| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lucia Ciranna, Maria Vincenza Catani. 5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders. Frontiers in cellular neuroscience. vol 8. 2014-09-15. PMID:25221471. |
we have recently shown that 5-ht7 receptor activation rescues hippocampal synaptic plasticity in a mouse model of fragile x syndrome, a monogenic cause of autism. |
2014-09-15 |
2023-08-13 |
mouse |
| Yun Tian, Yasushi Yabuki, Shigeki Moriguchi, Kohji Fukunaga, Pei-Jiang Mao, Ling-Juan Hong, Ying-Mei Lu, Rui Wang, Muhammad Masood Ahmed, Mei-Hua Liao, Ji-Yun Huang, Rui-Ting Zhang, Tian-Yi Zhou, Sen Long, Feng Ha. Melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism. Journal of pineal research. vol 56. issue 1. 2014-08-25. PMID:23952810. |
melatonin reverses the decreases in hippocampal protein serine/threonine kinases observed in an animal model of autism. |
2014-08-25 |
2023-08-12 |
rat |
| Naama Barnea-Goraly, Thomas W Frazier, Lucia Piacenza, Nancy J Minshew, Matcheri S Keshavan, Allan L Reiss, Antonio Y Harda. A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism. Progress in neuro-psychopharmacology & biological psychiatry. vol 48. 2014-08-01. PMID:24075822. |
a preliminary longitudinal volumetric mri study of amygdala and hippocampal volumes in autism. |
2014-08-01 |
2023-08-12 |
Not clear |
| Naama Barnea-Goraly, Thomas W Frazier, Lucia Piacenza, Nancy J Minshew, Matcheri S Keshavan, Allan L Reiss, Antonio Y Harda. A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism. Progress in neuro-psychopharmacology & biological psychiatry. vol 48. 2014-08-01. PMID:24075822. |
hippocampal volume, however, does not appear to have age-related changes, and it is unclear whether individuals with autism have volumetric differences in this structure. |
2014-08-01 |
2023-08-12 |
Not clear |
| Naama Barnea-Goraly, Thomas W Frazier, Lucia Piacenza, Nancy J Minshew, Matcheri S Keshavan, Allan L Reiss, Antonio Y Harda. A preliminary longitudinal volumetric MRI study of amygdala and hippocampal volumes in autism. Progress in neuro-psychopharmacology & biological psychiatry. vol 48. 2014-08-01. PMID:24075822. |
the goal of this pilot investigation is to characterize the developmental trajectories of the amygdala and hippocampus in children with autism between the ages of 8 and 14years and to examine clinical correlates of volume change. |
2014-08-01 |
2023-08-12 |
Not clear |
| Dorothy M Jones-Davis, Mu Yang, Eric Rider, Nathan C Osbun, Gilberto J da Gente, Jiang Li, Adam M Katz, Michael D Weber, Saunak Sen, Jacqueline Crawley, Elliott H Sher. Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism. PloS one. vol 8. issue 4. 2013-11-26. PMID:23613947. |
we used the btbr t⁺ tf/j (btbr) strain, exhibiting fully penetrant agcc, a diminished hippocampal commissure, and abnormal behaviors that may have face validity to autism, to study the genetic basis of these disorders. |
2013-11-26 |
2023-08-12 |
mouse |
| Mohammad Amin Edalatmanesh, Haniyeh Nikfarjam, Farzaneh Vafaee, Marzieh Moghada. Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism. Brain research. vol 1526. 2013-10-23. PMID:23806776. |
increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism. |
2013-10-23 |
2023-08-12 |
rat |
| Mohammad Amin Edalatmanesh, Haniyeh Nikfarjam, Farzaneh Vafaee, Marzieh Moghada. Increased hippocampal cell density and enhanced spatial memory in the valproic acid rat model of autism. Brain research. vol 1526. 2013-10-23. PMID:23806776. |
this study provides further evidence to support the notion that spatial memory and hippocampal cell density are increased in this animal model of autism. |
2013-10-23 |
2023-08-12 |
rat |
| Mark S Brown, Debra Singel, Susan Hepburn, Donald C Roja. Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study. Autism research : official journal of the International Society for Autism Research. vol 6. issue 1. 2013-08-27. PMID:23166003. |
increased glutamate levels have been reported in the hippocampal and frontal regions of persons with autism using proton magnetic resonance spectroscopy ((1)h-mrs). |
2013-08-27 |
2023-08-12 |
human |
| Mark S Brown, Debra Singel, Susan Hepburn, Donald C Roja. Increased glutamate concentration in the auditory cortex of persons with autism and first-degree relatives: a (1)H-MRS study. Autism research : official journal of the International Society for Autism Research. vol 6. issue 1. 2013-08-27. PMID:23166003. |
the elevation in glx in autism is consistent with prior mrs data in the hippocampus and frontal lobe and may suggest increased cortical excitability. |
2013-08-27 |
2023-08-12 |
human |
| Roberta Bristot Silvestrin, Victorio Bambini-Junior, Fabiana Galland, Larissa Daniele Bobermim, André Quincozes-Santos, Renata Torres Abib, Caroline Zanotto, Cristiane Batassini, Giovana Brolese, Carlos-Alberto Gonçalves, Rudimar Riesgo, Carmem Gottfrie. Animal model of autism induced by prenatal exposure to valproate: altered glutamate metabolism in the hippocampus. Brain research. vol 1495. 2013-07-22. PMID:23219577. |
animal model of autism induced by prenatal exposure to valproate: altered glutamate metabolism in the hippocampus. |
