| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Amy Niego, Antonio Benítez-Burrac. Autism and Williams syndrome: Dissimilar socio-cognitive profiles with similar patterns of abnormal gene expression in the blood. Autism : the international journal of research and practice. vol 25. issue 2. 2021-07-28. PMID:33143449. |
differentially expressed genes are involved in aspects of brain development and function (particularly dendritogenesis) and are expressed in brain areas (particularly the cerebellum, the thalamus, and the striatum) of relevance for the autism spectrum disorder and the williams syndrome etiopathogenesis. |
2021-07-28 |
2023-08-13 |
human |
| Joel Crucitti, Christian Hyde, Peter G Enticott, Mark A Stoke. Are Vermal Lobules VI-VII Smaller in Autism Spectrum Disorder? Cerebellum (London, England). vol 19. issue 5. 2021-07-09. PMID:32445170. |
cerebellar volume, in particular vermal lobule areas vi-vii, have been extensively researched in individuals with autism spectrum disorder (asd), although findings are often unclear. |
2021-07-09 |
2023-08-13 |
Not clear |
| Claudia D Tesche, Jon M Houc. Discordant Alpha-Band Transcranial Alternating Current Stimulation Affects Cortico-Cortical and Cortico-Cerebellar Connectivity. Brain connectivity. vol 10. issue 4. 2021-06-15. PMID:32216454. |
understanding a potential compensatory mechanism involving short-term plasticity in the cerebellum may be critical to developing potential clinical applications of tacs, particularly for disorders such as autism that are characterized by both atypical cortical and cerebellar dynamics. |
2021-06-15 |
2023-08-13 |
Not clear |
| Janusz Frackowiak, Bozena Mazur-Kolecka, Pankaj Mehta, Jerzy Wegie. Enhanced accumulation of N-terminally truncated Aβ with and without pyroglutamate-11 modification in parvalbumin-expressing GABAergic neurons in idiopathic and dup15q11.2-q13 autism. Acta neuropathologica communications. vol 8. issue 1. 2021-05-31. PMID:32345355. |
products of app processing - n-terminally truncated amyloid-β peptide (n-tr-aβ) species - are accumulated in autism in neurons and glia in the cortex, cerebellum, and subcortical structures of the brain. |
2021-05-31 |
2023-08-13 |
Not clear |
| Owen Y Chao, Ezequiel Marron Fernandez de Velasco, Salil Saurav Pathak, Swati Maitra, Hao Zhang, Lisa Duvick, Kevin Wickman, Harry T Orr, Hirokazu Hirai, Yi-Mei Yan. Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 7. 2021-05-27. PMID:32179875. |
targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. |
2021-05-27 |
2023-08-13 |
mouse |
| Yanpei Wang, Qinfang Xu, Chenyi Zuo, Liying Zhao, Lei Ha. Longitudinal Changes of Cerebellar Thickness in Autism Spectrum Disorder. Neuroscience letters. vol 728. 2021-05-17. PMID:32278028. |
longitudinal changes of cerebellar thickness in autism spectrum disorder. |
2021-05-17 |
2023-08-13 |
Not clear |
| Yanpei Wang, Qinfang Xu, Chenyi Zuo, Liying Zhao, Lei Ha. Longitudinal Changes of Cerebellar Thickness in Autism Spectrum Disorder. Neuroscience letters. vol 728. 2021-05-17. PMID:32278028. |
many studies have reported abnormal cerebellar volume in patients with autism spectrum disorder (asd) and that this abnormal volume can change with age. |
2021-05-17 |
2023-08-13 |
Not clear |
| Yanpei Wang, Qinfang Xu, Chenyi Zuo, Liying Zhao, Lei Ha. Longitudinal Changes of Cerebellar Thickness in Autism Spectrum Disorder. Neuroscience letters. vol 728. 2021-05-17. PMID:32278028. |
