| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gianfranco Cosenza, Nicolò P P Macciotta, Anna Nudda, Angelo Coletta, Luigi Ramunno, Alfredo Pauciull. A novel polymorphism in the oxytocin receptor encoding gene (OXTR) affects milk fatty acid composition in Italian Mediterranean river buffalo. The Journal of dairy research. vol 84. issue 2. 2017-08-28. PMID:28524009. |
the oxytocin receptor, also known as oxtr, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin and the complex oxytocin-oxytocin receptor plays an important role in the uterus during calving. |
2017-08-28 |
2023-08-13 |
Not clear |
| N Singewald, C Schmuckermair, N Whittle, A Holmes, K J Ressle. Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders. Pharmacology & therapeutics. vol 149. 2015-12-15. PMID:25550231. |
the purpose of this review is to outline the literature showing how pharmacological interventions targeting neurotransmitter systems including serotonin, dopamine, noradrenaline, histamine, glutamate, gaba, cannabinoids, neuropeptides (oxytocin, neuropeptides y and s, opioids) and other targets (neurotrophins bdnf and fgf2, glucocorticoids, l-type-calcium channels, epigenetic modifications) as well as their downstream signaling pathways, can augment fear extinction and strengthen extinction memory persistently in preclinical models. |
2015-12-15 |
2023-08-13 |
Not clear |
| J S Lonstein, J Maguire, G Meinlschmidt, I D Neuman. Emotion and mood adaptations in the peripartum female:complementary contributions of GABA and oxytocin. Journal of neuroendocrinology. vol 26. issue 10. 2015-05-20. PMID:25074620. |
the neurochemical systems underlying these aspects of maternal emotional and mood states include the inhibitory neurotransmitter gaba and the neuropeptide oxytocin (oxt). |
2015-05-20 |
2023-08-13 |
Not clear |
| Robyn J McQuaid, Opal A McInnis, Alfonso Abizaid, Hymie Anisma. Making room for oxytocin in understanding depression. Neuroscience and biobehavioral reviews. vol 45. 2015-04-16. PMID:25025656. |
this view is supported by evidence that oxytocin interacts with various neuroendocrine, neurotransmitter, and inflammatory processes that have previously been implicated in depression. |
2015-04-16 |
2023-08-13 |
Not clear |
| Laura C Politte, Charles A Henry, Christopher J McDougl. Psychopharmacological interventions in autism spectrum disorder. Harvard review of psychiatry. vol 22. issue 2. 2014-12-01. PMID:24614763. |
psychopharmacological interventions in development for core symptoms of autism include those that target the glutamatergic and gabaergic neurotransmitter systems and the neuropeptide oxytocin. |
2014-12-01 |
2023-08-12 |
Not clear |
| Frank Krueger, Raja Parasuraman, Lara Moody, Peter Twieg, Ewart de Visser, Kevin McCabe, Martin O'Hara, Mary R Le. Oxytocin selectively increases perceptions of harm for victims but not the desire to punish offenders of criminal offenses. Social cognitive and affective neuroscience. vol 8. issue 5. 2014-01-29. PMID:22368214. |
the neuropeptide oxytocin functions as a hormone and neurotransmitter and facilitates complex social cognition and approach behavior. |
2014-01-29 |
2023-08-12 |
human |
| Carlos Dombret, Tuan Nguyen, Olivier Schakman, Jacques L Michaud, Hélène Hardin-Pouzet, Mathieu J M Bertrand, Olivier De Backe. Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus. Human molecular genetics. vol 21. issue 21. 2013-04-03. PMID:22865874. |
oxytocin (ot), which is produced in the hypothalamus, can act as a neurotransmitter that reduces anxiety, promotes social behaviors and regulates food intake. |
2013-04-03 |
2023-08-12 |
mouse |
| David Diodati, Lee Cyn-Ang, Andrew Kertesz, Elizabeth Finge. Pathologic evaluation of the supraoptic and paraventricular nuclei in dementia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 39. issue 2. 2012-07-11. PMID:22343156. |
the neuropeptide oxytocin, produced in the supraoptic (son) and paraventricular nuclei (pvn) of the hypothalamus, is now understood to function as a neurotransmitter critical for various aspects of social cognition and pro-social behaviour. |
2012-07-11 |
2023-08-12 |
Not clear |
| Julia S Sen. Posttraumatic oxytocin dysregulation: is it a link among posttraumatic self disorders, posttraumatic stress disorder, and pelvic visceral dysregulation conditions in women? Journal of trauma & dissociation : the official journal of the International Society for the Study of Dissociation (ISSD). vol 11. issue 4. 2011-02-04. PMID:20938865. |
this article explicates a theory that oxytocin, a sexually dimorphic neurotransmitter and paracrine hormone, is a plausible mechanism linking early relational trauma with posttraumatic self disorders (e.g., dissociation, somatization, and interpersonal sensitivity), posttraumatic stress disorder, and pelvic visceral dysregulation disorders (e.g., irritable bowel syndrome, chronic pelvic pain, interstitial cystitis, and hyperemesis gravidarum). |
2011-02-04 |
2023-08-12 |
Not clear |
| Sarina M Rodrigues, Laura R Saslow, Natalia Garcia, Oliver P John, Dacher Keltne. Oxytocin receptor genetic variation relates to empathy and stress reactivity in humans. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 50. 2010-02-12. PMID:19934046. |
oxytocin, a peptide that functions as both a hormone and neurotransmitter, has broad influences on social and emotional processing throughout the body and the brain. |
2010-02-12 |
2023-08-12 |
Not clear |
