| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R A Harris, D Snell, H H Loh, E L Wa. Behavioral interactions between naloxone and dopamine agonists. European journal of pharmacology. vol 43. issue 3. 1977-08-12. PMID:872878. |
it is suggested that the rate decreasing effects of low doses of apomorphine and et-495 may be related to presynaptic inhibition of dopamine neurons and that under certain circumstances naloxone may also inhibit dopaminergic activity. |
1977-08-12 |
2023-08-11 |
rat |
| D P Henry, W Aoi, M H Weinberge. The effects of dopamine on renin release in vitro. Endocrinology. vol 101. issue 1. 1977-07-29. PMID:16742. |
further, this direct effect of dopamine on renin release appears to be mediated by an agonistic effect on the juxtaglomerular beta receptor rather than by the presence of a specific dopaminergic receptor for renin release. |
1977-07-29 |
2023-08-11 |
rat |
| R C Smith, C A Tamminga, J Haraszti, G N Pandey, J M Davi. Effects of dopamine agonists in tardive dyskinesia. The American journal of psychiatry. vol 134. issue 7. 1977-07-29. PMID:869053. |
the authors used a combined behavioral and neuroendocrinological strategy to investigate the relevance of abnormalities in the brain dopaminergic systems to the pathophysiology of tardive dyskinesia by assessing the effects of apomorphine, a directly acting dopamine agonist, and d-amphetamine, an indirectly acting dopamine agonist, in patients with tardive dyskinesia. |
1977-07-29 |
2023-08-11 |
human |
| P F Spano, M Trabucchi, G Di Chiar. Localization of nigral dopamine-sensitive adenylate cyclase on neurons originating from the corpus striatum. Science (New York, N.Y.). vol 196. issue 4296. 1977-07-18. PMID:17159. |
the results suggest that dopamine, released from nigral dendrites, may influence dopaminergic activity indirectly by modulating impulses transmitted to the nigrostriatal neurons through the crus cerebri. |
1977-07-18 |
2023-08-11 |
rat |
| H A Nasrallah, E F Donnelly, L B Bigelow, L Rivera-Calimlim, A Rogol, S Potkin, F P Rauscher, R J Wyat. Inhibition of dopamine synthesis in chronic schizophrenia. Clinical ineffectiveness of metyrosine. Archives of general psychiatry. vol 34. issue 6. 1977-07-18. PMID:17374. |
according to the dopamine (da) hypothesis of schizophrenia, there is a functional excess of dopaminergic activity within unspecified areas of the brain in schizophrenic patients. |
1977-07-18 |
2023-08-11 |
Not clear |
| T G Heffner, M J Zigmond, E M Stricke. Effects of dopaminergic agonists and antagonists of feeding in intact and 6-hydroxydopamine-treated rats. The Journal of pharmacology and experimental therapeutics. vol 201. issue 2. 1977-06-30. PMID:859104. |
the ability of dopaminergic agonists and antagonists to inhibit food intake was also observed in rats treated with 6-hhyroxydopamine so as to produce a selective 83% depletion of dopamine. |
1977-06-30 |
2023-08-11 |
rat |
| T G Heffner, M J Zigmond, E M Stricke. Effects of dopaminergic agonists and antagonists of feeding in intact and 6-hydroxydopamine-treated rats. The Journal of pharmacology and experimental therapeutics. vol 201. issue 2. 1977-06-30. PMID:859104. |
we conclude that both increases and decreases in central dopaminergic activity can reduce feeding and propose that some intermediate rate of dopamine release provides an optimal level of neuronal activity for feeding by the hungry animal. |
1977-06-30 |
2023-08-11 |
rat |
| T Ranta, P Männistö, J Tuomist. Evidence for dopaminergic control of thyrotrophin secretion in the rat. The Journal of endocrinology. vol 72. issue 3. 1977-06-22. PMID:404378. |
these results suggest that there are no dopaminergic receptors on the pituitary thyrotrophs, but that dopamine might be an inhibitory transmitter in the brain involved in the regulation of tsh secretion in the rat. |
1977-06-22 |
2023-08-11 |
rat |
| R Kuczenski, D Schmidt, N Leit. Amphetamine-haloperidol interactions in rat striatum: failure to correlate behavioral effects with dopaminergic and cholinergic dynamics. Brain research. vol 126. issue 1. 1977-06-22. PMID:558038. |
in the present study, we have measured the behavioral effects of amp and hal, and their effects on striatal dopaminergic function, using both an index of pre-synaptic activity (synaptosomal dopamine (da) synthesis) and a parameter which we suggest will reflect post-synaptic dopaminergic function (sodium-dependent, high affinity choline uptake). |
1977-06-22 |
2023-08-11 |
rat |
| J A Clemens, F C Tinsley, R W Fulle. Evidence for a dopaminergic component in the series of neural events that lead to the pro-oestrous surge of LH. Acta endocrinologica. vol 85. issue 1. 1977-06-22. PMID:577075. |
the possible participation of dopamine in the neural events that lead to the pro-oestrous surge of luteinizing hormone (lh) was investigated utilizing a dopaminergic ergoline derivative (lergotrile mesylate). |
1977-06-22 |
2023-08-11 |
rat |
| O Kuchel, J L Cuche, N T Buu, G P Guthrie, T Unger, W Nowaczynski, R Boucher, J Genes. Catecholamine excretion in "idiopathic" edema: decreased dopamine excretion, a pathogenic factor? The Journal of clinical endocrinology and metabolism. vol 44. issue 4. 1977-05-27. PMID:849977. |
these results suggest that a decrease in urinary dopamine, a catecholamine recently recognized to have natriuretic action, possibly reflects a suppression of the renal dopaminergic system and may contribute to the excessive sodium retention in idiopathic edema either directly or indirectly through the renin-aldosterone system. |
