| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gustav Mårtensson, Claes Håkansson, Joana B Pereira, Sebastian Palmqvist, Oskar Hansson, Danielle van Westen, Eric Westma. Medial temporal atrophy in preclinical dementia: Visual and automated assessment during six year follow-up. NeuroImage. Clinical. vol 27. 2021-06-25. PMID:32580125. |
we found that mtl atrophy rates increased with csf biomarker abnormality, used to define preclinical stages of alzheimer's disease. |
2021-06-25 |
2023-08-13 |
Not clear |
| Robin de Flores, Laura E M Wisse, Sandhitsu R Das, Long Xie, Corey T McMillan, John Q Trojanowski, John L Robinson, Murray Grossman, Edward Lee, David J Irwin, Paul A Yushkevich, David A Wol. Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue 6. 2021-06-03. PMID:32323446. |
it is unclear how different proteinopathies (tau, transactive response dna-binding protein 43 [tdp-43], amyloid β [aβ], and α-synuclein) contribute to atrophy within medial temporal lobe (mtl) subregions in alzheimer's disease (ad). |
2021-06-03 |
2023-08-13 |
Not clear |
| Masashi Kameyama, Kenji Ishibashi, Jun Toyohara, Kei Wagatsuma, Yumi Umeda-Kameyama, Keigo Shimoji, Kazutomi Kanemaru, Shigeo Murayama, Sumito Ogawa, Aya M Tokumaru, Kenji Ishi. Voxel-based morphometry focusing on medial temporal lobe structures has a limited capability to detect amyloid β, an Alzheimer's disease pathology. Aging. vol 12. issue 19. 2020-12-19. PMID:33024054. |
voxel-based morphometry (vbm) analysis of nuclear magnetic resonance imaging (mri) data allows the identification of medial temporal lobe (mtl) atrophy and is widely used to assist the diagnosis of alzheimer's disease (ad). |
2020-12-19 |
2023-08-13 |
Not clear |
| Naiara Aguirre, Víctor Costumero, Lidón Marin-Marin, Joaquín Escudero, Vicente Belloch, María Antonia Parcet, César Ávil. Activity in Memory Brain Networks During Encoding Differentiates Mild Cognitive Impairment Converters from Non-Converters. Journal of Alzheimer's disease : JAD. vol 71. issue 3. 2020-11-05. PMID:31476154. |
alzheimer's disease (ad) has been associated with memory impairment due to alterations in the medial temporal lobe (mtl) and the precuneus. |
2020-11-05 |
2023-08-13 |
human |
| Xiangyu Ma, Zhaoxia Li, Bin Jing, Han Liu, Dan Li, Haiyun L. Identify the Atrophy of Alzheimer's Disease, Mild Cognitive Impairment and Normal Aging Using Morphometric MRI Analysis. Frontiers in aging neuroscience. vol 8. 2020-10-01. PMID:27803665. |
quantitatively assessing the medial temporal lobe (mtl) structures atrophy is vital for early diagnosis of alzheimer's disease (ad) and accurately tracking of the disease progression. |
2020-10-01 |
2023-08-13 |
Not clear |
| Val J Lowe, Tyler J Bruinsma, Hoon-Ki Min, Emily S Lundt, Ping Fang, Matthew L Senjem, Bradley F Boeve, Keith A Josephs, Mukesh K Pandey, Melissa E Murray, Kejal Kantarci, David T Jones, Christopher G Schwarz, David S Knopman, Ronald C Petersen, Clifford R Jac. Elevated medial temporal lobe and pervasive brain tau-PET signal in normal participants. Alzheimer's & dementia (Amsterdam, Netherlands). vol 10. 2020-10-01. PMID:29780865. |
medial temporal lobe (mtl) uptake on tau-positron emission tomography (pet) is seen not only in alzheimer's disease (ad) dementia but also in the aging population. |
2020-10-01 |
2023-08-13 |
human |
| Lorenzo Pasquini, Farzaneh Rahmani, Somayeh Maleki-Balajoo, Renaud La Joie, Mojtaba Zarei, Christian Sorg, Alexander Drzezga, Masoud Tahmasia. Medial Temporal Lobe Disconnection and Hyperexcitability Across Alzheimer's Disease Stages. Journal of Alzheimer's disease reports. vol 3. issue 1. 2020-10-01. PMID:31259307. |
the posteromedial cortex (pmc) and medial temporal lobes (mtl) are two brain regions particularly vulnerable in alzheimer's disease (ad). |
