| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saida Oubraim, Roh-Yu Shen, Samir Haj-Dahman. Oxytocin excites dorsal raphe serotonin neurons and bidirectionally gates their glutamate synapses. iScience. vol 26. issue 5. 2023-05-30. PMID:37250336. |
oxytocin (oxt) modulates wide spectrum of social and emotional behaviors via modulation of numerous neurotransmitter systems, including serotonin (5-ht). |
2023-05-30 |
2023-08-14 |
Not clear |
| Aya A Ghazy, Omar A Soliman, Aya I Elbahnasi, Aya Y Alawy, Amira Ma Mansour, Mennatallah A Gowaye. Role of Oxytocin in Different Neuropsychiatric, Neurodegenerative, and Neurodevelopmental Disorders. Reviews of physiology, biochemistry and pharmacology. 2022-11-23. PMID:36416982. |
oxytocin, a peptide hormone synthesized in the hypothalamus, is released into different brain regions, acting as a neurotransmitter. |
2022-11-23 |
2023-08-14 |
Not clear |
| Yangsik Kim, Esther Yang, Hyun Ki. Impaired prepulse inhibition in mice with IRSp53 deletion in modulatory neurotransmitter neurons including dopamine, acetylcholine, oxytocin, and serotonin. Biochemical and biophysical research communications. vol 586. 2021-12-06. PMID:34839189. |
impaired prepulse inhibition in mice with irsp53 deletion in modulatory neurotransmitter neurons including dopamine, acetylcholine, oxytocin, and serotonin. |
2021-12-06 |
2023-08-13 |
mouse |
| Kazunori Sasaki, Farhana Ferdousi, Satoshi Fukumitsu, Hidetoshi Kuwata, Hiroko Isod. Antidepressant- and anxiolytic-like activities of Rosmarinus officinalis extract in rodent models: Involvement of oxytocinergic system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 144. 2021-11-24. PMID:34653760. |
oxytocin (oxt), a neuropeptide involved in mammal reproductive and prosocial behaviors, has been reported to interact with various stressor-provoked neurobiological changes, including neuroendocrine, neurotransmitter, and inflammatory processes. |
2021-11-24 |
2023-08-13 |
Not clear |
| Congcong Liu, Chunmei Lan, Keshuang Li, Feng Zhou, Shuxia Yao, Lei Xu, Ning Yang, Xinqi Zhou, Jiaxin Yang, Xue Yong, Yina Ma, Dirk Scheele, Keith M Kendrick, Benjamin Becke. Oxytocinergic Modulation of Threat-Specific Amygdala Sensitization in Humans Is Critically Mediated by Serotonergic Mechanisms. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 11. 2021-11-18. PMID:33894423. |
overarching conceptualizations propose that the complex social-emotional effects of oxytocin (oxt) in humans are partly mediated by interactions with other neurotransmitter systems. |
2021-11-18 |
2023-08-13 |
Not clear |
| Yuta Kodama, Ichidai Tanaka, Tatsuhiro Sato, Kazumi Hori, Soei Gen, Masahiro Morise, Daisuke Matsubara, Mitsuo Sato, Yoshitaka Sekido, Naozumi Hashimot. Oxytocin receptor is a promising therapeutic target of malignant mesothelioma. Cancer science. vol 112. issue 9. 2021-09-14. PMID:34115916. |
overexpression of oxytocin receptor (oxtr), which is a g-protein-coupled receptor for the hormone and neurotransmitter oxytocin, mrna was distinctively identified in mm cell lines. |
2021-09-14 |
2023-08-13 |
Not clear |
| Hans-Gert Bernstein, Gerburg Keilhoff, Johann Steine. The implications of hypothalamic abnormalities for schizophrenia. Handbook of clinical neurology. vol 182. 2021-07-28. PMID:34266587. |
further, increased or decreased expression of hypothalamic peptides such as oxytocin, vasopressin, several factors involved in the regulation of appetite and satiety, endogenous opiates, products of schizophrenia susceptibility genes as well as of enzymes involved in neurotransmitter and neuropeptide metabolism have been reported in schizophrenia and/or animal models of the disease. |
2021-07-28 |
2023-08-13 |
Not clear |
| Qingmin Kong, Botao Wang, Peijun Tian, Xiu Li, Jianxin Zhao, Hao Zhang, Wei Chen, Gang Wan. Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation. Food & function. vol 12. issue 6. 2021-06-01. PMID:33629689. |
while improving autistic-like behavioral symptoms, we found l. helveticus ccfm1076 was more beneficial in regulating 5ht anabolism and catabolism, balancing excitatory and inhibitory neurotransmitter release in the pns and cns, and increasing oxytocin (ot) synthesis in the hypothalamus. |
2021-06-01 |
2023-08-13 |
rat |
| Constantina Theofanopoulou, Gregory Gedman, James A Cahill, Cedric Boeckx, Erich D Jarvi. Universal nomenclature for oxytocin-vasotocin ligand and receptor families. Nature. vol 592. issue 7856. 2021-05-12. PMID:33911268. |
oxytocin (oxt; hereafter ot) and arginine vasopressin or vasotocin (avp or vt; hereafter vt) are neurotransmitter ligands that function through specific receptors to control diverse functions |
2021-05-12 |
2023-08-13 |
Not clear |
| Lola Welsch, Julie Bailly, Emmanuel Darcq, Brigitte Lina Kieffe. The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models. Biological psychiatry. vol 87. issue 1. 2021-01-06. PMID:31521334. |
behavioral rodent models have successfully recapitulated behavioral signs of the oud-related negative affect, and several neurotransmitter systems were identified (i.e., serotonin, dynorphin, corticotropin-releasing factor, oxytocin). |
2021-01-06 |
2023-08-13 |
human |
