Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Sum Yi Ma, Kin Ming Kwa. Size Anomaly and Alteration of GABAergic Enzymes Expressions in Cerebellum of a Valproic acid Mouse Model of Autism. Behavioural brain research. 2022-04-18. PMID:35436531. |
size anomaly and alteration of gabaergic enzymes expressions in cerebellum of a valproic acid mouse model of autism. |
2022-04-18 |
2023-08-13 |
mouse |
Sum Yi Ma, Kin Ming Kwa. Size Anomaly and Alteration of GABAergic Enzymes Expressions in Cerebellum of a Valproic acid Mouse Model of Autism. Behavioural brain research. 2022-04-18. PMID:35436531. |
however, studies in the mechanism for the involvement of the cerebellum in autism remained speculative. |
2022-04-18 |
2023-08-13 |
mouse |
Sum Yi Ma, Kin Ming Kwa. Size Anomaly and Alteration of GABAergic Enzymes Expressions in Cerebellum of a Valproic acid Mouse Model of Autism. Behavioural brain research. 2022-04-18. PMID:35436531. |
this study aimed to investigate the cerebellar structure and determine the expression of rate-limiting gabaergic enzymes in gaba signalling of the autism cerebellum. |
2022-04-18 |
2023-08-13 |
mouse |
Sum Yi Ma, Kin Ming Kwa. Size Anomaly and Alteration of GABAergic Enzymes Expressions in Cerebellum of a Valproic acid Mouse Model of Autism. Behavioural brain research. 2022-04-18. PMID:35436531. |
thus, our findings provide supporting evidence that cerebellum impairment could be an etiology of environmentally induced autism. |
2022-04-18 |
2023-08-13 |
mouse |
Sum Yi Ma, Kin Ming Kwa. Size Anomaly and Alteration of GABAergic Enzymes Expressions in Cerebellum of a Valproic acid Mouse Model of Autism. Behavioural brain research. 2022-04-18. PMID:35436531. |
changes in cerebellar structure and the altered gabaergic enzymes in the cerebellum provide targets for future therapeutic studies in idiopathic autism. |
2022-04-18 |
2023-08-13 |
mouse |
Jennifer M Gibson, Cleone P Howland, Chongyu Ren, Cyrena Howland, Alexandra Vernino, Peter T Tsa. A critical period for development of cerebellar-mediated autism-relevant social behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-02-22. PMID:35190469. |
the cerebellum has been increasingly implicated in autism spectrum disorder (asd) with many asd-linked genes impacting both cerebellar function and development. |
2022-02-22 |
2023-08-13 |
mouse |
Viera Kútna, Valerie Bríd O'Leary, Cyril Hoschl, Saak V Ovsepia. Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism research : official journal of the International Society for Autism Research. 2022-02-18. PMID:35178882. |
lay summary: this study elucidates the impact of constitutive mtorc1 hyperactivity on cerebellar morphology and cellular organization in a rat model of autism and epilepsy. |
2022-02-18 |
2023-08-13 |
human |
Viera Kútna, Valerie Bríd O'Leary, Cyril Hoschl, Saak V Ovsepia. Cerebellar demyelination and neurodegeneration associated with mTORC1 hyperactivity may contribute to the developmental onset of autism-like neurobehavioral phenotype in a rat model. Autism research : official journal of the International Society for Autism Research. 2022-02-18. PMID:35178882. |
the described changes provide new indications for the putative mechanisms underlying cerebellar impairments with their age-related onset, which may contribute to the pathobiology of autism, epilepsy, and related disorders. |
2022-02-18 |
2023-08-13 |
human |
Giordano D'Urso, Elena Toscano, Veronica Sanges, Anne Sauvaget, Christine E Sheffer, Maria Pia Riccio, Roberta Ferrucci, Felice Iasevoli, Alberto Priori, Carmela Bravaccio, Andrea de Bartolomei. Cerebellar Transcranial Direct Current Stimulation in Children with Autism Spectrum Disorder: A Pilot Study on Efficacy, Feasibility, Safety, and Unexpected Outcomes in Tic Disorder and Epilepsy. Journal of clinical medicine. vol 11. issue 1. 2022-01-11. PMID:35011884. |
cerebellar transcranial direct current stimulation in children with autism spectrum disorder: a pilot study on efficacy, feasibility, safety, and unexpected outcomes in tic disorder and epilepsy. |
2022-01-11 |
2023-08-13 |
Not clear |
Qian-Qian Kang, Xu Li, Guang-Lei Tong, Ya-Lan Fan, Lei Sh. Magnetic resonance spectroscopy features of the thalamus and the cerebellum and their association with clinical features in children with autism spectrum disorder: a prospective study. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 23. issue 12. 2021-12-16. PMID:34911608. |
magnetic resonance spectroscopy features of the thalamus and the cerebellum and their association with clinical features in children with autism spectrum disorder: a prospective study. |
2021-12-16 |
2023-08-13 |
Not clear |
Qian-Qian Kang, Xu Li, Guang-Lei Tong, Ya-Lan Fan, Lei Sh. Magnetic resonance spectroscopy features of the thalamus and the cerebellum and their association with clinical features in children with autism spectrum disorder: a prospective study. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 23. issue 12. 2021-12-16. PMID:34911608. |
to study the changes in biochemical metabolites in the thalamus and the cerebellum and their association with clinical features in children with autism spectrum disorder (asd). |
