| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allison R Fusilier, Jennifer A Davis, Jodi R Paul, Stefani D Yates, Laura J McMeekin, Lacy K Goode, Mugdha V Mokashi, Natalie Remiszewski, Thomas van Groen, Rita M Cowell, Lori L McMahon, Erik D Roberson, Karen L Gambl. Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in amyloid precursor protein transgenic mice. Neurobiology of disease. vol 158. 2021-10-14. PMID:34333153. |
uncovering disrupted day/night differences in circadian gene regulation, hippocampal physiology, and memory in ad mouse models may provide insight into possible chronotherapeutic strategies to ameliorate alzheimer's disease symptoms or delay pathological onset. |
2021-10-14 |
2023-08-13 |
mouse |
| Longjian Huang, Jiaqi Lan, Jingshu Tang, Yuying Kang, Xinhong Feng, Lei Wu, Ying Pen. L-3-n-Butylphthalide improves synaptic and dendritic spine plasticity and ameliorates neurite pathology in Alzheimer's disease mouse model and cultured hippocampal neurons. Molecular neurobiology. vol 58. issue 3. 2021-10-13. PMID:33146400. |
l-3-n-butylphthalide improves synaptic and dendritic spine plasticity and ameliorates neurite pathology in alzheimer's disease mouse model and cultured hippocampal neurons. |
2021-10-13 |
2023-08-13 |
mouse |
| Richard Armstron. Fluctuations in neurofibrillary tangle density in Alzheimer's disease revealed by Fourier (spectral) analysis. Folia neuropathologica. vol 58. issue 4. 2021-10-13. PMID:33480234. |
significant densities of neurofibrillary tangles (nft) often occur in regions of the cerebral cortex and hippocampus in cases of alzheimer's disease (ad). |
2021-10-13 |
2023-08-13 |
Not clear |
| Sarra Djemil, Claire R Ressel, Mai Abdel-Ghani, Amanda K Schneeweis, Daniel T S Pa. Central Cholinergic Synapse Formation in Optimized Primary Septal-Hippocampal Co-cultures. Cellular and molecular neurobiology. vol 41. issue 8. 2021-10-12. PMID:32860154. |
septal innervation of basal forebrain cholinergic neurons to the hippocampus is critical for normal learning and memory and is severely degenerated in alzheimer's disease. |
2021-10-12 |
2023-08-13 |
rat |
| Aojie Li, Fan Li, Farzaneh Elahifasaee, Manhua Liu, Lichi Zhan. Hippocampal shape and asymmetry analysis by cascaded convolutional neural networks for Alzheimer's disease diagnosis. Brain imaging and behavior. vol 15. issue 5. 2021-10-12. PMID:33398778. |
hippocampal shape and asymmetry analysis by cascaded convolutional neural networks for alzheimer's disease diagnosis. |
2021-10-12 |
2023-08-13 |
human |
| Aojie Li, Fan Li, Farzaneh Elahifasaee, Manhua Liu, Lichi Zhan. Hippocampal shape and asymmetry analysis by cascaded convolutional neural networks for Alzheimer's disease diagnosis. Brain imaging and behavior. vol 15. issue 5. 2021-10-12. PMID:33398778. |
hippocampal atrophy is often considered as one of the important biomarkers for early diagnosis of alzheimer's disease (ad), which is an irreversible neurodegenerative disorder. |
2021-10-12 |
2023-08-13 |
human |
| Hanan Polansky, Benjamin Gora. How an increase in the copy number of HSV-1 during latency can cause Alzheimer's disease: the viral and cellular dynamics according to the microcompetition model. Journal of neurovirology. 2021-10-12. PMID:34635992. |
finally, we show how an increase in the copy number of hsv-1 in neural stem/progenitor cells in the hippocampus during the latent phase can lead to an abnormal quantity and quality of neurogenesis, and the clinical presentation of alzheimer's disease. |
