| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kyungha Shin, Yeseul Cha, Kwang Sei Kim, Ehn-Kyoung Choi, Youngjin Choi, Haiyu Guo, Young-Hwan Ban, Jong-Choon Kim, Dongsun Park, Yun-Bae Ki. Human Neural Stem Cells Overexpressing Choline Acetyltransferase Restore Unconditioned Fear in Rats with Amygdala Injury. Behavioural neurology. vol 2016. 2016-12-13. PMID:27087745. |
we previously demonstrated that f3.chat human neural stem cells (nscs) overexpressing choline acetyltransferase (chat) improve cognitive function of alzheimer's disease model rats with hippocampal or cholinergic nerve injuries by increasing acetylcholine (ach) level. |
2016-12-13 |
2023-08-13 |
human |
| Maite Mendioroz, Naiara Celarain, Miren Altuna, Javier Sánchez-Ruiz de Gordoa, María Victoria Zelaya, Miren Roldán, Idoya Rubio, Rosa Larumbe, María Elena Erro, Iván Méndez, Carmen Echávarr. CRTC1 gene is differentially methylated in the human hippocampus in Alzheimer's disease. Alzheimer's research & therapy. vol 8. issue 1. 2016-12-13. PMID:27094739. |
crtc1 gene is differentially methylated in the human hippocampus in alzheimer's disease. |
2016-12-13 |
2023-08-13 |
human |
| Eleonora Gatta, Tony Lefebvre, Silvana Gaetani, Marc dos Santos, Jordan Marrocco, Anne-Marie Mir, Tommaso Cassano, Stefania Maccari, Ferdinando Nicoletti, Jérôme Mairess. Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease. Pharmacological research. vol 105. 2016-11-11. PMID:26816085. |
evidence for an imbalance between tau o-glcnacylation and phosphorylation in the hippocampus of a mouse model of alzheimer's disease. |
2016-11-11 |
2023-08-13 |
mouse |
| Sinéad M Ryan, Yvonne M Nola. Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate? Neuroscience and biobehavioral reviews. vol 61. 2016-11-09. PMID:26695382. |
dysregulation of hippocampal neurogenesis has been shown to be an important mechanism underlying the cognitive impairment associated with normal aging, as well as the cognitive deficits evident in preclinical models of alzheimer's disease and other neurodegenerative diseases. |
2016-11-09 |
2023-08-13 |
Not clear |
| Avi Ohry, Octavian Bud. Teofil Simchowicz (1879-1957): the scientist who coined senile plaques in neuropathology. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 56. issue 4. 2016-11-07. PMID:26743308. |
simchowicz coined the terms senile plaques, senile index, and granulovacuolar degeneration - discovered in the hippocampus in patients with alzheimer's disease, and described the nasomental reflex. |
2016-11-07 |
2023-08-13 |
Not clear |
| Jun Ku Chung, Eric Plitman, Shinichiro Nakajima, M Mallar Chakravarty, Fernando Caravaggio, Hiroyoshi Takeuchi, Philip Gerretsen, Yusuke Iwata, Raihaan Patel, Benoit H Mulsant, Ariel Graff-Guerrer. Depressive Symptoms and Small Hippocampal Volume Accelerate the Progression to Dementia from Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 49. issue 3. 2016-11-01. PMID:26519442. |
using data from alzheimer's disease neuroimaging initiative, we examined 2-year follow-up data from 38 dep+amci patients and 38 matched dep-amci patients and compared their ages of conversion from amci to ad and trajectories of progressive hippocampal volume changes. |
2016-11-01 |
2023-08-13 |
Not clear |
| Stefan Teipel, Michel J Groth. Does posterior cingulate hypometabolism result from disconnection or local pathology across preclinical and clinical stages of Alzheimer's disease? European journal of nuclear medicine and molecular imaging. vol 43. issue 3. 2016-11-01. PMID:26555082. |
posterior cingulate cortex (pcc) hypometabolism as measured by fdg pet is an indicator of alzheimer's disease (ad) in prodromal stages, such as in mild cognitive impairment (mci), and has been found to be closely associated with hippocampus atrophy in ad dementia. |
2016-11-01 |
2023-08-13 |
Not clear |
| Hongyan Li, Tingguo Kang, Bin Qi, Liang Kong, Yanan Jiao, Yang Cao, Jianghua Zhang, Jingxian Yan. Neuroprotective effects of ginseng protein on PI3K/Akt signaling pathway in the hippocampus of D-galactose/AlCl3 inducing rats model of Alzheimer's disease. Journal of ethnopharmacology. vol 179. 2016-10-31. PMID:26721223. |
neuroprotective effects of ginseng protein on pi3k/akt signaling pathway in the hippocampus of d-galactose/alcl3 inducing rats model of alzheimer's disease. |
2016-10-31 |
2023-08-13 |
rat |
| Babak A Ardekani, Antonio Convit, Alvin H Bachma. Analysis of the MIRIAD Data Shows Sex Differences in Hippocampal Atrophy Progression. Journal of Alzheimer's disease : JAD. vol 50. issue 3. 2016-10-31. PMID:26836168. |
hippocampus (hc) atrophy is a hallmark of early alzheimer's disease (ad). |
2016-10-31 |
2023-08-13 |
Not clear |
| Lauge Sørensen, Christian Igel, Naja Liv Hansen, Merete Osler, Martin Lauritzen, Egill Rostrup, Mads Nielse. Early detection of Alzheimer's disease using MRI hippocampal texture. Human brain mapping. vol 37. issue 3. 2016-10-28. PMID:26686837. |
