| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aynur Pekcanlar Akay, Halil Resmi, Sevay Alsen Güney, Handan Özek Erkuran, Gonca Özyurt, Enis Sargin, Ahmet Topuzoglu, Ali Evren Tufa. Serum brain-derived neurotrophic factor levels in treatment-naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week, observational pretest-posttest study. European child & adolescent psychiatry. vol 27. issue 1. 2018-05-02. PMID:28710695. |
although there were no statistically significant difference between the adhd group and healthy controls at baseline (p = 0.22), the increase of serum bdnf was statistically significant from baseline to endpoint in the adhd group (p = 0.04). |
2018-05-02 |
2023-08-13 |
Not clear |
| Aynur Pekcanlar Akay, Halil Resmi, Sevay Alsen Güney, Handan Özek Erkuran, Gonca Özyurt, Enis Sargin, Ahmet Topuzoglu, Ali Evren Tufa. Serum brain-derived neurotrophic factor levels in treatment-naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week, observational pretest-posttest study. European child & adolescent psychiatry. vol 27. issue 1. 2018-05-02. PMID:28710695. |
the mean serum bdnf levels at baseline and endpoint of the adhd group were 2626.33 ± 1528.05 and 3255.80 ± 1908.79 pg/ml, respectively. |
2018-05-02 |
2023-08-13 |
Not clear |
| Aynur Pekcanlar Akay, Halil Resmi, Sevay Alsen Güney, Handan Özek Erkuran, Gonca Özyurt, Enis Sargin, Ahmet Topuzoglu, Ali Evren Tufa. Serum brain-derived neurotrophic factor levels in treatment-naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week, observational pretest-posttest study. European child & adolescent psychiatry. vol 27. issue 1. 2018-05-02. PMID:28710695. |
the increase of serum bdnf levels with methylphenidate treatment after 8 weeks in boys with adhd may support the potential role of bdnf in the pathophysiology of adhd. |
2018-05-02 |
2023-08-13 |
Not clear |
| Aynur Pekcanlar Akay, Halil Resmi, Sevay Alsen Güney, Handan Özek Erkuran, Gonca Özyurt, Enis Sargin, Ahmet Topuzoglu, Ali Evren Tufa. Serum brain-derived neurotrophic factor levels in treatment-naïve boys with attention-deficit/hyperactivity disorder treated with methylphenidate: an 8-week, observational pretest-posttest study. European child & adolescent psychiatry. vol 27. issue 1. 2018-05-02. PMID:28710695. |
the role of bdnf in adhd subtypes in particular should be evaluated with further, larger studies. |
2018-05-02 |
2023-08-13 |
Not clear |
| Shih-Jen Tsa. Role of neurotrophic factors in attention deficit hyperactivity disorder. Cytokine & growth factor reviews. vol 34. 2018-02-09. PMID:27919646. |
preclinical evidence indicates that bdnf knockout mice are hyperactive, and an adhd rodent model exhibited decreased cerebral bdnf levels. |
2018-02-09 |
2023-08-13 |
mouse |
| Isabel Cubero-Millán, María-José Ruiz-Ramos, Antonio Molina-Carballo, Sylvia Martínez-Serrano, Luisa Fernández-López, Irene Machado-Casas, Pilar Tortosa-Pinto, Aida Ruiz-López, Juan-de-Dios Luna-Del-Castillo, José Uberos, Antonio Muñoz-Hoyo. BDNF concentrations and daily fluctuations differ among ADHD children and respond differently to methylphenidate with no relationship with depressive symptomatology. Psychopharmacology. vol 234. issue 2. 2017-12-05. PMID:27807606. |
bdnf concentrations and daily fluctuations differ among adhd children and respond differently to methylphenidate with no relationship with depressive symptomatology. |
2017-12-05 |
2023-08-13 |
Not clear |
| Isabel Cubero-Millán, María-José Ruiz-Ramos, Antonio Molina-Carballo, Sylvia Martínez-Serrano, Luisa Fernández-López, Irene Machado-Casas, Pilar Tortosa-Pinto, Aida Ruiz-López, Juan-de-Dios Luna-Del-Castillo, José Uberos, Antonio Muñoz-Hoyo. BDNF concentrations and daily fluctuations differ among ADHD children and respond differently to methylphenidate with no relationship with depressive symptomatology. Psychopharmacology. vol 234. issue 2. 2017-12-05. PMID:27807606. |