2021-12-16 |
2023-08-13 |
Not clear |
Marta Fernández, Carlos A Sánchez-León, Javier Llorente, Teresa Sierra-Arregui, Shira Knafo, Javier Márquez-Ruiz, Olga Peñagarikan. Altered Cerebellar Response to Somatosensory Stimuli in the eNeuro. vol 8. issue 5. 2021-12-10. PMID:34593517. |
altered cerebellar response to somatosensory stimuli in the atypical sensory processing is currently included within the diagnostic criteria of autism. |
2021-12-10 |
2023-08-13 |
mouse |
Marta Fernández, Carlos A Sánchez-León, Javier Llorente, Teresa Sierra-Arregui, Shira Knafo, Javier Márquez-Ruiz, Olga Peñagarikan. Altered Cerebellar Response to Somatosensory Stimuli in the eNeuro. vol 8. issue 5. 2021-12-10. PMID:34593517. |
interestingly, cerebellar malformations are among the most replicated features found in postmortem brain of individuals with autism. |
2021-12-10 |
2023-08-13 |
mouse |
Marta Fernández, Carlos A Sánchez-León, Javier Llorente, Teresa Sierra-Arregui, Shira Knafo, Javier Márquez-Ruiz, Olga Peñagarikan. Altered Cerebellar Response to Somatosensory Stimuli in the eNeuro. vol 8. issue 5. 2021-12-10. PMID:34593517. |
we studied sensory processing in the cerebellum in a mouse model of autism, knock-out (ko) for the |
2021-12-10 |
2023-08-13 |
mouse |
Nana J Okada, Janelle Liu, Tawny Tsang, Erin Nosco, Nicole M McDonald, Kaitlin K Cummings, Jiwon Jung, Genevieve Patterson, Susan Y Bookheimer, Shulamite A Green, Shafali S Jeste, Mirella Daprett. Atypical cerebellar functional connectivity at 9 months of age predicts delayed socio-communicative profiles in infants at high and low risk for autism. Journal of child psychology and psychiatry, and allied disciplines. 2021-12-09. PMID:34882790. |
atypical cerebellar functional connectivity at 9 months of age predicts delayed socio-communicative profiles in infants at high and low risk for autism. |
2021-12-09 |
2023-08-13 |
Not clear |
Nana J Okada, Janelle Liu, Tawny Tsang, Erin Nosco, Nicole M McDonald, Kaitlin K Cummings, Jiwon Jung, Genevieve Patterson, Susan Y Bookheimer, Shulamite A Green, Shafali S Jeste, Mirella Daprett. Atypical cerebellar functional connectivity at 9 months of age predicts delayed socio-communicative profiles in infants at high and low risk for autism. Journal of child psychology and psychiatry, and allied disciplines. 2021-12-09. PMID:34882790. |
indeed, cerebellar atypicalities are commonly reported in autism spectrum disorder (asd), a neurodevelopmental disorder characterized by socio-communicative impairments. |
2021-12-09 |
2023-08-13 |
Not clear |
Silvia Clausi, Giusy Olivito, Libera Siciliano, Michela Lupo, Fiorenzo Laghi, Roberto Baiocco, Maria Leggi. The cerebellum is linked to theory of mind alterations in autism. A direct clinical and MRI comparison between individuals with autism and cerebellar neurodegenerative pathologies. Autism research : official journal of the International Society for Autism Research. vol 14. issue 11. 2021-11-29. PMID:34374492. |
the cerebellum is linked to theory of mind alterations in autism. |
2021-11-29 |
2023-08-13 |
human |
Silvia Clausi, Giusy Olivito, Libera Siciliano, Michela Lupo, Fiorenzo Laghi, Roberto Baiocco, Maria Leggi. The cerebellum is linked to theory of mind alterations in autism. A direct clinical and MRI comparison between individuals with autism and cerebellar neurodegenerative pathologies. Autism research : official journal of the International Society for Autism Research. vol 14. issue 11. 2021-11-29. PMID:34374492. |
a direct clinical and mri comparison between individuals with autism and cerebellar neurodegenerative pathologies. |
2021-11-29 |
2023-08-13 |
human |
Silvia Clausi, Giusy Olivito, Libera Siciliano, Michela Lupo, Fiorenzo Laghi, Roberto Baiocco, Maria Leggi. The cerebellum is linked to theory of mind alterations in autism. A direct clinical and MRI comparison between individuals with autism and cerebellar neurodegenerative pathologies. Autism research : official journal of the International Society for Autism Research. vol 14. issue 11. 2021-11-29. PMID:34374492. |
in recent years, structural and functional alterations in the cerebellum have been reported in autism spectrum disorder (asd). |
2021-11-29 |
2023-08-13 |
human |
Silvia Clausi, Giusy Olivito, Libera Siciliano, Michela Lupo, Fiorenzo Laghi, Roberto Baiocco, Maria Leggi. The cerebellum is linked to theory of mind alterations in autism. A direct clinical and MRI comparison between individuals with autism and cerebellar neurodegenerative pathologies. Autism research : official journal of the International Society for Autism Research. vol 14. issue 11. 2021-11-29. PMID:34374492. |
lay summary: the present work will critically advance current knowledge about the cerebellar role in theory of mind alterations of autism spectrum disorder (asd), in particular, elucidating the presence of common cerebellar structural abnormalities in asd and cerebellar individuals that may underlie specific mentalizing alterations. |
2021-11-29 |
2023-08-13 |
human |