| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vanessa A Guzman, Owen T Carmichael, Christopher Schwarz, Giuseppe Tosto, Molly E Zimmerman, Adam M Brickma. White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 5 Suppl. 2014-05-28. PMID:23375566. |
current hypothetical models of alzheimer's disease (ad) pathogenesis emphasize the role of β-amyloid (aβ), tau deposition, and neurodegenerative changes in the mesial temporal lobe, particularly the entorhinal cortex and hippocampus. |
2014-05-28 |
2023-08-12 |
Not clear |
| Vanessa A Guzman, Owen T Carmichael, Christopher Schwarz, Giuseppe Tosto, Molly E Zimmerman, Adam M Brickma. White matter hyperintensities and amyloid are independently associated with entorhinal cortex volume among individuals with mild cognitive impairment. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 5 Suppl. 2014-05-28. PMID:23375566. |
we used data from the alzheimer's disease neuroimaging initiative (adni) to (1) confirm whether entorhinal cortex and hippocampal volume are associated with memory among individuals with amnestic mild cognitive impairment (mci) who are at risk for ad; and (2) determine whether regional white matter hyperintensity (wmh) volume, a radiological marker of small-vessel cerebrovascular disease, is associated with entorhinal cortex and hippocampal volume independent of putative ad biomarkers in this group. |
2014-05-28 |
2023-08-12 |
Not clear |
| Egidio D'Angelo, Paolo Mazzarell. MRI observation of hippocampal degeneration in Alzheimer's disease: a forgotten case. Functional neurology. vol 28. issue 3. 2014-05-28. PMID:24139660. |
mri observation of hippocampal degeneration in alzheimer's disease: a forgotten case. |
2014-05-28 |
2023-08-12 |
Not clear |
| Egidio D'Angelo, Paolo Mazzarell. MRI observation of hippocampal degeneration in Alzheimer's disease: a forgotten case. Functional neurology. vol 28. issue 3. 2014-05-28. PMID:24139660. |
at the beginning of the 1990s, as part of work being done for a master's degree thesis in physics, an important observation of hippocampal degeneration in alzheimer's disease was made in pavia. |
2014-05-28 |
2023-08-12 |
Not clear |
| J B Pereira, L Cavallin, G Spulber, C Aguilar, P Mecocci, B Vellas, M Tsolaki, I Kłoszewska, H Soininen, C Spenger, D Aarsland, S Lovestone, A Simmons, L-O Wahlund, E Westma. Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs. Journal of internal medicine. vol 275. issue 3. 2014-05-26. PMID:24118559. |
visual assessment of medial temporal lobe atrophy (mta; range 0-4, from no atrophy to increasing atrophy of the choroid fissure, temporal horns and hippocampus) is a sensitive radiological marker of alzheimer's disease (ad). |
2014-05-26 |
2023-08-12 |
Not clear |
| Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pélerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656258. |
intrinsic connectivity identifies the hippocampus as a main crossroad between alzheimer's and semantic dementia-targeted networks. |
2014-05-21 |
2023-08-12 |
Not clear |
| Renaud La Joie, Brigitte Landeau, Audrey Perrotin, Alexandre Bejanin, Stéphanie Egret, Alice Pélerin, Florence Mézenge, Serge Belliard, Vincent de La Sayette, Francis Eustache, Béatrice Desgranges, Gaël Chétela. Intrinsic connectivity identifies the hippocampus as a main crossroad between Alzheimer's and semantic dementia-targeted networks. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656258. |
alzheimer's disease (ad) and semantic dementia (sd) are both characterized by severe atrophy in the hippocampus, a brain region underlying episodic memory; paradoxically, episodic memory is relatively preserved in sd. |
2014-05-21 |
2023-08-12 |
Not clear |
| Lei Li, Liling Yu, Qingxia Kon. Exogenous galanin attenuates spatial memory impairment and decreases hippocampal β-amyloid levels in rat model of Alzheimer's disease. The International journal of neuroscience. vol 123. issue 11. 2014-05-19. PMID:23687905. |
exogenous galanin attenuates spatial memory impairment and decreases hippocampal β-amyloid levels in rat model of alzheimer's disease. |
2014-05-19 |
2023-08-12 |
rat |
| You Yu, Yan Zhan. Desflurane accelerates neuronal cytotoxicity of Aβ by downregulating miR-214. Neuroscience letters. vol 554. 2014-05-16. PMID:24021802. |
since more and more evidence suggests anesthetics serve as a risk factor of alzheimer's disease (ad), we examine the neurotoxicity of a commonly used inhalational anesthetics, desflurane, and its potential toxicity mechanism in primary rat hippocampal neurons. |
2014-05-16 |
2023-08-12 |
rat |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the ca1 subfield of the hippocampus in the triple transgenic model of alzheimer's disease. |
2014-05-15 |
2023-08-12 |
mouse |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