therefore, bdnf is a good candidate for interventions in the pathogenesis and/or treatment response of attention deficit hyperactivity disorder (adhd). |
2017-12-05 |
2023-08-13 |
Not clear |
| Z Hawi, T D R Cummins, J Tong, M Arcos-Burgos, Q Zhao, N Matthews, D P Newman, B Johnson, A Vance, H S Heussler, F Levy, S Easteal, N R Wray, E Kenny, D Morris, L Kent, M Gill, M A Bellgrov. Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study. Molecular psychiatry. vol 22. issue 4. 2017-10-10. PMID:27457811. |
a multi-marker gene-level analysis of rare (<1% frequency) single-nucleotide variants (snvs) revealed that the gene encoding brain-derived neurotrophic factor (bdnf) was associated with adhd at bonferroni corrected levels. |
2017-10-10 |
2023-08-13 |
Not clear |
| Z Hawi, T D R Cummins, J Tong, M Arcos-Burgos, Q Zhao, N Matthews, D P Newman, B Johnson, A Vance, H S Heussler, F Levy, S Easteal, N R Wray, E Kenny, D Morris, L Kent, M Gill, M A Bellgrov. Rare DNA variants in the brain-derived neurotrophic factor gene increase risk for attention-deficit hyperactivity disorder: a next-generation sequencing study. Molecular psychiatry. vol 22. issue 4. 2017-10-10. PMID:27457811. |
our results implicate bdnf as a genetic risk factor for adhd, potentially by virtue of its critical role in neurodevelopment and synaptic plasticity. |
2017-10-10 |
2023-08-13 |
Not clear |
| C P Zeni, S Tramontina, B W Aguiar, A Salatino-Oliveira, G F Pheula, A Sharma, L Stertz, C R Moreira Maia, M Hutz, F P Kapczinski, L A Rohd. BDNF Val66Met polymorphism and peripheral protein levels in pediatric bipolar disorder and attention-deficit/hyperactivity disorder. Acta psychiatrica Scandinavica. vol 134. issue 3. 2017-08-25. PMID:27209073. |
this study aimed to examine the bdnf gene polymorphism and potential alterations in bdnf serum levels in the pediatric adhd patients with or without comorbid bd illness. |
2017-08-25 |
2023-08-13 |
Not clear |
| b' Ayhan Bilgi\\xc3\\xa7, Aysun Toker, \\xc3\\x9cmit I\\xc5\\x9f\\xc4\\xb1k, \\xc4\\xb0brahim K\\xc4\\xb1l\\xc4\\xb1n\\xc3\\xa. Serum brain-derived neurotrophic factor, glial-derived neurotrophic factor, nerve growth factor, and neurotrophin-3 levels in children with attention-deficit/hyperactivity disorder. European child & adolescent psychiatry. vol 26. issue 3. 2017-03-29. PMID:27561780.' |
this study aimed to investigate whether there are differences in serum brain-derived neurotrophic factor (bdnf), glial-derived neurotrophic factor (gdnf), nerve growth factor (ngf), and neurotrophin-3 (ntf3) levels between children with adhd and healthy controls. |
2017-03-29 |
2023-08-13 |
Not clear |
| Jungyun Kim, Heamen Park, Seong-Lan Yu, Sungju Jee, Keun-Ah Cheon, Dong Ho Song, Seung Jun Kim, Woo-Young Im, Jaeku Kan. Effects of high-frequency repetitive transcranial magnetic stimulation (rTMS) on spontaneously hypertensive rats, an animal model of attention-deficit/hyperactivity disorder. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 53. 2017-03-27. PMID:27469434. |
in the present study, we applied repetitive transcranial magnetic stimulation (rtms), a non-invasive treatment used in a number of other psychiatric disorders, to spontaneously hypertensive rats (shrs), an animal model of adhd, in order to assess the efficacy of the treatment in modifying behavioural symptoms as well as levels of dopamine, noradrenaline, serotonin, and brain-derived neurotrophic factor (bdnf). |
2017-03-27 |
