| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adnan Karim, Fareeha Anwar, Uzma Saleem, Saniya Fatima, Tariq Ismail, Ahmad J Obaidullah, Rana O Khayat, Moneerah J Alqahtani, Ifat Alsharif, Haroon Khan, Celia Vargas-De-La-Cruz, Muhammad Ajmal Sha. Administration of α-lipoic acid and silymarin attenuates aggression by modulating endocrine, oxidative stress and inflammatory pathways in mice. Metabolic brain disease. 2023-07-17. PMID:37458892. |
effect of antioxidant treatment (i.e., 21 days bid) on aggression was assessed by evaluating the changes in aggressive behavior, oxidative stress biomarkers superoxide dismutase, catalase, glutathione, nitrite and malondialdehyde (sod, cat, gsh, nitrite & mda), neurotransmitters (dopamine, nor-adrenaline and serotonin), pro-inflammatory cytokines tumor necrosis factor-α and interleukin- 6 (tnf-α & il-6) along with serum testosterone examination. |
2023-07-17 |
2023-08-14 |
mouse |
| Anjali Suman, Archisman Mahapatra, Priya Gupta, Shubhendu Shekhar Ray, Rahul Kumar Sing. Polystyrene microplastics modulated bdnf expression triggering neurotoxicity via apoptotic pathway in zebrafish embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-07-16. PMID:37454885. |
on the last day of exposure, behaviour, accumulation, embryotoxicity, acridine orange staining, antioxidant enzyme assay, acetylcholinesterase assay, nitric oxide (no) estimation, along with neurotransmitter (serotonin, dopamine) quantification and gene expression using qrt-pcr (bdnf, p53, bcl-2, caspase-3, caspase-9) were performed. |
2023-07-16 |
2023-08-14 |
human |
| Anjali Suman, Archisman Mahapatra, Priya Gupta, Shubhendu Shekhar Ray, Rahul Kumar Sing. Polystyrene microplastics modulated bdnf expression triggering neurotoxicity via apoptotic pathway in zebrafish embryos. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023-07-16. PMID:37454885. |
moreover, polystyrene microplastics exposure resulted in reduced acetylcholinesterase activity leading to elevated no concentration along with altered serotonin and dopamine levels and subsequently leading to down-regulated bdnf gene expression and modulated downstream apoptotic signalling, confirming the neurotoxicity potential of microplastics causing neuronal dysfunction. |
2023-07-16 |
2023-08-14 |
human |
| Qipeng Shi, Huaran Yang, Yangli Chen, Na Zheng, Xiaoyu Li, Xianfeng Wang, Weikai Ding, Bangjun Zhan. Developmental Neurotoxicity of Trichlorfon in Zebrafish Larvae. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37446277. |
furthermore, trichlorfon significantly inhibited ache activity, accompanied by decreased acetylcholine, dopamine and serotonin content in larvae. |
2023-07-14 |
2023-08-14 |
zebrafish |
| Rahmani Wela. Effect of Vitamin B6 on Osteoporosis Fracture. Journal of bone metabolism. vol 30. issue 2. 2023-07-14. PMID:37449347. |
vitamin b6 produces neurotransmitters such as serotonin, which helps regulate mood, and dopamine, which is involved in motivation and reward. |
2023-07-14 |
2023-08-14 |
Not clear |
| Denis Zosen, Elena Kondratskaya, Oykum Kaplan-Arabaci, Fred Haugen, Ragnhild Elisabeth Paulse. Antidepressants escitalopram and venlafaxine up-regulate BDNF promoter IV but down-regulate neurite outgrowth in differentiating SH-SY5Y neurons. Neurochemistry international. 2023-07-14. PMID:37451345. |
the pharmacological actions of these drugs generally determine the uptake and metabolism of a series of neurotransmitters, such as serotonin, norepinephrine, or dopamine, along with an increase in bdnf expression. |
2023-07-14 |
2023-08-14 |
human |
| Carla Fonseca, Miren Ettcheto, Joana Bicker, Maria José Fernandes, Amílcar Falcão, Antoni Camins, Ana Fortun. Under the umbrella of depression and Alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? Ageing research reviews. 2023-07-06. PMID:37414155. |