2020-10-01 |
2023-08-13 |
Not clear |
| b' Mindaugas Baranauskas, Rytis Jurkonis, Ar\\xc5\\xabnas Luko\\xc5\\xa1evi\\xc4\\x8dius, Monika Mak\\xc5\\xabnait\\xc4\\x97, Vaidas Matijo\\xc5\\xa1aitis, Rymant\\xc4\\x97 Gleiznien\\xc4\\x97, Daiva Rastenyt\\xc4\\x9. Ultrasonic Assessment of the Medial Temporal Lobe Tissue Displacements in Alzheimer\'s Disease. Diagnostics (Basel, Switzerland). vol 10. issue 7. 2020-09-28. PMID:32635379.' |
we aim to estimate brain tissue displacements in the medial temporal lobe (mtl) using backscattered ultrasound radiofrequency (us rf) signals, and to assess the diagnostic ability of brain tissue displacement parameters for the differentiation of patients with alzheimer's disease (ad) from healthy controls (hc). |
2020-09-28 |
2023-08-13 |
Not clear |
| Daiva Rastenyte, Vaidas Matijosaitis, Ovidijus Laucius, Rymante Gleizniene, Simonas Jesmanas, Kristina Jurenien. Diagnostic Ability of Structural Transcranial Sonography in Patients with Alzheimer's Disease. Diagnostics (Basel, Switzerland). vol 10. issue 7. 2020-09-28. PMID:32664455. |
the aim of this study was to assess the diagnostic ability of transcranial sonography (tcs) for the evaluation of the medial temporal lobe (mtl) in alzheimer's disease (ad). |
2020-09-28 |
2023-08-13 |
human |
| Kimberley Yuen, Neda Rashidi-Ranjbar, Nicolaas Paul L G Verhoeff, Sanjeev Kumar, Damien Gallagher, Alastair J Flint, Nathan Herrmann, Bruce G Pollock, Benoit H Mulsant, Tarek K Rajji, Aristotle N Voineskos, Corinne E Fischer, Linda Ma. Association between Sleep Disturbances and Medial Temporal Lobe Volume in Older Adults with Mild Cognitive Impairment Free of Lifetime History of Depression. Journal of Alzheimer's disease : JAD. vol 69. issue 2. 2020-09-10. PMID:31104028. |
previous studies examining the link between neuropsychiatric symptoms (nps) and biomarkers of alzheimer's disease (ad) may be confounded by remitted or past history of psychiatric illness, which in itself is associated with ad biomarkers such as reduced medial temporal lobe (mtl) volume. |
2020-09-10 |
2023-08-13 |
Not clear |
| Domilė Tautvydaitė, Aurélie L Manuel, Louis Nahum, Alexandra Adam-Darqué, Radek Ptak, Armin Schnide. Absence of an early hippocampal encoding signal after medial temporal lesions: No consequence for the spacing effect. Hippocampus. vol 29. issue 7. 2020-06-01. PMID:30421476. |
we suggest that the early frontal signal at 200-300 ms after immediate picture repetition may serve as a direct biomarker of mtl integrity that may be useful in the early stages of diseases like alzheimer's. |
2020-06-01 |
2023-08-13 |
Not clear |
| Long Xie, Laura E M Wisse, John Pluta, Robin de Flores, Virgine Piskin, Jose V Manjón, Hongzhi Wang, Sandhitsu R Das, Song-Lin Ding, David A Wolk, Paul A Yushkevic. Automated segmentation of medial temporal lobe subregions on in vivo T1-weighted MRI in early stages of Alzheimer's disease. Human brain mapping. vol 40. issue 12. 2020-04-02. PMID:31034738. |
medial temporal lobe (mtl) substructures are the earliest regions affected by neurofibrillary tangle pathology-and thus are promising biomarkers for alzheimer's disease (ad). |
2020-04-02 |
2023-08-13 |
human |
| Theresa M Harrison, Anne Maass, Jenna N Adams, Richard Du, Suzanne L Baker, William J Jagus. Tau deposition is associated with functional isolation of the hippocampus in aging. Nature communications. vol 10. issue 1. 2020-02-11. PMID:31653847. |
the tau protein aggregates in aging and alzheimer disease and may lead to memory loss through disruption of medial temporal lobe (mtl)-dependent memory systems. |
2020-02-11 |
2023-08-13 |
Not clear |