to explore the relationship between cerebellar lobular thickness and the symptoms of asd, the correlation of autism diagnostic observation schedule (ados) score with lobular thickness data was calculated. |
2021-05-17 |
2023-08-13 |
Not clear |
| Li-Da Su, Fang-Xiao Xu, Xin-Tai Wang, Xin-Yu Cai, Ying She. Cerebellar Dysfunction, Cerebro-cerebellar Connectivity and Autism Spectrum Disorders. Neuroscience. vol 462. 2021-05-14. PMID:32450293. |
in particular, the cerebellum has been recognized as one of key brain regions affected in autism spectrum disorder (asd). |
2021-05-14 |
2023-08-13 |
mouse |
| Wing Yip Tam, Xia Wang, Andy S K Cheng, Kwok-Kuen Cheun. In Search of Molecular Markers for Cerebellar Neurons. International journal of molecular sciences. vol 22. issue 4. 2021-04-15. PMID:33673348. |
maldevelopment and dysfunction of the cerebellum lead to cerebellar ataxia and may even be associated with autism, depression, and cognitive deficits. |
2021-04-15 |
2023-08-13 |
Not clear |
| Katharine J Liang, Erik S Carlso. Resistance, vulnerability and resilience: A review of the cognitive cerebellum in aging and neurodegenerative diseases. Neurobiology of learning and memory. vol 170. 2021-04-12. PMID:30630042. |
the cerebellum is well known for comparing internal representations of information with observed outcomes and providing real-time feedback to cortical regions, a critical function that is disturbed in neuropsychiatric disorders such as intellectual disability, schizophrenia, dementia, and autism, and required for cognitive domains such as working memory. |
2021-04-12 |
2023-08-13 |
Not clear |
| María Elena Rodríguez-García, Francisco Javier Cotrina-Vinagre, María de Los Ángeles Gómez-Cano, Ana Martínez de Aragón, Elena Martín-Hernández, Francisco Martínez-Azorí. MAST1 variant causes mega-corpus-callosum syndrome with cortical malformations but without cerebellar hypoplasia. American journal of medical genetics. Part A. vol 182. issue 6. 2021-01-28. PMID:32198973. |
only 12 patients have been identified worldwide with 10 different variants in this gene: six patients with mega-corpus-callosum syndrome with cerebellar hypoplasia and cortical malformations; two patients with microcephaly and cerebellar hypoplasia; two patients with autism, one patient with diplegia, and one patient with microcephaly and dysmorphism. |
2021-01-28 |
2023-08-13 |
Not clear |
| Ilana Chilton, Volkan Okur, Giuseppina Vitiello, Angelo Selicorni, Milena Mariani, Alice Goldenberg, Thomas Husson, Dominique Campion, Klaske D Lichtenbelt, Koen van Gassen, Michelle Steinraths, Jennifer Rice, Elizabeth R Roeder, Rebecca O Littlejohn, Myriam Srour, Guillaume Sebire, Andrea Accogli, Delphine Héron, Solveig Heide, Caroline Nava, Christel Depienne, Austin Larson, Dmitriy Niyazov, Meron Azage, George Hoganson, Jennifer Burton, Eric T Rush, Janda L Jenkins, Carol J Saunders, Isabelle Thiffault, Joseph T Alaimo, Julie Fleischer, Daniel Groepper, Karen W Gripp, Wendy K Chun. De novo heterozygous missense and loss-of-function variants in CDC42BPB are associated with a neurodevelopmental phenotype. American journal of medical genetics. Part A. vol 182. issue 5. 2021-01-12. PMID:32031333. |
we identified 12 heterozygous predicted deleterious variants in cdc42bpb (9 missense, 2 frameshift, and 1 nonsense) in 14 unrelated individuals (confirmed de novo in 11/14) with neurodevelopmental disorders including developmental delay/intellectual disability, autism, hypotonia, and structural brain abnormalities including cerebellar vermis hypoplasia and agenesis/hypoplasia of the corpus callosum. |