besides the well-known imbalance of neurotransmitter levels, including serotonin, noradrenaline, dopamine and glutamate, recent scientific evidence highlights aberrant spine density, neuroinflammation, dysregulation of neurotrophic factor levels and formation of amyloid beta (aβ) peptides, as the main physiopathological mechanisms compromised in depression and ad. |
2023-07-06 |
2023-08-14 |
Not clear |
| Kai-Chun Yang, Yuan-Hwa Cho. Molecular imaging findings for treatment resistant depression. Progress in brain research. vol 278. 2023-07-06. PMID:37414495. |
there was also limited data to demonstrate the changes in the markers of serotonin, dopamine, amyloid, and microglia over some regions in trd. |
2023-07-06 |
2023-08-14 |
Not clear |
| Haoxing Cai, Mingyue Chen, Yang Gao, Jinpeng Ruan, Chengyong He, Zhenghong Zu. Transgenerational Effects and Mechanisms of Tributyltin Exposure on Neurodevelopment in the Male Offspring of Rats. Environmental science & technology. 2023-07-05. PMID:37406193. |
additionally, f1-f3 males exhibited increased serotonin and dopamine levels and a loose arrangement of neurons in the hippocampus. |
2023-07-05 |
2023-08-14 |
rat |
| Jing Zhang, Lei Wang, Mengbo Liu, Zhenyang Y. Multi- and trans-generational effects of di-n-octyl phthalate on behavior, lifespan and reproduction of Caenorhabditis elegans through neural regulation and lipid metabolism. The Science of the total environment. 2023-07-05. PMID:37406686. |
further analysis showed close connections between effects of dop on neurotransmitters (including dopamine, acetylcholine, γ-aminobutyric acid and serotonin) and enzymes in lipid metabolism (including lipase, acetyl coa carboxylase, fatty acid synthetase, carnitine palmitoyl-transferase, glycerol phosphate acyltransferase and acetyl coa synthetase). |
2023-07-05 |
2023-08-14 |
caenorhabditis_elegans |
| Elena Missir, Patrick Begley, Maryam Jessop, Nitasha Singh, Mark Aplin, Helena McMeekin, Puja Parekh, Malgorzata Raczek, Sabina Dizdarevi. Quantitative [123]I-Ioflupane DaTSCAN single-photon computed tomography-computed tomography in Parkinsonism. Nuclear medicine communications. 2023-07-03. PMID:37395542. |
[123]i-ioflupane (datscan) binds to the presynaptic dopamine transporter (dat) and with a lower affinity to the serotonin transporter (sert). |
2023-07-03 |
2023-08-14 |
Not clear |
| Zhelun Peng, Qiu Man, Lu Meng, Sheng Wang, Hao Cai, Chuansheng Zhang, Xianyao Li, Heng Wang, Guiyu Zh. A PITX2-HTR1B pathway regulates the asymmetric development of female gonads in chickens. PNAS nexus. vol 2. issue 6. 2023-06-30. PMID:37388922. |
integrated chromatin immunoprecipitation sequencing (chip-seq) and rna sequencing (rna-seq) analyses indicated that pitx2 directly binds to the promoters of genes encoding neurotransmitter receptors and leads to left-biased expression of both serotonin and dopamine receptors. |
2023-06-30 |
2023-08-14 |
Not clear |
| Ruixi Yang, Suzhen Ye, Shuping Zhang, Hanjin Huang, Yun Zhang, Yao Yang, Shu Xie, Lin He, Yuwei Yang, Jian Sh. Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson's disease. Neuroreport. vol 34. issue 11. 2023-06-29. PMID:37384936. |
in our murine model, mptp induced a decreased level of 5-hydroxytryptamine and its metabolite 5-hydroxyindoleacetic acid (5-hiaa) in the prefrontal cortex, hippocampus, and striatum (all p < 0.05); however, it only induced a decreased level of dopamine and its metabolite homovanillic acid (hva) in the striatum (both p < 0.001), with a negative correlation in the hippocampus and a positive correlation in the cortex and striatum. |
2023-06-29 |
2023-08-14 |
mouse |
