| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Masserano, L Gong, H Kulaga, I Baker, R J Wyat. Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system. Molecular pharmacology. vol 50. issue 5. 1996-12-26. PMID:8913362. |
these findings indicate that the oxidative products of dopamine cause neurotoxicity through apoptosis. |
1996-12-26 |
2023-08-12 |
Not clear |
| J M Masserano, L Gong, H Kulaga, I Baker, R J Wyat. Dopamine induces apoptotic cell death of a catecholaminergic cell line derived from the central nervous system. Molecular pharmacology. vol 50. issue 5. 1996-12-26. PMID:8913362. |
apoptosis seems to be produced by dopamine autoxidation, because intracellular peroxides increase after dopamine treatment and cell death can be inhibited by catalase and n-acetylcysteine. |
1996-12-26 |
2023-08-12 |
Not clear |
| D Offen, I Ziv, H Sternin, E Melamed, A Hochma. Prevention of dopamine-induced cell death by thiol antioxidants: possible implications for treatment of Parkinson's disease. Experimental neurology. vol 141. issue 1. 1996-11-12. PMID:8797665. |
we have recently shown that dopamine (da) can trigger apoptosis, an active program of cellular self-destruction, in various neuronal cultures and proposed that inappropriate activation of apoptosis by da and or its oxidation products may initiate nigral cell loss in parkinson's disease (pd). |
1996-11-12 |
2023-08-12 |
Not clear |
| E D Clarkson, W M Zawada, C R Free. GDNF reduces apoptosis in dopaminergic neurons in vitro. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742438. |
gdnf reduced the rate of apoptosis in dopamine neurons from 5% to 2%. |
1996-10-17 |
2023-08-12 |
human |
| Nikitin AYu, W H Le. Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice. Genes & development. vol 10. issue 15. 1996-09-24. PMID:8756345. |
atypical melanotrophs remain competent for dopamine d2 receptor stimulation and undergo s-phase apoptosis in close proximity to nerve terminals. |
1996-09-24 |
2023-08-12 |
mouse |
| E Josefsson, J Bergquist, R Ekman, A Tarkowsk. Catecholamines are synthesized by mouse lymphocytes and regulate function of these cells by induction of apoptosis. Immunology. vol 88. issue 1. 1996-09-12. PMID:8707341. |
incubation of lymphoid cells with l-dopa, dopamine and norepinephrine dose-dependently induced apoptosis which, at least partly, explains the suppressive effects of catecholamines on lymphocyte function. |
1996-09-12 |
2023-08-12 |
mouse |
| D Offen, I Ziv, S Gorodin, A Barzilai, Z Malik, E Melame. Dopamine-induced programmed cell death in mouse thymocytes. Biochimica et biophysica acta. vol 1268. issue 2. 1995-10-10. PMID:7662705. |
exposure of mouse thymocytes to dopamine caused apoptosis (programmed cell death). |
1995-10-10 |
2023-08-12 |
mouse |
| D Offen, I Ziv, S Gorodin, A Barzilai, Z Malik, E Melame. Dopamine-induced programmed cell death in mouse thymocytes. Biochimica et biophysica acta. vol 1268. issue 2. 1995-10-10. PMID:7662705. |
comparison of the potassium (k) and p concentrations showed significant differences between the two major death processes: necrosis (induced by exposure to sodium azide (nan3)) and apoptosis (induced by dopamine). |
1995-10-10 |
2023-08-12 |
mouse |
| I Ziv, E Melamed, N Nardi, D Luria, A Achiron, D Offen, A Barzila. Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons--a possible novel pathogenetic mechanism in Parkinson's disease. Neuroscience letters. vol 170. issue 1. 1994-08-25. PMID:8041491. |
we report that exposure of cultured, postmitotic chick-embryo sympathetic neurons, to physiological concentrations of dopamine (0.1-1 mm) for 24 h initiates a cellular death process characteristic of apoptosis (= programmed-cell-death, pcd). |
1994-08-25 |
2023-08-12 |
chicken |