| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marina Bellot, Fernando Soria, Raul López-Arnau, Cristian Gómez-Canela, Carlos Barat. Daphnia magna an emerging environmental model of neuro and cardiotoxicity of illicit drugs. Environmental pollution (Barking, Essex : 1987). 2024-01-16. PMID:38228265. |
observed effects on neurotransmitters and related metabolites were in concern with reported responses in mammalian and other vertebrate models: cocaine and mdma enhanced dopamine and serotonin levels, respectively, methamphetamine and mdma decreased dopamine and octopamine, and all but mdma decreased 3 mt levels. |
2024-01-16 |
2024-01-19 |
Not clear |
| Lorissa Lamoureux, Joel A Beverley, Michela Marinelli, Heinz Steine. Fluoxetine potentiates methylphenidate-induced behavioral responses: Enhanced locomotion or stereotypies and facilitated acquisition of cocaine self-administration. Addiction neuroscience. vol 9. 2024-01-15. PMID:38222942. |
mp is a dopamine reuptake inhibitor, but does not affect serotonin. |
2024-01-15 |
2024-01-17 |
rat |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
psilocybin and ketamine increased the release of dopamine (da) and serotonin (5-ht) in the nucleus accumbens of naive rats as demonstrated using microdialysis. |
2024-01-11 |
2024-01-13 |
rat |
| S Birendra Kumar, Aishwarya Girish, Samruddhi Sutar, Suheeth Amberi Premanand, Vrinda Garg, Arvind Kumar Yadav, Rohit Shukla, T P Krishna Murthy, Tiratha Raj Sing. A computational study on structural and functional consequences of nsSNPs in human dopa decarboxylase. Journal of biomolecular structure & dynamics. 2024-01-09. PMID:38193892. |
the dopa decarboxylase (ddc) gene plays an important role in the synthesis of biogenic amines such as dopamine, serotonin, and histamine. |
2024-01-09 |
2024-01-10 |
human |
| Yunjiang Yu, Shihui Tan, Hongzhi Guo, Xin Hua, Haibo Chen, Yue Yang, Dongli Xie, Chuan Yi, Haibo Ling, Mingdeng Xian. Chronic neurotoxicity of Tetrabromobisphenol A: Induction of oxidative stress and damage to neurons in Caenorhabditis elegans. Chemosphere. 2024-01-07. PMID:38185427. |
furthermore, 100 μg/l tcbpa exposure caused a reduction in dopamine and serotonin levels, and damage in dopaminergic and serotoninergic neurons, which was further confirmed by the downregulated expression of related genes (e.g., dop-1, dop-3, cat-1, and mod-1). |
2024-01-07 |
2024-01-10 |
caenorhabditis_elegans |
| Lauren R Fitzgerald, Brenda M Gannon, Donna Walther, Antonio Landavazo, Takato Hiranita, Bruce E Blough, Michael H Baumann, William E Fantegross. Structure-activity relationships for locomotor stimulant effects and monoamine transporter interactions of substituted amphetamines and cathinones. Neuropharmacology. 2023-12-28. PMID:38154512. |
automated photobeam analysis was used to evaluate effects of drugs on ambulatory activity in mice, whereas in vitro assays were used to determine activities at transporters for dopamine (dat), norepinephrine (net), and 5-ht (sert) in rat brain synaptosomes. |
2023-12-28 |
2023-12-31 |
mouse |
| Khaled G Abdel-Wahhab, Rehab S Sayed, Doaa G El-Sahra, Laila K Hassan, Ghada M Elqattan, Fathia A Manna. Echinacea purpurea extract intervention for counteracting neurochemical and behavioral changes induced by bifenthrin. Metabolic brain disease. 2023-12-27. PMID:38150137. |
also, bif induced a significant increase caspas-3, tumor necrosis factor alpha (tnf), and interleukin-1beta (il-1ß) in both areas; dopamine and serotonin levels, and ach-ase activity were markedly decreased in both areas. |
2023-12-27 |
2023-12-29 |
rat |
| Ida Cursio, Sabrina Siliquini, Claudia Carducci, Giovanni Bisello, Mario Mastrangelo, Vincenzo Leuzzi, Mariarita Bertoldi, Carla Marin. Case report: Childhood epilepsy and borderline intellectual functioning hiding an AADC deficiency disorder associated with compound heterozygous Frontiers in neurology. vol 14. 2023-12-20. PMID:38116105. |
