| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yan Ping Hui, Tao Wang, Ling Na Han, Li Bo Li, Yi Na Sun, Jian Liu, Hong Fei Qiao, Qiao Jun Zhan. Anxiolytic effects of prelimbic 5-HT(1A) receptor activation in the hemiparkinsonian rat. Behavioural brain research. vol 277. 2015-09-08. PMID:24906197. |
this study sought to assess whether unilateral lesions of the medial forebrain bundle (mfb) using 6-hydroxydopamine in rats are able to induce anxiety-like behaviors, the role of serotonin-1a (5-ht1a) receptors of the prelimbic (prl) sub-region of ventral medial prefrontal cortex in the regulation of these behaviors, the density of 5-ht neurons in the dorsal raphe nucleus (drn) and co-localization of 5-ht1a receptor and neuronal glutamate transporter eaac1-immunoreactive (eaac1-ir) cells in the prl. |
2015-09-08 |
2023-08-13 |
rat |
| Stefano Puglisi-Allegra, Diego Andolin. Serotonin and stress coping. Behavioural brain research. vol 277. 2015-09-08. PMID:25108244. |
based on growing evidence pointing to a medial prefrontal cortex-amygdala system in mediating adaptive and maladaptive stress responses, we propose a brain circuit in which serotonin neurons in the dorsal raphe depending on the crf (corticotropin releasing factor) regulatory action engage a prefrontal cortical-amygdala pathway through 5-ht1a receptors, gaba and glutamate to moderate coping behavior. |
2015-09-08 |
2023-08-13 |
human |
| Aki Takahashi, Ray X Lee, Takuji Iwasato, Shigeyoshi Itohara, Hiroshi Arima, Bernhard Bettler, Klaus A Miczek, Tsuyoshi Koid. Glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 16. 2015-07-16. PMID:25904796. |
glutamate input in the dorsal raphe nucleus as a determinant of escalated aggression in male mice. |
2015-07-16 |
2023-08-13 |
mouse |
| Dave Gagnon, Martin Paren. Distribution of VGLUT3 in highly collateralized axons from the rat dorsal raphe nucleus as revealed by single-neuron reconstructions. PloS one. vol 9. issue 2. 2014-12-28. PMID:24504335. |
our results provide the first direct evidence that the dorsal raphe nucleus ascending projections are composed of widely distributed neuronal systems, whose capacity to co-release serotonin and glutamate varies from one forebrain locus to the other. |
2014-12-28 |
2023-08-12 |
rat |
| Zhixiang Liu, Jingfeng Zhou, Yi Li, Fei Hu, Yao Lu, Ming Ma, Qiru Feng, Ju-En Zhang, Daqing Wang, Jiawei Zeng, Junhong Bao, Ji-Young Kim, Zhou-Feng Chen, Salah El Mestikawy, Minmin Lu. Dorsal raphe neurons signal reward through 5-HT and glutamate. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656254. |
dorsal raphe neurons signal reward through 5-ht and glutamate. |
2014-05-21 |
2023-08-12 |
mouse |
| Yukio Ago, Ryota Araki, Tatsunori Tanaka, Asuka Sasaga, Saki Nishiyama, Kazuhiro Takuma, Toshio Matsud. Role of social encounter-induced activation of prefrontal serotonergic systems in the abnormal behaviors of isolation-reared mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 8. 2014-02-13. PMID:23426384. |
a 5-ht1a receptor agonist, a metabotropic glutamate 2/3 receptor agonist, and a gamma-aminobutyric acid a receptor agonist attenuated isolation-induced aggressive behaviors and encounter-induced hyperactivity, c-fos expression in the prefrontal cortex and dorsal raphe nucleus, and increases in prefrontal 5-ht levels. |
2014-02-13 |
2023-08-12 |
mouse |
| Erwan Le Maître, Swapnali Shantaram Barde, Miklos Palkovits, Rochellys Diaz-Heijtz, Tomas G M Hökfel. Distinct features of neurotransmitter systems in the human brain with focus on the galanin system in locus coeruleus and dorsal raphe. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 6. 2013-04-09. PMID:23341594. |
using riboprobe in situ hybridization, we studied the localization of the transcripts for the neuropeptide galanin and its receptors (galr1-r3), tryptophan hydroxylase 2, tyrosine hydroxylase, and nitric oxide synthase as well as the three vesicular glutamate transporters (vglut 1-3) in the locus coeruleus (lc) and the dorsal raphe nucleus (drn) regions of postmortem human brains. |
2013-04-09 |
2023-08-12 |
human |
| Julieta Garduño, Luis Galindo-Charles, Javier Jiménez-Rodríguez, Elvira Galarraga, Dagoberto Tapia, Stefan Mihailescu, Salvador Hernandez-Lope. Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 43. 2013-01-07. PMID:23100436. |
presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. |
2013-01-07 |
2023-08-12 |
rat |
| Annamária Fejes, Arpád Párdutz, József Toldi, László Vécse. Kynurenine metabolites and migraine: experimental studies and therapeutic perspectives. Current neuropharmacology. vol 9. issue 2. 2012-08-23. PMID:22131946. |
one of the key molecules involved in migraine is glutamate, whose receptors are found on the first-, second- and third-order trigeminal neurones and are also present in the migraine generators, including the dorsal raphe nucleus, nucleus raphe magnus, locus coeruleus and periaqueductal grey matter. |
2012-08-23 |
2023-08-12 |
Not clear |
| LaTasha K Crawford, Caryne P Craige, Sheryl G Bec. Glutamatergic input is selectively increased in dorsal raphe subfield 5-HT neurons: role of morphology, topography and selective innervation. The European journal of neuroscience. vol 34. issue 11. 2012-04-04. PMID:22098248. |
