| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B R Pearce, A M Palmer, D M Bowen, G K Wilcock, M M Esiri, A N Daviso. Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease. Neurochemical pathology. vol 2. issue 4. 1985-10-08. PMID:6085697. |
neurotransmitter dysfunction and atrophy of the caudate nucleus in alzheimer's disease. |
1985-10-08 |
2023-08-12 |
Not clear |
| B R Pearce, A M Palmer, D M Bowen, G K Wilcock, M M Esiri, A N Daviso. Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease. Neurochemical pathology. vol 2. issue 4. 1985-10-08. PMID:6085697. |
the caudate nucleus from examples of alzheimer's disease (mean age 68, range 51-77 yr) had a mean wet weight and total protein content that were significantly lower than control. |
1985-10-08 |
2023-08-12 |
Not clear |
| J O Rinne, K Laakso, P Lönnberg, P Mölsä, L Paljärvi, J K Rinne, E Säkö, U K Rinn. Brain muscarinic receptors in senile dementia. Brain research. vol 336. issue 1. 1985-08-20. PMID:4005573. |
the binding of [3h]qnb was significantly decreased in the hippocampus, amygdala and nucleus accumbens in patients with alzheimer's disease (ad) and with combined type of dementia (cd), whereas in patients with multi-infarct dementia (mid) the binding was not significantly decreased in the limbic areas but only in the caudate nucleus. |
1985-08-20 |
2023-08-11 |
Not clear |
| N M Borthwick, A Gordon, C M Yate. Reductions in soluble brain proteins in older subjects with Down's syndrome. Journal of the neurological sciences. vol 68. issue 2-3. 1985-07-29. PMID:3159852. |
in older down's syndrome cases, reductions in tubulin and 5 other proteins were observed in cortex which had the neuropathology of alzheimer's disease but not in caudate nucleus. |
1985-07-29 |
2023-08-11 |
human |
| D L Sparks, J T Slevi. Determination of tyrosine, tryptophan and their metabolic derivatives by liquid chromatography-electrochemical detection: application to post mortem samples from patients with Parkinson's and Alzheimer's disease. Life sciences. vol 36. issue 5. 1985-03-18. PMID:3968972. |
the levels of neurochemicals in the caudate and putamen of patients with alzheimer's disease (sdat) were also variably decreased; loss of ne was seen only in putamen and losses of da, hva and 5-ht were uniform across both caudate and putamen. |
1985-03-18 |
2023-08-11 |
human |
| E Perdahl, R Adolfsson, I Alafuzoff, K A Albert, E J Nestler, P Greengard, B Winbla. Synapsin I (protein I) in different brain regions in senile dementia of Alzheimer type and in multi-infarct dementia. Journal of neural transmission. vol 60. issue 2. 1984-12-12. PMID:6436437. |
synapsin i (protein i), a neuron-specific phosphoprotein enriched in presynaptic nerve terminals, has been used as a quantitative marker for the density of nerve terminals in five brain regions (caudate nucleus, cingulate gyrus, hippocampus, mesencephalon and putamen) from patients who had suffered from alzheimer disease/senile dementia of alzheimer type (ad/sdat), from patients with multi-infarct dementia (mid), and from age-matched controls. |
1984-12-12 |
2023-08-12 |
Not clear |
| B R Pearce, D M Bowe. [3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia. Brain research. vol 310. issue 2. 1984-12-10. PMID:6488028. |
the binding of [3h]kainic acid to caudate nucleus membranes prepared from brains of examples of alzheimer's dementia and controls has been determined. |
1984-12-10 |
2023-08-12 |
Not clear |
| D E Kuh. Imaging local brain function with emission computed tomography. Radiology. vol 150. issue 3. 1984-03-23. PMID:6607481. |
the fdg scan appears normal in the depressed patient, studded with multiple metabolic defects in patients with multiple infarct dementia, and in the patients with alzheimer disease, metabolism is particularly reduced in the parietal cortex, but only slightly reduced in the caudate and thalamus. |
1984-03-23 |
2023-08-12 |
human |
| S Sorbi, E D Bird, J P Blas. Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain. Annals of neurology. vol 13. issue 1. 1983-04-07. PMID:6219611. |
the activity of the pyruvate dehydrogenase complex (pdhc) was reduced in affected areas of brain from patients with huntington disease (caudate, putamen) and alzheimer disease (frontal cortex) where choline acetyltransferase (cat) activity was low. |
1983-04-07 |
2023-08-12 |
cat |
| A Arregui, E K Perry, M Rossor, B E Tomlinso. Angiotensin converting enzyme in Alzheimer's disease increased activity in caudate nucleus and cortical areas. Journal of neurochemistry. vol 38. issue 5. 1982-05-27. PMID:6278093. |
angiotensin converting enzyme in alzheimer's disease increased activity in caudate nucleus and cortical areas. |
1982-05-27 |
2023-08-12 |
Not clear |
| A Arregui, E K Perry, M Rossor, B E Tomlinso. Angiotensin converting enzyme in Alzheimer's disease increased activity in caudate nucleus and cortical areas. Journal of neurochemistry. vol 38. issue 5. 1982-05-27. PMID:6278093. |
enzyme activity was found to be elevated by 44% and 41% in the medial hippocampus and parahippocampal gyrus, respectively, and by 27% and 29% in the frontal cortex (area 10 of brodman) and caudate nucleus, respectively, in alzheimer's disease patients. |
1982-05-27 |
2023-08-12 |
Not clear |