2021-10-12 |
2023-08-13 |
Not clear |
| Erin R Harrell, Chuong Bui, Sharlene D Newma. A Mixed-Effects Model of Associations between Interleukin-6 and Hippocampal Volume. The journals of gerontology. Series A, Biological sciences and medical sciences. 2021-10-12. PMID:34637514. |
mixed-models were employed to examine both within (across time) and between subjects effects of il-6 and hippocampal volume on mmse score among 566 participants from the alzheimer's disease neuroimaging initiative (adni). |
2021-10-12 |
2023-08-13 |
human |
| Michael Axenhus, Bengt Winblad, Lars O Tjernberg, Sophia Schedin-Weis. Huntingtin Levels are Elevated in Hippocampal Post-Mortem Samples of Alzheimer's Disease Brain. Current Alzheimer research. vol 17. issue 9. 2021-10-11. PMID:33272184. |
huntingtin levels are elevated in hippocampal post-mortem samples of alzheimer's disease brain. |
2021-10-11 |
2023-08-13 |
mouse |
| Madeline Uretsky, Laura E Gibbons, Shubhabrata Mukherjee, Emily H Trittschuh, David W Fardo, Patricia A Boyle, C Dirk Keene, Andrew J Saykin, Paul K Crane, Julie A Schneider, Jesse Me. Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes. Alzheimer's & dementia (New York, N. Y.). vol 7. issue 1. 2021-10-11. PMID:34604500. |
alzheimer's disease (ad) neuropathological subtypes (limbic predominant [lpad], hippocampal sparing [hpspad], and typical [tad]), defined by relative neurofibrillary tangle (nft) burden in limbic and cortical regions, have not been studied in prospectively characterized epidemiological cohorts with robust cognitive assessments. |
2021-10-11 |
2023-08-13 |
Not clear |
| Katherine A Koenig, Se-Hong Oh, Melissa R Stasko, Elizabeth C Roth, H Gerry Taylor, Stephen Ruedrich, Z Irene Wang, James B Leverenz, Alberto C S Cost. High resolution structural and functional MRI of the hippocampus in young adults with Down syndrome. Brain communications. vol 3. issue 2. 2021-10-08. PMID:33977271. |
hippocampal dysfunction may also relate to alzheimer's disease-type pathology, which can appear in as early as the first decade of life and becomes universal by age 40. |
2021-10-08 |
2023-08-13 |
Not clear |
| Cory M Dungan, Taylor Valentino, Ivan J Vechetti, Christopher J Zdunek, Michael P Murphy, Ai-Ling Lin, John J McCarthy, Charlotte A Peterso. Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and Aβ Journal of neurophysiology. vol 124. issue 6. 2021-10-05. PMID:33052800. |
exercise-mediated alteration of hippocampal dicer mrna and mirnas is associated with lower bace1 gene expression and aβ changes to cerebral mirna expression have been implicated in the progression of alzheimer's disease (ad), as mirnas that regulate the expression of gene products involved in amyloid beta (aβ) processing, such as bace1, are dysregulated in those that suffer from ad. |
2021-10-05 |
2023-08-13 |
mouse |
| Zhe-Yu Zhang, Chun-Hu Zhang, Jing-Jing Yang, Pan-Pan Xu, Peng-Ji Yi, Mu-Li Hu, Wei-Jun Pen. Genome-wide analysis of hippocampal transfer RNA-derived small RNAs identifies new potential therapeutic targets of Bushen Tiansui formula against Alzheimer's disease. Journal of integrative medicine. vol 19. issue 2. 2021-10-04. PMID:33334712. |
genome-wide analysis of hippocampal transfer rna-derived small rnas identifies new potential therapeutic targets of bushen tiansui formula against alzheimer's disease. |
2021-10-04 |
2023-08-13 |
rat |
| Dalia A Mandour, M A Bendary, Amira E Alseme. Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid "hesperidin". Journal of molecular histology. vol 52. issue 5. 2021-10-04. PMID:34170456. |
histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of alzheimer like-disease with a preferential role of the flavonoid "hesperidin". |
2021-10-04 |
2023-08-13 |
rat |
| Dalia A Mandour, M A Bendary, Amira E Alseme. Histological and imunohistochemical alterations of hippocampus and prefrontal cortex in a rat model of Alzheimer like-disease with a preferential role of the flavonoid "hesperidin". Journal of molecular histology. vol 52. issue 5. 2021-10-04. PMID:34170456. |
alzheimer's disease (ad) is a chronic age-related neurodegenerative disease characterized by degeneration of the central cholinergic neurons, inflammation and oxidative stress in the basal forebrain, prefrontal cortex and hippocampus. |
2021-10-04 |
2023-08-13 |
rat |
| Mohammadmehdi Hadipour, Gholam Hossein Meftahi, Mohammad Reza Afarinesh, Gila Pirzad Jahromi, Boshra Hate. Crocin attenuates the granular cells damages on the dentate gyrus and pyramidal neurons in the CA3 regions of the hippocampus and frontal cortex in the rat model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:32534024. |
crocin attenuates the granular cells damages on the dentate gyrus and pyramidal neurons in the ca3 regions of the hippocampus and frontal cortex in the rat model of alzheimer's disease. |
2021-10-01 |
2023-08-13 |
rat |
| Mohammadmehdi Hadipour, Gholam Hossein Meftahi, Mohammad Reza Afarinesh, Gila Pirzad Jahromi, Boshra Hate. Crocin attenuates the granular cells damages on the dentate gyrus and pyramidal neurons in the CA3 regions of the hippocampus and frontal cortex in the rat model of Alzheimer's disease. Journal of chemical neuroanatomy. vol 113. 2021-10-01. PMID:32534024. |
amyloid β-peptides (aβ) are considered as a major hallmark of alzheimer's disease (ad) that can induce synaptic loss and apoptosis in brain regions, particularly in the cortex and the hippocampus. |
2021-10-01 |
2023-08-13 |
rat |
| Qianqian Li, Junkai Wang, Jianghong Liu, Yumeng Wang, Kuncheng L. Magnetic Resonance Imaging Measurement of Entorhinal Cortex in the Diagnosis and Differential Diagnosis of Mild Cognitive Impairment and Alzheimer's Disease. Brain sciences. vol 11. issue 9. 2021-10-01. PMID:34573151. |
several magnetic resonance imaging studies have shown that the entorhinal cortex (erc) is the first brain area related to pathologic changes in alzheimer's disease (ad), even before atrophy of the hippocampus (hp). |
2021-10-01 |
2023-08-13 |
Not clear |
| Jason H Y Yeung, Thulani H Palpagama, Oliver W G Wood, Clinton Turner, Henry J Waldvogel, Richard L M Faull, Andrea Kwakowsk. EAAT2 Expression in the Hippocampus, Subiculum, Entorhinal Cortex and Superior Temporal Gyrus in Alzheimer's Disease. Frontiers in cellular neuroscience. vol 15. 2021-10-01. PMID:34588956. |
eaat2 expression in the hippocampus, subiculum, entorhinal cortex and superior temporal gyrus in alzheimer's disease. |
2021-10-01 |
2023-08-13 |
human |
| Corey D M Fulton, David W C Beasley, Dennis A Bente, Kelly T Dinele. Long-term, West Nile virus-induced neurological changes: A comparison of patients and rodent models. Brain, behavior, & immunity - health. vol 7. 2021-10-01. PMID:34589866. |
initial infection in the hippocampus leads to neuronal dysfunction, synapse elimination, and astrocytosis, all of which contribute to memory loss, mimicking findings in neurodegenerative diseases such as alzheimer's disease (ad) and parkinson's disease (pd). |
2021-10-01 |
2023-08-13 |
human |