| Ruixi Yang, Suzhen Ye, Shuping Zhang, Hanjin Huang, Yun Zhang, Yao Yang, Shu Xie, Lin He, Yuwei Yang, Jian Sh. Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson's disease. Neuroreport. vol 34. issue 11. 2023-06-29. PMID:37384936. |
in the ldb, 5-hydroxytryptamine levels in the cortex and dopamine and hva levels in the striatum were negatively correlated with anxious behavior. |
2023-06-29 |
2023-08-14 |
mouse |
| Ruixi Yang, Suzhen Ye, Shuping Zhang, Hanjin Huang, Yun Zhang, Yao Yang, Shu Xie, Lin He, Yuwei Yang, Jian Sh. Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson's disease. Neuroreport. vol 34. issue 11. 2023-06-29. PMID:37384936. |
moreover, in the elevate plus-maze, 5-hydroxytryptamine and 5-hiaa in the cortex and dopamine and hva in the striatum were positively correlated with the ratio of the time spent in open arms. |
2023-06-29 |
2023-08-14 |
mouse |
| Ruixi Yang, Suzhen Ye, Shuping Zhang, Hanjin Huang, Yun Zhang, Yao Yang, Shu Xie, Lin He, Yuwei Yang, Jian Sh. Serotonin and dopamine depletion in distinct brain regions may cause anxiety in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice as a model of early Parkinson's disease. Neuroreport. vol 34. issue 11. 2023-06-29. PMID:37384936. |
the depletion of 5-hydroxytryptamine in the cortex and dopamine in the striatum may be associated with anxiety behaviors in mptp-treated mice. |
2023-06-29 |
2023-08-14 |
mouse |
| Witold Żakowski, Piotr Zawistowsk. Neurochemistry of the mammillary body. Brain structure & function. 2023-06-28. PMID:37378855. |
the following groups of substances are reviewed: (1) classical neurotransmitters (glutamate and other excitatory transmitters, gamma-aminobutyric acid, acetylcholine, serotonin, and dopamine), (2) neuropeptides (enkephalins, substance p, cocaine- and amphetamine-regulated transcript, neurotensin, neuropeptide y, somatostatin, orexins, and galanin), and (3) other substances (calcium-binding proteins and calcium sensor proteins). |
2023-06-28 |
2023-08-14 |
rat |
| Meghan Pantalia, Zhi Lin, Samantha J Tener, Bing Qiao, Grace Tang, Matthew Ulgherait, Reed O'Connor, Rebecca Delventhal, Julia Volpi, Sheyum Syed, Nissim Itzhak, Julie C Canman, María de la Paz Fernández, Mimi Shirasu-Hiz. Drosophila mutants lacking the glial neurotransmitter-modifying enzyme Ebony exhibit low neurotransmitter levels and altered behavior. Scientific reports. vol 13. issue 1. 2023-06-27. PMID:37369755. |
inhibitors of enzymes that inactivate amine neurotransmitters (dopamine, serotonin), such as catechol-o-methyltransferase (comt) and monoamine oxidase (mao), are thought to increase neurotransmitter levels and are widely used to treat parkinson's disease and psychiatric disorders, yet the role of these enzymes in regulating behavior remains unclear. |
2023-06-27 |
2023-08-14 |
drosophila_melanogaster |
| Saleh I Alaqel, Omeima Abdullah, Adnan Alharbi, Yusuf S Althobaiti, Mansour S Alturki, Sherif Ramzy, Atiah H Almalk. Guava-fruit based synthesis of carbon quantum dots for spectrofluorometric quantitative analysis of risperidone in spiked human plasma and pharmaceutical dosage forms. RSC advances. vol 13. issue 26. 2023-06-16. PMID:37323441. |
risperidone is a selective serotonin type 2 and dopamine type 2 receptor antagonist. |
2023-06-16 |
2023-08-14 |
human |
| N J Clauss, F P Mayer, W A Owens, M Vitela, K M Clarke, M A Bowman, R E Horton, D Gründemann, D Schmid, M Holy, G G Gould, W Koek, H H Sitte, L C Daw. Ethanol inhibits dopamine uptake via organic cation transporter 3: Implications for ethanol and cocaine co-abuse. Molecular psychiatry. 2023-06-12. PMID:37308680. |
cocaine increases extracellular monoamines by blocking dopamine (da), norepinephrine (ne) and serotonin (5-ht) transporters (dat, net and sert, respectively). |
2023-06-12 |
2023-08-14 |
mouse |