| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Bagdy, K Szemeredi, J L Hill, D L Murph. The serotonin agonist, M-chlorophenylpiperazine, markedly increases levels of plasma catecholamines in the conscious rat. Neuropharmacology. vol 27. issue 10. 1989-05-02. PMID:3237317. |
these findings are consistent with other studies reporting that stimulation of serotonergic receptors increases centrally-mediated sympathetic outflow and leads to increases in the concentrations of norepinephrine, epinephrine and dopamine in plasma. |
1989-05-02 |
2023-08-11 |
rat |
| M Johnson, G R Hanson, J W Gib. Effects of dopaminergic and serotonergic receptor blockade on neurochemical changes induced by acute administration of methamphetamine and 3,4-methylenedioxymethamphetamine. Neuropharmacology. vol 27. issue 11. 1989-02-09. PMID:3144655. |
as dopamine (da) causes neurochemical changes in the central serotonergic system after an acute injection of methamphetamine, the present study examined the possibility that this response is mediated through dopaminergic receptors. |
1989-02-09 |
2023-08-11 |
Not clear |
| M Mori, Y Hoshino, H Obara, S Iwa. Maturation-related changes in dopamine-induced relaxation of isolated rabbit pulmonary artery. Pediatric research. vol 24. issue 2. 1988-11-29. PMID:3186329. |
dopamine receptor-mediated relaxant effects can only be observed when vessels are precontracted with prostaglandin f2 alpha and in the presence of alpha 1, alpha 2, beta, and serotonergic blockade. |
1988-11-29 |
2023-08-11 |
rabbit |
| D M Stone, M Johnson, G R Hanson, J W Gib. Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine. The Journal of pharmacology and experimental therapeutics. vol 247. issue 1. 1988-11-18. PMID:2902215. |
role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine. |
1988-11-18 |
2023-08-11 |
rat |
| D M Stone, M Johnson, G R Hanson, J W Gib. Role of endogenous dopamine in the central serotonergic deficits induced by 3,4-methylenedioxymethamphetamine. The Journal of pharmacology and experimental therapeutics. vol 247. issue 1. 1988-11-18. PMID:2902215. |
because the serotonergic toxicity associated with the mdma analog methamphetamine has been linked previously to endogenous dopamine and because mdma, like methamphetamine, elicits pronounced dopamine release in vitro, we have examined the role of endogenous dopamine in both the immediate (3 hr) and longer-term (3 days) central serotonergic deficits induced by systemic mdma administration to rats. |
1988-11-18 |
2023-08-11 |
rat |
| E L Noisin, W E Thoma. Ontogeny of dopaminergic function in the rat midbrain tegmentum, corpus striatum and frontal cortex. Brain research. vol 469. issue 1-2. 1988-09-15. PMID:3401800. |
results from competitive inhibition experiments using various serotonergic and dopaminergic antagonists suggested that at all ages dopamine d2-receptors were responsible for spiperone binding in corpus striatum and midbrain tegmentum. |
1988-09-15 |
2023-08-11 |
rat |
| L A Bero, S N Lurie, C M Kuh. Early ontogeny of kappa-opioid receptor regulation of prolactin secretion in the rat. Brain research. vol 465. issue 1-2. 1988-04-19. PMID:2894234. |
kappa-receptors appear to regulate prl secretion by directly inhibiting the activity of tuberoinfundibular dopamine neurons, while mu-receptors might regulate the tonic dopaminergic inhibition of prl through a serotonergic pathway. |
1988-04-19 |
2023-08-11 |
rat |
| W J Brooks, M F Jarvis, G C Wagne. Attenuation of MPTP-induced dopaminergic neurotoxicity by a serotonin uptake blocker. Journal of neural transmission. vol 71. issue 2. 1988-04-18. PMID:3258013. |
in keeping with its demonstrated ability to inhibit uptake into serotonergic neurons and serotonin uptake into astrocytes, fluoxetine pretreatment resulted in a significant attenuation of mptp-induced depletions of striatal dopamine and serotonin concentration. |
1988-04-18 |
2023-08-11 |
Not clear |
| J G Cannon, P Mohan, J Bojarski, J P Long, R K Bhatnagar, P A Leonard, J R Flynn, T K Chatterje. (R)-(-)-10-methyl-11-hydroxyaporphine: a highly selective serotonergic agonist. Journal of medicinal chemistry. vol 31. issue 2. 1988-03-16. PMID:3339604. |
surprisingly, the target compound elicited no responses in any assays for effects at dopamine receptors, but rather it displayed pharmacological properties consistent with its being a serotonergic agonist with a high degree of selectivity for 5-ht1a receptors similar to the serotonergic agonist 8-hydroxy-2-(di-n-propylamino)tetralin. |
1988-03-16 |
2023-08-11 |
Not clear |
| T P Jerussi, J F Capacchione, M J Benveng. Reversal of opioid-induced muscular rigidity in rats: evidence for alpha-2 adrenergic involvement. Pharmacology, biochemistry, and behavior. vol 28. issue 2. 1988-01-13. PMID:2891145. |
on the other hand, serotonergic drugs and dopamine agonists were not. |
1988-01-13 |
2023-08-11 |
rat |
