| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C G Clough, K J Bergmann, M D Yah. Cholinergic and dopaminergic mechanisms in Parkinson's disease after long-term L-DOPA administration. Advances in neurology. vol 40. 1984-03-07. PMID:6695589. |
these findings are interpreted as indicating that the dopaminergic receptors are available for stimulation during the off phase but are not receiving sufficient neurotransmitter, that is, dopamine, to stimulate their activity. |
1984-03-07 |
2023-08-12 |
Not clear |
| M F Lokhandwala, M L Steenber. Selective activation by LY-141865 and apomorphine of presynaptic dopamine receptors in the rat kidney and influence of stimulation parameters in the action of dopamine. The Journal of pharmacology and experimental therapeutics. vol 228. issue 1. 1984-02-29. PMID:6694099. |
these results suggest that dopamine-induced inhibition of norepinephrine release depends on the conditions of stimulation, i.e., during lower frequencies of sympathetic nerve stimulation, inhibition occurs by simultaneous activation of both presynaptic dopamine receptors as well as alpha adrenoceptors, whereas only presynaptic dopamine receptors are responsible for the inhibition of neurotransmitter release caused by dopamine at the higher frequency of nerve stimulation. |
1984-02-29 |
2023-08-12 |
rat |
| G D Ellison, M S Eiso. Continuous amphetamine intoxication: an animal model of the acute psychotic episode. Psychological medicine. vol 13. issue 4. 1984-02-28. PMID:6320247. |
at about the same time there are distinctive and partially irreversible alterations in dopaminergic innervations of the caudate nucleus, but not in mesolimbic dopamine innervation of the nucleus accumbens or in several other neurotransmitter systems. |
1984-02-28 |
2023-08-12 |
rat |
| R J Jensen, N W Da. Towards an understanding of the role of dopamine in the mammalian retina. Vision research. vol 23. issue 11. 1984-02-24. PMID:6659376. |
the role of the neurotransmitter dopamine in visual processing in the mammalian retina is not known. |
1984-02-24 |
2023-08-12 |
rabbit |
| J A Severso. Neurotransmitter receptors and aging. Journal of the American Geriatrics Society. vol 32. issue 1. 1984-02-15. PMID:6317731. |
the role of receptors in the central nervous system and effects of aging on the four neurotransmitter receptors most often studied in the context of aging--beta-adrenergic, cholinergic, benzodiazepine, and dopamine--are discussed. |
1984-02-15 |
2023-08-12 |
Not clear |
| P M Iuvone, A L Rauc. Alpha 2-adrenergic receptors influence tyrosine hydroxylase activity in retinal dopamine neurons. Life sciences. vol 33. issue 24. 1984-01-26. PMID:6139733. |
dopamine (da) is a putative neurotransmitter in a population of interneurons in the mammalian retina that are activated by photic stimulation. |
1984-01-26 |
2023-08-12 |
rat |
| C W Kamp, W W Morga. Effects of excitatory amino acids on dopamine synthesis in the rat retina. European journal of pharmacology. vol 92. issue 1-2. 1983-12-17. PMID:6138258. |
these results are the first to show that the quiescent dopamine neurons of the dark-adapted rat retina can be activated by an excitatory amino acid analogue of the putative endogenous neurotransmitter, glutamate. |
1983-12-17 |
2023-08-12 |
rat |
| L A Kamal, S Arbilla, A M Galzin, S Z Lange. Amphetamine inhibits the electrically evoked release of [3H]dopamine from slices of the rabbit caudate. The Journal of pharmacology and experimental therapeutics. vol 227. issue 2. 1983-12-17. PMID:6631724. |
the dopamine receptor antagonists, haloperidol and sulpiride, were not able to antagonize the inhibition by amphetamine of the electrically evoked release of [3h] dopamine at concentrations which effectively blocked apomorphine-induced inhibition of stimulation-evoked release of the labeled neurotransmitter. |
