) decreased by 4 times and that of alpha 2-macroglobulin (alpha 2mg) by 2.5 times. |
1987-05-13 |
2023-08-11 |
rat |
| M O Paz, F Brenes, P Karayiannis, T P Jowett, P J Scheuer, H C Thoma. Chronic hepatitis B virus infection. Viral replication and patterns of inflammatory activity: serological, clinical and histological correlations. Journal of hepatology. vol 3. issue 3. 1987-05-11. PMID:3549868. |
hbv dna positivity correlated with the presence of hepatitis b e antigen (hbeag, p less than 0.001) and aspartate transaminase (ast) levels (p less than 0.005). |
1987-05-11 |
2023-08-11 |
Not clear |
| C W Davy, P N Trennery, J G Edmunds, J F Altman, D A Eichle. Local myotoxicity of ketamine hydrochloride in the marmoset. Laboratory animals. vol 21. issue 1. 1987-04-29. PMID:3104668. |
an investigation of raised plasma aspartate aminotransferase (ast) in marmosets after intramuscular ketamine injection suggested a local myotoxicity. |
1987-04-29 |
2023-08-11 |
marmoset |
| F Okuno, M Arai, H Ishii, Y Shigeta, Y Ebihara, S Takagi, M Tsuchiy. Mild but prolonged elevation of serum angiotensin converting enzyme (ACE) activity in alcoholics. Alcohol (Fayetteville, N.Y.). vol 3. issue 6. 1987-04-22. PMID:3028446. |
in contrast to the rapid normalization of such enzymes as aspartate transaminase (ast), alanine transaminase (alt) and lactic dehydrogenase (ldh) which represent parenchymal liver cell injury, the activity of ace remained elevated over a period of 4 weeks even with abstinence. |
1987-04-22 |
2023-08-11 |
Not clear |
| G Kovác, P Mudron, M Prosbová, J Pasték. [Clinical and biochemical response in the prevention of nutritional myodystrophy in heifers]. Veterinarni medicina. vol 32. issue 2. 1987-04-14. PMID:3103311. |
sensitive indicators of the break-down of muscular tissue were the enzymes aspartate aminotransferase (ast), alanine aminotransferase (alt), and mainly creatinine kinase (cpk): the activities of these enzymes increased significantly after the heifers had been driven to pasture. |
1987-04-14 |
2023-08-11 |
cattle |
| T Yoshikawa, W Flory, L P Ruhr, D Giamalva, D F Church, W A Pryo. Toxicity of polycyclic aromatic hydrocarbons. II. Effect of NO2-nitrated phenanthrene and pyrene on blood chemistry in rats. Veterinary and human toxicology. vol 29. issue 1. 1987-04-02. PMID:3824871. |
phenanthrene produced a significant elevation of serum aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels relative to dmso-injected rats 24 hr after injection. |
1987-04-02 |
2023-08-11 |
rat |
| M Panteghini, F Pagani, C Cucci. Activity of serum aspartate aminotransferase isoenzymes in patients with acute myocardial infarction. Clinical chemistry. vol 33. issue 1. 1987-02-26. PMID:3802498. |
activities of aspartate aminotransferase (ast) isoenzymes were determined in serial serum samples from 40 cases of acute myocardial infarction, and compared with activities of creatine kinase, ck-mb isoenzyme, lactate dehydrogenase, and alpha-hydroxybutyrate dehydrogenase for temporal changes. |
1987-02-26 |
2023-08-11 |
Not clear |
| A Kovacs, L Chan, C Hotrakitya, G Overturf, B Portno. Serum transaminase elevations in infants with rotavirus gastroenteritis. Journal of pediatric gastroenterology and nutrition. vol 5. issue 6. 1987-02-19. PMID:3794904. |
on admission, rtz-positive (rtz+) infants had higher mean and median alanine aminotransferase (alt) levels [mean 87.5 u/l in rtz+ vs. 50.0 u/l in rtz-negative (rtz-), p = 0.001; medium 60 u/l in rtz+ vs. 41 u/l in rtz- infants, p = 0.002], and higher mean and median aspartate aminotransferase (ast) levels (mean 64.3 u/l in rtz+ vs. 44.0 u/l in rtz- infants, p = 0.008; median 67.5 u/l vs. 42.0 u/l, respectively, p = less than 0.05). |
1987-02-19 |
2023-08-11 |
human |
| T Moriyama, T Ashiie, K Kikuiri, Y Nishiyama, Y Ito, M Nobuoka, M Makin. Mitochondrial aspartate aminotransferase linked to immunoglobulin G of the kappa-lambda type: report of a case. Clinica chimica acta; international journal of clinical chemistry. vol 160. issue 3. 1987-01-29. PMID:3098451. |
macromolecular aspartate aminotransferase (l-aspartate: 2-oxoglutarate aminotransferase ec 2.6.1.1, ast) was found in the serum of a patient with benign hypertension. |
1987-01-29 |
2023-08-11 |
human |
