| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tangfeng Su, Lei Pe. Acupuncture and oxytocinergic system: The promising treatment for autism. Translational neuroscience. vol 12. issue 1. 2021-02-27. PMID:33633868. |
in view of these findings, we conclude that acupuncture may produce therapeutic effects on autism by triggering the hypothalamic oxytocin system, which in turn activates the release of neurotransmitters such as endocannabinoids, dopamine and serotonin. |
2021-02-27 |
2023-08-13 |
mouse |
| Lola Welsch, Julie Bailly, Emmanuel Darcq, Brigitte Lina Kieffe. The Negative Affect of Protracted Opioid Abstinence: Progress and Perspectives From Rodent Models. Biological psychiatry. vol 87. issue 1. 2021-01-06. PMID:31521334. |
behavioral rodent models have successfully recapitulated behavioral signs of the oud-related negative affect, and several neurotransmitter systems were identified (i.e., serotonin, dynorphin, corticotropin-releasing factor, oxytocin). |
2021-01-06 |
2023-08-13 |
human |
| Anastasia Repouskou, Anastasia-Konstantina Papadopoulou, Emily Panagiotidou, Panagiotis Trichas, Christian Lindh, Åke Bergman, Chris Gennings, Carl-Gustaf Bornehag, Joëlle Rüegg, Efthymia Kitraki, Antonios Stamataki. Long term transcriptional and behavioral effects in mice developmentally exposed to a mixture of endocrine disruptors associated with delayed human neurodevelopment. Scientific reports. vol 10. issue 1. 2020-12-08. PMID:32518293. |
the expression of corticosterone receptors, their regulator fkbp5, corticotropin releasing hormone and its receptor, oxytocin and its receptor, estrogen receptor beta, serotonin receptors (htr1a, htr2a) and glutamate receptor subunit grin2b, were modified in the limbic system of adult animals, in a region-specific, sexually-dimorphic and experience-dependent manner. |
2020-12-08 |
2023-08-13 |
mouse |
| Monika M Stojek, Lauren B McSweeney, Sheila A M Rauc. Neuroscience Informed Prolonged Exposure Practice: Increasing Efficiency and Efficacy Through Mechanisms. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30515086. |
we consider various enhancements that have been used with pe, including serotonin reuptake inhibitors (ssris), d-cycloserine (dcs), allopregnanolone (allo) and propranolol, repetitive transcranial magnetic stimulation (rtms), oxytocin and mdma. |
2020-10-01 |
2023-08-13 |
Not clear |
| Eiichi Kumamot. Cellular Mechanisms for Antinociception Produced by Oxytocin and Orexins in the Rat Spinal Lamina II-Comparison with Those of Other Endogenous Pain Modulators. Pharmaceuticals (Basel, Switzerland). vol 12. issue 3. 2020-10-01. PMID:31527474. |
this review article will mention cellular mechanisms for antinociception produced by oxytocin, orexins a and b, and discuss similarity and difference in antinociceptive mechanisms among the hypothalamic neuropeptides and other endogenous pain modulators (opioids, nociceptin, adenosine, adenosine 5'-triphosphate (atp), noradrenaline, serotonin, dopamine, somatostatin, cannabinoids, galanin, substance p, bradykinin, neuropeptide y and acetylcholine) exhibiting a change in membrane potential, excitatory or inhibitory transmission in the spinal lamina ii neurons. |
2020-10-01 |
2023-08-13 |
rat |
| Dasiel O Borroto-Escuela, Jens Carlsson, Patricia Ambrogini, Manuel Narváez, Karolina Wydra, Alexander O Tarakanov, Xiang Li, Carmelo Millón, Luca Ferraro, Riccardo Cuppini, Sergio Tanganelli, Fang Liu, Malgorzata Filip, Zaida Diaz-Cabiale, Kjell Fux. Understanding the Role of GPCR Heteroreceptor Complexes in Modulating the Brain Networks in Health and Disease. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28270751. |
neuromodulation of neuronal networks in schizophrenia via da, adenosine, glutamate, 5-ht and neurotensin peptides and oxytocin, involving a2ar-d2r, d2r-nmdar, a2ar-d2r-mglur5, d2r-5-ht2a and d2r-oxytocinr heteroreceptor complexes opens up a new world of d2r protomer targets in the listed heterocomplexes for treatment of positive, negative and cognitive symptoms of schizophrenia. |