| Milorad Ivetic, Anirban Bhattacharyya, Hana Zemkov. P2X2 Receptor Expression and Function Is Upregulated in the Rat Supraoptic Nucleus Stimulated Through Refeeding After Fasting. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31297050. |
magnocellular neurons in the supraoptic nucleus (son), which synthesize and release arginine vasopressin (avp) and oxytocin (ot), express several subtypes of atp-stimulated purinergic p2x receptors (p2xr) that modulate neuronal activity as well as neurotransmitter and hormone release. |
2020-09-30 |
2023-08-13 |
rat |
| Margarita Sala, Kihwan Han, Summer Acevedo, Daniel C Krawczyk, Carrie J McAdam. Oxytocin Receptor Polymorphism Decreases Midline Neural Activations to Social Stimuli in Anorexia Nervosa. Frontiers in psychology. vol 9. 2020-09-29. PMID:30542304. |
oxytocin is a neurotransmitter related to both feeding and social behavior; anorexia nervosa is a psychiatric illness defined by reduced food intake, weight loss, and problems in social perceptions. |
2020-09-29 |
2023-08-13 |
Not clear |
| Yu Fu, Richard A Depu. A novel neurobehavioral framework of the effects of positive early postnatal experience on incentive and consummatory reward sensitivity. Neuroscience and biobehavioral reviews. vol 107. 2020-07-28. PMID:31545989. |
the heterogeneity of the construct of reward and the underlying neurotransmitter systems (i.e., dopamine in incentive reward, opioids in consummatory reward, and oxytocin in orienting the reward systems to social cues) are first described as a means of organizing the discussion. |
2020-07-28 |
2023-08-13 |
Not clear |
| Leda Kovatsi, Kakia Nikolao. Opioids and the hormone oxytocin. Vitamins and hormones. vol 111. 2020-03-26. PMID:31421701. |
the neuropeptide oxytocin (ΟΤ) is involved as a neurohormone, a neurotransmitter, or a neuromodulator in an extensive range of central and peripheral effects, complex emotional and social human behaviors, memory and learning processes. |
2020-03-26 |
2023-08-13 |
human |
| Seoyoung Yoon, Yong-Ku Ki. The Role of the Oxytocin System in Anxiety Disorders. Advances in experimental medicine and biology. vol 1191. 2020-02-10. PMID:32002925. |
we discuss the anxiolytic effects of oxytocin in preclinical and clinical findings, possible related neurobehavioral mechanisms (social cognition, fear learning, and extinction), related neurotransmitter and neuroendocrine systems (hypothalamus-pituitary-adrenal axis, serotoninergic, and gabaergic systems), and studies regarding plasma levels of oxytocin, genetic and epigenetic findings, and effects of intranasal oxytocin in dsm-5 anxiety disorder (primarily social anxiety disorder and separation anxiety disorder) patients. |
2020-02-10 |
2023-08-13 |
human |
| Leng, Russel. Coming to term with GABA The Journal of physiology. vol 516 (Pt 2). 2019-11-20. PMID:10087358. |
gaba is an important neurotransmitter for oxytocin cells about 45 % of all synapses onto them contain gaba, and the total number of gaba synapses in the supraoptic nucleus is substantially higher in lactating animals than in virgins (el majdoubi et al. |
2019-11-20 |
2023-08-12 |
rat |
| Betty R McConn, Anna Koskinen, D Michael Denbow, Elizabeth R Gilbert, Paul B Siegel, Mark A Clin. Central injection of oxytocin reduces food intake and affects hypothalamic and adipose tissue gene expression in chickens. Domestic animal endocrinology. vol 67. 2019-08-13. PMID:30660023. |
oxytocin (ot) is a well-characterized neurotransmitter that participates in a wide range of physiological processes including the inhibition of food intake. |
2019-08-13 |
2023-08-13 |
Not clear |
| Hans-Gert Bernstein, Henrik Dobrowolny, Bernhard Bogerts, Gerburg Keilhoff, Johann Steine. The hypothalamus and neuropsychiatric disorders: psychiatry meets microscopy. Cell and tissue research. vol 375. issue 1. 2019-05-16. PMID:29767278. |
gross anatomical abnormalities (volume changes of the third ventricle, the hypothalamus, and its nuclei) and alterations at the cellular level (loss of neurons, increased or decreased expression of hypothalamic peptides such as oxytocin, vasopressin, corticotropin-releasing hormone, and other regulatory factors as well as of enzymes involved in neurotransmitter and neuropeptide metabolism) have been reported in schizophrenia and/or depression. |
2019-05-16 |
2023-08-13 |
Not clear |
| Jonathan K Wynn, Michael F Green, Gerhard Hellemann, Eric A Reavis, Stephen R Marde. A dose-finding study of oxytocin using neurophysiological measures of social processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 44. issue 2. 2019-02-11. PMID:30082892. |
recent interest has focused on oxytocin (ot), a neurotransmitter that promotes social processing, to improve social functioning in people with schizophrenia. |
2019-02-11 |
2023-08-13 |
human |
| Jee Hyun Kim, Christina J Perry, Despina E Ganella, Heather B Madse. Postnatal development of neurotransmitter systems and their relevance to extinction of conditioned fear. Neurobiology of learning and memory. vol 138. 2018-02-22. PMID:27818267. |
major neurotransmitter systems including the glutamatergic and gabaergic systems, the monoamines, the endogenous opioid and cannabinoid systems, acetylcholines, and neuropeptides such as oxytocin have all been identified to play some role in extinction of fear memories and have been covered in this review. |
2018-02-22 |
2023-08-13 |
Not clear |