alzheimer's disease (ad) is an irreversible neurodegenerative disease that is characterised by the presence of β-amyloid (aβ) plaques, neurofibrillary tangles (nfts) and synaptic loss specifically in brain regions involved in learning and memory such as the neocortex and the hippocampus. |
2014-05-15 |
2023-08-12 |
mouse |
| Marco Vacante, Gordon K Wilcock, Celeste A de Jage. Computerized adaptation of The Placing Test for early detection of both mild cognitive impairment and Alzheimer's disease. Journal of clinical and experimental neuropsychology. vol 35. issue 8. 2014-05-15. PMID:23985007. |
changes in the hippocampal system have been proposed as a possible marker of incipient alzheimer's disease (ad) at the mild cognitive impairment (mci) stage. |
2014-05-15 |
2023-08-12 |
human |
| Elizabeth Gemmell, Edward Tam, Louise Allan, Roslyn Hall, Ahmad Khundakar, Arthur E Oakley, Alan Thomas, Vincent Deramecourt, Raj N Kalari. Neuron volumes in hippocampal subfields in delayed poststroke and aging-related dementias. Journal of neuropathology and experimental neurology. vol 73. issue 4. 2014-05-12. PMID:24607963. |
hippocampal atrophy is widely recognized in alzheimer disease (ad). |
2014-05-12 |
2023-08-12 |
human |
| Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vigne. Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus. PloS one. vol 8. issue 9. 2014-05-08. PMID:24069328. |
area-specific alterations of synaptic plasticity in the 5xfad mouse model of alzheimer's disease: dissociation between somatosensory cortex and hippocampus. |
2014-05-08 |
2023-08-12 |
mouse |
| Nadine Crouzin, Kevin Baranger, Mélanie Cavalier, Yannick Marchalant, Catherine Cohen-Solal, François S Roman, Michel Khrestchatisky, Santiago Rivera, François Féron, Michel Vigne. Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus. PloS one. vol 8. issue 9. 2014-05-08. PMID:24069328. |
transgenic mouse models of alzheimer's disease (ad) that overproduce the amyloid beta peptide (aβ) have highlighted impairments of hippocampal long-term synaptic plasticity associated with the progression of the disease. |
2014-05-08 |
2023-08-12 |
mouse |
| Reza Rahimian, Gohar Fakhfouri, Shahram Ejtemaei Mehr, Jean-Eric Ghia, Armando A Genazzani, Borna Payandemehr, Ahmad Reza Dehpour, Kazem Mousavizadeh, Dmitry Li. Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats. European journal of clinical investigation. vol 43. issue 10. 2014-05-07. PMID:23937291. |
alzheimer's disease (ad) is a neurodegenerative disorder featured by deposition of beta-amyloid (aβ) plaques in the hippocampus and associated cortices and progressive cognitive decline. |
2014-05-07 |
2023-08-12 |
rat |
| Maël Lebreton, Maxime Bertoux, Claire Boutet, Stéphane Lehericy, Bruno Dubois, Philippe Fossati, Mathias Pessiglion. A critical role for the hippocampus in the valuation of imagined outcomes. PLoS biology. vol 11. issue 10. 2014-05-06. PMID:24167442. |
conversely, patients with hippocampus atrophy due to alzheimer's disease, but not patients with fronto-temporal dementia, were less inclined to favor options that required mental simulation. |
2014-05-06 |
2023-08-12 |
human |
| J Carson Smith, Kristy A Nielson, John L Woodard, Michael Seidenberg, Sally Durgerian, Kathleen E Hazlett, Christina M Figueroa, Cassandra C Kandah, Christina D Kay, Monica A Matthews, Stephen M Ra. Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease. Frontiers in aging neuroscience. vol 6. 2014-05-05. PMID:24795624. |
physical activity reduces hippocampal atrophy in elders at genetic risk for alzheimer's disease. |
2014-05-05 |
2023-08-13 |
human |
| J Carson Smith, Kristy A Nielson, John L Woodard, Michael Seidenberg, Sally Durgerian, Kathleen E Hazlett, Christina M Figueroa, Cassandra C Kandah, Christina D Kay, Monica A Matthews, Stephen M Ra. Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease. Frontiers in aging neuroscience. vol 6. 2014-05-05. PMID:24795624. |
we examined the impact of physical activity (pa) on longitudinal change in hippocampal volume in cognitively intact older adults at varying genetic risk for the sporadic form of alzheimer's disease (ad). |
2014-05-05 |
2023-08-13 |
human |
| K Nho, J J Corneveaux, S Kim, H Lin, S L Risacher, L Shen, S Swaminathan, V K Ramanan, Y Liu, T Foroud, M H Inlow, A L Siniard, R A Reiman, P S Aisen, R C Petersen, R C Green, C R Jack, M W Weiner, C T Baldwin, K Lunetta, L A Farrer, S J Furney, S Lovestone, A Simmons, P Mecocci, B Vellas, M Tsolaki, I Kloszewska, H Soininen, B C McDonald, M R Farlow, B Ghetti, M J Huentelman, A J Sayki. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular psychiatry. vol 18. issue 7. 2014-05-02. PMID:23608917. |
matched unrelated apoe ε3 homozygous male caucasian participants from the alzheimer's disease neuroimaging initiative (adni) were selected at the extremes of the 2-year longitudinal change distribution of hippocampal volume (eight subjects with rapid rates of atrophy and eight with slow/stable rates of atrophy). |
2014-05-02 |
2023-08-12 |
human |