early detection of alzheimer's disease using mri hippocampal texture. |
2016-10-28 |
2023-08-13 |
Not clear |
| Lauge Sørensen, Christian Igel, Naja Liv Hansen, Merete Osler, Martin Lauritzen, Egill Rostrup, Mads Nielse. Early detection of Alzheimer's disease using MRI hippocampal texture. Human brain mapping. vol 37. issue 3. 2016-10-28. PMID:26686837. |
cognitive impairment in patients with alzheimer's disease (ad) is associated with reduction in hippocampal volume in magnetic resonance imaging (mri). |
2016-10-28 |
2023-08-13 |
Not clear |
| Xuting Shen, Jianmin Chen, Jiali Li, Julia Kofler, Karl Herru. Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling. eNeuro. vol 3. issue 1. 2016-10-27. PMID:27022623. |
alzheimer's disease (ad), by contrast, is a largely sporadic neurodegenerative disorder that rarely strikes before the 7th decade of life with primary neuronal losses in hippocampus, frontal cortex, and certain subcortical nuclei. |
2016-10-27 |
2023-08-13 |
mouse |
| Kathlyn J Gan, Michael A Silverma. Imaging organelle transport in primary hippocampal neurons treated with amyloid-β oligomers. Methods in cell biology. vol 131. 2016-10-19. PMID:26794527. |
we describe a strategy for fluorescent imaging of organelle transport in primary hippocampal neurons treated with amyloid-β (aβ) peptides that cause alzheimer's disease (ad). |
2016-10-19 |
2023-08-13 |
Not clear |
| Doaa M Samy, Cherine A Ismail, Rasha A Nassra, Teshreen M Zeitoun, Azhar M Nomai. Downstream modulation of extrinsic apoptotic pathway in streptozotocin-induced Alzheimer's dementia in rats: Erythropoietin versus curcumin. European journal of pharmacology. vol 770. 2016-10-14. PMID:26638997. |
in conclusion, icv-streptozotocin-induced alzheimer's dementia activates hippocampal fas ligand-mediated apoptosis, which could be reduced by erythropoietin and/or curcumin treatment. |
2016-10-14 |
2023-08-13 |
rat |
| Roya Behrouzi, Xiawei Liu, Dongyue Wu, Andrew C Robinson, Sayuri Tanaguchi-Watanabe, Sara Rollinson, Jing Shi, Jinzhou Tian, Hisham H M Hamdalla, John Ealing, Anna Richardson, Matthew Jones, Stuart Pickering-Brown, Yvonne S Davidson, Michael J Strong, Masato Hasegawa, Julie S Snowden, David M A Man. Pathological tau deposition in Motor Neurone Disease and frontotemporal lobar degeneration associated with TDP-43 proteinopathy. Acta neuropathologica communications. vol 4. 2016-10-14. PMID:27036121. |
in most instances, this bore the histological characteristics of an alzheimer's disease process involving entorhinal cortex, hippocampus, temporal cortex, frontal cortex and occipital cortex in decreasing frequency, accompanied by a deposition of aβ up to thal phase 3, though 2 patients with mnd, and 1 with ftd did show tau pathology beyond braak stage iii. |
2016-10-14 |
2023-08-13 |
Not clear |
| Efrat Kliper, Einor Ben Assayag, Amos D Korczyn, Eitan Auriel, Ludmila Shopin, Hen Hallevi, Shani Shenhar-Tsarfaty, Anat Mike, Moran Artzi, Ilana Klovatch, Natan M Bornstein, Dafna Ben Basha. Cognitive state following mild stroke: A matter of hippocampal mean diffusivity. Hippocampus. vol 26. issue 2. 2016-10-13. PMID:26222988. |
the hippocampus is known to play a vital role in learning and memory and was demonstrated as an early imaging marker for alzheimer's disease (ad). |
2016-10-13 |
2023-08-13 |
Not clear |
| Elijah Mak, Li Su, Guy B Williams, Rosie Watson, Michael Firbank, Andrew Blamire, John O'Brie. Differential Atrophy of Hippocampal Subfields: A Comparative Study of Dementia with Lewy Bodies and Alzheimer Disease. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 24. issue 2. 2016-10-13. PMID:26324541. |
differential atrophy of hippocampal subfields: a comparative study of dementia with lewy bodies and alzheimer disease. |
2016-10-13 |
2023-08-13 |
human |
| Q Zeng, M Zheng, T Zhang, G H. Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer's disease. Neuroscience. vol 314. 2016-10-13. PMID:26639620. |
hippocampal neurogenesis in the app/ps1/nestin-gfp triple transgenic mouse model of alzheimer's disease. |
2016-10-13 |
2023-08-13 |
mouse |
| Theresa M Harrison, Alison C Burggren, Gary W Small, Susan Y Bookheime. Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease. Human brain mapping. vol 37. issue 1. 2016-10-11. PMID:26503161. |
altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for alzheimer's disease. |
2016-10-11 |
2023-08-13 |
Not clear |
| Theresa M Harrison, Alison C Burggren, Gary W Small, Susan Y Bookheime. Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease. Human brain mapping. vol 37. issue 1. 2016-10-11. PMID:26503161. |
the hippocampal complex is affected early in alzheimer's disease (ad). |
2016-10-11 |
2023-08-13 |
Not clear |