| A Romaniuk, M Filipczak, J Frycza. The influence of injection of 5,6-dihydroxytryptamine to the dorsal raphe nucleus on carbachol-induced defensive behavior and regional brain amine content in the cat. Polish journal of pharmacology and pharmacy. vol 39. issue 1. 1987-11-25. PMID:2444950. |
the 5,6-dihydroxytryptamine-induced lesions of serotonergic neurons in the dorsal raphe nucleus of the cat resulted in an increase in the carbachol-induced growling response, a decrease in the concentrations of noradrenaline, serotonin and 5-hydroxyindoleacetic acid in the hypothalamus, midbrain and amygdala, and an increase in the hypothalamic dopamine level. |
1987-11-25 |
2023-08-11 |
cat |
| M G De Simoni, G Dal Toso, F Fodritto, A Sokola, S Alger. Modulation of striatal dopamine metabolism by the activity of dorsal raphe serotonergic afferences. Brain research. vol 411. issue 1. 1987-08-28. PMID:2440514. |
modulation of striatal dopamine metabolism by the activity of dorsal raphe serotonergic afferences. |
1987-08-28 |
2023-08-11 |
rat |
| I Murai, N Ben-Jonatha. Posterior pituitary lobectomy abolishes the suckling-induced rise in prolactin (PRL): evidence for a PRL-releasing factor in the posterior pituitary. Endocrinology. vol 121. issue 1. 1987-07-27. PMID:3496207. |
the second experiment tested the functional integrity of the hypothalamic dopamine (da) and serotonergic systems after lobex and the ability of lobex-lactating rats to respond to prl-releasing stimuli other than suckling. |
1987-07-27 |
2023-08-11 |
rat |
| G E Nilsson, O Tottmar, G Wahlströ. Effects of aldehyde dehydrogenase inhibitors on hexobarbital sensitivity and neuroamine metabolism in rat brain. Brain research. vol 409. issue 2. 1987-07-16. PMID:2438009. |
no alteration of the dopamine level in brain was found in rats given disulfiram, and in both disulfiram- and coprine-treated rats, similar changes in the serotonergic system were found. |
1987-07-16 |
2023-08-11 |
rat |
| E H Lee, F B Wang, Y P Tang, M A Geye. Gabaergic interneurons in the dorsal raphe mediate the effects of apomorphine on serotonergic system. Brain research bulletin. vol 18. issue 3. 1987-07-16. PMID:2438015. |
we have previously demonstrated that the serotonergic actions of apo were secondary to dopamine (da) autoreceptor stimulation in the substantia nigra. |
1987-07-16 |
2023-08-11 |
Not clear |
| L A Matsuda, C J Schmidt, J W Gibb, G R Hanso. Ascorbic acid-deficient condition alters central effects of methamphetamine. Brain research. vol 400. issue 1. 1987-03-30. PMID:2434185. |
various lines of evidence indicate that dopamine is an essential mediator of meth-induced effects in both serotonergic and substance p systems in the brain areas examined; however, results from the present study indicate that, along with dopamine, ascorbic acid also plays a role in mediating the effects of meth in the central nervous system. |
1987-03-30 |
2023-08-11 |
Not clear |
| C H Vanderwolf, D J Stewar. Joint cholinergic-serotonergic control of neocortical and hippocampal electrical activity in relation to behavior: effects of scopolamine, ditran, trifluoperazine and amphetamine. Physiology & behavior. vol 38. issue 1. 1987-01-14. PMID:3786502. |
in addition, new evidence is presented which indicates that neuroleptic drugs reduce activity in the atropine-resistant (presumably serotonergic) inputs to the hippocampus and neocortex by an indirect action involving dopamine receptors. |
1987-01-14 |
2023-08-11 |
rat |
| H Agren, I N Mefford, M V Rudorfer, M Linnoila, W Z Potte. Interacting neurotransmitter systems. A non-experimental approach to the 5HIAA-HVA correlation in human CSF. Journal of psychiatric research. vol 20. issue 3. 1986-12-04. PMID:2430098. |
the concept of a serotonergic regulation of dopamine turnover was tested on brain punch analyses of serotonin and dopamine and their metabolites in two sets of dogs in a large number of brain areas. |
1986-12-04 |
2023-08-11 |
human |
| K Yamaguchi, T Nabeshima, T Kameyam. Potentiation of phencyclidine-induced dopamine-dependent behaviors in rats after pretreatments with serotonin-depletors. Journal of pharmacobio-dynamics. vol 9. issue 5. 1986-11-10. PMID:2945001. |
this study was designed to assess whether phencyclidine (pcp) produces dopamine (da)-dependent behaviors such as licking, gnawing and biting (which are not observed in normal rats) in rats after pretreatments with a tryptophan hydroxylase inhibitor, p-chlorophenylalanine (pcpa) and specific serotonergic neuronal toxin, p-chloroamphetamine (pca). |
1986-11-10 |
2023-08-11 |
rat |
| P K Sonsalla, J W Gibb, G R Hanso. Roles of D1 and D2 dopamine receptor subtypes in mediating the methamphetamine-induced changes in monoamine systems. The Journal of pharmacology and experimental therapeutics. vol 238. issue 3. 1986-10-23. PMID:2943891. |
previous studies have demonstrated that the effects of methamphetamine (meth) on dopaminergic and serotonergic systems are likely related to meth-induced increases in dopamine release. |
1986-10-23 |
2023-08-11 |
Not clear |