1977-05-27 |
2023-08-11 |
human |
| M F Giorguieff, M L Le Floc'h, J Glowinski, M J Besso. Involvement of cholinergic presynaptic receptors of nicotinic and muscarinic types in the control of the spontaneous release of dopamine from striatal dopaminergic terminals in the rat. The Journal of pharmacology and experimental therapeutics. vol 200. issue 3. 1977-05-27. PMID:850127. |
involvement of cholinergic presynaptic receptors of nicotinic and muscarinic types in the control of the spontaneous release of dopamine from striatal dopaminergic terminals in the rat. |
1977-05-27 |
2023-08-11 |
rat |
| J Gerlac. Relationship between tardive dyskinesia, L-Dopa-induced hyperkinesia and parkinsonism. Psychopharmacology. vol 51. issue 3. 1977-05-20. PMID:403541. |
it is concluded that the irreversible neurotoxic effect of neuroleptic drugs may be associated with age-related changes in the oral somatotopic region of the basal ganglia (to be given consideration in any future search for the pathogenetic process underlying irreversible tardive dyskinesia), and that the pathophysiology of involuntary hyperkinesia in neuroleptic-treated psychiatric patients and in l-dopatreated parkinson patients may consist of a primary dopamine deficiency (pharmacological or structural), and a secondary relative hyperactivity in the dopaminergic system ("dopaminergic hypersensitivity") possibly corresponding to hypoactivity in the cholinergic system. |
1977-05-20 |
2023-08-11 |
Not clear |
| J Dankova, R Boucher, L J Poirie. Effects of 1694 and other dopaminergic agents on circling behavior. European journal of pharmacology. vol 42. issue 2. 1977-05-20. PMID:557412. |
although this experimental model is useful to determine the degree of dopaminergic activity of various chemical agents it does not duplicate the motor disorders encountered in parkinsonism which are associated with a decreased concentration of dopamine. |
1977-05-20 |
2023-08-11 |
rat |
| H Y Meltzer, V S Fang, M Simonovich, S M Pau. Effect of metabolites of chlorpromazine on plasma prolactin levels in male rats. European journal of pharmacology. vol 41. issue 4. 1977-05-20. PMID:844484. |
since prolactin secretion is under vigorous dopaminergic inhibition, neuroleptic drugs can, because of their capacity to block dopamine receptors, produce large increases in plasma prolactin levels in man and laboratory animals. |
1977-05-20 |
2023-08-11 |
rat |
| M J Bastie, N Vaysse, B Brenac, J P Pascal, A Ribe. Effects of catecholamines and their inhibitors on the isolated canine pancreas. II. Dopamine. Gastroenterology. vol 72. issue 4 Pt 1. 1977-04-28. PMID:838228. |
dopaminergic agonists (dopamine, 2, 10, 50, and 250 mug; apomorphine, 1 mg; noradrenaline, 2, 20, and 200 mug), and inhibitors (haloperidol, 5 mg; pentamethonium, 500 mg; phenoxybenzamine, 15 mg, and atropine sulfate, 10 mg), were tested on isolated perfused canine pancreas; under basal conditions and under stimulation by a background of secretin (0.1, 0.5, and 10.0 clinical unit per hr), or of caerulein (1200 ng per hr). |
1977-04-28 |
2023-08-11 |
Not clear |
| T Mitsuma, Y Hirooka, N Nihe. [The effect of various amines on TRH contents in rat brain (author's transl)]. Nihon Naibunpi Gakkai zasshi. vol 52. issue 8. 1977-04-25. PMID:138603. |
the above data suggested the trh contents in rat brain were increased with increase of dopamine level in rat brain and decreased with increase of serotonine level or decrease of noradrenaline level in rat brain and inhibitory effect of t4 or t3 on trh release might be mediated through dopaminergic and serotonergic mechanism. |
1977-04-25 |
2023-08-11 |
rat |
| J Costentin, H Marçais, P Protais, M Baudry, M P Martres, J C Schwart. [Facilitation of a stereotyped motor behavior (climbing behavior) by previous stimulation of dopaminergic receptors: hyposensitivity of autoreceptors?]. Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles. vol 284. issue 2. 1977-04-25. PMID:402241. |
the hypothesis is put forward that "behavioural facilitation" results from the hyposensitivity of a class of dopamine receptors, possibly autoreceptors, mediating an impaired activity of dopaminergic neurons and, consequently, inhibitory behavioural effects. |
1977-04-25 |
2023-08-11 |
mouse |
| F Camanni, F Massara, L Belforte, A Rosatello, G M Molinatt. Effect of dopamine on plasma growth hormone and prolactin levels in normal and acromegalic subjects. The Journal of clinical endocrinology and metabolism. vol 44. issue 3. 1977-04-25. PMID:838847. |
in contrast with other dopaminergic drugs (l-dopa, apomorphine or bromocriptine) a 280 mug/min dose of dopamine infused for 120 min failed to induce an increase in plasma gh in 9 normal subjects. |
1977-04-25 |
2023-08-11 |
human |
| F Camanni, F Massara, L Belforte, A Rosatello, G M Molinatt. Effect of dopamine on plasma growth hormone and prolactin levels in normal and acromegalic subjects. The Journal of clinical endocrinology and metabolism. vol 44. issue 3. 1977-04-25. PMID:838847. |
since dopamine does not readily cross the blood-brain barrier, these results suggest that the stimulating effect of dopaminergic drugs on gh secretion in the normal subject is exerted via the cns, whereas in acromegaly there is a direct action on structures lying outside the blood-brain barrier, probably in the hypophysis. |
1977-04-25 |
2023-08-11 |
human |