2013-07-22 |
2023-08-12 |
rat |
| Helen S Bateup, Caroline A Johnson, Cassandra L Denefrio, Jessica L Saulnier, Karl Kornacker, Bernardo L Sabatin. Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis. Neuron. vol 78. issue 3. 2013-07-09. PMID:23664616. |
here, we examine the function of the tuberous sclerosis complex (tsc)-mtor signaling pathway, a common target of mutations associated with epilepsy and autism spectrum disorder, in regulating activity-dependent processes in the mouse hippocampus. |
2013-07-09 |
2023-08-12 |
mouse |
| Rocco Pizzarelli, Enrico Cherubin. Developmental regulation of GABAergic signalling in the hippocampus of neuroligin 3 R451C knock-in mice: an animal model of Autism. Frontiers in cellular neuroscience. vol 7. 2013-06-14. PMID:23761734. |
developmental regulation of gabaergic signalling in the hippocampus of neuroligin 3 r451c knock-in mice: an animal model of autism. |
2013-06-14 |
2023-08-12 |
mouse |
| Stephen Grossber. Adaptive Resonance Theory: how a brain learns to consciously attend, learn, and recognize a changing world. Neural networks : the official journal of the International Neural Network Society. vol 37. 2013-05-22. PMID:23149242. |
art provides functional and mechanistic explanations of such diverse topics as laminar cortical circuitry; invariant object and scenic gist learning and recognition; prototype, surface, and boundary attention; gamma and beta oscillations; learning of entorhinal grid cells and hippocampal place cells; computation of homologous spatial and temporal mechanisms in the entorhinal-hippocampal system; vigilance breakdowns during autism and medial temporal amnesia; cognitive-emotional interactions that focus attention on valued objects in an adaptively timed way; item-order-rank working memories and learned list chunks for the planning and control of sequences of linguistic, spatial, and motor information; conscious speech percepts that are influenced by future context; auditory streaming in noise during source segregation; and speaker normalization. |
2013-05-22 |
2023-08-12 |
Not clear |
| C E Adams, J C Yonchek, K M Schulz, S L Graw, J Stitzel, P U Teschke, K E Steven. Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases. Neuroscience. vol 207. 2012-11-27. PMID:22314319. |
these data suggest that reduced chrna7 expression may contribute to the abnormalities in hippocampal inhibitory circuits observed in schizophrenia, autism, and/or epilepsy. |
2012-11-27 |
2023-08-12 |
mouse |
| Jacob Ellegood, R Mark Henkelman, Jason P Lerc. Neuroanatomical Assessment of the Integrin β3 Mouse Model Related to Autism and the Serotonin System Using High Resolution MRI. Frontiers in psychiatry. vol 3. 2012-10-02. PMID:22557981. |
a number of interesting differences relevant to autism were discovered including a smaller corpus callosum volume and bilateral decreases in the hippocampus, striatum, and cerebellum. |
2012-10-02 |
2023-08-12 |
mouse |
| Letten F Saugsta. Further evidence that infantile autism is a chronic psychosis distinguished by a deficient delayed response function affecting the connections between hippocampus and singulum in its center, the SMA and the inhibitory Purkinje cells in cerebellum. Nutrition and health. vol 21. issue 1. 2012-08-02. PMID:22544774. |
further evidence that infantile autism is a chronic psychosis distinguished by a deficient delayed response function affecting the connections between hippocampus and singulum in its center, the sma and the inhibitory purkinje cells in cerebellum. |
2012-08-02 |
2023-08-12 |
Not clear |
| Louise Harvey, Patricia Boks. A stereological comparison of GAD67 and reelin expression in the hippocampal stratum oriens of offspring from two mouse models of maternal inflammation during pregnancy. Neuropharmacology. vol 62. issue 4. 2012-07-27. PMID:22178614. |
altered expression of glutamic acid decarboxylase (gad67) and reelin in the hippocampus has been reported in post-mortem studies of people with schizophrenia or autism. |
2012-07-27 |
2023-08-12 |
mouse |
| Anahita Amiri, Woosung Cho, Jing Zhou, Shari G Birnbaum, Christopher M Sinton, Renée M McKay, Luis F Parad. Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 17. 2012-06-25. PMID:22539849. |
moreover, the role of hippocampus, one of the brain regions where adult neurogenesis occurs, in development of autism is not clear. |
2012-06-25 |
2023-08-12 |
mouse |
| Clodagh M Murphy, Q Deeley, E M Daly, C Ecker, F M O'Brien, B Hallahan, E Loth, F Toal, S Reed, S Hales, D M Robertson, M C Craig, D Mullins, G J Barker, T Lavender, P Johnston, K C Murphy, D G Murph. Anatomy and aging of the amygdala and hippocampus in autism spectrum disorder: an in vivo magnetic resonance imaging study of Asperger syndrome. Autism research : official journal of the International Society for Autism Research. vol 5. issue 1. 2012-06-22. PMID:21948742. |
anatomy and aging of the amygdala and hippocampus in autism spectrum disorder: an in vivo magnetic resonance imaging study of asperger syndrome. |
2012-06-22 |
2023-08-12 |
Not clear |