| Laura E Korthauer, Elizabeth Awe, Marijam Frahmand, Ira Driscol. Genetic Risk for Age-Related Cognitive Impairment Does Not Predict Cognitive Performance in Middle Age. Journal of Alzheimer's disease : JAD. vol 64. issue 2. 2019-07-15. PMID:29865048. |
alzheimer's disease (ad) is characterized by memory loss and executive dysfunction, which correspond to structural changes to the medial temporal lobes (mtl) and prefrontal cortex (pfc), respectively. |
2019-07-15 |
2023-08-13 |
human |
| Jiu Chen, Xujun Duan, Hao Shu, Zan Wang, Zhiliang Long, Duan Liu, Wenxiang Liao, Yongmei Shi, Huafu Chen, Zhijun Zhan. Differential contributions of subregions of medial temporal lobe to memory system in amnestic mild cognitive impairment: insights from fMRI study. Scientific reports. vol 6. 2018-04-02. PMID:27184985. |
altered function of the medial temporal lobe (mtl) is a valuable indicator of conversion from amnestic mild cognitive impairment (amci) to alzheimer's disease. |
2018-04-02 |
2023-08-13 |
Not clear |
| Alexandre Bejanin, Béatrice Desgranges, Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache, Gaël Chétela. Distinct white matter injury associated with medial temporal lobe atrophy in Alzheimer's versus semantic dementia. Human brain mapping. vol 38. issue 4. 2018-01-29. PMID:27981671. |
this study aims at further understanding the distinct vulnerability of brain networks in alzheimer's disease (ad) versus semantic dementia (sd) investigating the white matter injury associated with medial temporal lobe (mtl) atrophy in both conditions. |
2018-01-29 |
2023-08-13 |
Not clear |
| Eske Christiane Gertje, John Pluta, Sandhitsu Das, Lauren Mancuso, Dasha Kliot, Paul Yushkevich, David Wol. Clinical Application of Automatic Segmentation of Medial Temporal Lobe Subregions in Prodromal and Dementia-Level Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 3. 2018-01-26. PMID:27567809. |
volumetry of medial temporal lobe (mtl) structures to diagnose alzheimer's disease (ad) in its earliest symptomatic stage could be of great importance for interventions or disease modifying pharmacotherapy. |
2018-01-26 |
2023-08-13 |
Not clear |
| Melissa A Lancaster, Michael Seidenberg, J Carson Smith, Kristy A Nielson, John L Woodard, Sally Durgerian, Stephen M Ra. Diffusion Tensor Imaging Predictors of Episodic Memory Decline in Healthy Elders at Genetic Risk for Alzheimer's Disease. Journal of the International Neuropsychological Society : JINS. vol 22. issue 10. 2018-01-19. PMID:27903333. |
the current study investigated the ability of diffusion tensor imaging (dti) in mtl wm tracts to predict 3-year changes in em performance in healthy elders at disproportionately higher genetic risk for alzheimer's disease (ad). |
2018-01-19 |
2023-08-13 |
Not clear |
| Ashley Swanson, A A Willett. Neuronal Pentraxin 2 predicts medial temporal atrophy and memory decline across the Alzheimer's disease spectrum. Brain, behavior, and immunity. vol 58. 2018-01-17. PMID:27444967. |
chronic neuroinflammation is thought to potentiate medial temporal lobe (mtl) atrophy and memory decline in alzheimer's disease (ad). |
2018-01-17 |
2023-08-13 |
Not clear |
| Rosanna K Olsen, Lok-Kin Yeung, Alix Noly-Gandon, Maria C D'Angelo, Arber Kacollja, Victoria M Smith, Jennifer D Ryan, Morgan D Barens. Human anterolateral entorhinal cortex volumes are associated with cognitive decline in aging prior to clinical diagnosis. Neurobiology of aging. vol 57. 2018-01-03. PMID:28578804. |
we investigated whether older adults without subjective memory complaints, but who present with cognitive decline in the laboratory, demonstrate atrophy in medial temporal lobe (mtl) subregions associated with alzheimer's disease. |
2018-01-03 |
2023-08-13 |
human |