2020-09-30 |
2023-08-13 |
Not clear |
| Asmaa Ms Gomaa, Heba M Galal, Amal T Abou-Elgai. Neuroprotective effects of melatonin administration against chronic immobilization stress in rats. International journal of physiology, pathophysiology and pharmacology. vol 9. issue 2. 2020-09-30. PMID:28533888. |
the mel-treated stressed group showed reduction of both relative adrenal weight and the serum corticosterone levels, suppression of the anxiety-like behavior, increased levels of serotonin, noradrenaline and oxytocin in the frontal cortex, and improved histopathological structure and decreased chromogranin a (cga) protein expression in the frontal cortex when compared with the chronically stressed group. |
2020-09-30 |
2023-08-13 |
rat |
| Andrea Bonassi, Tommaso Ghilardi, Anna Truzzi, Ilaria Cataldo, Atiqah Azhari, Peipei Setoh, Kazuyuki Shinohara, Gianluca Esposit. Dataset on genetic and physiological adults׳ responses to social distress. Data in brief. vol 13. 2020-09-30. PMID:28748210. |
here, we report data to investigate the interaction between genetic factors, (oxytocin receptor (oxtr) and serotonin transporter (5-httlpr) polymorphisms), and adult interactional patterns in shaping physiological responses to social distress. |
2020-09-30 |
2023-08-13 |
human |
| Neil Levy, Thomas Douglas, Guy Kahane, Sylvia Terbeck, Philip J Cowen, Miles Hewstone, Julian Savulesc. Are You Morally Modified?: The Moral Effects of Widely Used Pharmaceuticals. Philosophy, psychiatry, & psychology : PPP. vol 21. issue 2. 2020-09-29. PMID:25892904. |
we review current evidence on the moral effects of three widely used drugs or drug types: (i) propranolol, (ii) selective serotonin reuptake inhibitors, and (iii) drugs that effect oxytocin physiology. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rosa Marotta, Maria C Risoleo, Giovanni Messina, Lucia Parisi, Marco Carotenuto, Luigi Vetri, Michele Roccell. The Neurochemistry of Autism. Brain sciences. vol 10. issue 3. 2020-09-28. PMID:32182969. |
in this review, we aim to delineate the state-of-the-art main research findings about the neurochemical alterations in autism etiology, and focuses on gamma aminobutyric acid (gaba) and glutamate, serotonin, dopamine, n-acetyl aspartate, oxytocin and arginine-vasopressin, melatonin, vitamin d, orexin, endogenous opioids, and acetylcholine. |
2020-09-28 |
2023-08-13 |
Not clear |
| Michael Maes, George Anderson, Susana R Betancort Medina, Moonsang Seo, Johanna O Ojal. Integrating Autism Spectrum Disorder Pathophysiology: Mitochondria, Vitamin A, CD38, Oxytocin, Serotonin and Melatonergic Alterations in the Placenta and Gut. Current pharmaceutical design. vol 25. issue 41. 2020-06-17. PMID:31682209. |
integrating autism spectrum disorder pathophysiology: mitochondria, vitamin a, cd38, oxytocin, serotonin and melatonergic alterations in the placenta and gut. |
2020-06-17 |
2023-08-13 |
Not clear |
| Amy P Ross, Katharine E McCann, Tony E Larkin, Zhimin Song, Zachary A Grieb, Kim L Huhman, H Elliott Alber. Sex-dependent effects of social isolation on the regulation of arginine-vasopressin (AVP) V1a, oxytocin (OT) and serotonin (5HT) 1a receptor binding and aggression. Hormones and behavior. vol 116. 2020-04-14. PMID:31449813. |
sex-dependent effects of social isolation on the regulation of arginine-vasopressin (avp) v1a, oxytocin (ot) and serotonin (5ht) 1a receptor binding and aggression. |
2020-04-14 |
2023-08-13 |
Not clear |
| Amy P Ross, Katharine E McCann, Tony E Larkin, Zhimin Song, Zachary A Grieb, Kim L Huhman, H Elliott Alber. Sex-dependent effects of social isolation on the regulation of arginine-vasopressin (AVP) V1a, oxytocin (OT) and serotonin (5HT) 1a receptor binding and aggression. Hormones and behavior. vol 116. 2020-04-14. PMID:31449813. |
more specifically, we examined the effects of social isolation on vasopressin (avp) v1a, oxytocin (ot) and serotonin (5-ht)1a receptor binding within the neural circuit controlling social behavior. |
2020-04-14 |
2023-08-13 |
Not clear |