2023-08-13 |
rat |
| De-Yi Liu, Xue-Mei Shen, Fang-Fen Yuan, Ou-Yang Guo, Yan Zhong, Jian-Guo Chen, Ling-Qiang Zhu, Jing W. The Physiology of BDNF and Its Relationship with ADHD. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354496. |
the physiology of bdnf and its relationship with adhd. |
2016-08-10 |
2023-08-13 |
Not clear |
| De-Yi Liu, Xue-Mei Shen, Fang-Fen Yuan, Ou-Yang Guo, Yan Zhong, Jian-Guo Chen, Ling-Qiang Zhu, Jing W. The Physiology of BDNF and Its Relationship with ADHD. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354496. |
disrupting of bdnf and its downstream signals has been found in many neuropsychological diseases, including attention-deficit hyperactivity disorder (adhd), a common mental disorder which is prevalent in childhood. |
2016-08-10 |
2023-08-13 |
Not clear |
| De-Yi Liu, Xue-Mei Shen, Fang-Fen Yuan, Ou-Yang Guo, Yan Zhong, Jian-Guo Chen, Ling-Qiang Zhu, Jing W. The Physiology of BDNF and Its Relationship with ADHD. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354496. |
understanding the physiological functions of bdnf during neural development and its potential relationship with adhd will help us to elucidate the possible mechanisms of adhd and to develop therapeutic approaches for this disease. |
2016-08-10 |
2023-08-13 |
Not clear |
| De-Yi Liu, Xue-Mei Shen, Fang-Fen Yuan, Ou-Yang Guo, Yan Zhong, Jian-Guo Chen, Ling-Qiang Zhu, Jing W. The Physiology of BDNF and Its Relationship with ADHD. Molecular neurobiology. vol 52. issue 3. 2016-08-10. PMID:25354496. |
we also performed an association study on the functional genetic variation of bdnf and adhd by a case-control study in the chinese mainland population and revealed the potential correlation between bdnf and adhd which needs further research to confirm. |
2016-08-10 |
2023-08-13 |
Not clear |
| Josep A Ramos-Quiroga, Cristina Sánchez-Mora, Margarida Corominas, Iris Martínez, Víctor Barrau, Laura Prats, Miguel Casas, Marta Ribasé. [Neurotrophic factors and their importance in attention deficit hyperactivity disorde]. Revista de neurologia. vol 58 Suppl 1. 2016-01-04. PMID:25252662. |
this work reviews the results from the studies conducted to date on adhd and neurotrophic factors, especially brain-derived neurotrophic factor (bdnf). |
2016-01-04 |
2023-08-13 |
Not clear |
| Josep A Ramos-Quiroga, Cristina Sánchez-Mora, Margarida Corominas, Iris Martínez, Víctor Barrau, Laura Prats, Miguel Casas, Marta Ribasé. [Neurotrophic factors and their importance in attention deficit hyperactivity disorde]. Revista de neurologia. vol 58 Suppl 1. 2016-01-04. PMID:25252662. |
thus, although pharmacological studies suggest that the response to atomoxetine in adults with adhd is not directly mediated by the effect on the bdnf, reductions in bdnf levels in the plasma of adult patients with adhd have been reported. |
2016-01-04 |
2023-08-13 |
Not clear |
| Yaarit Simchon-Tenenbaum, Abraham Weizman, Moshe Rehav. Alterations in brain neurotrophic and glial factors following early age chronic methylphenidate and cocaine administration. Behavioural brain research. vol 282. 2015-09-21. PMID:25576963. |
bdnf protein level increase with age, as well as following stimulant treatments at early age may be relevant to the neurobiology and pharmacotherapy of adhd. |
2015-09-21 |
2023-08-13 |
rat |
| Namju Lee, Sok Park, Jongkyu Ki. Effects of hippotherapy on brain function, BDNF level, and physical fitness in children with ADHD. Journal of exercise nutrition & biochemistry. vol 19. issue 2. 2015-08-05. PMID:26244130. |
effects of hippotherapy on brain function, bdnf level, and physical fitness in children with adhd. |
2015-08-05 |
2023-08-13 |
Not clear |