1983-12-17 |
2023-08-12 |
rabbit |
| S C Silver, J A Patterson, P G Mobb. Biogenic amines in cephalopod retina. Brain research. vol 273. issue 2. 1983-11-23. PMID:6137266. |
biochemical and ultrastructural studies by previous workers have suggested dopamine as a candidate neurotransmitter for the centrifugal neurons present in the cephalopod retina. |
1983-11-23 |
2023-08-12 |
Not clear |
| F Ponzio, G Achilli, C Perego, G Rinaldi, S Alger. Does acute L-DOPA increase active release of dopamine from dopaminergic neurons? Brain research. vol 273. issue 1. 1983-11-23. PMID:6616231. |
l-dopa is believed to be decarboxylated by the residual striatal dopaminergic presynaptic terminals with formation of the putative neurotransmitter dopamine (da) and with increased availability of da at post-synaptic receptors. |
1983-11-23 |
2023-08-12 |
Not clear |
| W Kolasiewicz, A Harasiewicz, M Melzacka, S Wolfart. Alterations in apomorphine concentration in spinal cord and brain follow the time course of catalepsies induced by different treatments. Experimental neurology. vol 81. issue 1. 1983-08-26. PMID:6861947. |
because evidence for the neurotransmitter role of dopamine in the gray matter of the spinal cord is accumulating, a question arises of whether or not spinal dopamine receptors are also involved in the effects of dopaminomimetics which are believed to induce beneficial effects in parkinson's disease through an action thought to be mediated mainly by striatal dopamine receptors. |
1983-08-26 |
2023-08-12 |
Not clear |
| C J Pycock, L F Smit. Interactions of dopamine and the release of [3H]-taurine and [3H]-glycine from the isolated retina of the rat. British journal of pharmacology. vol 78. issue 2. 1983-05-27. PMID:6187404. |
this delayed release of [(3)h]-taurine was unaffected if dopamine was applied to the superfusate at the same time as the potassium, but it was significantly reduced if dopamine (0.8 and 4 mm) was applied after the depolarizing stimulus had been removed and during the actual amino acid release phase.7 the inhibition of k(+)-stimulated (25 mm) delayed release of [(3)h]-taurine by applying dopamine (0.8 mm) after the depolarizing stimulus was blocked by 10 mum (+)-butaclamol but not by 10 mum (-)-butaclamol.8 the results are discussed with respect to the possible neurotransmitter role for dopamine within the rat retina, and its possible interaction with glycine and taurine. |
1983-05-27 |
2023-08-12 |
rat |
| J Price, A W Mudg. A subpopulation of rat dorsal root ganglion neurones is catecholaminergic. Nature. vol 301. issue 5897. 1983-03-17. PMID:6130474. |
we have used here antisera against tyrosine hydroxylase (th; ec 1.14.16.2) and dopamine-beta-hydroxylase (dbh; ec 1.14.17.1), two enzymes specific to catecholaminergic cells, to show that a subpopulation of rat drg neurones is catecholaminergic and that the neurotransmitter they make is probably dopamine. |
1983-03-17 |
2023-08-12 |
rat |
| G Bamme. Pharmacological investigations of neurotransmitter involvement in passive avoidance responding: a review and some new results. Neuroscience and biobehavioral reviews. vol 6. issue 3. 1983-02-14. PMID:6129605. |
the roles of acetylcholine (ach), noradrenaline (na), dopamine (da) and serotonin (5-ht) in passive avoidance responding are examined by reviewing previous studies of the effects on this task of drugs which alter the functioning of these neurotransmitter systems and also by presenting the results of a new study. |
1983-02-14 |
2023-08-12 |
Not clear |
| R Albibi, R W McCallu. Metoclopramide: pharmacology and clinical application. Annals of internal medicine. vol 98. issue 1. 1983-01-27. PMID:6336644. |