case report: childhood epilepsy and borderline intellectual functioning hiding an aadc deficiency disorder associated with compound heterozygous aromatic l-amino acid decarboxylase (aadc) deficiency is a rare autosomal recessive neurometabolic disorder leading to severe combined serotonin, dopamine, norepinephrine, and epinephrine deficiency. |
2023-12-20 |
2023-12-23 |
Not clear |
| Heba-Tallah Abd Elrahim Abd Elkader, Marium Marzoq Hussein, Nema A Mohammed, Heba M Abdo. The protective role of L-carnitine on oxidative stress, neurotransmitter perturbations, astrogliosis, and apoptosis induced by thiamethoxam in the brains of male rats. Naunyn-Schmiedeberg's archives of pharmacology. 2023-12-15. PMID:38099937. |
our results revealed marked serum lipid profile and electrolyte changes, declines in brain antioxidants and neurotransmitters (acetylcholine, dopamine, and serotonin levels) with elevations in thiobarbituric acid reactive substances and proinflammatory cytokine levels, as well as acetylcholinesterase and monoamine oxidase brain activity in tmx-treated rats. |
2023-12-15 |
2023-12-17 |
rat |
| Eugenia Annunzi, Loreta Cannito, Fabio Bellia, Francesca Mercante, Matteo Vismara, Beatrice Benatti, Alberto Di Domenico, Riccardo Palumbo, Walter Adriani, Bernardo Dell'Osso, Claudio D'Addari. Mild internet use is associated with epigenetic alterations of key neurotransmission genes in salivary DNA of young university students. Scientific reports. vol 13. issue 1. 2023-12-13. PMID:38092954. |
aim of this study was to investigate epigenetic and genetic regulation of oxytocin receptor (oxtr), dopamine transporter (dat1) and serotonin transporter (sert) genes using dna obtained from saliva samples of young university students: the internet addiction test (iat) was administered to evaluate the potential existence and intensity of ia. |
2023-12-13 |
2023-12-17 |
human |
| Polona Rus Prelog, Anja Kokalj Palandaci. Hypersexuality during treatment with cariprazine in a patient with schizophrenia? A case report. BMC psychiatry. vol 23. issue 1. 2023-12-11. PMID:38082232. |
it functions as a partial agonist with high affinity for dopamine d2 and d3 and serotonin 5-ht1a receptors, an antagonist for 5-ht2a (moderate affinity) and 5-ht2b (high affinity) receptors. |
2023-12-11 |
2023-12-17 |
Not clear |
| Cruz Reyes-Vasquez, Zachary Jones, Bin Tang, Nachum Dafn. Dopamine, Norepinephrine and Serotonin Participate Differently in Methylphenidate Action in Concomitant Behavioral and Ventral Tegmental Area, Locus Coeruleus and Dorsal Raphe Neuronal Study in Young Rats. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38068951. |
dopamine, norepinephrine and serotonin participate differently in methylphenidate action in concomitant behavioral and ventral tegmental area, locus coeruleus and dorsal raphe neuronal study in young rats. |
2023-12-09 |
2023-12-17 |
rat |
| Juana Monroy, Omar D Cortés, Roberto Domínguez, María Eugenia Mendoza-Garrido, Eloir Gallegos, Mario Cárdenas, Andrés Aragón, María E Ayal. The differential sensitivity of the hypothalamic-hypophysial-ovarian axis to 5-hydroxytryptophan alters the secretion of estradiol. Experimental physiology. 2023-12-08. PMID:38064347. |
micro-injection of 5-htp into the median raphe nucleus increased the concentrations of 5-ht in the anterior hypothalamus and dopamine in the medial hypothalamus after 120 min. |
2023-12-08 |
2023-12-17 |
rat |
| Sarita Pyatha, Haesoo Kim, Daeun Lee, Kisok Ki. Co-exposure to lead, mercury, and cadmium induces neurobehavioral impairments in mice by interfering with dopaminergic and serotonergic neurotransmission in the striatum. Frontiers in public health. vol 11. 2023-12-01. PMID:38026429. |