| Vincenzo Paolo Senese, Atiqah Azhari, Kazuyuki Shinohara, Hirokazu Doi, Paola Venuti, Marc H Bornstein, Gianluca Esposit. Implicit associations to infant cry: Genetics and early care experiences influence caregiving propensities. Hormones and behavior. vol 108. 2020-01-22. PMID:30592969. |
employing a gene × environment (g × e) approach, this study investigated the interaction of genetic polymorphisms of the serotonin transporter gene (5-httlpr) and oxytocin receptor genes (oxtr; rs53576, rs2254298) with early parental care experiences in influencing adults' implicit associations to infant cry. |
2020-01-22 |
2023-08-13 |
Not clear |
| C J Carter, R A Blizar. Autism genes are selectively targeted by environmental pollutants including pesticides, heavy metals, bisphenol A, phthalates and many others in food, cosmetics or household products. Neurochemistry international. 2019-11-20. PMID:27984170. |
many suspect compounds identified in epidemiology, including tetrachlorodibenzodioxin, pesticides, particulate matter, benzo(a)pyrene, heavy metals, valproate, acetaminophen, ssri's, cocaine, bisphenol a, phthalates, polyhalogenated biphenyls, flame retardants, diesel constituents, terbutaline and oxytocin, inter alia showed a significant degree of bias towards asg's, as did relevant endogenous agents (retinoids, sex steroids, thyroxine, melatonin, folate, dopamine, serotonin). |
2019-11-20 |
2023-08-13 |
Not clear |
| Kimbra A Edwards, Amanda M K Madden, Susan L Zu. Serotonin receptor regulation as a potential mechanism for sexually dimorphic oxytocin dysregulation in a model of Autism. Brain research. vol 1701. 2019-11-04. PMID:30040918. |
perinatal administration of serotonin (5ht) agonist 5-methoxytryptamine (5mt) induces developmental hyperserotonemia (dhs; elevated blood serotonin) and produces behavioral and neurochemical changes in rats relevant to autism spectrum disorder (asd), such as oxytocin dysregulation. |
2019-11-04 |
2023-08-13 |
rat |
| Tao-Fang Xi, Dan-Ni Li, Yu-Yian Li, Ying Qin, Hai-Hong Wang, Ning-Ning Song, Qiong Zhang, Yu-Qiang Ding, Xuan-Zheng Shi, Dong-Ping Xi. Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway. Biochemical and biophysical research communications. vol 508. issue 3. 2019-09-17. PMID:30545636. |
central 5-hydroxytryptamine (5-ht) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway. |
2019-09-17 |
2023-08-13 |
mouse |
| Tao-Fang Xi, Dan-Ni Li, Yu-Yian Li, Ying Qin, Hai-Hong Wang, Ning-Ning Song, Qiong Zhang, Yu-Qiang Ding, Xuan-Zheng Shi, Dong-Ping Xi. Central 5-hydroxytryptamine (5-HT) mediates colonic motility by hypothalamus oxytocin-colonic oxytocin receptor pathway. Biochemical and biophysical research communications. vol 508. issue 3. 2019-09-17. PMID:30545636. |
in this study, we used central 5-ht knockout (ko) mice to investigate whether brain-derived 5-ht mediates colonic motility, and if so, whether it involves oxytocin (ot) production in the hypothalamus and ot receptor in the colon. |
2019-09-17 |
2023-08-13 |
mouse |
| Peter Goo. Evidence the U.S. autism epidemic initiated by acetaminophen (Tylenol) is aggravated by oral antibiotic amoxicillin/clavulanate (Augmentin) and now exponentially by herbicide glyphosate (Roundup). Clinical nutrition ESPEN. vol 23. 2019-05-31. PMID:29460795. |
placental/postnatal estrogens dehydrate/mature brain myelin sheaths, mature corpus callosum and left hemisphere preferentially, dilate brain blood vessels, and elevate brain serotonin and oxytocin. |
2019-05-31 |
2023-08-13 |
Not clear |
| Tamar L Gur, Aditi Vadodkar Palkar, Therese Rajasekera, Jacob Allen, Anzela Niraula, Jonathan Godbout, Michael T Baile. Prenatal stress disrupts social behavior, cortical neurobiology and commensal microbes in adult male offspring. Behavioural brain research. vol 359. 2019-04-03. PMID:29949734. |
male offspring exposed to prenatal stress also had neuroinflammation, decreased oxytocin receptor, and decreased serotonin metabolism in their cortex in adulthood, which are linked to decreased social behavior. |
2019-04-03 |
2023-08-13 |
mouse |