2021-01-12 |
2023-08-13 |
Not clear |
| Rachel E W Smith, Jason A Avery, Gregory L Wallace, Lauren Kenworthy, Stephen J Gotts, Alex Marti. Sex Differences in Resting-State Functional Connectivity of the Cerebellum in Autism Spectrum Disorder. Frontiers in human neuroscience. vol 13. 2021-01-09. PMID:31024276. |
sex differences in resting-state functional connectivity of the cerebellum in autism spectrum disorder. |
2021-01-09 |
2023-08-13 |
Not clear |
| b' Tam\\xc3\\xa1s Spis\\xc3\\xa1k, Viktor Rom\\xc3\\xa1n, Edit Papp, Rita Kedves, Katalin S\\xc3\\xa1ghy, Cec\\xc3\\xadlia Katalin Cs\\xc3\\xb6lle, Anita Varga, D\\xc3\\xa1vid Gaj\\xc3\\xa1ri, Gabriella Nyitrai, Zs\\xc3\\xb3fia Spis\\xc3\\xa1k, Zsigmond Tam\\xc3\\xa1s Kincses, Gy\\xc3\\xb6rgy L\\xc3\\xa9vay, Bal\\xc3\\xa1zs Lendvai, Andr\\xc3\\xa1s Czurk\\xc3\\xb. Purkinje cell number-correlated cerebrocerebellar circuit anomaly in the valproate model of autism. Scientific reports. vol 9. issue 1. 2020-10-22. PMID:31239528.' |
while cerebellar alterations may play a crucial role in the development of core autism spectrum disorder (asd) symptoms, their pathophysiology on the function of cerebrocerebellar circuit loops is largely unknown. |
2020-10-22 |
2023-08-13 |
rat |
| Garrett J Cardon, Susan Hepburn, Donald C Roja. Structural Covariance of Sensory Networks, the Cerebellum, and Amygdala in Autism Spectrum Disorder. Frontiers in neurology. vol 8. 2020-10-01. PMID:29230189. |
structural covariance of sensory networks, the cerebellum, and amygdala in autism spectrum disorder. |
2020-10-01 |
2023-08-13 |
human |
| S Hossein Fatemi, Dean F Wong, James R Brašić, Hiroto Kuwabara, Anil Mathur, Timothy D Folsom, Suma Jacob, George M Realmuto, José V Pardo, Susanne Le. Metabotropic glutamate receptor 5 tracer [ Cerebellum & ataxias. vol 5. 2020-10-01. PMID:29449954. |
postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mglur5) in cerebellar vermis and prefrontal cortex of individuals with autism. |
2020-10-01 |
2023-08-13 |
Not clear |
| Qianling Hou, Yan Wang, Yingbo Li, Di Chen, Feng Yang, Shali Wan. A Developmental Study of Abnormal Behaviors and Altered GABAergic Signaling in the VPA-Treated Rat Model of Autism. Frontiers in behavioral neuroscience. vol 12. 2020-10-01. PMID:30186123. |
our findings indicate an impaired gabaergic system could be a major etiological factor occurring in the cerebral cortex, hc and cerebellum of human cases of autism, which suggests enhancement of gaba signaling would be a promising therapeutic target for its treatment. |
2020-10-01 |
2023-08-13 |
human |
| Ramit Sharma, Saloni Rahi, Sidharth Meha. Neuroprotective potential of solanesol in intracerebroventricular propionic acid induced experimental model of autism: Insights from behavioral and biochemical evidence. Toxicology reports. vol 6. 2020-10-01. PMID:31763180. |
neuropathological hallmarks that associated with autism are mitochondrial dysfunction, oxidative stress, neuroinflammation, neuro-excitation, abnormal synapse formation, overexpression of glial cells in specific brain regions like cerebellum, cerebral cortex, amygdala, and hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| André Fujita, Maciel C Vidal, Daniel Y Takahash. A Statistical Method to Distinguish Functional Brain Networks. Frontiers in neuroscience. vol 11. 2020-09-30. PMID:28261045. |
anogva identified the cerebellar functional sub-network as statistically different between controls and autism ( |
2020-09-30 |
2023-08-13 |
human |