| Douglas C Bittel, Nataliya Kibiryeva, Majed Dasouki, Joan H M Knoll, Merlin G Butle. A 9-year-old male with a duplication of chromosome 3p25.3p26.2: clinical report and gene expression analysis. American journal of medical genetics. Part A. vol 140. issue 6. 2006-05-30. PMID:16470700. |
this region of chromosome 3p contains genes which contribute to obesity and behavioral problems, most notably, ghrelin (ghrl), an oxytocin receptor (oxtr), solute carrier family six members (gamma-aminobutyric acid (gaba) neurotransmitter transporters, slc6a1 and slc6a11), and peroxisome proliferator-activated receptor gamma (pparg). |
2006-05-30 |
2023-08-12 |
human |
| Barry R Komisaruk, Giorgio Sanson. Neural pathways mediating vaginal function: the vagus nerves and spinal cord oxytocin. Scandinavian journal of psychology. vol 44. issue 3. 2004-01-06. PMID:12914587. |
it has led to an understanding of: (1) the neuroanatomical and neurochemical basis of a novel and potent pain-blocking mechanism; (2) likely neuroanatomical pathways mediating both the ferguson reflex and a specific autonomic response - the pupil-dilating effect of vcs; (3) a role for oxytocin as a putative central nervous system neurotransmitter that stimulates autonomic sympathetic preganglionic neurons within the spinal cord; and (4) a novel pathway that can convey sensory activity from the cervix, adequate to induce orgasm, via the vagus nerves. |
2004-01-06 |
2023-08-12 |
rat |
| G R Sansone, B R Komisaru. Evidence that oxytocin is an endogenous stimulator of autonomic sympathetic preganglionics: the pupillary dilatation response to vaginocervical stimulation in the rat. Brain research. vol 898. issue 2. 2001-07-26. PMID:11306012. |
since activation of autonomic sympathetic preganglionic neurons in the thoracic spinal cord produces pupillary dilatation, we propose that oxytocin is a central nervous system neurotransmitter that stimulates these neurons directly, or perhaps indirectly, and thus is a mediator of vs-produced pupillary dilatation. |
2001-07-26 |
2023-08-12 |
rat |
| H Shi, T J Bartnes. Catecholaminergic enzymes, vasopressin and oxytocin distribution in Siberian hamster brain. Brain research bulletin. vol 53. issue 6. 2001-05-10. PMID:11179851. |
because no atlas of neurotransmitter distribution exists for this species, the purpose of the present study was to map the distribution of cell bodies containing catecholaminergic synthetic enzymes (tyrosine hydroxylase and dopamine-beta-hydroxylase) and several neurotransmitters (arginine vasopressin and oxytocin) in siberian hamster brain using immunocytochemistry. |
2001-05-10 |
2023-08-12 |
Not clear |
| R M Buijs, S J Chun, A Niijima, H J Romijn, K Naga. Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake. The Journal of comparative neurology. vol 431. issue 4. 2001-05-03. PMID:11223811. |
several cell groups project to both branches of the autonomic nervous system, sometimes even the same neurotransmitter is used, e.g., oxytocin neurons in the paraventricular nucleus and melanin-concentrating hormone and orexin neurons in the lateral hypothalamus project to both the dmv and spn neurons. |
2001-05-03 |
2023-08-12 |
Not clear |
| J E Stern, S Hestrin, W E Armstron. Enhanced neurotransmitter release at glutamatergic synapses on oxytocin neurones during lactation in the rat. The Journal of physiology. vol 526 Pt 1. 2000-11-08. PMID:10878104. |
enhanced neurotransmitter release at glutamatergic synapses on oxytocin neurones during lactation in the rat. |
2000-11-08 |
2023-08-12 |
rat |
| S L Bealer, W R Crowle. Neurotransmitter interaction in release of intranuclear oxytocin in magnocellular nuclei of the hypothalamus. Annals of the New York Academy of Sciences. vol 897. 2000-03-06. PMID:10676447. |
neurotransmitter interaction in release of intranuclear oxytocin in magnocellular nuclei of the hypothalamus. |
2000-03-06 |
2023-08-12 |
rat |
| C Breton, H H Zing. Expression and region-specific regulation of the oxytocin receptor gene in rat brain. Endocrinology. vol 138. issue 5. 1997-05-09. PMID:9112379. |
the neuropeptide oxytocin (ot) exerts its various neurotransmitter functions via specific ot receptors (otrs) that have been localized to distinct brain regions, including the ventromedial hypothalamus, the bed nucleus of stria terminalis, the amygdala, the subiculum, the hippocampus, and the olfactory nuclei. |
1997-05-09 |
2023-08-12 |
rat |
| L M Flanagan-Cato, S J Fluhart. Guanine nucleotide regulation and cation sensitivity of agonist binding to rat brain oxytocin receptors. Brain research. vol 701. issue 1-2. 1996-10-25. PMID:8925301. |
the neuropeptide oxytocin (ot) is synthesized in the hypothalamus and can be released either as a hormone from the neurohypophysis or as a neurotransmitter in various brain regions. |
1996-10-25 |
2023-08-12 |
rat |
| S L Parker, W R Crowle. Stimulation of oxytocin release in the lactating rat by central excitatory amino acid mechanisms: evidence for specific involvement of R,S-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid-sensitive glutamate receptors. Endocrinology. vol 133. issue 6. 1994-01-06. PMID:7694846. |
to examine whether an excitatory amino acid (eaa) neurotransmitter may influence the secretion of oxytocin (ot), agonists and antagonists selective for three major groups of eaa receptors were microinjected into the area of right supraoptic nucleus (son) of conscious unrestrained lactating rats. |
1994-01-06 |
2023-08-12 |
rat |