furthermore, compared to the control group, the metal mixture exposure group showed a significantly lower expression level of tyrosine hydroxylase (th) and significantly higher expression levels of dopamine transporter (dat), tryptophan hydroxylase 1 (tph1), and serotonin reuptake transporter (sert). |
2023-12-01 |
2023-12-10 |
mouse |
| Sarita Pyatha, Haesoo Kim, Daeun Lee, Kisok Ki. Co-exposure to lead, mercury, and cadmium induces neurobehavioral impairments in mice by interfering with dopaminergic and serotonergic neurotransmission in the striatum. Frontiers in public health. vol 11. 2023-12-01. PMID:38026429. |
these findings suggest that the key proteins involved in the synthesis and reuptake of dopamine (th and dat, respectively), as well as in the synthesis and reuptake of serotonin (tph1 and sert, respectively), play crucial roles in the neurotoxic effects associated with exposure to metal mixtures. |
2023-12-01 |
2023-12-10 |
mouse |
| Sarita Pyatha, Haesoo Kim, Daeun Lee, Kisok Ki. Co-exposure to lead, mercury, and cadmium induces neurobehavioral impairments in mice by interfering with dopaminergic and serotonergic neurotransmission in the striatum. Frontiers in public health. vol 11. 2023-12-01. PMID:38026429. |
in conclusion, this study demonstrates that simultaneous exposure to different metals can impact key enzymes involved in dopaminergic and serotonergic neurotransmission processes, leading to disruptions in dopamine and serotonin homeostasis and consequently a range of detrimental neurobehavioral effects. |
2023-12-01 |
2023-12-10 |
mouse |
| Dmitrii S Traktirov, Ilya R Nazarov, Valeria S Artemova, Raul R Gainetdinov, Nina S Pestereva, Marina N Karpenk. Alterations in Serotonin Neurotransmission in Hyperdopaminergic Rats Lacking the Dopamine Transporter. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001881. |
the observed region-specific changes in the tissue levels of serotonin and in the expression of dopamine and serotonergic metabolism enzymes in rats with an excess of dopamine can indicate important consequences for the pharmacotherapy of drugs that modulate the dopaminergic system. |
2023-11-25 |
2023-11-28 |
rat |
| José Luis Maldonado-García, Gilberto Pérez-Sánchez, Enrique Becerril-Villanueva, Samantha Alvarez-Herrera, Lenin Pavón, Luvia Sánchez-Torres, Gabriel Gutiérrez-Ospina, Manuel Iván Girón-Pérez, Gabriela Damian-Morales, Jesús Octavio Maldonado-Tapia, Rubén López-Santiago, Martha C Moreno-Lafon. Imipramine Administration in Pharmaceuticals (Basel, Switzerland). vol 16. issue 11. 2023-11-25. PMID:38004391. |
in mouse models, it has been associated with increased levels of il-6, tnf-α, and ifn-γ, a decrease in serotonin and dopamine levels within the hippocampus, induced loss of muscle strength and equilibrium, and increased anxiety and hopelessness. |
2023-11-25 |
2023-11-28 |
mouse |
| Pooja Gusain, Makiko Taketoshi, Yoko Tominaga, Takashi Tominag. Functional dissection of ipsilateral and contralateral neural activity propagation using voltage-sensitive dye imaging in mouse prefrontal cortex. eNeuro. 2023-11-17. PMID:37977827. |
these findings highlight the importance of understanding the pfc functional anatomy in evaluating neuromodulators like serotonin and dopamine, as well as other factors related to neuropsychiatric diseases. |
2023-11-17 |
2023-11-20 |
mouse |
| O A Solovieva, M A Gruden, V S Kudrin, N P Mikhailova, V B Narkevich, V V Sherstnev, Z I Storozhev. Motor and Cognitive Functions in Aging C57BL/6 Mice: Association with Activity of the Monoaminergic Systems in the Cerebellum and Frontal Cortex. Bulletin of experimental biology and medicine. 2023-11-17. PMID:37978148. |
the levels of norepinephrine, dopamine, serotonin, and their metabolites were determined in the cerebellum and frontal cortex. |
2023-11-17 |
2023-11-20 |
mouse |