metoclopramide's gastrointestinal smooth muscle stimulatory effects are related to its ability to antagonize the inhibitory neurotransmitter, dopamine; to augment acetylcholine release and sensitize the muscarinic receptors of the gastrointestinal smooth muscle; and to coordinate gastric-pyloric-small intestinal motor function. |
1983-01-27 |
2023-08-12 |
Not clear |
| S C Fung, Y C Kong, D M La. Prenatal development of gabaergic, glycinergic, and dopaminergic neurons in the rabbit retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 2. issue 11. 1983-01-07. PMID:6292378. |
the main findings from our studies on the emergence and maturation of neurotransmitter systems in the rabbit retina are that, during normal development: (1) the commitments for certain neurons to become gabaergic, glycinergic, or dopaminergic are made prenatally; the maturation of these neurons, however, occurs postnatally; (2) specific accumulations of exogenously supplied transmitters by presumed retinal neurons were first observed autoradiographically around embryonic day 22 (e22) for gamma-aminobutyric acid (gaba), e25 for glycine, and e27 for dopamine, suggesting that putative gabaergic, glycinergic, and dopaminergic neurons are determined phenotypically at least by these days; (3) based upon the three transmitter-specific properties--uptake, synthesis, and release--the uptake property is generally the first to emerge, while the appearance of the other properties follows a precise and distinct temporal pattern for each of the transmitters studied; (4) for gabaergic and glycinergic systems, the emergence of k+-stimulated, ca2+-dependent release mechanisms occurs many days after the first appearance of the uptake properties; in contrast, the mechanisms for dopamine uptake and release emerge at about the same time; and (5) by our criteria, putative gabaergic and glycinergic amacrine cells are mature between postnatal day 10 (p10) and p12, around the time when the eyes first open and direction-selective ganglion cells can first be recorded; however, the dopaminergic neurons probably are not mature until about p24. |
1983-01-07 |
2023-08-12 |
rabbit |
| R B Murphy, D I Schuste. Modulation of [3H]-dopamine binding by cholecystokinin octapeptide (CCK-8). Peptides. vol 3. issue 3. 1982-12-02. PMID:6289286. |
cholecystokinin-octapeptide (cck-8) is a putative neurotransmitter which has been demonstrated previously to occur in midbrain dopamine neurones. |
1982-12-02 |
2023-08-12 |
rat |
| W W Anderson, D L Barke. Synaptic mechanisms that generate network oscillations in the absence of discrete postsynaptic potentials. The Journal of experimental zoology. vol 216. issue 1. 1981-12-15. PMID:7288387. |
stimulation of the input nerve, or bath application of the input neurotransmitter dopamine, produced similar vigorous bursting in many pyloric neurons. |
1981-12-15 |
2023-08-12 |
lobster |
| K Maeda, L A Frohma. Neurotensin release by rat hypothalamic fragments in vitro. Brain research. vol 210. issue 1-2. 1981-07-23. PMID:6261874. |
the results indicate that neurotensin is released by the hypothalamus in vitro; its release is stimulated by membrane depolarization in a ca2+-dependent manner and may involve an adenylate cyclase mechanism; and dopamine appears to serve as a stimulatory neurotransmitter for neurotensin-containing neurons. |
1981-07-23 |
2023-08-12 |
rat |
| S C Bondy, H A Tilson, A K Agrawa. Neurotransmitter receptors in brain regions of acrylamide- treated rats. II: Effects of extended exposure to acrylamide. Pharmacology, biochemistry, and behavior. vol 14. issue 4. 1981-07-20. PMID:6262843. |
at the two lower doses (5 and 10 mg/kg, total dose 50 and 100 mg/kg) effects on neurotransmitter receptor sites appeared confined to the striatum where both the dopamine and muscarinic acetylcholine receptors exhibited enhanced binding twenty four hours after the last acrylamide dose. |
1981-07-20 |
2023-08-12 |
rat |