| P T Dawes, P D Fowler, R Jackson, M Collins, M F Shadforth, R Stone, D L Scot. Prediction of progressive joint damage in patients with rheumatoid arthritis receiving gold or D-penicillamine therapy. Annals of the rheumatic diseases. vol 45. issue 11. 1987-01-02. PMID:3539037. |
these patients had less severe initial radiological damage, lower levels of serum aspartate transaminase (serum ast) and lactic dehydrogenase (ldh), but higher levels of serum cholesterol. |
1987-01-02 |
2023-08-11 |
Not clear |
| B A Israeli, E Bogi. Biochemical changes in liver, kidney and blood associated with common bile duct ligation. Clinica chimica acta; international journal of clinical chemistry. vol 160. issue 2. 1986-12-29. PMID:3780011. |
in the liver from cbdl rats the activities of aspartate aminotransferase (ast), mg-atpase and alp were elevated, while sdh, ald, malic dehydrogenase (mdh), ldh, malic enzyme (me) and na,k-atpase were lowered. |
1986-12-29 |
2023-08-11 |
rat |
| S A Center, B H Baldwin, H Erb, B C Tennan. Bile acid concentrations in the diagnosis of hepatobiliary disease in the cat. Journal of the American Veterinary Medical Association. vol 189. issue 8. 1986-12-16. PMID:3771358. |
serum values of total bilirubin, alkaline phosphatase (alp), alanine transaminase (alt), and aspartate transaminase (ast) also were measured. |
1986-12-16 |
2023-08-11 |
cat |
| M Panteghini, C Cuccia, M Calarco, P Gei, E Bozzetti, O Visiol. Serum enzymes in acute myocardial infarction after intracoronary thrombolysis. Clinical biochemistry. vol 19. issue 5. 1986-12-09. PMID:3769194. |
serum kinetics of total creatine kinase (ck), ck-mb isoenzyme, aspartate aminotransferase (ast), lactate dehydrogenase (ld) and alpha-hydroxybutyrate dehydrogenase (hbd) activities were studied in twenty patients with acute myocardial infarction randomly assigned to receive either intracoronary urokinase (group a) or conventional (control) therapy (group b). |
1986-12-09 |
2023-08-11 |
Not clear |
| A E Niblock, F Y Leung, A R Henderso. Serum aspartate aminotransferase storage and the effect of pyridoxal phosphate. The Journal of laboratory and clinical medicine. vol 108. issue 5. 1986-12-09. PMID:3772227. |
the storage stability of the catalytic activity of aspartate aminotransferase (ast) remains the subject of conflicting reports. |
1986-12-09 |
2023-08-11 |
human |
| K K Steinberg, L W Freni-Titulaer, T N Rogers, V W Burse, P W Mueller, P A Stehr, D T Miller, G Steel. Effects of polychlorinated biphenyls and lipemia on serum analytes. Journal of toxicology and environmental health. vol 19. issue 3. 1986-11-24. PMID:3021964. |
twelve serum analytes [triglycerides, cholesterol, total and conjugated bilirubin, high-density-lipoprotein cholesterol (hdl-c), alkaline phosphatase (ap), gammaglutamyl transferase (ggt), aspartate aminotransferase (ast), alanine aminotransferase (alt), beta-glucuronidase (beta-glu), alanine aminopeptidase (aap), and 5'-nucleotidase (5'nuc)] were measured to investigate their correlation with exposure to polychlorinated biphenyls (pcbs) and 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (ddt). |
1986-11-24 |
2023-08-11 |
Not clear |
| R M Zinkernagel, E Haenseler, T Leist, A Cerny, H Hengartner, A Althag. T cell-mediated hepatitis in mice infected with lymphocytic choriomeningitis virus. Liver cell destruction by H-2 class I-restricted virus-specific cytotoxic T cells as a physiological correlate of the 51Cr-release assay? The Journal of experimental medicine. vol 164. issue 4. 1986-11-13. PMID:3489805. |
the severity of hepatitis was monitored histologically and by determination of changes in serum levels of the enzymes alanine aminotransferase (alt), aspartate aminotransferase (ast), glutamate dehydrogenase (gldh), and alkaline phosphatase (ap). |
1986-11-13 |
2023-08-11 |
mouse |
| M Gómez-Bautista, F A Rojo-Vázque. Chemotherapy and chemoprophylaxis of hepatic coccidiosis with sulphadimethoxine and pyrimethamine. Research in veterinary science. vol 41. issue 1. 1986-10-30. PMID:2876468. |
the activity in serum of aspartate aminotransferase (ast) and alanine aminotransferase, alkaline phosphatase and gamma-glutamyltranspeptidase were studied as indicators of hepatic lesions. |
1986-10-30 |
2023-08-11 |
Not clear |