characterization of glutamatergic input to dorsal raphe (dr) serotonin (5-ht) neurons is crucial for understanding how the glutamate and 5-ht systems interact in psychiatric disorders. |
2012-04-04 |
2023-08-12 |
mouse |
| Keiko Ohoyama, Satoshi Yamamura, Tatsuya Hamaguchi, Masanori Nakagawa, Eishi Motomura, Takashi Shiroyama, Hisashi Tanii, Motohiro Okad. Effect of novel atypical antipsychotic, blonanserin, on extracellular neurotransmitter level in rat prefrontal cortex. European journal of pharmacology. vol 653. issue 1-3. 2011-05-02. PMID:21147094. |
to clarify the mechanisms of action of blonanserin, an atypical antipsychotic drug, we studied the effects of systemic administration of blonanserin and risperidone on extracellular levels of norepinephrine, dopamine, serotonin, gaba and glutamate in the medial prefrontal cortex using microdialysis, and neuronal firing in the ventral tegmental area, locus coeruleus, dorsal raphe nucleus and mediodorsal thalamic nucleus using radiotelemetry. |
2011-05-02 |
2023-08-12 |
rat |
| Silke Heinisch, Lynn G Kirb. SDF-1alpha/CXCL12 enhances GABA and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. Neuropharmacology. vol 58. issue 2. 2010-04-13. PMID:19755127. |
sdf-1alpha/cxcl12 enhances gaba and glutamate synaptic activity at serotonin neurons in the rat dorsal raphe nucleus. |
2010-04-13 |
2023-08-12 |
rat |
| K G Common. Locally collateralizing glutamate neurons in the dorsal raphe nucleus responsive to substance P contain vesicular glutamate transporter 3 (VGLUT3). Journal of chemical neuroanatomy. vol 38. issue 4. 2010-01-26. PMID:19467322. |
locally collateralizing glutamate neurons in the dorsal raphe nucleus responsive to substance p contain vesicular glutamate transporter 3 (vglut3). |
2010-01-26 |
2023-08-12 |
Not clear |
| K G Common. Locally collateralizing glutamate neurons in the dorsal raphe nucleus responsive to substance P contain vesicular glutamate transporter 3 (VGLUT3). Journal of chemical neuroanatomy. vol 38. issue 4. 2010-01-26. PMID:19467322. |
the serotonergic dorsal raphe nucleus (dr) is an area enriched with cell bodies and axons containing the third vesicular glutamate transporter, vglut3. |
2010-01-26 |
2023-08-12 |
Not clear |
| Lesley A Colgan, Ilva Putzier, Edwin S Levita. Activity-dependent vesicular monoamine transporter-mediated depletion of the nucleus supports somatic release by serotonin neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 50. 2010-01-26. PMID:20016104. |
glutamate receptor activation in dorsal raphe brain slice evoked somatic release that was mediated solely by vesicle exocytosis. |
2010-01-26 |
2023-08-12 |
Not clear |
| Ibolya Bodnár, Zsuzsanna Bánky, Dóra Zelena, Béla Halás. Glutamate receptor antagonist infused into the hypothalamic suprachiasmatic nuclei interferes with the diurnal fluctuations in plasma prolactin and corticosterone levels and injected into the mesencephalic dorsal raphe nucleus attenuates the suckling stimulus-induced release of prolactin of the rat. Brain research bulletin. vol 80. issue 1-2. 2009-11-02. PMID:19539728. |
glutamate receptor antagonist infused into the hypothalamic suprachiasmatic nuclei interferes with the diurnal fluctuations in plasma prolactin and corticosterone levels and injected into the mesencephalic dorsal raphe nucleus attenuates the suckling stimulus-induced release of prolactin of the rat. |
2009-11-02 |
2023-08-12 |
rat |
| Jesse Jackson, Brian H Bland, Michael C Antl. Nonserotonergic projection neurons in the midbrain raphe nuclei contain the vesicular glutamate transporter VGLUT3. Synapse (New York, N.Y.). vol 63. issue 1. 2009-06-16. PMID:18925658. |
recent studies have reported that the vesicular glutamate transporter vglut3 is found in both serotonergic and nonserotonergic neurons in both the median raphe (mr) and dorsal raphe (dr) nuclei. |
2009-06-16 |
2023-08-12 |
Not clear |
| Maria Waselus, Elisabeth J Van Bockstael. Co-localization of corticotropin-releasing factor and vesicular glutamate transporters within axon terminals of the rat dorsal raphe nucleus. Brain research. vol 1174. 2008-03-10. PMID:17825268. |
co-localization of corticotropin-releasing factor and vesicular glutamate transporters within axon terminals of the rat dorsal raphe nucleus. |
2008-03-10 |
2023-08-12 |
rat |
| S E Gartside, A J Cole, A P Williams, R McQuade, S J Judg. AMPA and NMDA receptor regulation of firing activity in 5-HT neurons of the dorsal and median raphe nuclei. The European journal of neuroscience. vol 25. issue 10. 2007-08-17. PMID:17509083. |
here, we used extracellular single unit recording in midbrain slices to examine glutamate receptor mediated effects on 5-ht neuronal activity in the dorsal raphe nucleus (drn) and the median raphe nucleus (mrn). |
2007-08-17 |
2023-08-12 |
Not clear |
| Rui Tao, Sidney B Auerbac. mu-Opioids disinhibit and kappa-opioids inhibit serotonin efflux in the dorsal raphe nucleus. Brain research. vol 1049. issue 1. 2005-11-15. PMID:15935332. |
thus, we used microdialysis in the dorsal raphe nucleus (drn) of freely behaving rats to study the effect of gaba and glutamate receptor antagonists on opioid-induced changes in 5-ht efflux. |
2005-11-15 |
2023-08-12 |
rat |